634 research outputs found

    ASPECTS REGARDING THE APPEARANCE AND THE EVOLUTION OF KEYNESIAN DOCTRINE

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    This present paper is based on the importance of the keynesian doctrine in time and tries to make a brief foray into the life and work of John Maynard Keynes, revealing important aspects related to the new concepts this doctrine brought in the history of economic thought, looking at the same time to the criticism addressed to the keynesism and studying the effects they had in the development study of economic science. The objective of this theory is “the analysis of the mechanism of the market economy in order to ensure sustainable development, reducing or eliminating the disequilibrium, when it is not verified in practice the idea of the self equilibrium through the price mechanism."Keynes wrote in an era marked by mass unemployment, by degradation and suffering at an incredible level. A reasonable person could have supported the failure of capitalism, concluding that only major institutional changes - perhaps nationalization of means of production - could restore economic health

    Design of Proportional-Resonant Control for Current Harmonic Compliance in Electric Railway Power Systems

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    This paper presents the process of designing proportional-resonant controller for a four-quadrant rectifier in electric railway traction system. In the context of ever-stricter power quality and electromagnetic compatibility standards in electric railway power systems, developers of electric locomotives need to adapt with new ways to comply. This paper develops on the process of designing a four-quadrant rectifier proportional-resonant control for mitigation of low frequency current harmonic distortion, a novel method in the field of railway EMC. The control parameters are determined through analytical modeling of the rectifier through transfer functions. For the purpose of studying the harmonic distortion mitigation effects, only the current control loop was modeled and designed. The modeling starts with simplification of the model via large-signal modeling of the power converter. The parameters of the circuit then were used to develop the transfer functions, and select the appropriate parameter values of the current loop plant. The control loop and parameters were evaluated on test locomotive to validate the control, with results confirming the improved impact on the electromagnetic compatibility and conformity to regulation

    Lower Spectral Branches of a Particle Coupled to a Bose Field

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    The structure of the lower part (i.e. ϵ\epsilon -away below the two-boson threshold) spectrum of Fr\"ohlich's polaron Hamiltonian in the weak coupling regime is obtained in spatial dimension d3d\geq 3. It contains a single polaron branch defined for total momentum pG(0)p\in G^{(0)} , where G(0)RdG^{(0)}\subset {\mathbb R}^d is a bounded domain, and, for any pRdp\in {\mathbb R}^d, a manifold of polaron + one-boson states with boson momentum qq in a bounded domain depending on pp. The polaron becomes unstable and dissolves into the one boson manifold at the boundary of G(0)G^{(0)}. The dispersion laws and generalized eigenfunctions are calculated

    GREEN ENERGY - THE FUTURE ENERGY WITHIN BIOTERRA UNIVERSITY CAMPUS

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    Green energies are widely implemented worldwide and also in our country. Our paper provides its applicability in  terms of  facilities within Bioterra University central campus in Bucharest and also in our Tourist and Students Practice Units located in Predeal – "TreiBrazi", Buşteni –" Zamora" , Danube Delta –"Baltenii de Sus" and at the Seaside - EforieSud and Comorova Forest, Neptun resort (all being owned by Bioterra University of Bucharest).At the United Nations Conference in Paris (held on 12 December 2015) regarding the  Climate change,  the partners   reached a New Global Climate change Agreement: limiting global warming, well below 2 Celsius degrees, underlining the importance of using of the non-polluting renewable energies. Beyond this limit, the scientists fear of the next irreversible effects:- repeated extreme events - cyclones, droughts, etc.;- decline of agricultural yields;- extinction of some species. Rising with +2 Celsius degrees, the sea level will increase with 40 cm till 2100 year; rising with + 4-5 Celsius degrees, the sea level will increasewith 80 cm and it will continue to ascend

    Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx

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    Gene expression and its regulation can vary substantially across tissue types. In order to generate knowledge about gene expression in human tissues, the Genotype-Tissue Expression (GTEx) program has collected transcriptome data in a wide variety of tissue types from post-mortem donors. However, many tissue types are difficult to access and are not collected in every GTEx individual. Furthermore, in non-GTEx studies, the accessibility of certain tissue types greatly limits the feasibility and scale of studies of multi-tissue expression. In this work, we developed multi-tissue imputation methods to impute gene expression in uncollected or inaccessible tissues. Via simulation studies, we showed that the proposed methods outperform existing imputation methods in multi-tissue expression imputation and that incorporating imputed expression data can improve power to detect phenotype-expression correlations. By analyzing data from nine selected tissue types in the GTEx pilot project, we demonstrated that harnessing expression quantitative trait loci (eQTLs) and tissue-tissue expression-level correlations can aid imputation of transcriptome data from uncollected GTEx tissues. More importantly, we showed that by using GTEx data as a reference, one can impute expression levels in inaccessible tissues in non-GTEx expression studies

    HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

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    The resolution of genome-wide association studies (GWAS) is limited by the linkage disequilibrium (LD) structure of the population being studied. Selecting the most likely causal variants within an LD block is relatively straightforward within coding sequence, but is more difficult when all variants are intergenic. Predicting functional non-coding sequence has been recently facilitated by the availability of conservation and epigenomic information. We present HaploReg, a tool for exploring annotations of the non-coding genome among the results of published GWAS or novel sets of variants. Using LD information from the 1000 Genomes Project, linked SNPs and small indels can be visualized along with their predicted chromatin state in nine cell types, conservation across mammals and their effect on regulatory motifs. Sets of SNPs, such as those resulting from GWAS, are analyzed for an enrichment of cell type-specific enhancers. HaploReg will be useful to researchers developing mechanistic hypotheses of the impact of non-coding variants on clinical phenotypes and normal variation. The HaploReg database is available at http://compbio.mit.edu/HaploReg.National Institutes of Health (U.S.) (R01-HG004037)National Institutes of Health (U.S.) (RC1-HG005334)National Science Foundation (U.S.) (HG005334

    Assessment of the total precipitable water from a sun photometer, microwave radiometer and radiosondes at a continental site in southeastern Europe

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    In this study, we discuss the differences in the total precipitable water (TPW), retrieved from a Cimel sun photometer operating at a continental site in southeast Europe, between version 3 (V3) and version 2 (V2) of the AErosol RObotic NETwork (AERONET) algorithms. In addition, we evaluate the performance of the two algorithms comparing their product with the TPW obtained from a collocated microwave radiometer and nearby radiosondes during the period 2007–2017. The TPW from all three instruments was highly correlated, showing the same annual cycle, with lower values during winter and higher values during summer. The sun photometer and the microwave radiometer depict the same daily cycle, with some discrepancies during early morning and late afternoon due to the effect of solar zenith angle on the measurements of the photometer. The TPW from V3 of the AERONET algorithm has small differences compared with V2, mostly related to the use of the new laboratory-based temperature coefficients used in V3. The microwave radiometer measurements are in good agreement with those obtained by the radiosonde, especially during night-time when the differences between the two instruments are almost negligible. The comparison of the sun photometer data with high-quality independent measurements from radiosondes and the radiometer shows that the absolute differences between V3 and the other two datasets are slightly higher compared with V2. However, V3 has a lower dependence from the TPW and the internal sensor temperature, indicating a better performance of the retrieving algorithm. The calculated one-sigma uncertainty for V3 as estimated, from the comparison with the radiosondes, is about 10&thinsp;%, which is in accordance with previous studies for the estimation of uncertainty for V2. This uncertainty is further reduced to about 6&thinsp;% when AERONET V3 is compared with the collocated microwave radiometer. To our knowledge, this is the first in-depth analysis of the V3 TPW, and although the findings presented here are for a specific site, we believe that they are representative of other mid-latitude continental stations.</p
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