57 research outputs found
Background music changes the policy of human decision-making:Evidence from experimental and drift-diffusion model-based approaches on different decision tasks
The first Frontier Fields cluster: 4.5{\mu}m excess in a z~8 galaxy candidate in Abell 2744
We present in this letter the first analysis of a z~8 galaxy candidate found
in the Hubble and Spitzer imaging data of Abell 2744, as part of the Hubble
Frontier Fields legacy program. We applied the most commonly-used methods to
select exceptionally high-z galaxies by combining non-detection and
color-criteria using seven HST bands. We used GALFIT on IRAC images for fitting
and subtracting contamination of bright nearby sources. The physical properties
have been inferred from SED-fitting using templates with and without nebular
emission. This letter is focussed on the brightest candidate we found
(m=26.2) over the 4.9 arcmin field of view covered by the WFC3.
It shows a non-detection in the ACS bands and at 3.6{\mu}m whereas it is
clearly detected at 4.5{\mu}m with rather similar depths. This break in the
IRAC data could be explained by strong [OIII]+H{\beta} lines at z~8 which
contribute to the 4.5{\mu}m photometry. The best photo-z is found at
z~8.0, although solutions at low-redshift (z~1.9) cannot be
completely excluded, but they are strongly disfavoured by the SED-fitting work.
The amplification factor is relatively small at {\mu}=1.490.02. The Star
Formation Rate in this object is ranging from 8 to 60 Mo/yr, the stellar mass
is in the order of M=(2.5-10) x 10Mo and the size is
r~0.350.15 kpc. This object is one of the first z~8 LBG candidates showing
a clear break between 3.6{\mu}m and 4.5{\mu}m which is consistent with the IRAC
properties of the first spectroscopically confirmed galaxy at a similar
redshift. Due to its brightness, the redshift of this object could potentially
be confirmed by near infrared spectroscopy with current 8-10m telescopes. The
nature of this candidate will be revealed in the coming months with the arrival
of new ACS and Spitzer data, increasing the depth at optical and near-IR
wavelengths.Comment: 4 pages, 2 figures, Accepted for publication in Astronomy and
Astrophysics Letter
A specific insertion of a solo-LTR characterizes the Y-chromosome of Bryonia dioica (Cucurbitaceae)
Background: Relatively few species of flowering plants are dioecious and even fewer are known to have sex chromosomes. Current theory posits that homomorphic sex chromosomes, such as found in Bryonia dioica (Cucurbitaceae), offer insight into the early stages in the evolution of sex chromosomes from autosomes. Little is known about these early steps, but an accumulation of transposable element sequences has been observed on the Ychromosomes of some species with heteromorphic sex chromosomes. Recombination, by which transposable elements are removed, is suppressed on at least part of the emerging Y-chromosome, and this may explain the correlation between the emergence of sex chromosomes and transposable element enrichment.
Findings: We sequenced 2321 bp of the Y-chromosome in Bryonia dioica that flank a male-linked marker, BdY1, reported previously. Within this region, which should be suppressed for recombination, we observed a solo-LTR nested in a Copia-like transposable element. We also found other, presumably paralogous, solo-LTRs in a consensus sequence of the underlying Copia-like transposable element.
Conclusions: Given that solo-LTRs arise via recombination events, it is noteworthy that we find one in a genomic region where recombination should be suppressed. Although the solo-LTR could have arisen before recombination was suppressed, creating the male-linked marker BdY1, our previous study on B. dioica suggested that BdY1 may not lie in the recombination-suppressed region of the Y-chromosome in all populations. Presence of a solo-LTR near BdY1 therefore fits with the observed correlation between retrotransposon accumulation and the suppression of recombination early in the evolution of sex chromosomes. These findings further suggest that the homomorphic sex chromosomes of B. dioica, the first organism for which genetic XY sex-determination was inferred, are evolutionarily young and offer reference information for comparative studies of other plant sex chromosomes
Transcranial alternating current stimulation (tACS) at 40 Hz enhances face and object perception
Neurophysiological evidence suggests that face and object recognition relies on the coordinated activity of neural populations (i.e., neural oscillations) in the gamma-band range (> 30 Hz) over the occipito-temporal cortex. To test the causal effect of gamma-band oscillations on face and object perception we applied transcranial Alternating Current Stimulation (tACS) in healthy volunteers (N = 60). In this single-blind, sham-controlled study, we examined whether the administration of offline tACS at gamma-frequency (40 Hz) over the right occipital cortex enhances performance of perception and memory of face and object stimuli. We hypothesized that gamma tACS would enhance the perception of both categories of visual stimuli. Results, in line with our hypothesis, show that 40 Hz tACS enhanced both face and object perception. This effect is process-specific (i.e., it does not affect memory), frequency-specific (i.e., stimulation at 5 Hz did not cause any behavioural change), and site-specific (i.e., stimulation of the sensory-motor cortex did not affect performance). Our findings show that high-frequency tACS modulates human visual perception, and it is in line with neurophysiological studies showing that the perception of visual stimuli (i.e., faces and objects) is mediated by oscillations in the gamma-band range. Furthermore, this study adds insight about the design of effective neuromodulation protocols that might have implications for interventions in clinical settings
Role of deficits in pathogen recognition receptors in infection susceptibility
This work was supported by the
Northern Portugal Regional Operational Programme
(NORTE 2020), under the Portugal 2020 Partnership
Agreement, through the European Regional Development
Fund (FEDER) (NORTE-01-0145-FEDER-000013), and
the Fundação para a Ciência e Tecnologia (FCT)
(IF/00735/2014 to A.C. and SFRH/BPD/96176/2013 to
C.C.
Estimativa da produção de proteína microbiana pelos derivados de purinas na urina em novilhos
Produção de proteína microbiana e estimativas das excreções de derivados de purinas e de uréia em vacas lactantes alimentadas com rações isoprotéicas contendo diferentes níveis de compostos nitrogenados não-protéicos
Sex Determination:Why So Many Ways of Doing It?
Sexual reproduction is an ancient feature of life on earth, and the familiar X and Y chromosomes in humans and other model species have led to the impression that sex determination mechanisms are old and conserved. In fact, males and females are determined by diverse mechanisms that evolve rapidly in many taxa. Yet this diversity in primary sex-determining signals is coupled with conserved molecular pathways that trigger male or female development. Conflicting selection on different parts of the genome and on the two sexes may drive many of these transitions, but few systems with rapid turnover of sex determination mechanisms have been rigorously studied. Here we survey our current understanding of how and why sex determination evolves in animals and plants and identify important gaps in our knowledge that present exciting research opportunities to characterize the evolutionary forces and molecular pathways underlying the evolution of sex determination
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