1,711 research outputs found
The Demand Side Determinate of NFL Ticket Prices
We study the demand-side determinants of average NFL ticket prices using a panel model for the years 2010 to 2013. We estimate the average ticket price as a function of income, population, the housing price index, winning percentage from the previous season, and other professional sports teams in the metropolitan area of each team. Our results indicate that income has the largest effect on the average NFL ticket price. The number of other professional sports teams was found to have the smallest effect in the average NFL ticket price
Out-of-plane magnetic domain structure in a thin film of La0.67Sr0.33MnO3 on SrTiO3 (001) observed by magnetic force microscopy
The room temperature out-of-plane magnetization of epitaxial thin films of La0.67Sr0.33MnO3 on SrTiO3 (001) has been investigated with magnetic force microscopy, using magnetic tips with very small coercivity, relative to the film. A clear magnetic pattern in the form of a checkerboard, with domain dimensions of a few hundred nanometers, was found for the thin, coherently strained films, which is approximately aligned along the maximum strain [110] and [1[overline 1]0] directions in the film. With increasing in-plane applied magnetic field, the magnetic contrast reduces, reflecting the rotation of the magnetization vector into the plane of the film. This process is reversible with the field. The out-of-plane magnetic pattern is not sensitive to rotation of the in-plane field. We attribute the observed out-of-plane magnetization component to an out-of-plane magnetic anisotropy, which is a remainder of the [111] magnetic easy axis in bulk La0.67Sr0.33MnO3 single crystal
Assessing TMS-induced D and I waves with spinal H-reflexes
Transcranial magnetic stimulation (TMS) of motor cortex produces a series of descending volleys known as D (direct) and I (indirect) waves. In the present study, we questioned whether spinal H-reflexes can be used to dissect D waves and early and late I waves from TMS. We therefore probed H-reflex facilitation at arrival times of D and I waves at the spinal level and thereby changed TMS parameters that have previously been shown to have selective effects on evoked D and different I waves. We changed TMS intensity and current direction and applied a double-pulse paradigm known as short-interval intracortical inhibition (SICI). Experiments were conducted in flexor carpi radialis (FCR) in the arm and soleus (SOL) in the leg. There were two major findings: 1) in FCR, H-reflex facilitation showed characteristic modulations with altered TMS parameters that correspond to the changes of evoked D and I waves; and 2) H-reflexes in SOL did not, possibly because of increased interference from other spinal circuits. Therefore, the most significant outcome of this study is that in FCR, H-reflexes combined with TMS seem to be a useful technique to dissect TMS-induced D and I waves. NEW & NOTEWORTHY Questions that relate to corticospinal function in pathophysiology and movement control demand sophisticated techniques to provide information about corticospinal mechanisms. We introduce a noninvasive electrophysiological technique that may be useful in describing such mechanisms in more detail by dissecting D and I waves from transcranial magnetic stimulation (TMS). Based on the combination of spinal H-reflexes and TMS in the flexor carpi radialis muscle, the technique was shown to measure selective effects on D and I waves from changing TMS parameters
Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission
Journal ArticleCopyright © 2013 European Molecular Biology OrganizationMitochondria and peroxisomes can be fragmented by the process of fission. The fission machineries of both organelles share a set of proteins. GDAP1 is a tail-anchored protein of mitochondria and induces mitochondrial fragmentation. Mutations in GDAP1 lead to Charcot-Marie-Tooth disease (CMT), an inherited peripheral neuropathy, and affect mitochondrial dynamics. Here, we show that GDAP1 is also targeted to peroxisomes mediated by the import receptor Pex19. Knockdown of GDAP1 leads to peroxisomal elongation that can be rescued by re-expressing GDAP1 and by missense mutated forms found in CMT patients. GDAP1-induced peroxisomal fission is dependent on the integrity of its hydrophobic domain 1, and on Drp1 and Mff, as is mitochondrial fission. Thus, GDAP1 regulates mitochondrial and peroxisomal fission by a similar mechanism. However, our results reveal also a more critical role of the amino-terminal GDAP1 domains, carrying most CMT-causing mutations, in the regulation of mitochondrial compared to peroxisomal fission. © 2013 European Molecular Biology Organization.Swiss National Science FoundationNational Center for Competence in Research (NCCR)BBSRCPortuguese Foundation for Science and Technology (FCT)Fundo Europeu De Desenvolvimento Regional (FEDER
Systems, methods, and apparatus of a low conductance silicon micro-leak for mass spectrometer inlet
Systems, methods and apparatus are provided through which in some embodiments a mass spectrometer micro-leak includes a number of channels fabricated by semiconductor processing tools and that includes a number of inlet holes that provide access to the channels
Systems, Methods, and Apparatus of a Low Conductance Silicon Micro-Leak for Mass Spectrometer Inlet
Systems, methods and apparatus are provided through which in some embodiments a mass spectrometer micro-leak includes a number of channels fabricated by semiconductor processing tools and that includes a number of inlet holes that provide access to the channels
Superconductivity in an Einstein Solid AxV2Al20 (A = Al and Ga)
A cage compound AxV2Al20 (Al10V), that was called an Einstein solid by Caplin
and coworkers 40 years ago, is revisited to investigate the low-energy, local
vibrations of the A atoms and their influence on the electronic and
superconducting properties of the compound. Polycrystalline samples with A =
Al, Ga, Y, and La are studied through resistivity and heat capacity
measurements. Weak-coupling BCS superconductivity is observed below Tc = 1.49,
1.66, and 0.69 K for Ax = Al0.3, Ga0.2, and Y, respectively, but not above 0.4
K for Ax = La. Low-energy modes are detected only for A = Al and Ga, which are
approximately described by the Einstein model with Einstein temperatures of 24
and 8 K, respectively. A weak but significant coupling between the low-energy
modes, which are almost identical to those called rattling in recent study, and
conduction electrons manifests itself as anomalous enhancement in resistivity
at around low temperatures corresponding to the Einstein temperatures.Comment: 12 pages, 5 figures, to be published in J. Phys. Soc. Jp
Evaluation of cardiovascular effects of intramuscular medetomidine and a medetomidine–vatinoxan combination in Beagle dogs: A randomized blinded crossover laboratory study
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