1,568 research outputs found

    Methodology for Assessing the Logistics Potential of the Foreign Economic Activity of a Pharmaceutical Company

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    The aim of the article is to determine the essence of the logistics potential of a foreign trade activity of a pharmaceutical enterprise and justify the methods for determining it.The materials used in the study include statistical data of the investigated pharmaceutical enterprises, namely JSC FF “Darnitsa”, PJSC NPC “Borschagovsky Chemical and Pharmaceutical Plant”, PJSC “Pharmak”, LLC “FC Zdorovia” and JSC “Lekhim-Kharkiv”. The study used methods of analysis and synthesis, generalization, content analysis, questionnaires and methods for assessing potential. The questionnaire was used to select indicators that should be part of the logistics potential of a foreign trade activity of a pharmaceutical enterprise.The experts were 100 leading specialists of pharmaceutical companies. They are all involved in foreign economic activity. Experts are gender–divided into women (73 %), men (27 %); by age: up to 25 years – 8 %, 25–35 years – 14 %, 35–45 years – 27 %, 45–55 years – 36 %, over 55 years – 15 %; by experience: up to 5 years – 11 %, 5–10 years – 15 %, 10–20 years – 32 %, 20–30 years – 36 %, over 30 years – 6 %. The experts\u27 conclusions are valid, the coefficient of concordance is 0.86, and the Pearson test exceeds the table value.The essence of the definition of "potential of logistics of pharmaceutical enterprise\u27s foreign trade activity" is investigated. The types of logistics potential of foreign economic activity and indicators that are appropriate to use for determining the level of development of the logistic potential in foreign economic activity are offered.The potential of logistics of foreign trade activities of pharmaceutical enterprises consists of the potentials of logistics in the field of export and import. The system of indicators for measuring the logistics potential of a foreign trade activity of a pharmaceutical enterprise contains indicators selected through content analysis and questionnaires.The method of estimation of logistics potential in foreign economic activity of pharmaceutical enterprise is offered

    Perancangan Interior Surabaya Science Centre

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    During this rapid development era with its huge development. The education and entertainment world also experience those wide range changes. The recent entertaining site provides less focus on the educational facility. Which is then leads to the situation that it is more and more difficult to find educational supportive entertaining site. As one of the major cities in Indonesia, Surabaya lack of attention to the needs of society in the field of education entertainment. “Surabaya Science Centre” Interior design is an education entertainment facility which somehow can help the people to develop better in the field of education. The main facilities such as lobby, ticket area, an areas of biologys, earth and space areas, an area of physics, chemistry area, cinema area, cafe, office, and souvenir shop area provided. The concept of “Imaginative Life” is the description of the life of the imagination game with the aim of being informative, educative, as well as entertaining. Interior design applied in Surabaya Science Centre is created based on a fun atmosphere, colorful and thematic so that visitors can change their mindset from boring science being fun and amazing

    Sensitivity-bandwidth limit in a multi-mode opto-electro-mechanical transducer

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    An opto--electro--mechanical system formed by a nanomembrane capacitively coupled to an LC resonator and to an optical interferometer has been recently employed for the high--sensitive optical readout of radio frequency (RF) signals [T. Bagci, \emph{et~al.}, Nature {\bf 507}, 81 (2013)]. Here we propose and experimentally demonstrate how the bandwidth of such kind of transducer can be increased by controlling the interference between two--electromechanical interaction pathways of a two--mode mechanical system. With a proof--of--principle device \new{operating at room temperature, we achieve a sensitivity of 300 nV/Hz^(1/2) over a bandwidth of 15 kHz in the presence of radiofrequency noise, and an optimal shot-noise limited sensitivity of 10 nV/Hz^(1/2) over a bandwidth of 5 kHz. We discuss strategies for improving the performance of the device, showing that, for the same given sensitivity, a mechanical multi--mode transducer can achieve a bandwidth} significantly larger than that of a single-mode one

    On the determination of constitutive parametersin a hyperelastic model for a soft tissue

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    The aim of this paper is to study a model of hyperelastic materials and itsapplications into soft tissue mechanics. In particular, we first determine an unbounded domain of the constitutive parameters of the model making our smoothstrain energy function to be polyconvex and hence satisfying the Legendre–Hadamard condition. Thus, physically reasonable material behaviour are described by our model with these parameters and a plently of tissues can betreated. Furthermore, we localize bounded subsets of constitutive parameters in fixed physical and very general bounds and then introduce a family of descrete stress–strain curves. Whence, various classes of tissues are characterized. Ourgeneral approach is based on a detailed analytical study of the first Piola–Kirchhoff stress tensor through its dependence on the invariants and on the constitutive parameters. The uniqueness of parameters for one tissue is discussed by introducing the notion of manifold of constitutive parameters, whichis locally represented by possibly different physical quantities. The advantage of our study is that we show a possible way to improve of the usual approachesshown in the literature which are mainly based on the minimization of a costfunction as the difference between experimental and model results

    Characterization of a defective PbWO4 crystal cut along the a-c crystallographic plane: structural assessment and a novel photoelastic stress analysis

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    Among scintillators, the PWO is one of the most widely used, for instance in CMS calorimeter at CERN and PANDA project. Crystallographic structure and chemical composition as well as residual stress condition, are indicators of homogeneity and good quality of the crystal. In this paper, structural characterization of a defective PbWO4 (PWO) crystal has been performed by X-ray Diffraction (XRD), Energy Dispersive Spectroscopy (EDS) and Photoelasticity in the unusual a-c crystallographic plane. XRD and EDS analysis have been used to investigate crystallographic orientation and chemical composition, while stress distribution, which indicates macroscopic inhomogeneities and defects, has been obtained by photoelastic approaches, in Conoscopic and Sphenoscopic configuration. Since the sample is cut along the a-c crystallographic plane, a new method is proposed for the interpretation of the fringe pattern. The structural analysis has detected odds from the nominal lattice dimension, which can be attributed to the strong presence of Pb and W. A strong inhomogeneity over the crystal sample has been revealed by the photoelastic inspection. The results give reliability to the proposed procedure which is exploitable in crystals with other structures.Comment: 18 pages, 10 figures, revised versio

    Inflation in Brusov–Filatova–Orekhova Theory and in its Perpetuity Limit – Modigliani – Miller Theory

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    In this paper the influence of inflation on capital cost and capitalization of the company within modern theory of capital cost and capital structure – Brusov–Filatova–Orekhova theory (BFO theory) (Brusov et al. 2011, 2013; Filatova et al., 2008) and within its perpetuity limit – Modigliani – Miller theory is investigated. By direct incorporation of inflation into both theories, it is shown for the first time that inflation not only increases the equity cost and the weighted average cost of capital, but as well it changes their dependence on leverage. In particular, it increases growing rate of equity cost with leverage. Capitalization of the company is decreased under accounting of inflation

    Jacobian-Based Iterative Method for Magnetic Localization in Robotic Capsule Endoscopy

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    The purpose of this study is to validate a Jacobian-based iterative method for real-time localization of magnetically controlled endoscopic capsules. The proposed approach applies finite-element solutions to the magnetic field problem and least-squares interpolations to obtain closed-form and fast estimates of the magnetic field. By defining a closed-form expression for the Jacobian of the magnetic field relative to changes in the capsule pose, we are able to obtain an iterative localization at a faster computational time when compared with prior works, without suffering from the inaccuracies stemming from dipole assumptions. This new algorithm can be used in conjunction with an absolute localization technique that provides initialization values at a slower refresh rate. The proposed approach was assessed via simulation and experimental trials, adopting a wireless capsule equipped with a permanent magnet, six magnetic field sensors, and an inertial measurement unit. The overall refresh rate, including sensor data acquisition and wireless communication was 7 ms, thus enabling closed-loop control strategies for magnetic manipulation running faster than 100 Hz. The average localization error, expressed in cylindrical coordinates was below 7 mm in both the radial and axial components and 5° in the azimuthal component. The average error for the capsule orientation angles, obtained by fusing gyroscope and inclinometer measurements, was below 5°
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