Fate of pharmaceuticals and PFASs during the electrochemical generation of a nitrogen-rich nutrient product from real reject water

Recycling vital macronutrients, such as nitrogen, from wastewaters back to fertiliser use is becoming essential to ensure sustainable agricultural practices. Technologies developed for such purposes are typically evaluated for their capacity to recover nutrients; however, the presence of contaminants of emerging concern (CECs) in these waste-derived nutrient products must not be overlooked. In this study, nitrogen was recovered from real anaerobically digested municipal sewage sludge reject water using a novel set-up combining membrane-based electroconcentration (EC) with electrochemical advanced oxidation processes (EAOPs). Simultaneously, the fate of five spiked pharmaceuticals (carbamazepine, ciprofloxacin, diclofenac, erythromycin and metoprolol) as well as ten indigenous perfluoroalkyl substances (PFASs) was investigated. The EC-EAOP system was effective in up-concentrating nitrogen ca. 13 times to a final concentration of 12.7 ± 0.8 g L−1 in the nutrient product. At the same time, no up-concentration was observed for the pharmaceuticals and their concentrations in the recovered concentrated remained at ≤ 3.4 ± 1.3 µg L−1. The EAOPs were the main transformation mechanism for all the pharmaceuticals at 33–88% efficiency, while diclofenac also notably adsorbed in the system (30 ± 1.4%). Out of the ten studied PFASs, only three were found in the recovered nutrient concentrate, albeit at very limited concentrations of ≤ 0.024 ± 0.013 µg L−1. The EAOPs were found to degrade longer-chain PFASs into their shorter-chain counterparts. The low contaminant concentrations in the nutrient product pose a reduced risk for soil contamination compared to, e.g., biosolids that are more typically used as fertilisers.publishedVersionPeer reviewe

Experimental investigation and modelling of the transformation of illicit drugs in a pilot-scale sewer system

In-sewer stability of illicit drug biomarkers has been evaluated by several reactor-based studies but less has been done in sewer pipes. Experiments conducted in sewer pipes have advantages over lab-scale reactors in providing more realistic biomarker stability due to the flow and biological dynamics. This study assessed the transportation and transformation of seven illicit drug biomarker compounds in a pilot-scale rising main and a gravity sewer pipe. Biomarkers presented diverse stability patterns in the pilot sewers, based on which a drug transformation model was calibrated. This model was subsequently validated using transformation datasets from literature, aiming to demonstrate the predictability of the pilot-based transformation coefficients under varying sewer conditions. Furthermore, transformation coefficients for five investigated biomarkers were generated from four studies and their prediction capabilities under the pilot sewer conditions were jointly assessed using performance statistics. The transformation model was successful in simulating the in-sewer stability for most illicit drugs. However, further study is required to delineate the sources and pathways for those compounds with potential formations to be simulated in the transformation model. Overall, the transformation model calibrated using the pilot-sewer data is a credible tool for the application of wastewater-based epidemiology

Systematic evaluation of biomarker stability in pilot scale sewer pipes

Transformation of biomarkers (or their stability) during sewer transport is an important issue for wastewater-based epidemiology (WBE). Most studies so far have been conducted in the laboratory, which usually employed unrealistic conditions. In the present study, we utilized a pilot sewer system including a gravity pipe and a rising main pipe to investigate the fate of 24 pharmaceutical biomarkers. A programmable logic controller was used to control and monitor the system including sewer operational conditions and wastewater properties. Sequential samples were collected that can represent hydraulic retention time (HRT) of up to 8 h in a rising main and 4 h in a gravity sewer. Wastewater parameters and biomarker concentrations were analysed to evaluate the stability and transformation kinetics. The wastewater parameters of the pilot system were close to the conditions of real sewers. The findings of biomarker transformation were also close to real sewer data with seventeen biomarkers reported as stable while buprenorphine, caffeine, ethyl-sulfate, methadone, paracetamol, paraxanthine and salicylic acid degraded to variable extents. Both zero-order and first-order kinetics were used to model the degradation of unstable biomarkers and interestingly the goodness of fit R for the zero-order model was higher than the first-order model for all unstable biomarkers in the rising main. The pilot sewer system simulates more realistic conditions than benchtop laboratory setups and may provide a more accurate approach for assessing the in-sewer transformation kinetics and stability of biomarkers

Experimental Investigation and Modeling of the Transformation of Illicit Drugs in a Pilot-Scale Sewer System

In-sewer stability of illicit drug biomarkers has been evaluated by several reactor-based studies, but less has beendone in sewer pipes. Experiments conducted in sewer pipes have advantages over lab-scale reactors in providing more realisticbiomarker stability due to theflow and biological dynamics. This study assessed the transportation and transformation of sevenillicit drug biomarker compounds in a pilot-scale rising main and a gravity sewer pipe. Biomarkers presented diverse stabilitypatterns in the pilot sewers, based on which a drug transformation model was calibrated. This model was subsequently validatedusing transformation data sets from the literature, aiming to demonstrate the predictability of the pilot-based transformationcoefficients under varying sewer conditions. Furthermore, transformation coefficients forfive investigated biomarkers weregenerated from four studies, and their prediction capabilities under the pilot-sewer conditions were jointly assessed usingperformance statistics. The transformation model was successful in simulating the in-sewer stability for most illicit drugs.However, further study is required to delineate the sources and pathways for those compounds with potential formations to besimulated in the transformation model. Overall, the transformation model calibrated using the pilot-sewer data is a credible toolfor the application of wastewater-based epidemiology