2,283 research outputs found
Comparing anomaly detection methods in computer networks
This work in progress outlines a comparison of anomaly detection methods that we are undertaking. We are comparing different types of anomaly detection methods with the purpose of achieving results covering a broad spectrum of anomalies. We also outline the datasets that we will be using and the metrics that we will use for our evaluation
Biomarker and Translational Prostate Cancer Research
The existing clinical biomarkers for prostate cancer (PCa) are not ideal, since they cannot specifically differentiate between those patients who should be treated immediately and those who should avoid overtreatment. Current screening techniques lack specificity, and a decisive diagnosis of PCa is based on prostate biopsy. Although PCa screening is widely utilized nowadays, two-thirds of the biopsies performed are still unnecessary. Thus, the discovery of noninvasive PCa biomarkers remains an urgent unmet medical need. Once metastasized, there is still no curative therapy. A better understanding of sustained androgen receptor signalling in castration resistant prostate cancer (CRPC) has now led to the development of more effective therapies. We need a better understanding of the molecular and cellular aspects of prostate carcinogenesis and progression. Identification of cancer initiating cells and therapies against these populations is a promising way forward to fight this disease
The use of abstraction concepts for representing and structuring documents
Due to the amount of documents available in modern offices, it is necessary to provide a multitude of methods for the structuring of knowledge, i.e., abstraction concepts. In order to achieve their uniform representation, such concepts should be considered in an integrated fashion to allow concise descriptions free of redundancy. In this paper, we present our approach towards an integration of methods of knowledge structuring. For this purpose, our view of abstraction concepts is briefly introduced using examples of the document world and compared with some existing systems. The main focus of this paper is to show the applicability of an integration of these abstraction concepts as well as their built-in reasoning facilities in supporting document processing and management
Integration of document representation, processing and management
This paper describes a way for document representation and proposes an approach towards an integrated document processing and management system. The approach has the intention to capture essentially freely structured documents, like those typically used in the office domain. The document analysis system ANASTASIL is capable to reveal the structure of complex paper documents, as well as logical objects within it, like receiver, footnote, date. Moreover, it facilitates the handling of the containing information. Analyzed documents are stored by the management system KRISYS that is connected to several different subsequent services. The described integrated system can be considered as an ideal extension of the human clerk, making his tasks in information processing easier. The symbolic representation of the analysis results allow an easy transformation in a given international standard, e.g., ODA/ODIF or SGML, and to interchange it via global network
Approximating the least core value and least core of cooperative games with supermodular costs
We study the approximation of the least core value and the least core of supermodular cost cooperative games. We provide a framework for approximation based on oracles that approximately determine maximally violated constraints. This framework yields a 3-approximation algorithm for computing the least core value of supermodular cost cooperative games, and a polynomial-time algorithm for computing a cost allocation in the 2-approximate least core of these games. This approximation framework extends naturally to submodular profit cooperative games. For scheduling games, a special class of supermodular cost cooperative games, we give a fully polynomial-time approximation scheme for computing the least core value. For matroid profit games, a special class of submodular profit cooperative games, we give exact polynomial-time algorithms for computing the least core value as well as a least core cost allocation.National Science Foundation (U.S.) (DMI-0426686
Analisis Faktor-faktor yang Mempengaruhi Harga Cabai Merah di Kota Manado Provinsi Sulawesi Utara Menggunakan Analisis Regresi Linear Berganda
Cabai merupakan tanaman yang di butuhkan di masyarakat Indonesia baik sebagai bahan penyedap masakan, tanaman kesehatan, bahkan sebagai mata pencaharian, selain itu cabai merah memiliki nilai gizi yang cukup tinggi, dan juga mempunyai nilai ekonomi tinggi. Tujuan penelitian ini untuk mengetahui faktor-faktor yang mempengaruhi harga cabai merah di Kota Manado Provinsi Sulawesi Utara menggunakan Analisis Regresi Linear Berganda. Data yang digunakan adalah data sekunder yang diperoleh dari Badan Pusat Statistik Sulawesi Utara dengan data berupa harga cabai per bulan di Kota Manado periode tahun 2020-2022. Variabel yang digunakan dalam penelitian ini adalah produksi , luas lahan , curah hujan , dan inflasi . Hasil penelitian ini didapatkan model regresi linear berganda dan menunjukkan bahwa secara parsial luas lahan dan inflasi berpengaruh positif terhadap harga cabai merah. Secara simultan produksi , luas lahan , curah hujan , dan inflasi berpengaruh terhadap harga cabai merah di Kota Manado Provinsi Sulawesi Utara.
Chili is a plant that is needed in Indonesian society both as a food flavoring ingredient, a health plant, even as a livelihood. Besides that, red chili has quite high nutritional value, and also has high economic value. The purpose of this study was to determine the factors that influence the price of red chili in Manado City, North Sulawesi Province using Multiple Linear Regression Analysis. The data used is secondary data obtained from the Central Bureau of Statistics of North Sulawesi with a lot of data per month in Manado City for the 2020-2022 period. The variable used in this research is production , land area , rainfall , inflation . The results of this study obtained a multiple linear regression model and show that partially land area and inflation positive effect on the price of red chili. Simultaneous production , land area , rainfall , and inflation effect on the price of red chili in Manado City, North Sulawesi Province
Influence of coral and algal exudates on microbially mediated reef metabolism.
Benthic primary producers in tropical reef ecosystems can alter biogeochemical cycling and microbial processes in the surrounding seawater. In order to quantify these influences, we measured rates of photosynthesis, respiration, and dissolved organic carbon (DOC) exudate release by the dominant benthic primary producers (calcifying and non-calcifying macroalgae, turf-algae and corals) on reefs of Mo'orea French Polynesia. Subsequently, we examined planktonic and benthic microbial community response to these dissolved exudates by measuring bacterial growth rates and oxygen and DOC fluxes in dark and daylight incubation experiments. All benthic primary producers exuded significant quantities of DOC (roughly 10% of their daily fixed carbon) into the surrounding water over a diurnal cycle. The microbial community responses were dependent upon the source of the exudates and whether the inoculum of microbes included planktonic or planktonic plus benthic communities. The planktonic and benthic microbial communities in the unamended control treatments exhibited opposing influences on DO concentration where respiration dominated in treatments comprised solely of plankton and autotrophy dominated in treatments with benthic plus plankon microbial communities. Coral exudates (and associated inorganic nutrients) caused a shift towards a net autotrophic microbial metabolism by increasing the net production of oxygen by the benthic and decreasing the net consumption of oxygen by the planktonic microbial community. In contrast, the addition of algal exudates decreased the net primary production by the benthic communities and increased the net consumption of oxygen by the planktonic microbial community thereby resulting in a shift towards net heterotrophic community metabolism. When scaled up to the reef habitat, exudate-induced effects on microbial respiration did not outweigh the high oxygen production rates of benthic algae, such that reef areas dominated with benthic primary producers were always estimated to be net autotrophic. However, estimates of microbial consumption of DOC at the reef scale surpassed the DOC exudation rates suggesting net consumption of DOC at the reef-scale. In situ mesocosm experiments using custom-made benthic chambers placed over different types of benthic communities exhibited identical trends to those found in incubation experiments. Here we provide the first comprehensive dataset examining direct primary producer-induced, and indirect microbially mediated alterations of elemental cycling in both benthic and planktonic reef environments over diurnal cycles. Our results highlight the variability of the influence of different benthic primary producers on microbial metabolism in reef ecosystems and the potential implications for energy transfer to higher trophic levels during shifts from coral to algal dominance on reefs
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