21,209 research outputs found
Memristor-based Random Access Memory: The delayed switching effect could revolutionize memory design
Memristorâs on/off resistance can naturally store binary bits for non-volatile memories. In this work, we found that memristorâs another peculiar feature that the switching takes place with a time delay (we name it âthe delayed switchingâ) can be used to selectively address any desired memory cell in a crossbar array. The analysis shows this is a must-be in a memristor with a piecewise-linear ?-q curve. A âcircuit modelâ-based experiment has verified the delayed switching feature. It is demonstrated that memristors can be packed at least twice as densely as semiconductors, achieving a significant breakthrough in storage density
Palmatine inhibits TRIF-dependent NF-kB pathway against inflammation induced by LPS in goat endometrial epithelial cells
Manajemen Pendidikan Islam sebagai Disiplin Ilmu
Suatu lembaga pendidikan pastilah memerlukan yang namanya manajemen. Dikatakan demikian karena dengan manajemen mencakup pengaturan secara luas, baik dari segi sumber daya manusia sekolah maupun hal hal yang terkait lembaga itu tersendiri. Contoh saja dalam hal siswa, perlu yang namanya manajemen kesiswaan, karena dengan manajemen kesiswaan, Siswa diatur atau didesain bagaimana siswa itu menguasai mata pelajaran dengan baik sehingga menghasilkan lulusan yang baik pula. Oleh karenanya manajemen pendidikan merupakan bagian dari khazanah keilmuan. Dikatakan demikian karena dari kata ilmu itu sendiri apabila kita kaji dan telaah, maka sangatlah luas isi cakupannya, bisa dalam hal pendidikan atau hal - hal lain.Dari uraian tersebut bisa dipahami bahwasanya dalam bidang pendidikan terutama pendidikan Islam perlu yang namanya suatu ilmu yang dinamakan manajemen. Dikatakan demikian karena dengan manajemen, pendidikan Islam itu di kelola dengan baik sehingga menghasilkan apa yang diharapkan. Oleh karena itu dari sini perlu dikaji secara mendalam agar lebih memahamkan yang dikehendaki manajemen pendidikan Islam sebagai disiplin ilmu
Cumulative Neurological Factors Associated with Long-term Outcomes in Adult Survivors of Childhood Brain Tumors
Prior research has demonstrated the reliability and validity of the Neurological Predictor Scale (NPS) in relation to childhood brain tumor survivor outcomes; however, its use has not been examined in adult long-term survivors. The current study examines the concurrent validity of the NPS with long-term intellectual and adaptive outcomes in adult survivors of childhood brain tumors relative to individual variables alone. A total of 68 adult survivors of childhood brain tumors (M = 24 years old, SD = 4) almost 16 years post diagnosis (SD = 6) completed intellectual evaluations using the Wechsler Abbreviated Scale of Intelligence (WASI). Survivors\u27 adaptive functioning skills were assessed via informant structured clinical interviews (SIB-R). NPS scores were computed from data acquired from medical records. The NPS was significantly associated with intellectual (R2 = 0.208, p \u3c .05) and adaptive outcomes (R2 = 0.30, p \u3c .05) over and above individual risk factors. Approximately 18% of long-term survivors were identified as impaired in intellectual outcomes, and 29% were identified as impaired in adaptive functioning in everyday life skills. The NPS quantifies the cumulative effects of treatment and neurological sequelae experienced by both short- and long-term survivors of childhood brain tumors. It is a useful and easy measure to employ in clinical research that focuses on quantifying the neurological risk factors associated with long-term intellectual and adaptive functioning outcomes in adult survivors of childhood brain tumors
Hurst parameter analysis of radio pulsar timing noise
We present an analysis of timing residual (noise) of 54 pulsars obtained from
25-m radio telescope at Urumqi Observatory with a time span of 5~8 years,
dealing with statistics of the Hurst parameter. The majority of these pulsars
were selected to have timing noise that look like white noise rather than
smooth curves. The results are compared with artificial series of different
constant pairwise covariances. Despite the noise like appearance, many timing
residual series showed Hurst parameters significantly deviated from that of
independent series. We concluded that Hurst parameter may be capable of
detecting dependence in timing residual and of distinguishing chaotic behavior
from random processes.Comment: 7 pages, 3 figures, 2 tables, Submitted to MNRA
Exploring multipartite quantum correlations with the square of quantum discord
We explore the quantum correlation distribution in multipartite quantum
states based on the square of quantum discord (SQD). For tripartite quantum
systems, we derive the necessary and sufficient condition for the SQD to
satisfy the monogamy relation. Particularly, we prove that the SQD is
monogamous for three-qubit pure states, based on which a genuine tripartite
quantum correlation measure is introduced. In addition, we also address the
quantum correlation distributions in four-qubit pure states. As an example, we
investigate multipartite quantum correlations in the dynamical evolution of
multipartite cavity-reservoir systems.Comment: 8 pages, 5 figure
Neural underpinnings of working memory in adult survivors of childhood brain tumors
Objective: Adult survivors of childhood brain tumors are at risk for cognitive performance deficits that require the core cognitive skill of working memory. Our goal was to examine the neural mechanisms underlying working memory performance in survivors. Method: We studied the working memory of adult survivors of pediatric posterior fossa brain tumors using a letter n-back paradigm with varying cognitive workload (0-, 1-, 2-, and 3-back) and functional magnetic resonance imaging as well as neuropsychological measures. Results: Survivors of childhood brain tumors evidenced lower working memory performance than demographically-matched healthy controls. Whole-brain analyses revealed significantly greater blood-oxygen level dependent (BOLD) activation in the left superior / middle frontal gyri and left parietal lobe during working memory (2-back versus 0-back contrast) in survivors. Left frontal BOLD response negatively correlated with 2- and 3-back working memory performance, Auditory Consonant Trigrams (ACT), and Digit Span Backwards. In contrast, parietal lobe BOLD response negatively correlated with 0-back (vigilance task) and ACT. Conclusions: The results revealed that adult survivors of childhood posterior fossa brain tumors recruited additional cognitive control resources in the prefrontal lobe during increased working memory demands. This increased prefrontal activation is associated with lower working memory performance and is consistent with the allocation of latent resources theory
Exogenous gonadotropins have little impact on follicular but considerable effect on serum cytokine concentrations â a comparison between Natural Cycle and stimulated IVF using a multiplexed assay platform
Introduction: Throughout follicular growth and subsequent corpus luteum formation the leukocyte number increases and follicular vascularisation changes. These processes are enhanced under exogenous stimulation with gonadotropins. Cytokines released by leukocytes contribute to further recruitment and vascularisation of the follicle, and they play an important role in regulating ovarian steroidogenesis by influencing theca and granulosaâlutein cell function. Changes in cytokine and vascular endothelial growth factor (VEGF) concentrations in the ovary as a consequence of gonadotropin stimulation may negatively influence oocyte quality. In this project we have compared the intrafollicular production of inflammatory cytokines and growth factors between natural IVF cycles (NC) and classical, gonadotropin-stimulated IVF cycles (gsIVF).
Material and Methods: Serum on the day of oocyte retrieval and follicular fluid (FF) were collected in 37 NC and 39 gsIVF cycles. Thirteen women within this population underwent one NC and one gsIVF cycle each. A total of 14 cytokines from Bio-Plex panels I and II were determined in matched serum and FF samples using Luminex xMAP technology on the Bio-Plex(R) platform, using the serum protocol.
Results: Tumour necrosis factor-alpha, RANTES, eotaxin and interferon-gamma-induced protein-10 levels were lower in FF than in serum, and thus not further investigated. Interleukin (IL)-6, -8, -10, -15, -18, monocyte chemotactic protein-1 (MCP-1), VEGF and leukaemia inhibitory factor (LIF) showed higher median concentrations in FF than in serum, indicating possible ovarian production. Moreover, most of these showed higher evels in the gsIVF than in the NC groups in the serum, but not in the follicular fluid. IL-8 was reduced in gsIVF cycles.
Conclusion: The fact that serum but not FF levels of the studied cytokines were higher in the stimulated than in the natural cycles can be attributed to the increased number of active follicles present after controlled ovarian stimulation
Improvement of the old reductions of irregular satellites using the first publications of the data
Program available at: http://www.imcce.fr/hosted_sites/naroo/program.htmlInternational audienceThe use of long-exposure photographic plates made the discovery of additional natural satellites possible. The first satellite to be discovered in this manner, Phoebe, was found in 1899 by W.H. Pickering. A reliable model of satellite motion must be constructed with high accurate observations and with data spreading over a period as long as possible. Some old literatures have given the positions of the natural satellites and the reference stars for determining its positions. At that time, the catalogue they used did not contain enough stars, so there were not many catalogue stars on the plates. Because of the unsatisfactory precision of the old catalogue at the epoch and the imprecise measurements on the plate, the positions of the reference stars were not very precise. At present, although we have no plates, we can reduce the positions of the natural satellites from the row data provided in these literatures with modern precise astrometric catalogues, such as PPM and UCAC2. The purpose of this work is to reduce the old observations of Phoebe (Saturn IX), in order to improve its orbit
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