1,524 research outputs found
Electromagnetic Calorimeter Calibration with
Several methods can be used in order to achieve precise calibration of the LHCb Electromagnetic Calorimeter (ECAL) once reasonable cell equalization has been reached. At low transverse energy, the standard calibration procedure is an iterative method based on the fit of the invariant mass distribution for each cell of the decay with resolved photons. A new technique for generating the combinatorial background of such decays directly from data has been developed. Knowledge of the background could allow an alternative calibration method based on a event by event fit of the same invariant mass distribution where contributions from groups of cells are considered in a single fit. The background generation procedure and this possible new calibration method are presented in this poster, in addition to an overview of the LHCb Calorimetry system and ECAL calibration techniques
Descent of Equivalences and Character Bijections
Categorical equivalences between block algebras of finite groups—such as Morita and derived equivalences—are well known to induce character bijections which commute with the Galois groups of field extensions. This is the motivation for attempting to realise known Morita and derived equivalences over non-splitting fields. This article presents various results on the theme of descent to appropriate subfields and subrings. We start with the observation that perfect isometries induced by a virtual Morita equivalence induce isomorphisms of centres in non-split situations and explain connections with Navarro’s generalisation of the Alperin–McKay conjecture. We show that Rouquier’s splendid Rickard complex for blocks with cyclic defect groups descends to the non-split case. We also prove a descent theorem for Morita equivalences with endopermutation source
Coping Strategies in Male Patients under Treatment for Substance Use Disorders and/or Severe Mental Illness: Influence in Clinical Course at One-Year Follow-Up
Coping strategies have an impact on substance use disorders (SUD), relapses, and clinical variables, but knowledge on this area is scarce. We explored the coping strategies used during treatment in patients with dual diagnosis (DD), SUD, and severe mental illness (SMI), and the relation with clinical course and relapses at one-year follow-up. A sample of 223 patients was divided into three groups depending on diagnosis: DD (N = 80; SUD with comorbid schizophrenia or major depressive disorder), SUD only (N = 80), and SMI only (N = 63; schizophrenia or major depressive disorder). MANCOVA analyses reflected differences in self-criticism and problem avoidance, with a higher use of these in the DD and SUD groups. The coping strategies used differed depending on the presence/absence of a SUD, but not depending on psychiatric diagnosis. At one-year follow-up, social support was the only strategy that predicted the presence of relapses in DD patients with schizophrenia (positively), and in SMI patients with major depressive disorder (negatively). Thus, social support was associated with relapses, but the relationship was different depending on psychiatric diagnosis. Further studies should analyze the implications of social support as a coping strategy in different mental disorders, as well as its usefulness in individualized interventions
MicroRNAs expression, chromosomal alterations and immunoglobulin variable Heavy chain hypermutations in Mantle Cell Lymphomas
The contribution of microRNAs (miR) to the pathogenesis of mantle cell lymphoma (MCL) is not well known.We investigated
the expression of 86 mature miRs mapped to frequently altered genomic regions in MCL in CD5+/CD5 normal B cells, reactive
lymph nodes, and purified tumor cells of 17 leukemic MCL, 12 nodal MCL, and 8MCL cell lines. Genomic alterations of the
tumors were studied by single nucleotide polymorphism arrays
and comparative genomic hybridization. Leukemic and nodal
tumors showed a high number of differentially expressed miRs
compared with purified normal B cells, but only some of them
were commonly deregulated in both tumor types. An unsupervised
analysis of miR expression profile in purified leukemic
MCL cells revealed two clusters of tumors characterized by
different mutational status of the immunoglobulin genes,
proliferation signature, and number of genomic alterations.
The expression of most miRs was not related to copy number
changes in their respective chromosomal loci. Only the levels
of miRs included in the miR-17-92 cluster were significantly
related to genetic alterations at 13q31. Moreover, overexpression
of miR-17-5p/miR-20a from this cluster was associated
with high MYC mRNA levels in tumors with a more aggressive
behavior. In conclusion, the miR expression pattern of MCL is
deregulated in comparison with normal lymphoid cells and
distinguishes two subgroups of tumors with different biological
features.Postprint (updated version
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The structure of blocks with a Klein four defect group
We prove Erdmann’s conjecture [16] stating that every block with a Klein four defect group has a simple module with trivial source, and deduce from this that Puig’s finiteness conjecture holds for source algebras of blocks with a Klein four defect group. The proof uses the classification of finite simple groups
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