427 research outputs found
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Complete Genome Sequence of the Citrobacter freundii Type Strain.
Citrobacter freundii is a species of facultative anaerobic Gram-negative bacteria of the family Enterobacteriaceae The complete genome is composed of a single chromosomal circle of 4,957,773 bp with a G+C content of 52%
Observation of String Breaking in QCD
We numerically investigate the transition of the static quark-antiquark
string into a static-light meson-antimeson system. Improving noise reduction
techniques, we are able to resolve the signature of string breaking dynamics
for n_f=2 lattice QCD at zero temperature. This result can be related to
properties of quarkonium systems. We also study short-distance interactions
between two static-light mesons.Comment: 27 pages, 22 figures, changed decimal place of errors in 3 entries of
Table, corrected reference
Wnt signaling in granulosa cell tumors of the ovary
Granulosa cell tumors (GCT), a malignant type of sex-cord stromal tumor, account for approximately 2-5% of all ovarian malignancies. They are often identified before they have spread beyond the ovary, but advanced disease can be quite challenging to treat. Wnt signaling has been suggested to contribute to the formation of GCT. We hypothesized Wnt signaling was involved in human GCT
1975 Clinic Yearbook
The Clinic is the yearbook of the Sidney Kimmel Medical College (formerly Jefferson Medical College) at Thomas Jefferson University
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Chloride channels regulate differentiation and barrier functions of the mammalian airway.
The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction leads to early onset airway diseases, remain unclear. In this study, we systematically characterized the developmental landscape of the mouse airway using single-cell RNA sequencing and identified remarkably conserved cellular programs operating during human fetal development. We demonstrated that in mouse, genetic inactivation of chloride channel Ano1/Tmem16a compromises airway barrier function, results in early signs of inflammation, and alters the airway cellular landscape by depleting epithelial progenitors. Mouse Ano1-/-mutants exhibited mucus obstruction and abnormal mucociliary clearance that resemble the airway defects associated with cystic fibrosis. The data reveal critical and non-redundant roles for Ano1 in organogenesis, and show that chloride channels are essential for mammalian airway formation and function
On the low fermionic eigenmode dominance in QCD on the lattice
We demonstrate the utility of a spectral approximation to fermion loop
operators using low-lying eigenmodes of the hermitian Dirac-Wilson matrix, Q.
The investigation is based on a total of 400 full QCD vacuum configurations,
with two degenerate flavors of dynamical Wilson fermions at beta =5.6, at two
different sea quark masses. The spectral approach is highly competitive for
accessing both topological charge and disconnected diagrams, on large lattices
and small quark masses. We propose suitable partial summation techniques that
provide sufficient saturation for estimating Tr Q^{-1}, which is related to the
topological charge. In the effective mass plot of the eta' meson we achieved a
consistent early plateau formation, by ground state projecting the connected
piece of its propagator.Comment: 15 pages, 25 figures, citations adde
Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations
Zmiz1 staining is elevated in patients with epithelial ovarian cancer. Tumors that are Zmiz1 positive are associated with mutations of the p53 gene. Zmiz1 overexpression may be associated with decreased survival in patients with epithelial ovarian cancer. Additional studies are needed to more clearly determine the role of Zmiz1 in patients with epithelial ovarian cancer
Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations
Zmiz1 staining is elevated in patients with epithelial ovarian cancer. Tumors that are Zmiz1 positive are associated with mutations of the p53 gene. Zmiz1 overexpression may be associated with decreased survival in patients with epithelial ovarian cancer. Additional studies are needed to more clearly determine the role of Zmiz1 in patients with epithelial ovarian cancer
Nitrogen Production in Starburst Galaxies Detected by GALEX
We investigate the production of nitrogen in star-forming galaxies with ultraviolet (UV) radiation detected by the Galaxy Evolution Explorer Satellite (GALEX). We use a sample of 8745 GALEX emission-line galaxies matched to the Sloan Digital Sky Survey (SDSS) spectroscopic sample. We derive both gas-phase oxygen and nitrogen abundances for the sample and apply stellar population synthesis models to derive stellar masses and star formation histories of the galaxies. We compare oxygen abundances derived using three different diagnostics. We derive the specific star formation rates of the galaxies by modeling the seven-band GALEX+SDSS photometry. We find that galaxies that have log (SFR/M_*) ≳ − 10.0 typically have values of log (N/O) ~ 0.05 dex less than galaxies with log (SFR/M_*) ≾ − 10.0 and similar oxygen abundances
HQET at order : II. Spectroscopy in the quenched approximation
Using Heavy Quark Effective Theory with non-perturbatively determined
parameters in a quenched lattice calculation, we evaluate the splittings
between the ground state and the first two radially excited states of the
system at static order. We also determine the splitting between first excited
and ground state, and between the and ground states to order
. The Generalized Eigenvalue Problem and the use of all-to-all
propagators are important ingredients of our approach.Comment: (1+18) pages, 3 figures (4 pdf files); pdflatex; v2: corrections to
table 1, results unaffecte
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