Second-order QCD corrections to event shape distributions in deep inelastic scattering

We compute the next-to-next-to-leading order (NNLO) QCD corrections to event shape distributions and their mean values in deep inelastic lepton–nucleon scattering. The magnitude and shape of the corrections varies considerably between different variables. The corrections reduce the renormalization and factorization scale uncertainty of the predictions. Using a dispersive model to describe non-perturbative power corrections, we compare the NNLO QCD predictions with data from the H1 and ZEUS experiments. The newly derived corrections improve the theory description of the distributions and of their mean values

NNLO QCD corrections to event orientation in e+e- annihilation

We present a new implementation of the NNLO QCD corrections to three-jet final states and related event-shape observables in electron–positron annihilation. Our implementation is based on the antenna subtraction method, and is performed in the NNLOjet framework. The calculation improves upon earlier results by taking into account the full kinematical information on the initial state momenta, thereby allowing the event orientation to be computed to NNLO accuracy. We find the event-orientation distributions at LEP and SLC to be very robust under higher order QCD corrections

Induction maintenance concept for HAART as initial treatment in HIV infected infants

<p>Abstract</p> <p>Background</p> <p>Early initiated antiretroviral therapy (ART) in HIV infected infants leads to improved long-term viral suppression and survival. Guidelines recommend initiating therapy with a triple ART consisting of two nucleoside reverse transcriptase inhibitors (NRTIs) and either one additional non-nucleoside reverse transcriptase inhibitor (NNRTI) or a protease inhibitor (PI). Compared to older children and adults, viral relapse is seen more frequently in infants receiving triple ART. We now address the possibility of a more potent ART with a quadruple induction and triple maintenance therapy.</p> <p>Methods</p> <p>We examine the longitudinal course in four HIV infected infants, who were referred from other centers and could not be recruited to multicentre trials. We introduced ART initially consisting of two NRTIs, one NNRTI and one PI and later discontinued the PI at the age of 12 months maintaining a triple regime consisting of two NRTIs and one NNRTI.</p> <p>Results</p> <p>Provided that therapy adherence was maintained we observed an effective sustained decline of viral load and significant CD4 cell reconstitution even after switching to a triple regime. No drug associated toxicity was seen.</p> <p>Conclusion</p> <p>We suggest that a four drug therapy might be a possible initial therapy option in HIV infected infants, at least in those with a high viral load, followed by a maintenance triple regime after 12 months of therapy.</p

Calculations for deep inelastic scattering using fast interpolation grid techniques at NNLO in QCD and the extraction of αs from HERA data

The extension of interpolation-grid frameworks for perturbative QCD calculations at next-to-next-to-leading order (NNLO) is presented for deep inelastic scattering (DIS) processes. A fast and flexible evaluation of higher-order predictions for any a posteriori choice of parton distribution functions (PDFs) or value of the strong coupling constant is essential in iterative fitting procedures to extract PDFs and Standard Model parameters as well as for a detailed study of the scale dependence. The APPLfast project, described here, provides a generic interface between the parton-level Monte Carlo program NNLOjet and both the APPLgrid and fastNLO libraries for the production of interpolation grids at NNLO accuracy. Details of the interface for DIS processes are presented together with the required interpolation grids at NNLO, which are made available. They cover numerous inclusive jet measurements by the H1 and ZEUS experiments at HERA. An extraction of the strong coupling constant is performed as an application of the use of such grids and a best-fit value of αs(MZ)=0.1170(15)exp(25)th is obtained using the HERA inclusive jet cross section data

Erratum to: Calculations for deep inelastic scattering using fast interpolation grid techniques at NNLO in QCD and the extraction of αs\alpha _{\mathrm {s}} from HERA data

The implementation of interpolation grid techniques at NNLO and their subsequent application to the extraction of the strong coupling constant α s αs presented in Ref. [1] are based on the calculation in the framework [2,3,4]. An implementation error was found in this calculation [4] that altered the predicted cross sections for the DIS process at NNLO. While technical aspects and equations remain unchanged, reported numerical values and the extracted value of α s αs are affected. Updated figures, tables, and numbers quoted in the main text that have changed are provided. Numbering of sections and figures is as in Ref. [1]