Transmissão de energia sem contacto com aplicação em veículos eléctricos

Dissertação para obtenção do Grau de Mestre em Engenharia Electrotécnica e de ComputadoresCom o preço dos combustíveis fósseis em ascensão tornou-se imperativo procurar por novas soluções, tendo em conta que praticamente toda a indústria e meios de transporte dependem de derivados do crude. Os motores eléctricos voltaram à luz da ribalta após a sua queda nos anos 30. Mais importante é que a tecnologia, que entretanto evoluiu, permite agora pensar nos motores eléctricos como sérios concorrentes dos motores de combustão interna para utilização em veículos automóveis. O trabalho apresentado sugere a utilização de um conversor de ressonância capaz de transferir energia sem contacto para um veículo eléctrico. Foi feito um estudo a um veículo existente para se perceber as suas exigências a nível energético e estabelecer as especificações iniciais. Foram abordadas as melhores topologias conhecidas de conversores de ressonância aplicadas à entrega de potência sem fios. A geometria do transformador é essencial quando este tem os enrolamentos primário e secundário separados por vários centímetros, pelo que várias soluções foram consideradas e avaliadas. O controlo dos processos de ressonância não é fácil, motivo que justifica os recentes desenvolvimentos de mecanismos de controlo capazes de tornar o funcionamento do conversor de ressonância mais eficiente e mais suave. Esta dissertação contribui ela própria com ensaios que comprovam as hipóteses levantadas para uma forma melhorada de regulação instantânea. O método baseia-se no cálculo, em cada meio período, da quantidade de energia que é transferida da malha de ressonância para a carga. Foi ainda desenvolvido em software um meio de obter o consumo energético dum veículo eléctrico autónomo que permite análises estatísticas e permitirá num futuro próximo a criação dum sistema de gestão de baterias melhorado

Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen

The ability of the thymus to generate a population of T cells that is, for the most part, self-restricted and self-tolerant depends to a great extent on the Ags encountered during differentiation. We recently showed that mycobacteria disseminate to the thymus, which raised the questions of how mycobacteria within the thymus influence T cell differentiation and whether such an effect impacts host-pathogen interactions. Athymic nude mice were reconstituted with thymic grafts from Mycobacterium avium-infected or control noninfected donors. T cells generated from thymi of infected donors seemed generally normal, because they retained the ability to reconstitute the periphery and to respond to unspecific stimuli in vitro as well as to antigenic stimulation with third-party Ags, such as OVA, upon in vivo immunization. However, these cells were unable to mount a protective immune response against a challenge with M. avium. The observation that thymic infection interferes with T cell differentiation, generating T cells that are tolerant to pathogen-specific Ags, is of relevance to understand the immune response during chronic persistent infections. In addition, it has potential implications for the repertoire of T cells generated in patients with a mycobacterial infection recovering from severe lymphopenia, such as patients coinfected with HIV and receiving antiretroviral therapy.Fundação para a Ciência e Tecnologia and Fundo Europeu de Desenvolvimento Regional (PIC/IC/83313/2007; PTDC/SAU-MII/101663/2008) and the American-Portuguese Biomedical Research Fund. C.N., S.R., and C.N.-A. are recipients of PhD fellowships from Fundação para a Ciência e Tecnologi

Analyzing Pilot Projects of Creative Tourism in an Ultra-Peripheral Region : Which guidelines can be extracted for sustainable regional development?

Several authors have shown that some tourism typologies - i.e., rural tourism, nature-based tourism, or creative tourism - have a more predominant role in attaining regional sustainability. In this regard, this paper explores the impacts of five pilot projects of creative tourism on the sustainable development of the insular Autonomous Region of the Azores. Through direct exploratory tools, such as interviews and site analyses, the present study enabled us to provide greater insight into creative tourism projects and their relevance to the development of an ultra-peripheral island region. As part of the CREATOUR AZORES Project, this study is based on five creative tourism pilot projects operating in the Azores, Portugal. As such, it is recommended that the regional government, local authorities, and other relevant actors and players in this region actively support and create strategies to strengthen these projects (and similar initiatives) once they not only contribute to regional development and destination promotion but also promote much-desired sustainable development - once these kinds of tourism, in theory, and practice, counteract the dire effects of mass tourism.This paper is financed by Portuguese national funds through FCT–Fundação para a Ciência e a Tecnologia, I.P., project number UIDB/00685/2020 and also by the project CREATOUR Azores—Turning the Azores into a Creative Tourism Destination (ACORES-01-0145-FEDER-000127). CREATOUR Azores is coordinated by the Azores Sustainable Tourism Observatory and developed in partnership with the University of the Azores/Gaspar Frutuoso Foundation, being financed by the FEDER, through the Azores Operational Program 2020 and by regional funds, through the Regional Directorate for Science. and Technology. Also, by the project UID/SOC/04647/2013, with the financial support of FCT/MEC through national funds and, when applicable, co-financed by FEDER under the PT2020 Partnership.info:eu-repo/semantics/publishedVersio

Diet of mid-Atlantic Sowerby’s beaked whales Mesoplodon bidens

Copyright © 2011 Elsevier Ltd. All rights reserved.The first mid-Atlantic diet of Mesoplodon beaked whales is presented, from ten Sowerby's Mesoplodon bidens stranded in the Azores region between 2002 and 2009. This doubles the worldwide number of stomachs sampled, and reveals new feeding habits for this species. The mean number of prey items per stomach was 85±89 (range: 12–238), with fish accounting for 99.3% and cephalopods contributing less than 1% of total prey. Fish otoliths from 15 families and cephalopod lower mandibles from three families were identified, representing 22 taxa. The diet consisted mainly of small mid-water fish, the most numerous being Diaphus sp., Lampanyctus sp. and Melamphaidae species. Myctophids were present in all stranded individuals, followed by Diretmidae, Melamphaidae and Opisthoproctus soleatus, while the remaining fish species were scarce or single occurrences. Consistency of diet in four different years reveals a divergence from all previous records in continental areas, where mainly neritic and shelf-break benthopelagic fish species have been reported. Mid-Atlantic Sowerby's beaked whales' showed dietary plasticity, feeding on the most abundant mid-water groups occurring between 0 and750 m. Trophic level from prey numerical frequency was estimated at 4.4±0.46

Diretriz da Sociedade Brasileira de Cardiologia sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.  Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities.   Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.  The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.  The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.     Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.    Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.&nbsp

Experimental Study on Induction Heating Equipment Applied in Wireless Energy Transfer for Smart Grids

Part 17: Power ConversionInternational audienceThis work is focused on the design of the contactless energy transmitters and testing of their electrical parameters, varying the working frequency in the kHz range. The intended application is related to the possibility to make most efficient wireless charging of different batteries from the grid, guaranteeing more acceptable use of the electric vehicles

Analyzing Pilot Projects of Creative Tourism in an Ultra-Peripheral Region: Which Guidelines Can Be Extracted for Sustainable Regional Development?

Several authors have shown that some tourism typologies—i.e., rural tourism, nature-based tourism, or creative tourism—have a more predominant role in attaining regional sustainability. In this regard, this paper explores the impacts of five pilot projects of creative tourism on the sustainable development of the insular Autonomous Region of the Azores. Through direct exploratory tools, such as interviews and site analyses, the present study enabled us to provide greater insight into creative tourism projects and their relevance to the development of an ultra-peripheral island region. As part of the CREATOUR AZORES Project, this study is based on five creative tourism pilot projects operating in the Azores, Portugal. As such, it is recommended that the regional government, local authorities, and other relevant actors and players in this region actively support and create strategies to strengthen these projects (and similar initiatives) once they not only contribute to regional development and destination promotion but also promote much-desired sustainable development—once these kinds of tourism, in theory, and practice, counteract the dire effects of mass tourism

Diet of mid-Atlantic Sowerby’s beaked whales Mesoplodon bidens

Copyright © 2011 Elsevier Ltd. All rights reserved.The first mid-Atlantic diet of Mesoplodon beaked whales is presented, from ten Sowerby's Mesoplodon bidens stranded in the Azores region between 2002 and 2009. This doubles the worldwide number of stomachs sampled, and reveals new feeding habits for this species. The mean number of prey items per stomach was 85±89 (range: 12–238), with fish accounting for 99.3% and cephalopods contributing less than 1% of total prey. Fish otoliths from 15 families and cephalopod lower mandibles from three families were identified, representing 22 taxa. The diet consisted mainly of small mid-water fish, the most numerous being Diaphus sp., Lampanyctus sp. and Melamphaidae species. Myctophids were present in all stranded individuals, followed by Diretmidae, Melamphaidae and Opisthoproctus soleatus, while the remaining fish species were scarce or single occurrences. Consistency of diet in four different years reveals a divergence from all previous records in continental areas, where mainly neritic and shelf-break benthopelagic fish species have been reported. Mid-Atlantic Sowerby's beaked whales' showed dietary plasticity, feeding on the most abundant mid-water groups occurring between 0 and750 m. Trophic level from prey numerical frequency was estimated at 4.4±0.46