Institutions and Policies Shaping Industrial Development: An Introductory Note

In this work, meant as an introduction to the contributions of the task force on Industrial Policies and Development, Initiative for Policy Dialogue, Columbia University, New York, we discuss the role of institutions and policies in the process of development. We begin by arguing how misleading the "market failure" language can be in order to assess the necessity of public policies in that it evaluates it against a yardstick that is hardly met by any observed market set-up. Much nearer to the empirical evidence we argue that even when one encounters a prevailing market form of governance of economic interactions, the latter are embedded in a rich thread of non-market institutions. This applies in general and is particularly so with respect to the production and use of information and technological knowledge. In this work we build on the fundamental institutional embeddedness of such processes of technological learning in both developed and catching-up countries and we try to identify some quite robust policy ingredients which have historically accompanied the co-evolution between technological capabilities, forms of corporate organisations and incentive structures. All experiences of successful catching-up and sometimes overtaking the incumbent economic leaders – starting with the USA vis-à-vis Britain – have involved “institution building” and policy measures affecting technological imitation, the organisations of industries, trade patterns and intellectual property rights. This is likely to apply today, too, – we argue – also in the context of a “globalised” world economy.Institutions, development, industrial policies, technological catching-up, trade specialisations.

University School Training Model Consultation Practica: Dismantling Anti-Black Racism with Predominately White Educators to Improve School, Family, Community Collaborations with Black Families and Community Stakeholders

This article outlines a consultation case study facilitated in an urban elementary school through the University School Training Model (USTM) (Colles et al., 2019; Morris et al., 2016). The USTM is a collaboration between an APA accredited Counseling Psychology doctoral program and an urban school district to provide racially responsive counseling and consulting services and graduate level training. The case study details a consultation practica to improve school, family, and community collaborations in an urban elementary school with predominantly Black stakeholders and a predominantly White female school staff. The introduction, background, and self-evaluation of the consultation process are reviewed. Project demographics, situation background, consultee role, and problem statement are then addressed. The goals, intervention grids, evaluation, termination, and post consultation follow-up are discussed. The transformative impact of consulting with urban school leaders to dismantle educational practices that uphold racism, white supremacy, and anti-Blackness that inhibit school, family, and community collaborations is highlighted

Comparative growth and static allometry in the genus Chlorocebus

Characterizing variation in growth across populations is critical to understanding multiple aspects of development in primates, including within-taxon developmental plasticity and the evolution of life history patterns. Growth in wild primates has often been reported and directly compared across larger taxonomic groups and within social groups, but comparisons are rarely investigated across widely dispersed populations of a single taxon. With the Vervet Phenome-Genome Project and the International Vervet Research Consortium, we trapped 936 vervet monkeys of all ages representing three populations (Kenyan pygerythrus, South African pygerythrus, and sabaeus from St. Kitts & Nevis). We gathered 10 different body measurements from each including mass, body breadth and length, segmental limb lengths, and chest circumference. To gain a better understanding of how ontogenetic patterns vary in these populations, we calculated bivariate allometry coefficients, derived using PCA on log-transformed and z-standardized trait values, and compared them to isometric vector coefficients. Within all population samples, around weaning age most traits showed a negative allometric relationship to body length. As each population ages, however, distinct patterns emerge, showing population differences in onset and intensity of growth among traits. In concordance with other analyses on growth in these populations, our results suggest that there exist relative differences in patterns of growth between Chlorocebus populations, further suggesting selection for unique developmental pathways in each

Calcium peroxide from ambient to high pressures.

Structures of calcium peroxide (CaO2) are investigated in the pressure range 0-200 GPa using the ab initio random structure searching (AIRSS) method and density functional theory (DFT) calculations. At 0 GPa, there are several CaO2 structures very close in enthalpy, with the ground-state structure dependent on the choice of exchange-correlation functional. Further stable structures for CaO2 with C2/c, I4/mcm and P21/c symmetries emerge at pressures below 40 GPa. These phases are thermodynamically stable against decomposition into CaO and O2. The stability of CaO2 with respect to decomposition increases with pressure, with peak stability occurring at the CaO B1-B2 phase transition at 65 GPa. Phonon calculations using the quasiharmonic approximation show that CaO2 is a stable oxide of calcium at mantle temperatures and pressures, highlighting a possible role for CaO2 in planetary geochemistry. We sketch the phase diagram for CaO2, and find at least five new stable phases in the pressure-temperature ranges 0 ≤ P ≤ 60 GPa, 0 ≤ T ≤ 600 K, including two new candidates for the zero-pressure ground state structure.Calculations were performed using the Darwin Supercomputer of the University of Cambridge High Performance Computing Service (http://www.hpc.cam.ac.uk/), as well as the ARCHER UK National Supercomputing Service (http://www.archer.ac.uk/). Financial support was provided by the Engineering and Physical Sciences Research Council (UK). JRN acknowledges the support of the Cambridge Commonwealth Trust.This is the final version of the article. It first appeared from Royal Society of Chemistry via http://dx.doi.org/10.1039/C4CP05644

Status of Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection and Remaining Challenges

PMC6446912Chronic infection with hepatitis C virus is a major cause of liver disease and hepatocellular carcinoma worldwide. After the discovery of hepatitis C virus 3 decades ago, the identification of the structure of the viral proteins, combined with high-throughput replicon models, enabled the discovery and development of direct-acting antivirals. These agents have revolutionized patient care, with cure rates of more than 90%. We review the status of direct-acting antiviral therapies for hepatitis C virus infection and discuss remaining challenges. We highlight licensed compounds, discuss the potential to shorten therapy even further, and review different options for treatment failure and resistance. We also provide an overview of clinical experience with generic agents and evidence for their efficacy. Finally, we discuss the need for new drugs and outline promising targets for future therapies

Laboratory studies of refractory metal oxide smokes

Studies of the properties of refractory metal oxide smokes condensed from a gas containing various combinations of SiH4, Fe(CO)5, Al(CH3)3, TiCl4, O2 and N2O in a hydrogen carrier stream at 500 K greater than T greater than 1500 K were performed. Ultraviolet, visible and infrared spectra of pure, amorphous SiO(x), FeO(x), AlO(x) and TiO(x) smokes are discussed, as well as the spectra of various co-condensed amorphous oxides, such as FE(x)SiO(y) or Fe(x)AlO(y). Preliminary studies of the changes induced in the infrared spectra of iron-containing oxide smokes by vacuum thermal annealing suggest that such materials become increasingly opaque in the near infrared with increased processing: hydration may have the opposite effect. More work on the processing of these materials is required to confirm such a trend: this work is currently in progress. Preliminary studies of the ultraviolet spectra of amorphous Si2O3 and MgSiO(x) smokes revealed no interesting features in the region from 200 to 300 nm. Studies of the ultraviolet spectra of both amorphous, hydrated and annealed SiO(x), TiO(x), AlO(x) and FeO(x) smokes are currently in progress. Finally, data on the oxygen isotopic composition of the smokes produced in the experiments are presented, which indicate that the oxygen becomes isotopically fractionated during grain condensation. Oxygen in the grains is as much as 3 percent per amu lighter than the oxygen in the original gas stream. The authors are currently conducting experiments to understand the mechanism by which fractionation occurs

Copy number variation in African Americans

<p>Abstract</p> <p>Background</p> <p>Copy number variants (CNVs) have been identified in several studies to be associated with complex diseases. It is important, therefore, to understand the distribution of CNVs within and among populations. This study is the first report of a CNV map in African Americans.</p> <p>Results</p> <p>Employing a SNP platform with greater than 500,000 SNPs, a first-generation CNV map of the African American genome was generated using DNA from 385 healthy African American individuals, and compared to a sample of 435 healthy White individuals. A total of 1362 CNVs were identified within African Americans, which included two CNV regions that were significantly different in frequency between African Americans and Whites (17q21 and 15q11). In addition, a duplication was identified in 74% of DNAs derived from cell lines that was not present in any of the whole blood derived DNAs.</p> <p>Conclusion</p> <p>The Affymetrix 500 K array provides reliable CNV mapping information. However, using cell lines as a source of DNA may introduce artifacts. The duplication identified in high frequency in Whites and low frequency in African Americans on chromosome 17q21 reflects haplotype specific frequency differences between ancestral groups. The generation of the CNV map will be a valuable tool for identifying disease associated CNVs in African Americans.</p

Organizational factors and total quality management - an empirical study

The level of awareness of Total Quality Management (TQM) has increased considerably over the last few years. Different sets of organizational requirements are prescribed by quality management gurus and practitioners for the effective practice of TQM. These requirements do not seem to have been formulated on the basis of systematic empirical research. Many researchers point out that tacit factors, e.g. employee empowerment, open culture and executive commitment, and not TQM tools and techniques alone, could drive TQM success, and that organizations would need to acquire these factors to stay successful. Many TQM advocates have also suggested that a conducive organizational environment would be essential for an effective practice of TQM. However, they did not offer any empirical evidence. There appears to be no empirical study reported in the literature that could establish a relation between TQM and organizational factors. The objective of this paper is to describe an empirical research on TQM conducted in Indian business units carried out recently by considering some organizational factors, e.g. quality of work life, organizational climate and communication. The methodology and findings are discussed in detail

Elastic Instability of a Crystal Growing on a Curved Surface

Although the effects of kinetics on crystal growth are well understood, the role of substrate curvature is not yet established. We studied rigid, two-dimensional colloidal crystals growing on spherical droplets to understand how the elastic stress induced by Gaussian curvature affects the growth pathway. In contrast to crystals grown on flat surfaces or compliant crystals on droplets, these crystals formed branched, ribbon-like domains with large voids and no topological defects. We show that this morphology minimizes the curvature-induced elastic energy. Our results illustrate the effects of curvature on the ubiquitous process of crystallization, with practical implications for nanoscale disorder-order transitions on curved manifolds, including the assembly of viral capsids, phase separation on vesicles, and crystallization of tetrahedra in three dimensions.Engineering and Applied SciencesPhysic

A revision of the South American snake genus Thamnodynastes Wagler, 1830 (Serpentes, Colubridae, Tachymenini): I. Two new species of Thamnodynastes from Central Brazil and adjacent areas, with a redefinition of and neotype designation for Thamnodynastes pallidus (Linnaeus, 1758)

Two new species of Thamnodynastes whose ranges are entirely or largely in Brazil are described. Thamnodynastes pallidus, one of the most easily identified species of the genus, is redefined and a neotype is designated, and Coluber strigilis Thunberg is placed in its synonymy, thus clarifying an enduring state of confusion in the taxonomy of this genus