Machine Learning Technique for Prediction of Breast Cancer

Breast cancer is one of the most prominent disease and the second foremost source of death among middle-aged women in the world. Removing of breast tumour by using a surgical treatment and chemotherapy could work excellently if it can be identified as a primary tumour or at an early stage of transmutation, however it is a costly process. The quick development of machine learning techniques continues to burn the medical tomography enthusiasm in implementing to improve the accurateness of tumour findings. To identify breast cancer in the area of machine learning lots of attempts were made, but these techniques are not too accurate. In the proposed Machine Learning Technique for Prediction of Breast Cancer (MLTPBC) is an automated system used to remove a label, pectoral muscles, noise, and identification of cancer. The experimental results of the proposed MLTPBC shows the preferable accuracy over the existing methods

Youth and marriage : a study of changing marital choices among the university students in India

Each social group in the Indian context, whether it may be a caste or religion or tribe, has its own rules and regulations that define the practices of social relations within the group and outside the group. Marriage as a social institution establishes a social relation with the members of two families. It is largely regulated by the norms and values of the groups and society. In the same way, choice of marriage is also much influenced by caste and religious norms and values. Here, the individual preferences are constrained by the groups' norms. At this juncture, higher education has the potential role in shaping the marital choices of students. This study sets out to analyse the students' views on choices of marriage in a university campus by employing qualitative and quantitative techniques. It also attempts to explain the changing forms of marital choices and types of marriages in the university campus. For this study, extensive data was collected from 450 selected students from the University of Hyderabad (UoH) through survey research questionnaire on marital choices among the students. In order to strengthen the reliability of the data, personal opinion on marital choices was drawn from 20 selected students from different caste and religious backgrounds by using open-ended questionnaire. The data analysis shows that the students' marital choices are still influenced by cultural factors like caste, religion, class, and family

ETHNO-BOTANICAL CLAIMS COLLECTED FROM TRIBAL AND RURAL PEOPLE OF KADAPA DISTRICT, ANDHRA PRADESH

The main aim of the study is to collect the ethnobotanical claims on therapeutic actions of twenty-seven (27) plant species belonging to Fourteen (14) families of angiosperms; practicing by tribal and rural people of Kadapa district, Andhra Pradesh. The study was directed in the tribal villages and provincial regions like; Badvel, Balapalli, Chitvel, Guvvala cheruvu, Kukkaladhoddi, Lankamalai, Mamandur, Palakonda hills, Pulivendula, Rajampeta, Rayachoti and Settipalli in Kadapa District. The governed tribal populations in these regions are Yanadhi accompanied by Yerukula, Nakkala, and Sugalis. Tribal and rural people of the investigated areas have been applying all these plant materials in the form of ash, boiled, crude, curry, decoction etc. for treating 27 disease conditions like; anorexia, bilious affections, piles, burning sensation in the stomach, cold and cough, dandruff, dental diseases, diarrhoea, dyspepsia, redness of eye, facial paralysis, fever, fissures, cracks, flatulence, haemorrhage, hair loss, indigestion, intestinal ulcers, loss of libido, migraine, pains, swellings etc. The botanical name, family name, habit, habitat, part(s) used, flowering and fruiting time, the name of the diseases against which the plants are used and mode of administration with dosage for most of the claims is discussed in detail. The provided information could be used to find new medications of natural origin by the systematic research on pharmacological and clinical trials

Morphological and molecular characterization of a new microsporidian (Protozoa: Microsporidia) isolated from Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae)

A microsporidium was isolated from larvae of Spodoptera litura (Fabricius) collected from Tamil Nadu, India. This microsporidian species is monomorphic, disporous and develops in direct contact with the cytoplasm of the host cell. The nuclear configuration of merogonic and sporogonic stages was diplokaryotic. The merogonic proliferative stage was unusual that normal development with 1, 2 and 4 binucleated forms were common, while large multinucleate meronts containing 8 and 12 small compact horseshoe-like diplokaryotic nuclei were also observed. The fresh spores were typically ovocylindrical in shape, with a mean size of 3.91× 1.91 μm and the polar filament length was ~90 μm. Infection was systemic with mature spores produced in the midgut, nervous tissue, muscles, labial glands, gonads, tracheae, epidermis, Malpighian tubules and, most extensively, fat body tissues. The new isolate was highly pathogenic to S. litura larvae. Host specificity tests performed on 37 non-target hosts of 5 different insect orders revealed that the new isolate is pathogenic only to lepidopteran insects. We sequenced the 16S small subunit rRNA (SSU rRNA) gene of the isolate and compared it with 72 non-redundant microsporidian sequences from the GenBank. Based on the light microscopic studies and phylogenetic analyses, the new isolate is assigned to the genus Nosema. Significant differences in the SSU rRNA sequence were identified when compared with the type species Nosema bombycis and other closely related species viz., Nosema spodopterae. Structural differences were also observed in the 16S SSU rRNA between the new isolate and the two above-mentioned microsporidian pathogens. We conclude that the microsporidian isolate reported here is distinctly different from the other known species and is likely to be a new species

Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone

A macrocyclic hydrazone Schiff base was synthesized by reacting 1,4-dicarbonyl phenyl dihydrazide with 2,6-diformyl-4-methyl phenol and a series of metal complexes with this new Schiff base were synthesized by reaction with Co(II), Ni(II) and Cu(II) metal salts. The Schiff base and its complexes have been characterized by elemental analyses, IR, 1H NMR, UV-vis, FAB mass, ESR spectra, fluorescence, thermal, magnetic and molar conductance data. The analytical data reveal that the Co(II), Ni(II) and Cu(II) complexes possess 2:1 metal-ligand ratios. All the complexes are non-electrolytes in DMF and DMSO due to their low molar conductance values. Infrared spectral data suggest that the hydrazone Schiff base behaves as a hexadentate ligand with NON NON donor sequence towards the metal ions. The ESR spectral data shows that the metal-ligand bond has considerable covalent character. The electrochemical behavior of the copper(II) complex was investigated by cyclic voltammetry. The Schiff base and its complexes have also been screened for their antibacterial (Escherichia coli, Staphylococcus aureus, Shigella dysentery, Micrococcus, Bacillus subtilis, Bacillus cereus and Pseudomonas aeruginosa) and antifungal activities (Aspergillus niger, Penicillium and Candida albicans) by MIC method. The brine shrimp bioassay was also carried out to study their in-vitro cytotoxic properties. © 2009 Elsevier Masson SAS. All rights reserved

An Empirical Critique of On-Demand Routing Protocols against Rushing Attack in MANET

Over the last decade, researchers had  proposed numerous  mobile ad hoc routing protocols for which are operate in an on-demand way, as standard on-demand routing protocols such as AODV, DSR and TORA, etc., have been shown to often have faster reaction time and  lower overhead than proactive protocols. However, the openness of the routing environment and the absence of centralized system and infrastructure make them exposed to security attacks in large extent.  In particular, one such kind of attacks is rushing attack, which is mostly hard to detect due to their inherited properties, that alters the network statistics radically. In this paper, we modeled a rushing attack which is a powerful attack that exploits the weaknesses of the secure routing protocols. Moreover, to know the weakness and strength of these protocols, it is necessary to test their performance in hostile environments. Subsequently, the performance is measured with the various metrics, some ot them are average throughput, packet delivery ratio, average end-to-end delay and etc., to compare and evaluate their performance

Vibrational Analysis in Condition Monitoring and faults Diagnosis of Rotating Shaft - Over View

Rotating shaft is a vital element in power stations like Gas power stations, steam power station and Tidal power stations. These shaft failure or break down lead to the consequences, ranges from annoyance to the financial disaster or human damage. Hence predictive maintenance which includes early detection, identification and correction of machinery problems is paramount to anyone involved in the maintenance of industrial machinery to insure continued, safe and productive operation. Condition monitoring of machines is become necessary to run the machines efficiently. Vibrations are caused due to unbalance in the rotating components, dry friction between the two mating surfaces, misalignments, imperfect of coupling or bearings, and cracks in the shafts or blades. In predictive maintenance, vibration monitoring and analysis is essential. Health of any rotating shaft can be identified by its signature includes number of peaks. The peaks in the spectrum or signature give the information regarding the type of fault. In this paper gives a overview on vibrations analysis and faults diagnosis in various rotating machine parts and also this paper attempts to epitomize the recent research and developments in rotating element vibration analysis techniques

The hemostatic activity of Manilkara zapota (L.) P. Royen latex associated with fibrinogenolytic activity

Manilkara zapota (L.) P. Royen (Sapotaceae), is widely used in traditional medicine for various ailments like, diarrhea, pulmonary diseases, piles, ulcers and to treat wounds. The present study evaluates the role of M. zapota latex in hemostasis. The processed latex named as M. zapota natant latex (MzNL), has proteins at the concentration of 8 mg/ml and showed protein bands in Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). The proteolytic activity of MzNL was evaluated using casein in comparison with trypsin. The phenylmethylsulfonyl fluoride (PMSF) inhibited the protease activity indicating the possible presence of serine protease. The effect of temperature, pH and metal ions on proteolytic activity was evaluated. MzNL exhibited fibrinogenolytic activity by hydrolysing A? and B? subunits of fibrinogen. However, ? subunit remained resistant for hydrolysis. MzNL hydrolyzed all the subunits of collagen type I and IV at the concentration of 8 µg and 25 µg in 20 µl each respectively. MzNL showed procoagulant activity and is devoid of hemolytic activity. Fibrinogenolytic activity and procoagulant nature of MzNL suggests its possible role in blood coagulation that in turn restores hemostasis

A prospective comparative study of functional outcome of distal extra articular tibia fracture fixed with intramedullary nail versus locking compression plate

Background: Distal tibia fractures are one of the most common long bone fractures and their management presents with a series of problems due to the soft tissue surroundings and even more at risk due to their proximity to ankle joint. In our paper we showed functional outcome of distal extra articular tibia fracture while comparing its management between intramedullary nailing and locking compression plate.Methods: There were 40 patients from November 2019 to November 2020 with distal extra articular tibia fracture. Patients were divided into 2 groups, first group included 20 patients managed with intramedullary nail and the second group included 20 patients managed with locking compression plate. Patients were followed preoperatively, intraoperatively and postoperatively for functional outcome and assessed clinically using AOFAS score and radiologically using X-ray.Results: Out of the 40 cases treated in this manner, all cases were available for the follow up for a period of 1 year. Overall results by 1 year follow up showed excellent in 7 cases (35%) good in 13 cases (65%) in nailing group and in plating group showed excellent in 4 cases (20%), good in 12 cases (60%), fair in 3 cases (15%) and poor in 1 case (5%).Conclusions: All fractures united well. Complications were encountered in 4 patients, 2 patients had superficial wound infections,1 patient had deep infection and another had persistent ankle pain in plating group and 2 patients had superficial wound infection in nailing group. No cases showed malunion or nonunion in both plating as well as nailing group