Classification of Text Documents Using a Logical Analysis Approach.

The main problem investigated in this dissertation is as follows: Given are two samples of documents each from one of two disjoint collections of documents. The question is how to obtain a set of patterns of text features that make a document in the two samples (and other unclassified documents) to be classified correctly in one and only one document class. A sample of 2,897 documents from the TIPSTER collection was used to investigate this problem. This problem was divided into the following four subproblems. The first subproblem consists of identifying the set keywords to describe the documents\u27 content. Computational results of twenty experiments suggested that single-word keywords addressed the main problem effectively. The second subproblem requires a methodology to construct classification rules to infer the class of unclassified documents. A logical analysis approach called the One Clause At a Time algorithm (OCAT) is used to address this problem. Its accuracy is compared to the one of the Vector Space Model (VSM), a benchmarking methodology in document classification processes. Under identical experimental conditions, some computational results suggests that the OCAT algorithm is more accurate than the VSM to solve the main problem. The third subproblem consists of providing a methodology to construct better rules as more documents become available. This problem has been investigated using the OCAT algorithm under a guided and a random teaming approach. Computational results on three samples of 510 documents indicate that the guided teaming approach constructs more accurate rules. In the fourth subproblem an incremental version of the OCAT algorithm is required. The algorithm is needed to speed up the construction of the classification rules. Computational results on three samples of 336 documents each show that: (i) the classification rules become accurate more rapidly, (ii) the CPU times are substantially reduced, and ( iii) the rules become more complex as more documents were added to the experiment. In summary, the results of this research suggest with high confidence that the incremental OCAT algorithm can perform better than the VSM and that it can deliver better and faster results for the classification of large collections of documents

The Upper Bound Theorem in forging processes: Model of Triangular Rigid Zones on parts with horizontal symmetry

The analysis to determine the necessary forces with which to achieve a plastic deformation in metallic materials, in particular, in forging processes and under conditions of plain strain, has been raised over the years through a double approach; on the one hand, by analytical methods that involve a great complexity in their developments but that allow a direct understanding of the parameters that direct these processes. On the other hand, numerical methods, in which, thanks to the enormous development of computer technology, they provide solutions with a high approximation but, in most cases, do not allow to interpret independently the effect of each one of the parameters that come into play. The development of computers relegated analytical methods to the background. An alternative of great interest to apply these methods comes from the study of the Upper Bound Theorem by means of the Triangular Rigid Zones (TRZ) Model. One of the main limitations in the application of this model come from the fact that it is necessary to define a kinematically admissible velocity field and for complex geometric configurations of parts, this field becomes increasingly complicated. A new approach has delimited, from a theoretical perspective, a modular configuration based on a General Module formed by three TRZ that adapts to any geometry of flat surfaces of the part. Another limitation of the Upper Bound Method is the consideration of the plain strain represented by a flat section with double symmetry. Obviously, this imposition only allows to study a limited number of part configurations, which restricts its application in forging processes since the great majority of forged parts do not present geometrically this double symmetry. The present work releases one of these boundary conditions allowing to expand the possibilities of application of this method.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Mixing in convective thermal fluxes in unsteady nonhomogeneous flows generating complex three dimensional vorticity patterns

Diffusion and scaling of the velocity and vorticity in a thermoelectric driven heating and cooling experimental device is presented in order to map the different patterns and transitions between two and three dimensional convection in an enclosure with complex driven flows. The size of the water tank is of 0.2 x 0.2 x 0.1 m and the heat sources or sinks can be regulated both in power and sign [1-3]. The thermal convective driven flows are generated by means of Peltier effects in 4 wall extended positions of 0.05 x 0.05 cm each. The parameter range of convective cell array varies strongly with the Topology of the boundary conditions. Side heat and momentum fluxes are a function of Rayleigh, Peclet and Nusselt numbers, [4-6] Visualizations are performed by PIV, Particle tracking and shadowgraph. The structure of the flow is shown by setting up a convective flow generated by buoyant heat fluxes. The experiments described here investigate high Prandtl number mixing using brine and fresh water in order to form a density interface and low Prandtl number mixing with temperature gradients. The evolution of the mixing fronts are compared and the topological characteristics of the merging of the convective structures are examined for different configurations. Based on two dimensional Vorticity spectral analysis, new techniques can be very useful to determine the evolution of scales considering the multi-fractal structure of the convective flows.Peer ReviewedPostprint (published version

RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors

Background: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution. Homozygous mutations of human IGF1 cause syndromic sensorineural deafness, decreased intrauterine and postnatal growth rates, and mental retardation. In the mouse, deficits in IGF-I result in profound hearing loss associated with reduced survival, differentiation and maturation of auditory neurons. Nevertheless, little is known about the molecular basis of IGF-I activity in hearing and deafness. Methodology/Principal Findings: A combination of quantitative RT-PCR, subcellular fractionation and Western blotting, along with in situ hybridization studies show IGF-I and its high affinity receptor to be strongly expressed in the embryonic and postnatal mouse cochlea. The expression of both proteins decreases after birth and in the cochlea of E18.5 embryonic Igf1(-/-) null mice, the balance of the main IGF related signalling pathways is altered, with lower activation of Akt and ERK1/2 and stronger activation of p38 kinase. By comparing the Igf1(-/-) and Igf1(+/+) transcriptomes in E18.5 mouse cochleae using RNA microchips and validating their results, we demonstrate the up-regulation of the FoxM1 transcription factor and the misexpression of the neural progenitor transcription factors Six6 and Mash1 associated with the loss of IGF-I. Parallel, in silico promoter analysis of the genes modulated in conjunction with the loss of IGF-I revealed the possible involvement of MEF2 in cochlear development. E18.5 Igf1(+/+) mouse auditory ganglion neurons showed intense MEF2A and MEF2D nuclear staining and MEF2A was also evident in the organ of Corti. At P15, MEF2A and MEF2D expression were shown in neurons and sensory cells. In the absence of IGF-I, nuclear levels of MEF2 were diminished, indicating less transcriptional MEF2 activity. By contrast, there was an increase in the nuclear accumulation of FoxM1 and a corresponding decrease in the nuclear cyclin-dependent kinase inhibitor p27(Kip1). Conclusions/Significance: We have defined the spatiotemporal expression of elements involved in IGF signalling during inner ear development and reveal novel regulatory mechanisms that are modulated by IGF-I in promoting sensory cell and neural survival and differentiation. These data will help us to understand the molecular bases of human sensorineural deafness associated to deficits in IGF-I

Diagnóstico, análisis y propuesta de un modelo de servicio humanizado para la unidad de urgencias de la Clínica Universidades de La Sabana

El desarrollo del presente trabajo se realizo en la unidad de urgencias de la clínica universidad de la sabana, con el propósito de diagnosticar, analizar y proponer un modelo den servicio humanizado. Con base en la información obtenida a través de fuentes primarias y secundarias, se evidenciaron brechas entre el ser y el deber ser en los procesos de la unidad, las cuales fueron interpretadas en cinco dimensiones de servicio: tangibles, empatía, seguridad, confiabilidad y sensibilidad. De acuerdo a la información obtenida se plantean unas estrategias, un plan de mejoramiento y un modelo de servicio orientado a atender las necesidades de pacientes/usuarios, contribuyendo holísticamente al bienestar del ser humano y a la clínica en el cumplimiento de su proyección estratégica

Failed and successful innovations: The role of geographic proximity and international diversity of partners in technological collaboration

We aim to clarify the role of research partnerships on the success and failure of innovation projects by examining the geographic proximity and diversity of partners. First, we argue that collaboration with geographically near partners will contribute relatively more to innovation success than it does to innovation failure, while collaboration with geographically distant partners will contribute relatively more to innovation failure than it does to innovation success. Second, we postulate that lower levels of international diversity will contribute relatively more to innovation success than it does to innovation failure, while higher levels of international diversity will contribute relatively more to innovation failure than it does to innovation success. Using a large dataset of firms for the period 2008–2013, we perform a joint analysis of failed and successful innovations. Our empirical findings support our theoretical arguments. Our results highlight the relevance of studying both failed and successful innovations and the importance of knowing their determinants to manage the innovation process successfully. Moreover, our findings should alert managers to the importance of geographic location when choosing collaboration partners. It is noteworthy that beyond a certain threshold, international diversity begins to act as a brake on innovation success and to increase the likelihood of failure.This project was funded by the Government Research Agency of Spanish Ministry of Science and Innovation (PID2019-106874GB-I00/AEI/10.13039/501100011033) and Spanish Ministry of Economy and Business (ECO2017-87514-P). All authors have contributed equally to this paper

Vulneración del derecho fundamental al debido proceso por conflicto negativo de competencias, en demandas laborales de única instancia en razón a la cuantía, en el sistema judicial colombiano

Este documento tiene como objetivo general Identificar la principal causa que produce vulneración al derecho fundamental al debido proceso en demandas laborales de única instancia en razón a la cuantía, por conflicto negativo de competencias, en el sistema judicial colombiano. Se asume éste, a partir de la pregunta de investigación: ¿Cual es la principal causa de vulneración al derecho fundamental al debido proceso en demandas laborales de única instancia en razón a la cuantía por conflicto negativo de competencias en el sistema judicial colombiano? Como Itinerario y estructura del trabajo se realiza un recorrido de tres segmentos capitulares. El primero se ocupa del estado del arte del problema, conceptualización y caracterización, se sintetiza el problema a partir de las ideas fuerza sobrevinientes en el desarrollo de tres subapartados del capítulo de tipo conceptual y empírico conduciendo a la ratificación de una hipótesis de valor de acuerdo con orientaciones de Mejía El segundo se ocupa del marco teórico para la solución potencial del problema, su objetivo es acercarse a la síntesis de solución del problema en estudio y al modo como podría validarse la hipótesis propuesta. El tercero establece validación de la hipótesis o conclusiones sustantivas resumiendo e ilustrando la hipótesis, luego haciendo sus proyecciones conceptuales y empíricas mediante la aplicación de las matrices categoriales, y la matriz relacional, propuestas desde la metodología cualitativa hermenéutica y finalmente se expresan las conclusiones y sugerencias que aplican para este documento. Entre las que destaca como principal causa de esta vulneración la ausencia de un criterio unificado para resolver el conflicto negativo de competencias por colisión de normatividad y ocasionalmente por ignorancia de la misma.Abstract. This document has the general objective Identify the main cause that produces violation of the fundamental right to due process in labor demands single instance due to the amount by negative conflict of jurisdiction, in the Colombian judicial system. it is assumed, from the research question: What is the main cause of violation of the fundamental right to due process in labor demands single instance due to the amount by negative conflict of jurisdiction in the Colombian judicial system? As itinerary and structure of work a route segments Chapter three is performed. The first deals with the state of the art of the problem, conceptualization and characterization, the problem is synthesized from the ideas supervening force in the development of three sub-sections of Chapter conceptual and empirical leading to the ratification of a hypothesis value according with guidance Mejia the second deals with the theoretical framework for the potential solution of the problem, your goal is to approach the synthesis of solving the problem under study and the way the proposed hypothesis could be validated. The third set validation of the hypothesis or substantive conclusions summarizing and illustrating the hypothesis, then making its conceptual and empirical projections by applying the categorical matrices, and the relational matrix, proposals from the qualitative methodology hermeneutics and finally the conclusions and suggestions expressed applying to this document. Among which it stands out as the main cause of this breach the absence of a unified approach to resolve the conflict of jurisdiction negative collision of norms and occasionally by ignorance of the same criteria.Maestrí