L'arte come catalizzatore per la Democrazia del Paesaggio

The project promoted the use of democratic ideals in the process of planning public space in the Nord-Holland district of Kassel, Germany. A public workshop, social gathering and temporary public art installation were the vehicles for empowering marginalized groups and unifying a highly diverse and fragmented community. The emotional map output from the community workshop was the basis for a candle light installation that bisected the neighborhood, engaging the general public on issues that both destabilized and strengthened the community. The engagement of landscape challenges through a site specific art installation offered stakeholders palpable interaction with abstract issues. A cross-disciplinary approach to spatial planning can deepen stakeholder engagement in the just, transparent and inclusive processes of participatory design.Il progetto ha promosso l'uso di ideali democratici nel processo di pianificazione dello spazio pubblico nel quartiere Nord-Holland di Kassel, in Germania. Un seminario pubblico, una raccolta sociale e un'installazione temporanea di arte pubblica sono stati gli strumenti per dare potere ai gruppi emarginati e per riunire una comunità estremamente diversificata e frammentata. Il risultato emotivo del seminario comunitario è stata la base di un'installazione a lume di candela che ha scosso il quartiere, coinvolgendo il pubblico su questioni che hanno destabilizzato e rafforzato la comunità. L'impegno delle sfide del paesaggio attraverso un'installazione artistica specifica per un sito ha offerto ai soggetti interessati un'interazione accettabile con questioni astratte. Un approccio interdisciplinare alla pianificazione territoriale può rafforzare l'impegno delle parti interessate nei processi giusti, trasparenti e inclusivi di progettazione partecipativa

La graciloplastie dynamisée (évaluation de son efficacité dans le traitement de l'incontinence fécale)

NANCY1-SCD Medecine (545472101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Evolution and Predictive Factors of Improvement of Obstructive Sleep Apnea in an Obese Population After Bariatric Surgery

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Assessing of base temperatures and base water potentials for germination of weeds

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Anatomically based comparison of the different transthoracic routes for colon ascension after total esogastrectomy.

International audienceColon interposition is the method of choice to restore the digestive tract after esogastrectomy. The aim of this study was to compare the length of the four available routes for colon transposition (posterior mediastinum route, transpleural route, substernal route and subcutaneous route) and to achieve a specific evaluation of the transpleural route. Our study was conducted with anatomical (dissection) and radiological (2D CT scan reconstructions) protocols. For both, the posterior mediastinum route was always the shortest way and the subcutaneous route was always the longest. For the anatomical results, the transpleural route and the substernal route were similar in terms of length and for the radiological study, the transpleural route was shorter than the substernal route (P < 0.001) and shorter than the subcutaneous route (P < 0.001). We demonstrated that the transpleural route was acceptable for colon transposition in term of length, and could be an alternative when the substernal route is unavailable

Multifactorial Analysis of the Learning Curve for Totally Robotic Roux-en-Y Gastric Bypass for Morbid Obesity

International audienceBackgroundLaparoscopic Roux-en-Y gastric bypass is one of the most commonly performed bariatric operation worldwide for the surgical management of obesity. Totally robotic Roux-en-Y gastric bypass (TR-RYGBP) has been considered to be a better approach by some groups especially early in a surgeon's experience. However, the learning curve associated with TR-RYGBP has been poorly evaluated yet. The aim of this study was to evaluate the learning curve of patients who underwent TR-RYGBP.MethodsThis is a prospective study of 154 first consecutive patients undergoing TR-RYGBP to analyze the influence of surgeon experience, bedside first assistant, and patient factors on operative time and postoperative complications. To give a comprehensive view of success related to the learning process, a single hybrid variable was generated. Multivariate analysis predicted the risk factors for complications and operative time. A risk-adjusted cumulative sum analysis estimated the learning curve.ResultsThe learning curve for TR-RYGBP was 84 cases. Case rank and first assistant level were independent predictors of total operative time. Overall 30-day postoperative morbidity rate was 33.1 % and decreased over time. Surgeon experience (OR 2.6; CI 95 [1.290 to 5.479]; p = 0.0081) and first assistant level (OR 2.42; CI 95 [1.197 to 4.895]; p = 0.0139) remained independent predictors of composite event (operative time and complications).ConclusionsThis study identifed criteria that should be assessed in future studies about TR-RYGBP. Both surgeon experience and bedside first assistant level affected operative duration, but surgeon experience was the most significant factor in reducing complication rates

Are moxifloxacin and levofloxacin equally effective to treat XDR tuberculosis?

International audienceBackground: Moxifloxacin retains partial activity against some fluoroquinolone-resistant mutants of Mycobacterium tuberculosis. Levofloxacin is presumed to be as active as moxifloxacin against drug-susceptible tuberculosis and to have a better safety profile.Objectives: To compare the in vivo activity of levofloxacin and moxifloxacin against M. tuberculosis strains with various levels of fluoroquinolone resistance.Methods: BALB/c mice were intravenously infected with 106M. tuberculosis H37Rv and three isogenic mutants: GyrA A90V, GyrB E540A and GyrB A543V. Treatment with 50 or 100 mg/kg levofloxacin and 60 or 66 mg/kg moxifloxacin was given orally every 6 h, for 4 weeks.Results: Levofloxacin 50 and 100 mg/kg q6h and moxifloxacin 60 and 66 mg/kg q6h generated AUCs in mice equivalent to those of levofloxacin 750 and 1000 mg/day and moxifloxacin 400 and 800 mg/day, respectively, in humans. Moxifloxacin 60 and 66 mg/kg q6h had bactericidal activity against strain H37Rv (MIC ≤ 0.25 mg/L) and mutants GyrB E540A and GyrB A543V (MIC = 0.5 mg/L). Against mutant GyrA A90V (MIC = 2 mg/L), moxifloxacin 60 mg/kg q6h did not prevent bacillary growth, whereas 66 mg/kg q6h had bacteriostatic activity. Levofloxacin 50 mg/kg q6h had bactericidal activity against H37Rv (MIC ≤ 0.25 mg/L) but not against the mutant strains. Levofloxacin 100 mg/kg q6h had bactericidal activity against H37Rv and mutants GyrB E540A (MIC = 0.5 mg/L) and GyrB A543V (MIC= 1 mg/L) but not against mutant GyrA A90V (MIC = 4 mg/L).Conclusions: All mutations reduced fluoroquinolone activity, even those classified as susceptible according to phenotypic tests. High-dose levofloxacin is less effective than high-dose moxifloxacin against both fluoroquinolone-resistant and -susceptible M. tuberculosis strains in mice

Genetic variability of grapevine vegetative development parameters as described with LiDAR data and associated quantitative trait loci

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