High-resolution nested model for the Lebanese coastal area, Eastern Mediterranean: implementation and climatological runs

International audienceAs a part of the project Mediterranean Network to Assess and Upgrade Monitoring and Forecasting Activity in the Region (MAMA) we implemented a high resolution nested hydrodynamic model (1/40° horizontal grid, 16 sigma levels) for the coastal, shelf and open sea areas off the Lebanese coast, East Levantine Basin of the Eastern Mediterranean Sea. The Lebanese Shelf Model (LSM) is a version of the Princeton Ocean Model (POM). It is nested in a coarse resolution model the Aegean Levantine Eddy Resolving Model (1/20° horizontal grid, 25 sigma levels), ALERMO, that covers the Eastern Mediterranean. The nesting is one way so that velocity, temperature, and salinity along the open boundaries are interpolated from the relevant coarse model variables. Numerical simulations have been carried out under climatological surface and lateral forcing. Due to the relatively small domain, the results closely follow the simulation of the intermediate model with more details especially over the narrow shelf region. Simulations reproduce main circulation features and coastal circulation characteristics over the eastern Levantine shelf. This paper describes the modeling system setup, compares the simulations with the corresponding results of the coarse model ALERMO, and with the observed climatological circulation characteristics in the Levantine Basin off the Lebanese coast

Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta.

1 in 5 women report cannabis use during pregnancy, with nausea cited as their primary motivation. Studies show that (-)-△9-tetrahydrocannabinol (Δ9-THC), the major psychoactive ingredient in cannabis, causes fetal growth restriction, though the mechanisms are not well understood. Given the critical role of the placenta to transfer oxygen and nutrients from mother, to the fetus, any compromise in the development of fetal-placental circulation significantly affects maternal-fetal exchange and thereby, fetal growth. The goal of this study was to examine, in rats, the impact of maternal Δ9-THC exposure on fetal development, neonatal outcomes, and placental development. Dams received a daily intraperitoneal injection (i.p.) of vehicle control or Δ9-THC (3 mg/kg) from embryonic (E)6.5 through 22. Dams were allowed to deliver normally to measure pregnancy and neonatal outcomes, with a subset sacrificed at E19.5 for placenta assessment via immunohistochemistry and qPCR. Gestational Δ9-THC exposure resulted in pups born with symmetrical fetal growth restriction, with catch up growth by post-natal day (PND)21. During pregnancy there were no changes to maternal food intake, maternal weight gain, litter size, or gestational length. E19.5 placentas from Δ9-THC-exposed pregnancies exhibited a phenotype characterized by increased labyrinth area, reduced Epcam expression (marker of labyrinth trophoblast progenitors), altered maternal blood space, decreased fetal capillary area and an increased recruitment of pericytes with greater collagen deposition, when compared to vehicle controls. Further, at E19.5 labyrinth trophoblast had reduced glucose transporter 1 (GLUT1) and glucocorticoid receptor (GR) expression in response to Δ9-THC exposure. In conclusion, maternal exposure to Δ9-THC effectively compromised fetal growth, which may be a result of the adversely affected labyrinth zone development. These findings implicate GLUT1 as a Δ9-THC target and provide a potential mechanism for the fetal growth restriction observed in women who use cannabis during pregnancy

Applied Plasma Research

Contains reports on three research projects.National Science Foundation (Grant GK-10472)Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E

Synthetic models of distribution networks based on open data and georeferenced information

Many planning and operation studies that aim at fully assessing and optimizing the performance of the distribution grids, in response to the current trends, cannot ignore grid limitations. Modelling the distribution system, by including the electrical characteristics of the network (e.g., topology) and end user behaviors, has become complex, but essential, for all conventional and emerging actors/players of power systems (i.e., system and market operators, regulators, new market parties as service providers, aggregators, researchers, etc.). This paper deals with a methodology that, starting from publicly available open data on the energy consumption of a region or wider area, is capable to obtain reasonable load and generation profiles for the network supplied by each primary substation in the region/area. Furthermore, by combining these profiles with territorial and socio-economic information, the proposed methodology is able to model the network in terms of lines, conductors, loads and generators. The results of this procedure are the synthetic networks of the real distribution networks, that do not correspond exactly to the actual networks, but can characterize them in a realistic way. Such models can be used for all the kind of optimization studies that need to check the grid limitations. Results derived from Italian test cases are presented and discussed

Protein Ontology: A controlled structured network of protein entities

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments

The dust emission SED of X-ray emitting regions in Stephan's Quintet

We analysed the Spitzer maps of Stephan's Quintet in order to investigate the nature of the dust emission associated with the X-ray emitting regions of the large scale intergalactic shock and of the group halo. This emission can in principle be powered by dust-gas particle collisions, thus providing efficient cooling of the hot gas. However the results of our analysis suggest that the dust emission from those regions is mostly powered by photons. Nonetheless dust collisional heating could be important in determining the cooling of the IGM gas and the large scale star formation morphology observed in SQ.Comment: Conference proceedings IAU Symposium 284 "The Spectral energy distribution of galaxies", 5-9 September 2011, Preston, U

Relating the Quark and Gluon Condensates Through the QCD Vacuum Energy

Using the Cornwall-Jackiw-Tomboulis effective potential for composite operators we compute the QCD vacuum energy as a function of the dynamical quark and gluon propagators, which are related to their respective condensates as predicted by the operator product expansion. The identification of this result to the vacuum energy obtained from the trace of the energy-momentum tensor allow us to study the gluon self-energy, verifying that it is fairly represented in the ultraviolet by the asymptotic behavior predicted by the operator product expansion, and in the infrared it is frozen at its asymptotic value at one scale of the order of the dynamical gluon mass. We also discuss the implications of this identity for heavy and light quarks. For heavy quarks we recover, through the vacuum energy calculation, the relation m_{f} \sim - {1/12} \gc obtained many years ago with QCD sum rules.Comment: 21 pages, LaTeX, final version to appear in Physical Review

The star formation efficiency in Stephan's Quintet intragroup regions

We investigated the star formation efficiency for all the dust emitting sources in Stephan's Quintet (SQ). We inferred star formation rates using Spitzer MIR/FIR and GALEX FUV data and combined them with gas column density measurements by various authors, in order to position each source in a Kennicutt-Schmidt diagram. Our results show that the bright IGM star formation regions in SQ present star formation efficiencies consistent with those observed within local galaxies. On the other hand, star formation in the intergalactic shock region seems to be rather inhibited.Comment: Conference proceedings "Galaxy Mergers in an evolving Universe", 23-28 October 2011, Hualien, Taiwa

Diffractive production of dijets by double Pomeron exchange processes

A phenomenological description of diffractive dijet hadroproduction via double Pomeron exchange is presented. This description is based on a modified version of the Ingelman-Schlein model which includes the evolution of the Pomeron structure function and corrections regarding rapidity gap suppression effects. The same quark-dominant Pomeron structure function employed in a previous report to describe diffractive dijet and W production via single Pomeron processes is shown here to yield results consistent with the available data for double Pomeron processes as well.Comment: 4 pages, REVTEX4.

A Self-Consistent Approach to Neutral-Current Processes in Supernova Cores

The problem of neutral-current processes (neutrino scattering, pair emission, pair absorption, axion emission, \etc) in a nuclear medium can be separated into an expression representing the phase space of the weakly interacting probe, and a set of dynamic structure functions of the medium. For a non-relativistic medium we reduce the description to two structure functions S_A(\o) and S_V(\o) of the energy transfer, representing the axial-vector and vector interactions. $S_V$ is well determined by the single-nucleon approximation while $S_A$ may be dominated by multiply interacting nucleons. Unless the shape of S_A(\o) changes dramatically at high densities, scattering processes always dominate over pair processes for neutrino transport or the emission of right-handed states. Because the emission of right-handed neutrinos and axions is controlled by the same medium response functions, a consistent constraint on their properties from consideration of supernova cooling should use the same structure functions for both neutrino transport and exotic cooling mechanisms.Comment: 33 pages, Te