No Room to Live: Urban Overcrowding in Edwardian Britain

We study the extent of overcrowding amongst British urban working families in the early 1900s and find major regional differences. In particular, a much greater proportion of households in urban Scotland were overcrowded than in the rest of Britain and Ireland. We investigate the causes of this spatial distribution of overcrowding and find that prices, especially rents and wages are the proximate causes of the phenomenon. In large cities, ports and cities specialising in old heavy industries high rent and overcrowding are more prevalent. Within cities, but not between cities, variations in infant mortality are clearly correlated with measures of overcrowding. All the findings are consistent with a core-periphery view of urban households choosing the location and size of housing to balance the health risks of overcrowding against the risks associated with lower and less regular incomes in places where rents are lower.poverty, rent, overcrowding, Scotland, 1904, infant mortality, Bowley

Evaluating three frameworks for the value of information: adaptation to task characteristics and probabilistic structure

We identify, and provide an integration of, three frameworks for measuring the informativeness of cues in a multiple-cue judgment task. Cues can be ranked by information value according to expected information gain (Bayesian framework), cue-outcome correlation (Correlational framework), or ecological validity (Ecological framework). In three experiments, all frameworks significantly predicted information acquisition, with the Correlational (then the Bayesian) framework being most successful. Additionally, participants adapted successfully to task characteristics (cue cost, time pressure, and information limitations) – altering the gross amount of information acquired, but not responding to more subtle features of the cues’ information value that would have been beneficial. Rational analyses of our task environments indicate that participants' behavior can be considered successful from a boundedly rational standpoint

Alterations in immunoglobulin levels in uninfected children born to HIV infected women

Background Immunoglobulin levels are known to be elevated in HIV infected children. However, little is known about the effect of maternal HIV infection and the maternal altered immune system on immunoglobulin levels in uninfected children. As few data are available on immunoglobulins from young healthy children, we used data from uninfected children born to hepatitis C virus (HCV) infected women as a comparison. Methods Prospective data on immunoglobulin levels were available from birth to 5 years for children enrolled in the European Collaborative Study (ECS) of children born to HIV-1 infected women and from birth to 24 months for children enrolled in the European Paediatric HCV Network (EPHN). Children born to HIV/HCV co-infected women were excluded. Smoothers (running means) illustrated patterns of immunoglobulins over age by infection status. Associations between infant and maternal factors and child log10 total IgG, IgM and IgA levels were quantified in linear regression analyses allowing for repeated measures within child. Further analyses were performed using only data of HIV exposed uninfected children to investigate associations between child immunoglobulins and maternal immunological and virological factors and anti-retroviral therapy exposure. Results 1751 HIV uninfected, 190 HIV infected children (ECS), 173 HCV uninfected and 30 HCV infected children (EPHN) were included. HIV infected children had higher levels of all immunoglobulins compared to uninfected children over all ages. HIV uninfected children had significantly higher IgG, IgM and IgA levels than HCV uninfected children upto at least 24 months, adjusting for gender, prematurity and race. Prematurity was associated with significantly lower levels of immunoglobulins upto 24 months. Children born to African women had higher IgG and IgA levels upto 24 months than those born to white women but lower IgM in the first 6 months. Among HIV uninfected children higher IgG levels were associated with elevated maternal IgG levels, as well for measurements from 18 months to 5 years of age. No significant effect of maternal CD4 count was observed. ART exposure was associated with significantly lower IgG levels at 6-24 months. Race was not associated with immunoglobulin levels in multivariable analyses in this sub-group. Conclusions These findings indicate significant alterations in immunoglobulin levels in uninfected children born to HIV infected women. This suggests that exposure to an activated maternal immune system is associated with an altered humoral response in children without antigen stimulation, and warrants further research

An International Classification of Functioning, Disability and Health Perspective on Physical Activity Participation Among Children with Cerebral Palsy

Children with cerebral palsy do not commonly meet the minimum recommended physical activity guidelines published by the U.S. Department of Health and Human Services. Children with cerebral palsy face many functional limitations which can, in turn, affect participation and activity; therefore, this study aimed to identify the predictors of participation and activity among children with cerebral palsy. The study examined associations among poverty levels, neighborhood support, accommodating services, and familial financial burdens as factors influencing participation. Data were taken from the National Survey of Children’s Health. A chi-square test for the association was executed along with a logistic regression

A History of the Audiology Program at the University of Nebraska-Lincoln: 1920 to 2015

Programs for the hearing impaired have been in existence at the University of Nebraska for many years. However, there is no comprehensive history of these efforts. This work is an attempt to provide a complete picture of these programs and to detail the history and growth of the Audiology Program at the University of Nebraska-Lincoln. When the author came to the University in 1977 audiology was already well established at the University as well as in the State. After joining the faculty, the author served in the capacity of Coordinator of the Audiology and Hearing Science Program from 1977 until his retirement in 2011 and so, is in a unique position to compile this history. As well be seen, the audiology program at UNL has been under steady development since the very early years. In addition, its focus has grown from one of educating teachers about the causes and effects of hearing loss, to providing therapeutic programs for those who have speech and hearing disabilities and providing a four year, post-baccalaureate professional degree in the form of the Doctor of Audiology (Au.D.) Audiology as a profession and course of study is an outgrowth of the profession of “speech correction” later called Speech Pathology or Speech-Language Pathology. Many of those who early on referred to themselves as “audiologists” were in fact trained in the speech pathology realm and saw a connection between hearing impairment and distorted speech and language. Thus, it is completely appropriate to begin this historical account with those early “speech correctionists-audiologists”. It is also the case that the growth of the audiology program is closely tied to the development of the Barkley Memorial Center on East Campus. For that reason, some mention will be made of the conception and construction of the Barkley Center. As previously stated, there is no central compendium of information about the development of audiology in Nebraska. The author is grateful to the Archives of the University of Nebraska-Lincoln Libraries, people with past ties to the program and who allowed themselves to be interviewed, and professional colleagues at Nebraska and elsewhere who had memories to share. Errors of omission are solely those of the author

Simulation Model to Evaluate Performance of Operational Systems and their Impact on Repair Shop Activity at a Navy Field Site

This paper presents the background and procedures leading to development of a simulation model to analyze the impact of certain decision variables on operational system performance and workloads as the repair facility of a typical Navy field site. The research examines the impact of maintenance support concepts, as implemented by changes in the decision variables, associated with the broader application of Automatic Test Equipment. The initial effort consisted of data collection and field site surveys which culminated in defining a work flow model illustrating typical repair facility operations. The work flow model is translated into a computer simulation model. The baseline model contains all the values for failure rates, delay times, and probability decision parameters derived from the available data. The simulation model is then exercised and the output data recorded for comparison with historical data to validate the model and provide a baseline for comparison as the decision parameters are varied. Of the variables exercised, it appears that the Built-in-Test (BIT), or Self-test capability, is one of the more important design considerations in the original operating systems

SSME main combustion chamber life prediction

Typically, low cycle fatigue life is a function of the cyclic strain range, the material properties, and the operating temperature. The reusable life is normally defined by the number of strain cycles that can be accrued before severe material degradation occurs. Reusable life is normally signified by the initiation or propagation of surface cracks. Hot-fire testing of channel wall combustors has shown significant mid-channel wall thinning or deformation during accrued cyclic testing. This phenomenon is termed cyclic-creep and appears to be significantly accelerated at elevated surface temperatures. This failure mode was analytically modelled. The cyclic life of the baseline SSME-MCC based on measured calorimeter heat transfer data, and the life sensitivity of local hot spots caused by injector effects were determined. Four life enhanced designs were assessed

Modeling Endogenous Technological Change for Climate Policy Analysis

The approach used to model technological change in a climate policy model is a critical determinant of its results. We provide an overview of the different approaches used in the literature, with an emphasis on recent developments regarding endogenous technological change, research and development, and learning. Detailed examination sheds light on the salient features of each approach, including strengths, limitations, and policy implications. Key issues include proper accounting for the opportunity costs of climate-related knowledge generation, treatment of knowledge spillovers and appropriability, and the empirical basis for parameterizing technological relationships. No single approach appears to dominate on all these dimensions, and different approaches may be preferred depending on the purpose of the analysis, be it positive or normative.exogenous, technology, R&D, learning, induced

Human resources needs for universal access to antiretroviral therapy in South Africa: a time and motion study

<p>Background - Although access to life-saving treatment for patients infected with HIV in South Africa has improved substantially since 2004, treating all eligible patients (universal access) remains elusive. As the prices of antiretroviral drugs have dropped over the past years, availability of human resources may now be the most important barrier to achieving universal access to HIV treatment in Africa. We quantify the number of HIV health workers (HHWs) required to be added to the current HIV workforce to achieve universal access to HIV treatment in South Africa, under different eligibility criteria.</p> <p>Methods - We performed a time and motion study in three HIV clinics in a rural, primary care-based HIV treatment program in KwaZulu-Natal, South Africa, to estimate the average time per patient visit for doctors, nurses, and counselors. We estimated the additional number of HHWs needed to achieve universal access to HIV treatment within one year.</p> <p>Results - For universal access to HIV treatment for all patients with a CD4 cell count of ≤350 cells/μl, an additional 2,200 nurses, 3,800 counselors, and 300 doctors would be required, at additional annual salary cost of 929 million South African rand (ZAR), equivalent to US$141 million. For universal treatment (‘treatment as prevention’), an additional 6,000 nurses, 11,000 counselors, and 800 doctors would be required, at an additional annual salary cost of ZAR 2.6 billion (US$ 400 million).</p> <p>Conclusions - Universal access to HIV treatment for patients with a CD4 cell count of ≤350 cells/μl in South Africa may be affordable, but the number of HHWs available for HIV treatment will need to be substantially increased. Treatment as prevention strategies will require considerable additional financial and human resources commitments.</p&gt

Long-Term Human Video Generation of Multiple Futures Using Poses

Predicting future human behavior from an input human video is a useful task for applications such as autonomous driving and robotics. While most previous works predict a single future, multiple futures with different behavior can potentially occur. Moreover, if the predicted future is too short (e.g., less than one second), it may not be fully usable by a human or other systems. In this paper, we propose a novel method for future human pose prediction capable of predicting multiple long-term futures. This makes the predictions more suitable for real applications. Also, from the input video and the predicted human behavior, we generate future videos. First, from an input human video, we generate sequences of future human poses (i.e., the image coordinates of their body-joints) via adversarial learning. Adversarial learning suffers from mode collapse, which makes it difficult to generate a variety of multiple poses. We solve this problem by utilizing two additional inputs to the generator to make the outputs diverse, namely, a latent code (to reflect various behaviors) and an attraction point (to reflect various trajectories). In addition, we generate long-term future human poses using a novel approach based on unidimensional convolutional neural networks. Last, we generate an output video based on the generated poses for visualization. We evaluate the generated future poses and videos using three criteria (i.e., realism, diversity and accuracy), and show that our proposed method outperforms other state-of-the-art works