Development And Preliminary Evaluation Of PCM Thermal Energy Storage For Air Cooling In Buildings

This study presents the development of a real-scale latent heat thermal energy storage (TES) device based on an air-PCM (phase change material) heat exchanger. The device uses the outdoor ambient temperature difference between night and day to refresh the indoor air and shift or completely avoid the use of air-conditioning in air-cooling in the building sector. The design is based on an extensive set of numerical simulations, performed by the commercial software ANSYS Fluent, focused on a parametric study allowing to identify the optimum value of different design parameters in order to have 10 hours of temperature shift. The numerical simulations were supported by experimental measurements done with a small-scale test rig. Additionally, the thermal response of the PCM to cooling and heating was also studied in a controlled temperature and humidity environment

High-bootstrap, noninductively sustained electron internal transport barriers in the Tokamak a Configuration Variable

Important ingredients of the advanced-tokamak route to fusion have been explored in depth in the Tokamak a Configuration Variable [F. Hofmann, J. B. Lister, M. Anton , Plasma Phys. Controlled Fusion 36, B277 (1994)] over the past two years. Using a uniquely powerful and flexible electron-cyclotron resonance heating (ECRH) system as the primary actuator, fully noninductive, steady-state electron internal transport barrier discharges have been generated with an electron-energy confinement time up to five times longer than in L mode, poloidal beta up to 2.4, and bootstrap fraction up to 75%. Interpretative transport modeling confirms that the safety factor profile is nonmonotonic in these discharges. The formation of the barrier is a discrete event resulting in rapid and localized confinement improvement consistent with the time and location of magnetic-shear reversal. In steady state, however, the confinement quality appears to depend on the current gradient in a broader negative-shear region enclosed by the barrier, improving with increasing shear: in particular, the width and depth of the barrier can be controlled and finely tuned, along a magnetohydrodynamic-stable path, by manipulating the current profile with ECRH (six independently steerable 0.45 MW launchers). The crucial role of the current profile has been clearly demonstrated by applying small Ohmic current perturbations which dramatically alter the properties of the barrier, enhancing or reducing the confinement with negative and positive current, respectively, with negligible Ohmic heating. These results are in agreement with theoretical estimates: first-principle-based numerical simulations of microinstability dynamics and turbulence-driven transport predict a substantial suppression of turbulence and anomalous energy diffusivity near the location of the minimum in the safety factor. (c) 2005 American Institute of Physics

Diphenyl Urea Derivatives as Inhibitors of Transketolase: A Structure-Based Virtual Screening

Transketolase is an enzyme involved in a critical step of the non-oxidative branch of the pentose phosphate pathway whose inhibition could lead to new anticancer drugs. Here, we report new human transketolase inhibitors, based on the phenyl urea scaffold, found by applying structure-based virtual screening. These inhibitors are designed to cover a hot spot in the dimerization interface of the homodimer of the enzyme, providing for the first time compounds with a suggested novel binding mode not based on mimicking the thiamine pyrophosphate cofactor

Illegal births and legal abortions – the case of China

BACKGROUND: China has a national policy regulating the number of children that a woman is allowed to have. The central concept at the individual level application is "illegal pregnancy". The purpose of this article is to describe and problematicize the concept of illegal pregnancy and its use in practice. METHODS: Original texts and previous published and unpublished reports and statistics were used. RESULTS: By 1979 the Chinese population policy was clearly a policy of controlling population growth. For a pregnancy to be legal, it has to be defined as such according to the family-level eligibility rules, and in some places it has to be within the local quota. Enforcement of the policy has been pursued via the State Family Planning (FP) Commission and the Communist Party (CP), both of which have a functioning vertical structure down to the lowest administrative units. There are various incentives and disincentives for families to follow the policy. An extensive system has been created to keep the contraceptive use and pregnancy status of all married women at reproductive age under constant surveillance. In the early 1990s FP and CP officials were made personally responsible for meeting population targets. Since 1979, abortion has been available on request, and the ratio of legal abortions to birth increased in the 1980s and declined in the 1990s. Similar to what happens in other Asian countries with low fertility rates and higher esteem for boys, both national- and local-level data show that an unnaturally greater number of boys than girls are registered as having been born. CONCLUSION: Defining a pregnancy as "illegal" and carrying out the surveillance of individual women are phenomena unique in China, but this does not apply to other features of the policy. The moral judgment concerning the policy depends on the basic question of whether reproduction should be considered as an individual or social decision