The impact of written exposure on worry : efficacy and mechanisms

The main goal of this research was to examine the effect of written exposure on GAD-related symptoms in high worriers. Thirty (30) nonclinical high worriers were randomly assigned to either a written exposure condition ( n = 15) or a control writing condition ( n = 15). Participants in the exposure condition wrote emotional descriptions of feared outcomes, whereas participants in the control condition wrote objectively about a neutral, hypothetical situation. All participants wrote for 30 minutes each day over five consecutive days. Self-report measures were used to assess worry, GAD somatic symptoms, depression, and intolerance of uncertainty at four time points during the study: pretest, posttest, and 1- and 2-week follow-ups. Given that exposure-based treatments are effective for GAD and related symptoms (e.g., Borkovec, Wilkinson, Folensbee, & Lerman, 1983; Dugas et al., 2003), we hypothesized that the exposure group would show greater decreases in symptoms (i.e., worry, GAD somatic symptoms, and depression) than would the control group. Further, considering that changes in intolerance of uncertainty generally precede changes in worry over the course of treatment for GAD (Dugas & Ladouceur, 2000), we expected that intolerance of uncertainty scores would predict subsequent symptom scores in the exposure group. Using hierarchical linear modeling (HLM), we found that all symptoms significantly decreased over time in the written exposure group (although GAD somatic symptoms also decreased in the control group). Moreover, intolerance of uncertainty scores predicted subsequent scores on all symptom measures in the experimental group, whereas worry and depression scores predicted subsequent intolerance of uncertainty scores in the control group

Towards a Culturally Inclusive Model of Care: Quality Practice and Care Through the Lens of a Practising Nurse

When a nurse cares for a patient there is a set of expectations which must be met; not only for the management of health needs, but also to address interpersonal and social needs. Every person is different. Their values and belief systems and the cultural practices they follow, impact on how they like nursing care to be appropriated. The individual nurse varies in how they manage their patient’s care. They may not necessarily perceive or accommodate differences within and amongst people for whom they are caring. Locally, Australian indigenous nurses, Aborigines, have been under-represented in the nursing workforce and recognition of Aboriginal patients’ cultural needs have been surpassed by dominant Western culture. This is despite national health policy evolving, aimed at raising awareness of traditional owners’ beliefs and values. This chapter is a reflection on a practicing nurse’s experiences in delivering scientifically-sound care amid patients’ needs and best interests

Program Profile 8: Chapman University: Bridging the Gap with Action Research

In the English Department at Chapman, all graduate students are eligible to apply for positions as GTAs after they have completed a graduate seminar in teaching composition. Those who are offered and accept GTA positions take a second graduate seminar, composition pedagogy and research practicum, simultaneously with their first semester of teaching. In order to encourage GTAs to develop identities as teacher-scholars, GTAs develop IRB-approved action research projects (Buyserie; Hawkes; Hudson et al.; Souleles) as their major work in this second seminar. These action research projects allow GTAs to research a question they have about the teaching of composition, using their own students as the sources of their data. Thus, they are learning how (their own) teacher-knowledge can be a source of expertise in the fields of pedagogy and composition, and the action research project becomes a central component of and bridge between their teaching (their identities as teachers, since they initiate, shape, and undertake the research as the instructor of their first-year composition class) and their scholarship (their identities as students, since they are learning how to undertake an action research project and are completing it as a graduate student assignment). Many GTAs have gone on to use their action research projects as the basis for MA theses and conference papers.https://digitalcommons.chapman.edu/english_books/1039/thumbnail.jp

Exoplanet Classification and Yield Estimates for Direct Imaging Missions

Future NASA concept missions that are currently under study, like Habitable Exoplanet Imaging Mission (HabEx) & Large Ultra-Violet Optical Infra Red (LUVOIR) Surveyor, would discover a large diversity of exoplanets. We propose here a classification scheme that distinguishes exoplanets into different categories based on their size and incident stellar flux, for the purpose of providing the expected number of exoplanets observed (yield) with direct imaging missions. The boundaries of this classification can be computed using the known chemical behavior of gases and condensates at different pressures and temperatures in a planetary atmosphere. In this study, we initially focus on condensation curves for sphalerite ZnS, H2O, CO2 and CH4. The order in which these species condense in a planetary atmosphere define the boundaries between different classes of planets. Broadly, the planets are divided into rocky (0.5 - 1.0RE), super-Earths (1.0- 1.75RE), sub-Neptunes (1.75-3.5RE), sub-Jovians (3.5 - 6.0RE) and Jovians (6-14.3RE) based on their planet sizes, and 'hot', 'warm' and 'cold' based on the incident stellar flux. We then calculate planet occurrence rates within these boundaries for different kinds of exoplanets, \eta_{planet}, using the community co-ordinated results of NASA's Exoplanet Program Analysis Group's Science Analysis Group-13 (SAG-13). These occurrence rate estimates are in turn used to estimate the expected exoplanet yields for direct imaging missions of different telescope diameter.Comment: Accepted to Astrophysical Journal. 30 pages, 4 tables. Online tool for classification boundaries can be found at: http://www3.geosc.psu.edu/~ruk15/planets

Exoplanet Diversity in the Era of Space-based Direct Imaging Missions

This whitepaper discusses the diversity of exoplanets that could be detected by future observations, so that comparative exoplanetology can be performed in the upcoming era of large space-based flagship missions. The primary focus will be on characterizing Earth-like worlds around Sun-like stars. However, we will also be able to characterize companion planets in the system simultaneously. This will not only provide a contextual picture with regards to our Solar system, but also presents a unique opportunity to observe size dependent planetary atmospheres at different orbital distances. We propose a preliminary scheme based on chemical behavior of gases and condensates in a planet's atmosphere that classifies them with respect to planetary radius and incident stellar flux.Comment: A white paper submitted to the National Academy of Sciences Exoplanet Science Strateg

Caspian: Os Results from a Randomised Phase 3 Study of First-Line Durvalumab ± Tremelimumab + Chemotherapy in ES-SCLC

Immune checkpoint blockade targeting the PD-1/PD-L1 pathway in combination with platinum-based chemotherapy (CT) has demonstrated improved clinical outcomes in patients (pts) with extensive-stage small-cell lung cancer (ES-SCLC). Durvalumab ± Tremelimumab in combination with etoposide and platinum-based CT (EP) as first-line treatment for pts with ES-SCLC. Results will be presented at WCLC 2019 including OS, key secondary endpoints, safety and tolerability

The Need for Laboratory Measurements and Ab Initio Studies to Aid Understanding of Exoplanetary Atmospheres

We are now on a clear trajectory for improvements in exoplanet observations that will revolutionize our ability to characterize their atmospheric structure, composition, and circulation, from gas giants to rocky planets. However, exoplanet atmospheric models capable of interpreting the upcoming observations are often limited by insufficiencies in the laboratory and theoretical data that serve as critical inputs to atmospheric physical and chemical tools. Here we provide an up-to-date and condensed description of areas where laboratory and/or ab initio investigations could fill critical gaps in our ability to model exoplanet atmospheric opacities, clouds, and chemistry, building off a larger 2016 white paper, and endorsed by the NAS Exoplanet Science Strategy report. Now is the ideal time for progress in these areas, but this progress requires better access to, understanding of, and training in the production of spectroscopic data as well as a better insight into chemical reaction kinetics both thermal and radiation-induced at a broad range of temperatures. Given that most published efforts have emphasized relatively Earth-like conditions, we can expect significant and enlightening discoveries as emphasis moves to the exotic atmospheres of exoplanets.Comment: Submitted as an Astro2020 Science White Pape

Planetary Candidates Observed by Kepler, III: Analysis of the First 16 Months of Data

New transiting planet candidates are identified in sixteen months (May 2009 - September 2010) of data from the Kepler spacecraft. Nearly five thousand periodic transit-like signals are vetted against astrophysical and instrumental false positives yielding 1,091 viable new planet candidates, bringing the total count up to over 2,300. Improved vetting metrics are employed, contributing to higher catalog reliability. Most notable is the noise-weighted robust averaging of multi-quarter photo-center offsets derived from difference image analysis which identifies likely background eclipsing binaries. Twenty-two months of photometry are used for the purpose of characterizing each of the new candidates. Ephemerides (transit epoch, T_0, and orbital period, P) are tabulated as well as the products of light curve modeling: reduced radius (Rp/R*), reduced semi-major axis (d/R*), and impact parameter (b). The largest fractional increases are seen for the smallest planet candidates (197% for candidates smaller than 2Re compared to 52% for candidates larger than 2Re) and those at longer orbital periods (123% for candidates outside of 50-day orbits versus 85% for candidates inside of 50-day orbits). The gains are larger than expected from increasing the observing window from thirteen months (Quarter 1-- Quarter 5) to sixteen months (Quarter 1 -- Quarter 6). This demonstrates the benefit of continued development of pipeline analysis software. The fraction of all host stars with multiple candidates has grown from 17% to 20%, and the paucity of short-period giant planets in multiple systems is still evident. The progression toward smaller planets at longer orbital periods with each new catalog release suggests that Earth-size planets in the Habitable Zone are forthcoming if, indeed, such planets are abundant.Comment: Submitted to ApJS. Machine-readable tables are available at http://kepler.nasa.gov, http://archive.stsci.edu/kepler/results.html, and the NASA Exoplanet Archiv

NCCN Guidelines Insights: Survivorship, Version 2.2020.

The NCCN Guidelines for Survivorship provide screening, evaluation, and treatment recommendations for consequences of adult-onset cancer and its treatment, with the goal of helping healthcare professionals who work with survivors, including those in primary care. The guidelines also provide recommendations to help clinicians promote physical activity, weight management, and proper immunizations in survivors and facilitate care coordination to ensure that all of the survivors needs are addressed. These NCCN Guidelines Insights summarize additions and changes made to the guidelines in 2020 regarding cardiovascular disease risk assessment and screening for subsequent primary malignancies