338 research outputs found

    Controlling an Invasive Forest Pest, the Asiatic Oak Weevil (cyrtepistomus castaneus), Using Prescribed Fire

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    Invasive species are non-native species whose presence is already or is likely to cause harm to the local ecosystem or economy, or human, animal, and plant health (Beck et al, 2006, p.415). The invasive Asiatic oak weevil is the primary leaf-feeding insect on oak trees in the Missouri Ozarks with larvae feeding on the roots of trees and the adults on the leaves (Marquis and Bhatti-Catano, 2017). The goal of this study was to determine if prescribed burns lower the abundance of adult and larval weevils. Eight pairs of 200 m x 200 m plots in the oak-hickory forest at the Tyson Research Station near Eureka, MO were used for the experimental environment. One of each plot pairs were surface-burned in early Spring 2018. In June 2018, mesh emergence traps with jars secured on top were placed under four white and four black oak trees on each plot. From late June-August 2018 the weevils were counted as they emerged and analyzed to determine effects of the sampling date, tree species, aspect, slope, weight, and ultimately weevil density in burned versus unburned plots. Notable differences in the density of weevils on burned vs. unburned plots were observed in favor of the hypothesis. These findings support the need for prescribed fire in the management of Missouri’s forests. References Beck, G. K. Zimmerman, J.D. Schardt, J. Stone, R.R. Lukens, S. Reichard, J. Randall, A.A. Cangelosi, D. Cooper, and J.P. Thompson. 2006. Invasive Species Defined in a Policy Context: Recommendations from the Federal Invasive Species Advisory Committee. Invasive Plant Science and Management 1(4):414-421. Marquis, R. J., & Bhatti-Catano, L. (2017). Impacts of the Asiatic oak weevil (Cyrtepistomus castaneus) on the growth and survivorship of black oak (Quercus velutina) seedlings. Retrieved February 10, 2019, from https://tyson.wustl.edu/allprojects/2017/10/4/impacts of-the-asiatic-oak-weevil-icyrtepistomus-castaneusi-on-the-growth-and-survivorship-of black-oak-iquercus-velutinai-seedling

    Bilder von Armut und Reichtum im Umsonstladen Hamburg

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    So unterschiedlich die Menschen sind, die einen Umsonstladen besuchen oder dort arbeiten, so unterschiedlich sind auch ihre persönlichen Definitionen von Armut und Reichtum. Welche Bilder von Armut und Reichtum lassen sich an einem Ort generieren, an dem gleichzeitig Konsumkritik und (eine andere Art von) Konsum stattfindet?

    Bilder von Armut und Reichtum im Umsonstladen Hamburg

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    So unterschiedlich die Menschen sind, die einen Umsonstladen besuchen oder dort arbeiten, so unterschiedlich sind auch ihre persönlichen Definitionen von Armut und Reichtum. Welche Bilder von Armut und Reichtum lassen sich an einem Ort generieren, an dem gleichzeitig Konsumkritik und (eine andere Art von) Konsum stattfindet?

    Identifying predictive features of autism spectrum disorders in a clinical sample of adolescents and adults using machine learning

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    Diagnosing autism spectrum disorders (ASD) is a complicated, time-consuming process which is particularly challenging in older individuals. One of the most widely used behavioral diagnostic tools is the Autism Diagnostic Observation Schedule (ADOS). Previous work using machine learning techniques suggested that ASD detection in children can be achieved with substantially fewer items than the original ADOS. Here, we expand on this work with a specific focus on adolescents and adults as assessed with the ADOS Module 4. We used a machine learning algorithm (support vector machine) to examine whether ASD detection can be improved by identifying a subset of behavioral features from the ADOS Module 4 in a routine clinical sample of N = 673 high-functioning adolescents and adults with ASD (n = 385) and individuals with suspected ASD but other best-estimate or no psychiatric diagnoses (n = 288). We identified reduced subsets of 5 behavioral features for the whole sample as well as age subgroups (adolescents vs. adults) that showed good specificity and sensitivity and reached performance close to that of the existing ADOS algorithm and the full ADOS, with no significant differences in overall performance. These results may help to improve the complicated diagnostic process of ASD by encouraging future efforts to develop novel diagnostic instruments for ASD detection based on the identified constructs as well as aiding clinicians in the difficult question of differential diagnosis

    Reduced pain perception in children and adolescents with ADHD is normalized by methylphenidate

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    Background: The present study examined pain perception in children and adolescents with ADHD and the interaction between pain perception and the administration of methylphenidate (MPH) in order to generate hypotheses for further research that will help to clarify the association between ADHD diagnosis, MPH treatment and pain perception. Methods: We included 260 children and adolescents of the “German Health Interview and Examination Survey for Children and Adolescents” (KiGGS) and analyzed parent’s assessments of children’s pain distribution and pain perception, as well as the influence of MPH administration on pain perception in affected children and adolescents. Results: Pain perception was associated with ADHD and MPH administration, indicating that children and adolescents suffering from ADHD without MPH treatment were reported to have lower pain perception compared to both, healthy controls (HC) and ADHD patients medicated with MPH. Conclusion: We suggest that reduced pain perception in children and adolescents with ADHD not medicated with MPH may lead to higher risk tolerance by misjudgments of dangerous situations, expanding the importance of MPH administration in affected children and adolescents

    Adverse Childhood Experiences and Pregnancy Intentions among Pregnant Women Seeking Prenatal Care

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    BackgroundThis study examined whether adverse childhood experiences (ACEs) are associated with increased risk of having an unwanted or mistimed pregnancy.MethodsWomen in two medical centers within an integrated health system were screened for ACEs during standard prenatal care (N = 745). Multinomial multivariable logistic regression analyses examined the associations of ACEs (count and type) with pregnancy intentions, adjusting for covariates.ResultsOverall, 58.3% of pregnant women reported no ACEs, 19.1% reported one ACE, and 22.7% reported two or more ACEs; 76.2% reported wanting to get pregnant, 18.5% reported wanting to get pregnant but not at this time (i.e., mistimed pregnancy), and 5.2% reported not wanting to get pregnant at all (i.e., unwanted pregnancy). Having two or more (vs. 0) ACEs was associated with higher odds of an unwanted pregnancy (odds ratio, 2.60; 95% confidence interval, 1.19-5.68). Further, childhood loss of parent (odds ratio, 2.20; 95% confidence interval, 1.03-4.71) and neglect (odds ratio, 5.67; 95% confidence interval, 1.72-18.72) were each associated with higher odds of an unwanted pregnancy in separate analyses. ACEs count and type were not significantly associated with having a mistimed pregnancy.ConclusionsAmong women screened for ACEs during standard prenatal care, ACEs were associated with increased odds of having an unwanted pregnancy, but not a mistimed pregnancy. Additional research is needed to better understand the mechanisms through which ACEs and other individual, social, and contextual factors impact pregnancy intentions to better support women and provide appropriate resources to help prevent unintended pregnancies

    8-vinyl-deoxyadenosine, an alternative fluorescent nucleoside analog to 2′-deoxyribosyl-2-aminopurine with improved properties

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    We report here the synthesis and the spectroscopic characterization of 8-vinyl-deoxyadenosine (8vdA), a new fluorescent analog of deoxyadenosine. 8vdA was found to absorb and emit in the same wavelength range as 2′-deoxyribosyl-2-aminopurine (2AP), the most frequently used fluorescent nucleoside analog. Though the quantum yield of 8vdA is similar to that of 2AP, its molar absorption coefficient is about twice, enabling a more sensitive detection. Moreover, the fluorescence of 8vdA was found to be sensitive to temperature and solvent but not to pH (around neutrality) or coupling to phosphate groups. Though 8vdA is base sensitive and susceptible to depurination, the corresponding phosphoramidite was successfully prepared and incorporated in oligonucleotides of the type d(CGT TTT XNX TTT TGC) where N = 8vdA and X = A, T or C. The 8vdA-labeled oligonucleotides gave more stable duplexes than the corresponding 2AP-labeled sequences when X = A or T, indicating that 8vdA is less perturbing than 2AP and probably adopts an anti conformation to preserve the Watson–Crick H-bonding. In addition, the quantum yield of 8vdA is significantly higher than 2AP in all tested oligonucleotides in both their single strand and duplex states. The steady-state and time-resolved fluorescence parameters of 8vdA and 2AP were found to depend similarly on the nature of their flanking residues and on base pairing, suggesting that their photophysics are governed by similar mechanisms. Taken together, our data suggest that 8vdA is a non perturbing nucleoside analog that may be used with improved sensitivity for the same applications as 2AP

    Chlamydia trachomatis prevalence in undocumented migrants undergoing voluntary termination of pregnancy: a prospective cohort study

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    BACKGROUND: Chlamydia trachomatis infection (CTI) is the most frequent sexual transmitted disease (STI) in Switzerland but its prevalence in undocumented migrants is unknown. We aimed to compare CTI prevalence among undocumented migrants undergoing termination of pregnancy (ToP) to the prevalence among women with residency permit. METHODS: This prospective cohort study included all pregnant, undocumented women presenting from March 2005 to October 2006 to the University hospital for ToP. The control group consisted of a systematic sample of pregnant women with legal residency permit coming to the same hospital during the same time period for ToP. RESULTS: One hundred seventy five undocumented women and 208 women with residency permit (controls) were included in the study. Mean ages were 28.0 y (SD 5.5) and 28.2 y (SD 7.5), respectively (p = 0.77). Undocumented women came primarily from Latin-America (78%). Frequently, they lacked contraception (23%, controls 15%, OR 1.8, 95% CI 1.04;2.9). Thirteen percent of undocumented migrants were found to have CTI (compared to 4.4% of controls; OR 3.2, 95% CI 1.4;7.3). CONCLUSION: This population of undocumented, pregnant migrants consisted primarily of young, Latino-American women. Compared to control women, undocumented migrants showed higher prevalence rates of genital CTI, which indicates that health professionals should consider systematic screening for STI in this population. There is a need to design programs providing better access to treatment and education and to increase migrants' awareness of the importance of contraception and transmission of STI

    Pathways to a diagnosis of autism spectrum disorder in Germany: a survey of parents

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    Background: Early identification of autism spectrum disorders (ASD) is a prerequisite for access to early interven‑tions. Although parents often note developmental atypicalities during the first 2 years of life, many children with ASD are not diagnosed until school age. For parents, the long period between first parental concerns and diagnosis is often frustrating and accompanied by uncertainty and worry. Methods: This study retrospectively explored the trajectories of children with a confirmed ASD diagnosis during the diagnostic process, from first parental concerns about their child’s development until the definite diagnosis. A survey concerning the diagnostic process was distributed to parents or legal guardians of children with ASD from three specialized ASD outpatient clinics in Germany. Results: The response rate was 36.9%, and the final sample consisted of carers of 207 affected children (83.6% male, mean age 12.9 years). The children had been diagnosed with childhood autism (55.6%), Asperger syndrome (24.2%), or atypical autism (20.3%). On average, parents had first concerns when their child was 23.4 months old, and an ASD diagnosis was established at a mean age of 78.5 months. Children with atypical autism or Asperger syndrome were diagnosed significantly later (83.9 and 98.1 months, respectively) than children with childhood autism (68.1 months). Children with an IQ < 85 were diagnosed much earlier than those with an IQ ≥ 85. On average, parents visited 3.4 different health professionals (SD=2.4, range 1–20, median: 3.0) until their child received a definite ASD diagnosis. Overall, 38.5% of carers were satisfied with the diagnostic process. Conclusions: In this sample of children with ASD in Germany, the time to diagnosis was higher than in the major‑ity of other comparable studies. These results flag the need for improved forms of service provision and delivery for suspected cases of ASD in Germany
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