Modifiable risk factors associated with bronchiolitis

Background: We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases: median age: 2 months; age range: 0.5-12 months; boys: 55.4%) and 213 children aged <3 years (controls: median age: 12 months; age range: 0.5-36 months; boys: 54.5%) with a negative medical history for lower respiratory tract diseases hospitalized at 'Sapienza' University Rome and IRCCS Bambino Gesù Hospital. Infants' parents completed a standardized 53-item questionnaire seeking information on social-demographic and clinical characteristics, indoor pollution, eating habits and outdoor air pollution. Multivariate logistic regression analyses were run to assess the independent effect of risk factors, accounting for confounders and effect modifiers. Results: In the 213 hospitalized infants the questionnaire identified the following risk factors for acute bronchiolitis: breastfeeding 3/43 months (OR: 2.1, 95% confidence interval [CI]: 1.2-3.6), presence of older siblings (OR: 2.8, 95% CI: 1.7-4.7), 3/44 cohabitants (OR: 1.5, 95% CI: 1.1-2.1), and using seed oil for cooking (OR: 1.7, 95% CI: 1.2-2.6). Having renovated their home in the past 12 months and concurrently being exposed daily to smoking, involving more than 11 cigarettes and two or more smoking cohabitants, were more frequent factors in cases than in controls (p = 0.021 and 0.05), whereas self-estimated proximity to road and traffic was similar in the two groups. Conclusions: We identified several risk factors for acute bronchiolitis related to indoor and outdoor pollution, including inhaling cooking oil fumes. Having this information would help public health authorities draw up effective preventive measures - for example, teach mothers to avoid handling their child when they have a cold and eliminate exposure to second-hand tobacco smoke

Bronchiolitis – It Is Time for a Unique Definition

Bronchiolitis is the most common lower respiratory tract infections in infants. It is time to reach a unique clinical definition, encompassing the acute onset of respiratory distress with cough, tachypnoea, retraction and diffuse crackles on auscultation in infants aged less than 12 months

An Italian Multicenter Study on the Epidemiology of Respiratory Syncytial Virus During SARS-CoV-2 Pandemic in Hospitalized Children

Since the beginning of 2020, a remarkably low incidence of respiratory virus hospitalizations has been reported worldwide. We prospectively evaluated 587 children, aged &lt;12 years, admitted for respiratory tract infections from 1 September 2021 to 15 March 2022 in four Italian pediatric hospitals to assess the burden of respiratory viruses during the COVID-19 pandemic in Italy. At admission, a Clinical Respiratory Score was assigned and nasopharyngeal or nasal washing samples were collected and tested for respiratory viruses. Total admissions increased from the second half of October 2021 to the first half of December 2021 with a peak in early November 2021. The respiratory syncytial virus (RSV) incidence curve coincided with the total hospitalizations curve, occurred earlier than in the pre-pandemic years, and showed an opposite trend with respect to the incidence rate of SARS-CoV-2. Our results demonstrated an early peak in pediatric hospitalizations for RSV. SARS-CoV-2 may exhibit a competitive pressure on other respiratory viruses, most notably RSV

Determinants of adoption of biosecurity principles by poultry farmers in Kwara State, Nigeria

The study assessed the determinant factors influencing the adoption of biosecurity principles by poultry farmers in Kwara State, Nigeria. The major objective was to determine poultry farmer awareness and adoption of various biosecurity principles. A multistage sampling technique was used to select the respondents. Data for the study were collected from 92 respondents, through the use of structured questionnaire and interview schedule. Data were subjected to both descriptive and inferential statistic (Logit regression analysis). The results revealed that majority of the poultry farmers were still within their productive and active age (M=47years), majority were well educated (M=15years) and majority (60 %) reared both broilers and layers.  The study also showed that there was 100% awareness and trial of all the biosecurity principles under consideration The most adopted biosecurity principles with 100% adoption however, were provision of adequate ventilation, removal of dead birds, offering of good quality feed and water, vaccination and provision of proper medication. The result further revealed that respondents with larger number of birds (1.994), access to credit (1.715), frequent contact with extension agents (2.183) and access to training (2.083) had high propensity to adoption of biosecurity activities. The respondents perceived all the biosecurity principles under consideration as effective in preventing looses in their farms. They however, perceived the following constraints as severe constraints: inadequate capital (M=2.96), disease and parasites (M=2.97) and inadequate credit facility (M= 2.74). The study concludes that poultry farmers’ awareness of biosecurity activities was high, with moderate rate of adoption of the activities; they however, perceived biosecurity principles as effective means of preventing diseases infection.Keywords: Adoption, biosecurity principles, poultry, farmer

КУЛЬТУРНИЙ ФЕНОМЕН ЛЮДИНИ ПОГРАНИЧЧЯ. (The cultural phenomenon of human Borderland.)

У статті здійснюється спроба аналізу феномену людини, яка мешкає на Пограниччі: виокремлюються головні риси і ключові прояви, властиві цьому феноменові. Також аналізується явище кордону, проблематика діалогу культур і проблема ідентичності. (Article is an attempt to the phenomenon of people who live on the Borderland: singles out the main features and key manifestation of this peculiar phenomenon. Also examines the phenomenon of border issues dialogue of cultures and the problem of identity.

Update of the European paediatric respiratory medicine syllabus

The 10-year-old European syllabus for paediatric respiratory medicine (PRM; also known as paediatric pulmonology) was updated by a consensus-based method using an expert task force for redrafting, and a subsequent Delphi process to achieve consensus. There was a high degree of consensus for the final syllabus, which has been streamlined and made more relevant to current practice. All modules are now mandatory apart from the undertaking of research projects, which is optional. Although there are still a number of countries in Europe which do not recognise PRM as a separate subspecialty, there are paediatric respiratory physicians practising in every country in Europe, and a current and harmonised European syllabus in the subspecialty remains important for defining the training and areas of practice of PRM practitioners