Maternal Factors Related to Parenting Young Children with Congenital Heart Disease

The purpose of this study was to compare the early child-rearing practices between mothers of young children with congenital heart disease (CHD) and mothers of healthy children. In addition, maternal stress, parental developmental expectations, and the early behavioral and emotional development of their children were explored. Maccoby’s (1992) socialization theory emphasizing the reciprocal nature of mother-child interactions provided the framework for this study. Findings from quantitative self-report measures and videotaped parent-child interactions showed a remarkable similarity between mothers of children with CHD and mothers of healthy children. In contrast, qualitative data revealed important differences with mothers of CHD children reporting high levels of vigilance with their children. The important role of promoting the principle of normalization among mothers of children with CHD and ensuring a sufficient support system is discussed

Challenging Behaviors in Young Children: The Father\u27s Role

In this study, the authors examined the parenting practices, developmental expectations, and stress levels of 136 fathers and the challenging and prosocial behaviors of their 1- to 5-year-old children. In addition, the authors systematically addressed fathers\u27 qualitative concerns about their parenting. The authors divided the participants into 4 groups and controlled for family socioeconomic status (SES) and the focus child\u27s gender. Results showed a significantly higher use of corporal and verbal punishment and parenting stress among lower income fathers. Secondary analyses demonstrated a significant effect of paternal disciplinary practices that emphasized the frequent use of corporal and verbal punishment on child behavior problems, regardless of SES level. On a positive note, fathers from both lower and higher SES groups had reasonable developmental expectations for their boys and girls, and they reported similar frequencies of their children\u27s prosocial behavior. The authors discuss the need for early parent education programs that include fathers and that teach specific strategies to address child behavior problems

Parenting Among Hispanic and Anglo-American Mothers With Young Children

The authors examined parenting practices and developmental expectations among 38 Hispanic and 38 Anglo-American mothers living in the United States. Mothers of children 3 to 5 years of age completed the Parent Behavior Checklist (R. A. Fox, 1994), a 100-item measure of parents\u27 developmental expectations, discipline, and nurturing practices. In addition, the authors appraised the Hispanic mothers\u27 acculturation and selected them for participation if their scores on an acculturation scale indicated (a) that their lifestyle was predominantly Hispanic and (b) that they had not been assimilated into the dominant culture. The 2 ethnic groups were also divided by socioeconomic status (SES). There were significant main effects for ethnicity and SES on the discipline and nurturing scores but not on the expectations scores. The Hispanic and higher SES mothers reported higher discipline and lower nurturing scores than did the Anglo-American and lower SES mothers. An unexpected finding was the tendency for higher SES Hispanic mothers to report more frequent use of discipline than the other 3 groups

Parenting Young Children: Comparison of a Psychoeducational Program in Mexico and the United States

The purpose of this study was to compare the cross-cultural effectiveness of a psychoeducational program with 82 Mexican and 63 American mothers with very young children. The 10-hour program was presented by trained facilitators in Mexico and the United States to small groups of mothers. Results showed that the both groups of mothers significantly increased their expectations and use of nurturing strategies and reduced their use of verbal and corporal punishment with their young children following the program. In addition, the reported frequency of child behavior problems decreased significantly at post-test. The similar results obtained across cultures were explained based on research finding similar parenting practices with young children between Mexican and American parents

Geomorphological significance of Ontario Lacus on Titan: Integrated interpretation of Cassini VIMS, ISS and RADAR data and comparison with the Etosha Pan (Namibia)

International audienceOntario Lacus is the largest lake of the whole southern hemisphere of Titan, Saturn's major moon. It has been imaged twice by each of the Cassini imaging systems (Imaging Science Subsystem (ISS) in 2004 and 2005, Visual and Infrared Mapping Spectrometer (VIMS) in 2007 and 2009 and Radar in 2009 and 2010). In this study, we take advantage of each imaging dataset to establish a global survey of Ontario Lacus' environment from 2005 to 2010. We perform a geomorphological mapping and interpretation of Ontario Lacus, mainly based on a joint analysis of VIMS and Radar SAR datasets, along with the T49 altimetric profile acquired in December 2008. The morphologies observed on Ontario Lacus are compared to landforms of a semi-arid terrestrial analog, which closely resembles Titan's lakes: the pans of the Etosha Basin, located in Namibia. From this comparison, we infer that Ontario Lacus is an extremely flat depression where liquids, only located in the darkest areas in the Radar data, cover topographic lows where the "alkanofer" would raise above the depression floor. The rest of the depression appears rather as a muddy flat surface likely composed of a thick coating of photon-absorbing materials, explaining its still rather dark appearance in the infrared and radar data. We also determined whether surface changes occurred during the 5 years time interval between 2005 and 2010. We found that the depression contour is constant at the resolution of ISS and VIMS data, both being consistent with the depression contour derived from the Radar data. Our interpretation, in which the liquids are located only in some parts of Ontario Lacus, agrees with the lack of significant change of the depression contour between 2007 (and 2005 with more uncertainties) and 2010

A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

BACKGROUND: Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease might lead to interventions that combat the tuberculosis epidemic. We aimed to assess whether global gene expression measured in whole blood of healthy people allowed identification of prospective signatures of risk of active tuberculosis disease. METHODS: In this prospective cohort study, we followed up healthy, South African adolescents aged 12-18 years from the adolescent cohort study (ACS) who were infected with M tuberculosis for 2 years. We collected blood samples from study participants every 6 months and monitored the adolescents for progression to tuberculosis disease. A prospective signature of risk was derived from whole blood RNA sequencing data by comparing participants who developed active tuberculosis disease (progressors) with those who remained healthy (matched controls). After adaptation to multiplex quantitative real-time PCR (qRT-PCR), the signature was used to predict tuberculosis disease in untouched adolescent samples and in samples from independent cohorts of South African and Gambian adult progressors and controls. Participants of the independent cohorts were household contacts of adults with active pulmonary tuberculosis disease. FINDINGS: Between July 6, 2005, and April 23, 2007, we enrolled 6363 participants from the ACS study and 4466 from independent South African and Gambian cohorts. 46 progressors and 107 matched controls were identified in the ACS cohort. A 16 gene signature of risk was identified. The signature predicted tuberculosis progression with a sensitivity of 66·1% (95% CI 63·2-68·9) and a specificity of 80·6% (79·2-82·0) in the 12 months preceding tuberculosis diagnosis. The risk signature was validated in an untouched group of adolescents (p=0·018 for RNA sequencing and p=0·0095 for qRT-PCR) and in the independent South African and Gambian cohorts (p values <0·0001 by qRT-PCR) with a sensitivity of 53·7% (42·6-64·3) and a specificity of 82·8% (76·7-86) in the 12 months preceding tuberculosis. INTERPRETATION: The whole blood tuberculosis risk signature prospectively identified people at risk of developing active tuberculosis, opening the possibility for targeted intervention to prevent the disease. FUNDING: Bill & Melinda Gates Foundation, the National Institutes of Health, Aeras, the European Union, and the South African Medical Research Council

Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.

Rationale: Contacts of patients with tuberculosis (TB) constitute an important target population for preventive measures because they are at high risk of infection with Mycobacterium tuberculosis and progression to disease.Objectives: We investigated biosignatures with predictive ability for incident TB.Methods: In a case-control study nested within the Grand Challenges 6-74 longitudinal HIV-negative African cohort of exposed household contacts, we employed RNA sequencing, PCR, and the pair ratio algorithm in a training/test set approach. Overall, 79 progressors who developed TB between 3 and 24 months after diagnosis of index case and 328 matched nonprogressors who remained healthy during 24 months of follow-up were investigated.Measurements and Main Results: A four-transcript signature derived from samples in a South African and Gambian training set predicted progression up to two years before onset of disease in blinded test set samples from South Africa, the Gambia, and Ethiopia with little population-associated variability, and it was also validated in an external cohort of South African adolescents with latent M. tuberculosis infection. By contrast, published diagnostic or prognostic TB signatures were predicted in samples from some but not all three countries, indicating site-specific variability. Post hoc meta-analysis identified a single gene pair, C1QC/TRAV27 (complement C1q C-chain / T-cell receptor-α variable gene 27) that would consistently predict TB progression in household contacts from multiple African sites but not in infected adolescents without known recent exposure events.Conclusions: Collectively, we developed a simple whole blood-based PCR test to predict TB in recently exposed household contacts from diverse African populations. This test has potential for implementation in national TB contact investigation programs

Overparenting and Narcissism in Young Adults: The Mediating Role of Psychological Control

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Overparenting, or “helicopter parenting,” can be generally characterized as parenting that is well-intentioned, but over-involved and intrusive. This style of parenting has been especially highlighted in the lives of young adults, who may be inhibited by this form of parenting in the appropriate development of autonomy and independence. Overparenting shares conceptual similarities with parents’ psychological control practices, which involve emotional and psychological manipulation of children (e.g., inducing guilt, withholding love as a form of control). Although these constructs contain key differences, both have been linked to narcissism in young adults, by way of parental over-involvement in children’s lives. Thus, we sought to explore parental psychological control as a mediator between overparenting and narcissism, including in regard to both grandiose and vulnerable narcissistic phenotypes. Participants included 380 young adult college students (age range: 18–26 years) who completed the Pathological Narcissism Inventory, as well as reports of their parents’ behaviors related to overparenting and psychological control. Mediation analyses through Process in SPSS supported the hypothesized role of parental psychological control as a mediator between overparenting and narcissistic traits, including traits related to both grandiose and vulnerable narcissism. Effect sizes for each analysis were modest. This study further clarifies the nature of overparenting, and speaks to the need for further research in establishing the mechanisms by which overparenting may lead to narcissistic traits among young adults