747 research outputs found
Communication intentionnelle dans le domaine du leadership
L’existence de toute organisation repose sur le soutien que lui accordent ses membres. Le fonctionnement optimal d’un système est tributaire de la qualité des relations entre ses composantes, c’est-à -dire, pour une organisation, entre ses différents paliers. La qualité de ces relations présente des avantages concurrentiels sur les plans économique, politique et social, car elles se traduisent par une communication claire, directe et régulière entre les niveaux hiérarchiques. Pour les dirigeants, il s’agit de leur capacité à exercer leur leadership. Cette communication a un impact sur le développement des compétences des employés, la productivité de l’entreprise et sa visibilité stratégique dans la sphère politique et, enfin, sur l’attraction et le maintien d’une main-d’œuvre qualifiée et engagée. Il va sans dire qu’au 21e siècle, l’avènement des médias sociaux rend plus délicate la tâche des gestionnaires et présente ainsi un défi bien plus important que la mise en place de bonnes relations de travail qu’on préconisait au siècle dernier. Les auteurs aborderont le leadership autoral comme alternative en vue d’un leadership de conscience plus adapté aux défis des organisations du siècle actuel
A ociosidade e a subutilização de áreas servidas de infraestutura: análise dos instrumentos urbanÃsticos e a regulamentação no Plano Diretor de Biguaçu/SC
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Filosofia e Ciências Humanas. GeografiaO presente estudo tem como objetivo realizar um levantamento dos instrumentos urbanÃsticos previstos na Lei Federal nº 10.257/2001, denominada Estatuto da Cidade, a qual faculta aos gestores municipais as diretrizes na elaboração do Plano Diretor Municipal, que fazem referência aos critérios de expansão e à s estratégias de planejamento e gestão do desenvolvimento urbano que visam evitar a ociosidade e a subutilização de áreas servidas de infraestrutura, e que, sendo assim, não cumprem sua função social, e contrapô-los com os instrumentos atualmente regulamentados no Plano Diretor Municipal de Biguaçu/SC. Esta análise se dará sob um recorte espacial composto pelo conjunto de 12 lotes, totalizando uma área de aproximadamente 610.500m², os quais, até então, encontram-se inutilizados (baldios), no perÃodo entre os anos de 2003 a 2018. Sua localização se dá na região central do municÃpio de Biguaçu/SC, à s margens da BR 101 Km 195
Extending awareness of healthcare ethics at Cabrini Health: Junior clinicians\u27 perspectives
As Catholic healthcare organizations form a substantive part of healthcare delivery in the USA and Australia, ethical standards for Catholic health care were developed to guide practice. This study examined junior staff’s understanding of Catholic ethics. Using a qualitative descriptive design, we recruited 22 medical and nursing staff to interviews/focus groups. Though Catholic ethics seldom informed ethical approaches, the principles were acknowledged as being useful to support development of confident and respectful care approaches. Findings provide early insights into challenges faced in considering implementation of ethical codes across both secular and religious healthcare organizations, suggesting that a more creative and pastoral approach to dialoguing and implementing Catholic ethics is required
Correlação entre sinais clÃnicos da conjuntivite felina e a detecção molecular de felid herpesvirus-1, feline calicivirus, chlamydophila felis e mycoplasma felis em gatos de abrigos no Rio de Janeiro
Objectives: To perform molecular diagnosis of microbial agents (FHV-1, FCV, Mycoplasma felis, and Chlamydophila felis) in kittens with conjunctivitis and correlate the clinical signs with clinical severity. Material and Methods: A total of 108 conjunctival swab were collected from kittens without (G1; n = 40) and with (G2; n = 68) clinical signs of conjunctivitis. Animals from G2 group were scored from 1 (mild) to 4 (severe) according to the severity of conjunctivitis. All samples were submitted to PCR and RT-PCR. Results: FHV-1 was detected in 62/108 (57.4%) of samples, FCV in 40/108 (37.0%), M. felis in 11/108 (10.2%) and C. felis in 26/108 (24.1%). Mixed infections were detected in 39/108 (36.1%). In G1, 28/40 (70.0%) were positive for one or more agents, in G2, 58/68 (85.3%) were positive (P = 0.03). In 1, single infections by FHV-1were found in 21/40 (52.5%) samples, FCV in 2/40 (5.0%), C. felis in 1/40 (2.5%), and no pathogens were detected in 12/40 (30%) of samples, while mixed infections accounted for 29/40 (72.5%) of the cases. In G2, single FHV-1 infections were found in 31/68 (45.6%) samples, FCV in 10/68 (14.7 %), M. felis in 2/68 (3.0%) and C. felis also in 2/68 (3.0%), and no pathogens were detected in 10/68 (14.7%) samples, while mixed infections accounted for 36/68 (52.0%) of the cases. They were categorized as grade 1, 20/68 (29.4%), grade 2, 14/68 (20.6%), grade 3, 21/68 (30.9%) and grade 4, 13/68 (19.1%). The presence of FHV-1 and FCV is equally distributed among the four categories. More severe clinical signs, scores 3 and 4, are related to coinfections by C. felis and M. felis. Conclusions: FHV-1, FCV, C. felis and M. felis were identified in feline conjunctivitis. Co-infections are related to more severe cases of conjunctivitis. Molecular diagnosis is helpful to detect asymptomatic carriers and is a rapid and accurate method to determine the pathogen of feline conjunctivitis.O objetivo deste estudo foi realizar diagnóstico molecular de agentes microbiológicos (FHV-1, FCV, Mycoplasma felis e Chlamydophila felis) em gatos filhotes e associar a presença dos patógenos à gravidade dos sinais clÃnicos de conjuntivite. Foram coletadas um total de 108 amostras de suabe conjuntival de filhotes felinos assintomáticos (G1; n = 40) e sintomáticos (G2; n = 68). Animais do G2 foram categorizados de 1 (leve) até 4 (grave), de acordo com o quadro clÃnico de conjuntivite. As 108 amostras foram submetidas à PCR e RT-PCR. O FHV-1 foi detectado em 57,4% das amostras, o FCV em 37%, o M. felis em 10,2% e o C. felis em 24,1%. Coinfecções, por sua vez, foram detectadas em 36,1%. No G1, 70% das amostras foram positivas para um ou mais patógenos. No G2, 85,3% apresentavam infecções (P = 0,03). No G1, monoinfecções por FHV-1 foram diagnosticadas em 52,5% das amostras, por FCV em 5%, por C. felis em 2,5%, e em 30% das amostras analisadas nenhum dos patógenos estudados foi encontrado. Coinfecções, por sua vez, estavam presentes em 72,5% das amostras. No G2, monoinfecções por FHV-1 foram encontradas em 45,6% das amostras, por FCV em 14,7 %, por M. felis em 3% e por C. felis também em 3%. Nenhum dos patógenos estudados foi encontrado em 14,7% das amostras analisadas. Coinfecções, responsáveis por 52% dos casos, foram categorizados como Grau 1 (29,4%), Grau 2 (20,6%), Grau 3 (30,9%) e Grau 4 (19,1%). A presença de FHV-1 e FCV está igualmente distribuÃda entre as quatro categorias. Os sinais clÃnicos mais graves (graus 3 e 4) estão relacionados a coinfecções por C. felis e M. felis. Os agentes microbiológicos FHV-1, FCV, C. felis e M. felis foram encontrados em animais com conjuntivite. Coinfecções estão relacionadas aos casos mais graves. Por fim, concluiu-se que o diagnóstico molecular, além de detectar portadores assintomáticos, é um método rápido e acurado para o diagnóstico do patógeno causador da conjuntivite felina
Patients’ and caregivers’ contested perspectives on spiritual care for those affected by advanced illnesses: A qualitative descriptive study
Context; Spiritual care refers to practices and rituals addressing spiritual/religious concerns. It supports coping with loss and finding hope, meaning, and peace. Although integral to palliative care, its implementation is challenging.
Objective: To understand an Australian cohort of patients’ and caregivers’ perspectives about experiencing and optimizing spiritual care in the context of advanced illness.
Methods: Patients and caregivers of patients with #12 month prognosis were recruited from a broader spiritual study via criterion sampling and agreed to opt-in interviews. Participants from an Australian, metropolitan health service received a spiritual care definition and were interviewed. Transcripts were analyzed using qualitative description.
Results: 30 patients (17 male; mean age 70 years) and 10 caregivers (six male; mean age 58.9 years) participated. 27 identified as Christian, and 10 had no religion. Participants described multifaceted and contested beliefs about spirituality. Many queried the tangibility of spirituality, but all valued respectful staff who affirmed personhood, that is, each individual’s worth, especially when care exceeded expectations. They also resonated with positive organizational and environmental tones that improved holistic well-being. Participants stressed the importance of the hospital’s welcoming context and skilled care, which comforted and reassured.
Conclusion: Although many patients and caregivers did not resonate with the term ‘‘spiritual care,’’ all described how the hospital’s hospitality could affirm their values and strengthen coping. The phrase ‘‘spiritual care and hospitality’’ may optimally articulate and guide care in similar, pluralist inpatient palliative care contexts, recognizing that such care encompasses an interplay of generalist and specialist pastoral care staff and organizational and environmental qualities
Multiscale habitat characterization of herbaceous Atlantic Coastal Plain Flora on lakeshores in Nova Scotia
Accepted VersionAtlantic Coastal Plain Flora (ACPF) are a group of plants mostly inhabiting lakeshores along the Atlantic coast of the United States, with disjunct populations in Nova Scotia and Ontario. To better define their ecological requirements, the main objective of this study was to determine the factors (biotic and abiotic habitat components) influencing ACPF communities (distribution, species abundance, and richness) at both the landscape and local scales. On 16 lakeshores in southwestern Nova Scotia, we characterized ACPF communities and habitat within 20 cm square contiguous quadrats distributed along 20 m transects (landscape scale) and in 5 m × 5 m grids (local scale). Performing redundancy analysis (n = 16 transects), we found that at the landscape scale, shoreline slope and shrub species distribution influenced the quantity of suitable habitat available for ACPF, with mineral shorelines supporting higher ACPF richness. Using spatial generalized linear mixed models (n = 3125 quadrats in five grids), we found that elevation, vegetation elements (shrubs, sundews, graminoids), and substrate type mostly influenced ACPF presence and abundance. ACPF also showed inter-specific differences in habitat preferences. Defining ACPF ecological requirements at both the landscape and local scales is important to guide conservation and management actions in Nova Scotia and throughout their North American range
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats
Background: The combination of systemic arterial hypertension and diabetes mellitus (DM) induces greater cardiac remodeling than either condition alone. However, this association has been poorly addressed in senescent rats. Therefore, this study aimed to analyze the influence of streptozotocin-induced DM on ventricular remodeling and oxidative stress in aged spontaneously hypertensive rats (SHR).Methods: Fifty 18 month old male SHR were divided into two groups: control (SHR, n = 25) and diabetic (SHR-DM, n = 25). DM was induced by streptozotocin (40 mg/kg, i.p.). After nine weeks, the rats underwent echocardiography and myocardial functional study in left ventricular (LV) isolated papillary muscle preparations. LV samples were obtained to measure myocyte diameters, interstitial collagen fraction, and hydroxyproline concentration. Gene expression of atrial natriuretic peptide (ANP) and alpha- and beta-myosin heavy chain (MyHC) isoforms was evaluated by RT-PCR. Serum oxidative stress was assessed by measuring lipid hydroperoxide concentration and superoxide dismutase and glutathione peroxidase activities. Statistics: Student's t test or Mann-Whitney test, p < 0.05.Results: SHR-DM presented higher blood glucose (487 +/- 29 vs. 89.1 +/- 21.1 mg/dL) and lower body weight (277 +/- 26 vs. 339 +/- 38 g). Systolic blood pressure did not differ between groups. Echocardiography showed LV and left atrial dilation, LV diastolic and relative wall thickness decrease, and LV systolic and diastolic function impairment in SHR-DM. Papillary muscle study showed decreased myocardial contractility and contractile reserve in SHR-DM. Myocyte diameters and myocardial interstitial collagen fraction and hydroxyproline concentration did not differ between groups. Increased serum pro-oxidant activity and gene expression of ANP and beta/alpha-MyHC ratio were observed in DM.Conclusion: Diabetes mellitus induces cardiac dilation and functional impairment, increases oxidative stress and activates fetal gene program in aged spontaneously hypertensive rats.Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior (CAPES)Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells.
Plasma membrane tension regulates many key cellular processes. It is modulated by, and can modulate, membrane trafficking. However, the cellular pathway(s) involved in this interplay is poorly understood. Here we find that, among a number of endocytic processes operating simultaneously at the cell surface, a dynamin independent pathway, the CLIC/GEEC (CG) pathway, is rapidly and specifically upregulated upon a sudden reduction of tension. Moreover, inhibition (activation) of the CG pathway results in lower (higher) membrane tension. However, alteration in membrane tension does not directly modulate CG endocytosis. This requires vinculin, a mechano-transducer recruited to focal adhesion in adherent cells. Vinculin acts by controlling the levels of a key regulator of the CG pathway, GBF1, at the plasma membrane. Thus, the CG pathway directly regulates membrane tension and is in turn controlled via a mechano-chemical feedback inhibition, potentially leading to homeostatic regulation of membrane tension in adherent cells
Análise do mercado de serviços de regulação de frequência secundária e terciária no sistema eléctrico português
Dissertação para obtenção do grau de Mestre em Engenharia Electrotécnica Ramo EnergiaOs operadores das redes de transporte (ORT) enfrentam desafios cada vez maiores e mais imprevisÃveis. A forte penetração de energias renováveis e a liberalização do mercado de energia eléctrica dão origem a uma maior volatilidade na produção de energia eléctrica e a desencontros entre produção e consumo, passÃveis de acontecer no decorrer da operação do sistema eléctrico. Os serviços de sistema são um complemento aos mercados de energia eléctrica e caracterizam-se como sendo uma segurança necessária ao bom funcionamento do sistema pois é através destes que é feito o equilÃbrio entre geração e consumo em tempo real e assim feita a regulação de frequência da rede eléctrica.
Com o presente trabalho pretende-se fazer uma análise aprofundada do que são os serviços de sistema para regulação de frequência, nomeadamente sobre a regulação secundária e a regulação terciária bem como abordar a regulamentação que as fundamenta. Será também aprofundado o funcionamento do mercado de serviços de sistema para regulação de frequência em Portugal e oencadeamento cronológico deste com o mercado diário e com as diversas sessões intradiárias do Mercado Ibérico de Electricidade (MIBEL). Serão ainda referidos diversos serviços de sistema noutros paÃses europeus em comparação com Portugal.
Para apoio a esta análise desenvolveu-se uma ferramenta em Matlab®que permita visualizar sob a
forma de gráficos as ofertas dos agentes de mercado participantes através das suas unidades fÃsicas (grupos geradores), o custo marginal dessas mesmas centrais e ainda visualizar o preço de fecho de mercado na respectiva hora.
Os resultados obtidos apontam para uma dependência do perfil de licitação relativamente à tecnologia da central. Foram ainda analisadas as correlações entre centrais e a dependência do preço das ofertas e da banda contratada relativamente à existência de meses mais ou menos chuvosos, ou seja com maior ou menos Ãndice de produtibilidade hidroeléctrica (IPH). Denota-se ainda uma elevada participação das centrais hÃdricas neste mercado de banda secundária.Abstract: The transmission system operators (TSO) face increasing and more unpredictable challenges. The high penetration of renewable energy and the liberalization of the electricity market rises the volatility in electricity generation and bigger differences between production and consumption, in the course of the electrical system operation. Ancillary services are a complement to electricity markets and are characterized as a necessary service that allows a proper and reliable functioning of the system as it is the mechanism that allows the TSO to balance generation and consumption in real time operation and control the frequency of the system.
The present work aims to make a thorough analysis of what are the ancillary services for frequency regulation, particularly on secondary regulation and tertiary regulation and to address the laws that allow to develop the frequency regulation in Portugal. It will also be studied the operation of the ancillary services market for frequency regulation in Portugal and the chronological connection with the daily market and the various intraday market sessions of Iberian Electricity Market (MIBEL). Itwill be studied also various ancillary services in other European countries compared to Portugal.
To support this data analysis a Matlab® tool was developed allowing the user to view in the graphical form the offers of market players participating with their physical units (power plants), the marginal cost of these same power plants and the market clearing price, all for the same selected period of time.
The results show a dependence of the bidding profile relative to the power plant technology. It will be also studied the correlations between different power plants and the price variation of the market due to the variation of the hydroelectric capability factor (HCF) variation. It is also relevant the high share of hydro power plants participating in the ancillary services market for secondary frequency control
All Staphylococcus aureus bacteraemia-inducing strains can cause infective endocarditis:Results of GWAS and experimental animal studies
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