6,300 research outputs found
Projection transparencies from printed material
Method for preparing project transparencies, or view graphs, permits the use of almost any expendable printed material, pictures, charts, or text, in unlimited color or black and white. The method can be accomplished by either of two techniques, with a slight difference in materials
Optimal monopoly investment and capacity utilization under random demand
Unique value-maximizing programs of irreversible capacity investment and capacity utilization are described and shown to exist under general conditions for monopolist exhibiting capital adjustment costs and serving random consumer demand for a nondurable good over an infinite horizon. Stationary properties of these programs are then fully characterized under the assumption of serially independent demand disturbances. Optimal monopoly behavior in this case includes acquisition of a constant and positive level of capacity, the maintenance of a positive expected value of excess capacity in each period, and an asymmetrical response of price to unanticipated fluctuations in consumer demand. Under a general form of Markovian demand, the effect of uncertainty on irreversible capacity investment is also described in terms of the discounted flow of expected revenue accruing to the marginal unit of existing capacity and the option value of deferring the acquisition of additional capital. The option value of deferring such acquisition, created by the irreversibility of capacity investment, is characterized directly in terms of the value function of the firm, and is then shown to be zero in a stationary equilibrium with serially independent demand disturbances. The response of investment to increase demand uncertainty depends, as a result, directly on the properties of the marginal revenue product of capital. A non-negative response of optimal capacity to increased uncertainty in market demand is demonstrated for a general class of aggregate consumer preferences.Industrial capacity
Managing Stored Data For Mobile Apps: Survey Of Apps And Case Study
Stored data is a critical component of any application. The stored data component of mobile applications (apps) presents special considerations. This paper examines the management of stored data for mobile apps. It identifies three types of mobile apps and describes the stored data characteristics of each type. It presents decision factors for selecting a data storage approach for a mobile app and the impact of the factors on the usability of the app. The paper surveys over 70 apps in a specific domain (that of walking the Camino de Santiago in Spain) to examine their data storage characteristics. Finally the paper presents a case study of the development of one app in this domain (eCamino). The paper concludes that in the domain examined the data storage approach selected for a mobile app depends on the characteristics of the situation in which the app will be used
Correspondence from E.B. Lovejoy, August 11, 1862
Correspondence from E.B. Lovejoy regarding absent soldiers from Androscoggin Countyhttps://digitalmaine.com/absent_soldiers/1008/thumbnail.jp
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A model for the determination of optimum setting dimensions for tractor yard/swing operations
A problem of interest to forest managers is the optimum arrangement of truck roads and landings for economical logging operations.
This problem becomes more complex if,a combined yarding and swinging
operation is considered. I,t is possible to formulate a mathematical
model to express the cost per unit volume for a particular configuration
of truck roads, landings, and swing roads arranged to accommodate
this type of harvest operation. Then, any of several
numerical methods may be employed to assess the sought-for optimum
configuration. The parameters of interest are the truck road spacing,
landing spacing, and swing road length that produce the smallest
logging cost. This paper critically examines several assumptions
made in formulation of the problem, including yarding cost computation,
tractor movement patterns, and average yarding distance.
This paper uses a numerical method not frequently employed with
constrained objective functions: Newton Multivariate Gradient
Iteration. A computer program was developed to implement the
iteration procedure, using a Hewlett-Packard 9830A Desktop Computer.
The solution procedure reduced iterations required for convergence
from several thousand experienced with exhaustive enumeration techniques
to less than thirteen. The use of this gradient method,
observations on its behavior, and insights into the analytical
approach to a complex problem are the subjects of this paper
The association between long-term conditions and uptake of population-based screening for colorectal cancer: results from two English cohort studies
Introduction: Uptake of screening for colorectal cancer (CRC) can reduce mortality, and population-based screening is offered in England. To date, there is little evidence on the association between having a long-term condition (LTC) and CRC screening uptake. The objective of this study was to examine the association between having an LTC and uptake of CRC screening in England with the guaiac fecal occult blood test, with a particular focus on common mental disorders. Methods: The study was a preregistered secondary analysis of two cohorts: first, a linked data set between the regional Yorkshire Health Study (YHS) and the National Health Service National Bowel Cancer Screening Program (BCSP, years 2006–2014); second, the national English Longitudinal Study of Ageing (ELSA, years 2014–2015). Individuals eligible for BCSP screening who participated in either the YHS (7,142) or ELSA Wave 7 (4,099) were included. Study registration: ClinicalTrials.gov, number NCT02503969. Results: In both the cohorts, diabetes was associated with lower uptake (YHS odds ratio [OR] for non-uptake 1.35, 95% CI 1.03–1.78; ELSA 1.33, 1.03–1.72) and osteoarthritis was associated with increased uptake (YHS 0.75, 0.57–0.99; ELSA 0.76, 0.62–0.93). After controlling for broader determinants of health, there was no evidence of significantly different uptake for individuals with common mental disorders. Conclusion: Two large independent cohorts provided evidence that uptake of CRC screening is lower among individuals with diabetes and higher among individuals with osteoarthritis. Further work should compare barriers and facilitators to screening among individuals with either of these conditions. This study also demonstrates the benefits of data linkage for improving clinical decision-making
The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein.
Atherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality
AbstractOBJECTIVESThis study was undertaken to determine whether atherosclerosis of the ascending aorta is a predictor of long-term neurologic events and mortality.BACKGROUNDAtherosclerosis of the thoracic aorta has been recently considered a significant predictor of neurologic events and peripheral embolism, but not of long-term mortality.METHODSLong-term follow-up (a total of 5,859 person-years) was conducted of 1,957 consecutive patients ≥50 years old who underwent cardiac surgery. Atherosclerosis of the ascending aorta was assessed intraoperatively (epiaortic ultrasound) and patients were divided into four groups according to severity (normal, mild, moderate or severe). Carotid artery disease was evaluated (carotid ultrasound) in 1,467 (75%) patients. Cox proportional-hazards regression analysis was performed to assess the independent effect of predictors on neurologic events and mortality.RESULTSA total of 491 events occurred in 472 patients (neurologic events 92, all-cause mortality 399). Independent predictors of long-term neurologic events were: hypertension (p = 0.009), ascending aorta atherosclerosis (p = 0.011) and diabetes mellitus (p = 0.015). The independent predictors of mortality were advanced age (p < 0.0001), left ventricular dysfunction (p < 0.0001), ascending aorta atherosclerosis (p < 0.0001), hypertension (p = 0.0001) and diabetes mellitus (p = 0.0002). There was >1.5-fold increase in the incidence of both neurologic events and mortality as the severity of atherosclerosis increased from normal-mild to moderate, and a greater than threefold increase in the incidence of both as the severity of atherosclerosis increased from normal-mild to severe.CONCLUSIONSAtherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality. These results provide additional evidence that in addition to being a direct cause of cerebral atheroembolism, an atherosclerotic ascending aorta may be a marker of generalized atherosclerosis and thus of increased morbidity and mortality
A systematic review of naturalistic interventions in refugee populations
Naturalistic interventions with refugee populations examine outcomes following mental health interventions in existing refugee service organisations. The current review aimed to examine outcomes of naturalistic interventions and quality of the naturalistic intervention literature in refugee populations with the view to highlight the strengths and limitations of naturalistic intervention studies. Database search was conducted using the search terms ‘refugee’, ‘asylum seeker’, ‘treatment’, ‘therapy’ and ‘intervention. No date limitations were applied, but searches were limited to articles written in English. Seven studies were identified that assessed the outcome of naturalistic interventions on adult refugees or asylum seekers in a country of resettlement using quantitative outcome measures. Results showed significant variation in the outcomes of naturalistic intervention studies, with a trend towards showing decreased symptomatology at post-intervention. However, conclusions are limited by methodological problems of the studies reviewed, particularly poor documentation of intervention methods and lack of control in the design of naturalistic intervention studies. Further examination of outcomes following naturalistic interventions is needed with studies which focus on increasing the rigour of the outcome assessment process
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