22 research outputs found

    Grains - a major source of sustainable protein for health

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    Cereal grains are the main dietary source of energy, carbohydrates, and plant proteins world-wide. Currently, only 41% of grains are used for human consumption, and up to 35% are used for animal feed. Cereals have been overlooked as a source of environmentally sustainable and healthy plant proteins and could play a major role in transitioning towards a more sustainable food system for healthy diets. Cereal plant proteins are of good nutritional quality, but lysine is often the limiting amino acid. When consumed as whole grains, cereals provide health-protecting components such as dietary fiber and phytochemicals. Shifting grain use from feed to traditional foods and conceptually new foods and ingredients could improve protein security and alleviate climate change. Rapid development of new grain-based food ingredients and use of grains in new food contexts, such as dairy replacements and meat analogues, could accelerate the transition. This review discusses recent developments and outlines future perspectives for cereal grain use

    XVII-XIX. Yüzyıllarda Osmanlı Dönemi Konut Mimarisinde İç Mekân Tavan Süslemelerine Genel Bir Bakış / A General Overview of Ceiling Decoration in the Interior Design in XVII-XIX. Ottoman Period Residential Architecture

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    Osmanlı Mimarisi, XIV. yüzyıldan XX. yüzyıl başlarına kadar uzanan geniş bir sürece yayılmaktadır. Türkiye Selçuklularını takiben gelen Osmanlı; Erken-Olgun (Klasik) ve Batılılaşma dönemi olmak üzere yüzyılları kapsayan zengin mimari eserler ortaya koymuştur. Mimari yapılarında sadece dış cephelerine değil iç mekân kurgusuna da önem veren Osmanlı Devleti, mimari yapılarını çeşitli malzeme ve teknikler kullanarak bezemelerle süslemiştir. Makalede, Erken-Olgun (Klasik) ve Batılılaşma dönemi ile Osmanlı sivil mimarlık unsurlarından konut mimarisi iç mekân dekorları yönünden tarihsel bir perspektifte incelenmekte olup, XVII.-XIX. yüzyıllara tarihlenen eserlerin iç mekân tasarımlarında tavan bezeme özellikleri ele alınmıştır. Çalışma kapsamında, mimari yapıların iç mekân tasarımlarındaki tavan düzenlemelerine yer verilmiş ve Köprülü Yalısı, Latifoğlu Konağı, Birgi Çakıroğlu Konağı ve Kavafyan Evi incelenmiştir. Bu incelemede, makale kapsamında ele alınmış olan Osmanlı konut mimarisinin iç mekân kurgusunda daha önceki yüzyıllarda uygulanmış, bilinirliği, kaydı ve ulaşılabilirliği olan tavan düzenlemeleri göz önünde bulundurulmuştur. / Apart Ottoman Architecture spreads over a long period from the XIV. century to the beginning of the XX. century. The Seljuks of Turkey followed by Ottomans revealed superb architectural works in Early-Mature (Classic) and Late period which covers centuries. The Ottoman Empire, which attaches importance not only the exterior facades but also the interior design of the architectural structures, adorned by using various materials and techniques. In the article, early-classical period and westernization period with residential architecture from elements of Ottoman civil architecture are examined in terms of the ceiling decoration characteristics of interior design of civil architectural structures dated to XVII.-XIX. centuries are presented. The study includes ceiling decorations and investigates which is the important part of interior design of architectural spaces and evaluates Köprülü Yalısı, Latifoğlu Mansion, Birgi Çakıroğlu Mansion and Kavafyan House. In this investigation, the ceiling decorations of interior design that have been implemented in previous centuries, known, had a record and accessible, have been taken into consideration from the scope of the interior design of the Ottoman residential architecture

    Obesity among patients with mood disorders

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    2nd Biennial Conference of the International-Society-for-Bipolar-Disorders -- AUG 02-04, 2006 -- Edinburgh, SCOTLANDWOS: 00023918630011

    Grains - a major source of sustainable protein for health

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    Cereal grains are the main dietary source of energy, carbohydrates, and plant proteins world-wide. Currently, only 41% of grains are used for human consumption, and up to 35% are used for animal feed. Cereals have been overlooked as a source of environmentally sustainable and healthy plant proteins and could play a major role in transitioning towards a more sustainable food system for healthy diets. Cereal plant proteins are of good nutritional quality, but lysine is often the limiting amino acid. When consumed as whole grains, cereals provide health-protecting components such as dietary fiber and phytochemicals. Shifting grain use from feed to traditional foods and conceptually new foods and ingredients could improve protein security and alleviate climate change. Rapid development of new grain-based food ingredients and use of grains in new food contexts, such as dairy replacements and meat analogues, could accelerate the transition. This review discusses recent developments and outlines future perspectives for cereal grain use

    Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.

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    CD8+ T cells impact control of viral infections by direct elimination of infected cells and secretion of a number of soluble factors. In HIV-1 infection, persistent HIV-1 specific IFN-gamma+ CD8+ T cell responses are detected in the setting of disease progression, consistent with functional impairment in vivo. Recent data suggest that impaired maturation, as defined by the lineage markers CD45RA and CCR7, may contribute to a lack of immune control by these responses.We investigated the maturation phenotype of epitope-specific CD8+ T cell responses directed against HIV-1 in 42 chronically infected, untreated individuals, 22 of whom were "Controllers" (median 1140 RNA copies/ml plasma, range<50 to 2520), and 20 "progressors" of whom had advanced disease and high viral loads (median 135,500 RNA copies/ml plasma, range 12100 to >750000). Evaluation of a mean of 5 epitopes per person revealed that terminally differentiated CD8+ T cells directed against HIV-1 are more often seen in HIV-1 Controllers (16/22; 73%) compared to HIV-1 progressors (7/20; 35%)(p = 0.015), but the maturation state of epitope-specific responses within a given individual was quite variable. Maturation phenotype was independent of the HLA restriction or the specificity of a given CD8+ T cell response and individual epitopes associated with slow disease progression were not more likely to be terminally differentiated.These data indicate that although full maturation of epitope-specific CD8+ T cell responses is associated with viral control, the maturation status of HIV-1 specific CD8+ T cell responses within a given individual are quite heterogeneous, suggesting epitope-specific influences on CD8+ T cell function
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