183 research outputs found
Monitorización biométrica en tiempo real con dispositivo móvil y plataforma de análisis de datos
En este proyecto se va a crear un sistema autónomo capaz de monitorizar parámetros vitales de un usuario en
tiempo real, detectando situaciones críticas y actuando de forma inmediata mediante el envío de notificaciones
al usuario afectado. Para ello, se hace uso de un dispositivo holter inalámbrico situado en el tórax, un
dispositivo móvil y una plataforma de análisis de datos.
Además, el sistema es capaz de convertir los datos, tomados por el holter, a un formato estandarizado, para que
los profesionales médicos puedan acceder a ellos desde sus equipos.
Durante su desarrollo, se han tenido en cuenta aspectos como la seguridad de los datos y la escalabilidad del
sistema, con la idea de poder ser aplicado a casos de uso reales.The aim of this project is the development of an autonomous system capable of monitoring, in real time, vital
parameters of the user, detecting critical situations and acting immediately by sending notifications to the
affected user. To do this, the system uses a wireless holter monitor located on the thorax of the user, a mobile
device and a data analytics platform.
In addition, the system converts the data collected by the holter monitor to a standard format, in order to allow
medical professionals to access them using their medical equipments.
During all the development, some aspects like data security and scalability have been considered with the
purpose of being used in real cases.Universidad de Sevilla. Grado en Ingeniería de las Tecnologías de Telecomunicació
Autopercepción de inteligencia contextual para jugar y de competencia decisional en el fútbol = Game intelligence and perceived competence to decide on soccer players
En el presente estudio se analizó la autopercepción de competencia decisional y la inteligencia contextual de jugadores de fútbol de diferente nivel de pericia. Además, se exploraron las relaciones existentes entre las autopercepciones de competencia para decidir y de inteligencia contextual en jugadores de fútbol, para lo cual participaron voluntariamente 467 jugadores (M = 20,26, DT = 4,83). El nivel de pericia de los participantes se estableció en tres diferentes: Autonómico (N = 141), nacional (N = 253) e internacional (N = 73), de un total de 46 clubes españoles así como de varias selecciones nacionales. Se utilizaron dos instrumentos en forma de cuestionarios. El primero fue el Cuestionario de Inteligencia Contextual Percibida en el Deporte (ICD) y el segundo el de Estilos de Toma de Decisión en el Deporte (CETD). Los resultados mostraron que la competencia decisional y la inteligencia contextual están relacionadas y mejoran según aumenta el nivel deportivo. ----------ABSTRACT---------- The aim of this paper was to analyze decisional competence and contextual intelligence in sport among different level of expertise football players. In addition, the relationship between self-perceptions of decisional competence and contextual intelligence was assessed. Participants were 467 football players (M=20,26, DT=5,43). They were assigned three levels of expertise: Autonomic (N = 141), National (N = 253) and International (N = 73), from a group of 46 spanish clubs and several national teams. The Contextual Intelligence in Sport Questionnaire (ICD) and the Decision Making in Sport Questionnaire (CETD) were used to explore self-perceptions of players. Results showed that self-perceptions of Contextual Intelligence and Decision Making increased with the level of expertise
Inteligencia contextual y pericia en el fútbol
Para los entrenadores la inteligencia en el juego es uno de los intangibles que predicen el éxito en la competición. De ahí que el objetivo de este estudio fuera analizar la percepción que jugadores de fútbol de diferente nivel de pericia tenían de su inteligencia para el juego. Se aplicó el Cuestionario de Inteligencia Contextual en el Deporte (ICD) que evalúa tres dimensiones: Inteligencia Anticipatoria, Inteligencia Táctica e Inteligencia Competitiva. En este estudio participaron 690 jugadores de fútbol de diferente nivel competitivo. Los resultados mostrarion que a medida que aumentaba el nivel competitivo se incrementaba la percepción de los jugadores sobre su inteligencia contextual. Este estudio confirma el papel que para los jugadores posee el sentirse 308 competentes para solucionar los problemas tácticos de su deporte y que este sentimiento aumenta con su nivel de competencia
Self perception of decision making competence in spanish football players
Background: It is known that competence to make decisions is a fundamental aspect of sport competition. Objective: This study has analyzed the decision profile of a sample of Spanish football players of different levels of expertise. Methods: 690 Spanish football players of national and international level completed the decision making questionnaire, which cover three dimensions ? perceived decision competence, decision anxiety and commitment with decision learning. MANCOVA and ANOVA analysis were carried out to analyse the differences in each dimension based on the level of expertise. Results: Results showed that perception of decision making competence increased and the anxiety decreased with the level of expertise. Conclusions: This study confirmed the usefulness of this questionnaire in the process of training for coaches and sport psychologists
Profiles of University Professors in Spain for the European Higher Education Area (EHEA)
This paper presents the findings of a research study of professors’ profiles for the European Higher Education Area (EHEA) conducted in five spanish universities. Through the application of qualitative methods of inquiry, the perceptions of several groups of university professors over the principal teaching qualifications necessary for the coordination of higher education throughout the European Union have been obtained. Data analysis indicates a significant discrepancy between actual Spanish professors and those required by EHEA. It has also made possible the detailed description of teaching competency profiles that professors believe to be fundamental for the new functions demanded of them in the present changing social and educational situation
University education at present times: teachers' profiles and teaching competencies required
La creación del Espacio Europeo de Educación Superior trae consigo una serie de cambios en la docencia universitaria, y por tanto en la actuación del profesorado. En este trabajo nos hemos planteado conocer la adecuación y relevancia de distintos perfiles docentes de cara a afrontar la docencia en el marco del EEES, e identificar las competencias más relevantes y útiles para el desempeño del profesorado universitario en este nuevo marco de referencia. Hemos partido de 4 perfiles y 87 competencias identificados en una fase previa de nuestra investigación. Un total de 61 profesores expertos, pertenecientes a cinco universidades españolas, han expresado sus valoraciones a través de un cuestionario diseñado para tal fin. De acuerdo con los resultados obtenidos, los perfiles que hemos denominado “profesor multifunción”, “especialista en docencia” y “docente investigador” son los más valorados. Las competencias docentes más valoradas son las que se encuadran en la planificación de la docencia, desarrollo de la docencia y la evaluación, dándose menos importancia a las relacionadas con la tutoría del alumnado, la gestión y la propia formación continua.Getting started the European Higher Education Area (EHEA); it brings about the need to implement some changes in university teachers teaching procedures. This paper presents some findings of a research study aimed firstly to stimate the suitability and importance for teaching in the EHEA of some teacher’s profiles; secondly we looked for the identification of core teaching competencies in that mentioned education context. In a previous research stage, 4 teachers’ profiles and 87 main teaching competencies have been identified; now we present the assessment of 61 senior professors (‘teaching experts’ – members of 5 spanish universities) about that profiles and competencies then identified; their opinions have been obtained through an on-line questionnaire. Research findings show three more valued teachers profiles, laveled as “multifunction teacher”, “teaching expert” and “research teacher”. Among the more valueted teaching competencies we find the competerncies for planning, implement and evaluate students learning; tutoring studentes and menagement competencies, as well as in-service teachers trainingcompetencies have not got such a high assessment scores
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
A missense change in RRAS2 (Gln to Leu), analogous to the Gln-to-Leu mutation of RAS oncoproteins, has been identified as a long-tail hotspot mutation in cancer and Noonan syndrome. However, the relevance of this mutation for in vivo tumorigenesis remains understudied. Here we show, using an inducible knockin mouse model, that R-Ras2 triggers rapid development of a wide spectrum of tumors when somatically expressed in adult tissues. These tumors show limited overlap with those originated by classical Ras oncogenes. R-Ras2-driven tumors can be classified into different subtypes according to therapeutic susceptibility. Importantly, the most relevant R-Ras2-driven tumors are dependent on mTORC1 but independent of phosphatidylinositol 3-kinase-, MEK-, and Ral guanosine diphosphate (GDP) dissociation stimulator. This pharmacological vulnerability is due to the extensive rewiring by R-Ras2 of pathways that orthogonally stimulate mTORC1 signaling. These findings demonstrate that RRAS2 is a bona fide oncogenic driver and unveil therapeutic strategies for patients with cancer and Noonan syndrome bearing RRAS2 mutations.We thank M. Blázquez and the personnel of the CIC Flow Cytometry, Microscopy, Pathology, and Genomics Units for expert technical work. X.R.B.’s project leading to these results has received funding from the Spanish Association against Cancer (GC16173472GARC), the Castilla-León government (CSI252P18, CSI145P20, and CLC-2017-01), the RTI2018-096481-B-100 grant cofounded by MCIN/AEI/10.13039/501100011033 and the European Research Development Fund “A way of making Europe” of the European Union, and “la Caixa” Banking Foundation (HR20-00164). X.R.B.’s institution is supported by the Programa de Apoyo a Planes Estratégicos de Investigación de Estructuras de Investigación de Excelencia of the Castilla-León government (CLC-2017-01). J.R.-V. received funding from the Carlos III Health Institute (PI20/01724). J.R.-V.’s contract is supported by a senior postdoctoral contract of the Spanish Association against Cancer. L.C.’s contract was supported by contracts from the Spanish Association against Cancer and the CLC-2017-01 grant. L.F.L.-M.’s contract was mostly supported by funding from the Spanish Ministry of Education, Culture and Sports (FPU13/02923) and, subsequently, by the CLC-2017-01 grant. R.C. was supported by a predoctoral contract from the MSI (BES-2016-0077909) and the CLC-2017-01 grant
Finding immunological differences to help diagnosis and early treatment of Kawasaki Disease and MIS-C (Multisystem Inflammatory Syndrome in Children)
Resumen del trabajo presentado en el 43 Congreso De La Sociedad Española de Inmunología, celebrado en León (España) del 22 al 24 de septiembre de 2022.The recent COVID-19 pandemic was first thought to spare children from health deprivation caused by infection with SARS-CoV-2. However, soon a new syndrome resembling Kawasaki Disease (KD) was reported: Multisystem Inflammatory Syndrome in Children (MIS-C). The aim of this study is to provide new biomarkers for both diseases in order to facilitate diagnosis and reduce the time-lapse until treatment is provided – which will reduce the risk of developing severe cardiovascular complications. An extensive immune system characterization by flow cytometry and serum protein characterization by a multiplex technology (Olink) was performed from fresh blood samples of patients with acute MIS-C (n=19) and KD (n=10). For protein characterization we also analysed recovery samples for these groups (n=19 and n=8, respectively). Besides the already described lymphopenia in MIS-C, we found additional significant immune differences in both groups. Although lymphocyte numbers (cells/ml) were lower in MIS-C, percentages of activated T-CD4+ and T-CD8+ cells were higher compared to KD. Moreover, when comparing activated T cells in MIS-C and KD individually, regulatory T cells (Treg) showed the highest levels. These data suggest a stronger response of T cells in MIS-C, and higher Treg activity in both groups, which could reflect the response to the excessive inflammation. Ratios previously described in other inflammatory conditions were evaluated: MIS-C showed higher neutrophil/lymphocyte and Th17/Treg ratios than KD, suggesting higher inflammatory conditions in this group. In addition, monocyte and dendritic cells (DCs) numbers were decreased in MIS-C relative to KD. Parallel to these inflammatory cellular profiles, we identified increased levels of inflammatory cytokines in plasma of patients during the acute phase of the disease compared to recovery samples. Moreover, IL-6, which is one of the main cytokines involved in cytokine storm in adult COVID-19, was higher in MIS-C suggesting, again, stronger inflammatory conditions in this pathology compared to KD
Association of Rhinitis With Asthma Prevalence and Severity
Multicenter study[Abstract] Asthma and rhinitis often co-exist in the same patient. Although some authors observed a higher prevalence and/or greater severity of asthma in patients with rhinitis, this view is not homogeneous and the debate continues. The aim of our study is to describe the prevalence of rhinitis in children and adolescents and to analyse their relationship with the prevalence of asthma. A multicentre study was conducted using the methodology of the International Study of Asthma and Allergies in Childhood (ISAAC). The target population of the study was all those school children aged 6-7 and 13-14 years from 6 of the main health catchment areas of Galicia (1.9 million inhabitants). The schools required were randomly selected, and all children in the targeted age ranges were included. Multiple logistic regression was used to obtain adjusted prevalence odds ratios (OR) between asthma symptoms of the schoolchildren and rhinitis prevalence. The results were adjusted for parental smoking habits, maternal education level, cat and dog exposure, and obesity. A total of 21,420 valid questionnaires were finally obtained. Rhinitis was associated with a significant increase in the prevalence of asthma in both age groups. The highest OR were 11.375 for exercise induced asthma (EIA) for children with recent rhinoconjunctivitis and 9.807 for children with recent rhinitis in 6-7 years old group. The prevalence OR's are higher in EIA and severe asthmatics. Rhinitis in children and adolescents is associated with a higher prevalence and severity of asthma.This work was funded by the Maria Jose Jove Foundatio
Implantación de un sistema integral de gestión del conocimiento para los procesos de innovación docente de la Universidad de Salamanca
Memoria ID-0312. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015
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