Impacts of Water and Sanitation Activities on the Environment in the Upper Mara Basin

The provision of reliable and safe water supplies is an essential element in improving the quality of life for mankind. However, over time the natural resource base has become severely stressed due to unsustainable use of the resources. This study was undertaken to evaluate the impacts of water, sanitation and hygiene (WASH) activities on the environment in the upper Mara River basin. Sampled water and sanitation projects were identified by observation and Geographic Information System (GIS) was used to map and report on these projects. Impacts of the projects on land and environmental quality were assessed using Land Quality Indicators (LQI); fresh water quality, solid and liquid waste generation and management and soil erosion. Water samples were analyzed for physical, chemical and bacteriological parameters and only 23.4% of sampled water sources were found suitable as domestic water sources. Most open water sources were contaminated with E. Coli caused by open defecation in the basin which on average was 38%. The study showed that, 21.3% of the sampled water supply projects had evidence of soil erosion around them which was mainly caused by livestock overcrowding at water points. Among the wastewater generating and management activities in upper Mara basin, Bomet municipal stabilization pond posed the greatest pollution threat to the environment since it lacked capacity to treat waste water to standards before it overflowed into the environment. This study recommended that WASH project implementers, users and managers should plan for and implement environmentally sustainable projects. In addition, WASH stakeholders in the basin should make comprehensive efforts to provide improved water sources and sanitation to all the residents. Keywords: Water, Sanitation, Environment, Impact

Agroforestry study visit to Malawi and Zambia

The study visit to agroforestry projects in Malawi and Zambia gave participants an opportunity to see the latest advances in agroforestry development in the two countries, achieved through collaboration among regional research and development agenciesA CTA study visit to agroforestry projects in Malawi and Zambia..

Transitional Enrolment Trends within the Different Educational Levels in Kenya: An Analysis of Promoting Facets

Countries in Sub-Saharan Africa have for decades grappled with bridging the gap in enrolment numbers between male and female students. Education for All (EFA) goals have provided guidance to these countries on attainment of gender equality in education. EFA goal number 5 articulates the international commitments aimed at achieving global gender equality in education by 2015. This is to be arrived at by increasing the enrolment of female learners at different levels of education. The Ministry of Education in Kenya developed policies and strategies to enable an increase in female students enrolling in school. With these policies and strategies, Kenya has realised tremendous successes in terms of enrolment numbers. However the country still faces challenges in some geographic areas. In as much as there is an increase in the number of girls participating in primary and secondary school levels, Kenya is yet to attain gender equality in education. The number of boys in these levels of education still surpass that of girls by a concerning proportion. Interestingly these trends change in post secondary education levels. Universities have recorded an amplified enrolment of female. This paper documents trends in enrolment numbers by gender in primary, secondary and post-secondary levels of education in Kenya. Further, the paper interrogates the facets that promote the shifts in the enrolment trends. Keywords: Enrolment trends; Gender inequality in education; Education in Kenya; Gender and Education; Gender differences in Education

Anti-inflammatory activities of dichloromethane-methanolic leaf and stem bark extracts of Ximenia americana in mice models

Introduction: Ximenia americana is a highly branched shrub mainly found in tropics of Asia, Africa, New Zealand, Central and South America among others. In most parts of Africa, X. americana is used in folklore to treat various disorders such as oedema, pain, fever, helminthiasis, diarrhea and burns among others. There is no published data on anti-inflammatory activities of organic extracts of X. americana. It is against this background that this research was carried out. The study tested for the anti-inflammatory activities of dichloromethane-methanolic (DCM-MeOH) leaf and stem bark extracts of X. americana in rats.Methods: The plant materials were collected from Mbeere North sub-county, Embu county, Kenya. Methanol and dichloromethane in the ratio of 1:1 was used to extract the active compounds. Five to 6 weeks old Swiss Albino mice were employed for the anti-inflammatory studies. Animals were divided into 6 groups of 5 rats each: normal, negative, reference and three experimental groups (50, 100 and 150 mg/kg body weight). Inflammation was induced experimentally using carrageenan. The experimental groups were treated with predetermined dose quantities of prepared extracts. Diclofenac was used as the reference drug. Data was analyzed using one-way analysis of variance (ANOVA).Results: The extracts from the leaves reduced hind paw circumference by between 0.91 and 16.90 while the stem bark extracts reduced hind paw circumference by between 5.84 and 29.00. Diclofenac reduced right hind paw circumference by 1.32-29.60. Qualitative phytochemical screening showed presence of alkaloids, flavonoids, steroids, saponins, cardiac glycosides, phenolics and terpenoids in the extract.Conclusion: The study established that the DCM-MeOH leaf and stem bark extracts of X. americana is effective in management of inflammation and therefore it can be explored as a possible bio-resource in the development of herbal medicines

Phytochemical screening and antipyretic activities of dichloromethane-methanolic leaf and stem bark extracts of Ximenia americana in rat models

Introduction: In most parts of Africa, Ximenia americana is used in folklore to treat various disorders such as oedema, pain, fever, helminthiasis, diarrhoea, burns among other diseases. This study tested the antipyretic activities of dichloromethane-methanolic (DCM-MeOH) stem bark and leaf extracts of X. americana in rats. Qualitative phytochemical screening was also done to evaluate the presence of alkaloids, flavonoids, steroids, saponins, cardiac glycosides, phenolics and terpenoids in the extract.Methods: The plant materials were collected from Mbeere North sub-county, Embu county, Kenya. Methanol and dichloromethane in the ratio of 1:1 was used to extract the active compounds. Two to three months old male Wister rats were employed for the antipyretic studies. Animals were divided into six groups of five rats each: normal, negative, reference and three experimental groups (50, 100 and 150 mg/kg body weight). Pyrexia was induced experimentally using turpentine. The experimental groups were treated with predetermined dose quantities of prepared extracts. Aspirin was used as the reference drug. Data were analyzed using one-way analysis of variance (ANOVA).Results: The extracts from the leaves lowered rectal temperature by 0.45 to 2.11 while the stem bark extracts lowered rectal temperature in the range of 0.71 to 2.13. Aspirin lowered the rectal temperature in the range of 0.74 and 1.67. Qualitative phytochemical screening showed presence of alkaloids, flavonoids, steroids, saponins, cardiac glycosides, phenolics and terpenoids in the extract.Conclusion: DCM-MeOH leaf and stem bark extracts of X. americana is effective in management of fever and therefore it can be explored as a possible bio-resource in the development of herbal antipyretic medicines

Innovations in Climate Risk Management: Protecting and Building Rural Livelihoods in a Variable and Changing Climate

We argue that more effective management of climate risk must be part of the response of the international agriculture community to the double crisis of persistent poverty and a changing climate. The most promising opportunities to adapt to climate change involve action on shorter time scales that also contributes to immediate development challenges. Climate risk management (CRM) combines systematic use of climate information, and technology that reduces vulnerability and policy that transfers risk. The cost of climate risk comes both through damaging extreme events and through forfeited opportunity in climatically-favorable years. Effective CRM therefore involves managing the full range of variability, balancing hazard management with efforts to capitalize on opportunity. We discuss several innovations for managing climate risk in agriculture, which have not yet been fully mainstreamed in international agricultural research-for-development. First, effective rural climate information services enable farmers to adopt technology, intensify production, and invest in more profitable livelihoods when conditions are favorable; and to protect families and farms against the long-term consequences of adverse extremes. Second, information and decision support systems synthesize historic, monitored and forecast climate information into forms that are directly relevant to institutional decisions (planning, trade, food crisis response) that impact farmer livelihoods. Third, innovations in index-based insurance and credit overcome some of the limitations of traditional insurance, and are being applied to pre-financing food crisis response, and to removing credit constraints to adopting improved technology. We present a typology of CRM interventions around the concept of dynamic poverty traps

Building capacity in implementation science research training at the University of Nairobi.

BACKGROUND: Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential for health care systems, especially in low-resource settings, to increase capacity to implement evidence-based practices, by training professionals in implementation science. With support from the Medical Education Partnership Initiative, the University of Nairobi has developed a training program to build local capacity for implementation science. METHODS: This paper describes how the University of Nairobi leveraged resources from the Medical Education Partnership to develop an institutional program that provides training and mentoring in implementation science, builds relationships between researchers and implementers, and identifies local research priorities for implementation science. RESULTS: The curriculum content includes core material in implementation science theory, methods, and experiences. The program adopts a team mentoring and supervision approach, in which fellows are matched with mentors at the University of Nairobi and partnering institutions: University of Washington, Seattle, and University of Maryland, Baltimore. A survey of program participants showed a high degree satisfaction with most aspects of the program, including the content, duration, and attachment sites. A key strength of the fellowship program is the partnership approach, which leverages innovative use of information technology to offer diverse perspectives, and a team model for mentorship and supervision. CONCLUSIONS: As health care systems and training institutions seek new approaches to increase capacity in implementation science, the University of Nairobi Implementation Science Fellowship program can be a model for health educators and administrators who wish to develop their program and curricula

ANTIINFLAMMATORY PROPERTIES OF DICHLOROMETHANE: METHANOLIC LEAF EXTRACTS OF CAESALPINIA VOLKENSII AND MAYTENUS OBSCURA IN ANIMAL MODELS

Objective: Inflammation is the reaction to injury of the living tissues. Conventional medication of inflammation is expensive and arguably associated with various severe adverse effects hence the need to develop herbal agents that are effective as alternative. Caesalpinia volkensii and Maytenus obscura are plants that grow in Mbeere County of Eastern region of Kenya. This study was designed to evaluate the anti-inflammatory activity of C. volkensii and M. obscura plants. Methods: Experimental animals were divided in to four groups; normal group, diseased negative control group, diseased reference group and diseased experimental groups. Inflammation was inducted into the mice using carrageenan. The experimental groups were treated with leaf extracts of the plants at concentration of 50 mg/kg, 100 mg/kg and 150 mg/kg. Anti-inflammatory activities in rats were compared with diclofenac (15 mg/kg) as the standard conventional drug. Results: The leaf extracts of C. volkensii reduced the paw edema by between 6.50%-13.42% while the extracts of M. obscura reduced it by between 4.94%-22.36%. Diclofenac reduced the paw edema by between 4.11%-10.47%. Conclusion: The phytochemical screening results showed that the extracts of C. volkensii had flavonoids, steroids and phenolics while the leaf extracts M. obscura had phenolics, terpenoids and saponins. Flavonoids, saponins and phenolics have been associated with anti-inflammatory activities. Therefore, the study has established that the DCM: methanolic leaf extracts of Caesalpinia volkensii and Maytenus obscura are effective in management of inflammation

Risk factors associated with the epilepsy treatment gap in Kilifi, Kenya: a cross-sectional study.

BACKGROUND: Many people with epilepsy in low-income countries do not receive appropriate biomedical treatment. This epilepsy treatment gap might be caused by patients not seeking biomedical treatment or not adhering to prescribed antiepileptic drugs (AEDs). We measured the prevalence of and investigated risk factors for the epilepsy treatment gap in rural Kenya. METHODS: All people with active convulsive epilepsy identified during a cross-sectional survey of 232,176 people in Kilifi were approached. The epilepsy treatment gap was defined as the percentage of people with active epilepsy who had not accessed biomedical services or who were not on treatment or were on inadequate treatment. Information about risk factors was obtained through a questionnaire-based interview of sociodemographic characteristics, socioeconomic status, access to health facilities, seizures, stigma, and beliefs and attitudes about epilepsy. The factors associated with people not seeking biomedical treatment and not adhering to AEDs were investigated separately, adjusted for age. FINDINGS: 673 people with epilepsy were interviewed, of whom 499 (74%) reported seeking treatment from a health facility. Blood samples were taken from 502 (75%) people, of whom 132 (26%) reported taking AEDs, but 189 (38%) had AEDs detectable in the blood. The sensitivity and specificity of self-reported adherence compared with AEDs detected in blood were 38·1% (95% CI 31·1-45·4) and 80·8% (76·0-85·0). The epilepsy treatment gap was 62·4% (58·1-66·6). In multivariable analysis, failure to seek biomedical treatment was associated with a patient holding traditional animistic religious beliefs (adjusted odds ratio 1·85, 95% CI 1·11-2·71), reporting negative attitudes about biomedical treatment (0·86, 0·78-0·95), living more than 30 km from health facilities (3·89, 1·77-8·51), paying for AEDs (2·99, 1·82-4·92), having learning difficulties (2·30, 1·29-4·11), having had epilepsy for longer than 10 years (4·60, 2·07-10·23), and having focal seizures (2·28, 1·50-3·47). Reduced adherence was associated with negative attitudes about epilepsy (1·10, 1·03-1·18) and taking of AEDs for longer than 5 years (3·78, 1·79-7·98). INTERPRETATION: The sensitivity and specificity of self-reported adherence is poor, but on the basis of AED detection in blood almost two-thirds of patients with epilepsy were not on treatment. Education about epilepsy and making AEDs freely available in health facilities near people with epilepsy should be investigated as potential ways to reduce the epilepsy treatment gap. FUNDING: Wellcome Trust