5,557 research outputs found

    Grievance Procedures and the Democratization of American Life

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    [Excerpt] No institution in the nation\u27s history has struggled so long and so valiantly for the democratization of American life as the organized labor movement. Decade after decade, trade unionists have fought for human rights and dignity against almost insuperable forces of wealth, privilege, and partisan government, including the country\u27s courts, soldiery, and police. They have battled against poverty of means, mind, and spirit in the teeth of bayonets, massacre, assault, injunctions, imprisonment, dismissal from jobs, blacklisting, and legislative and judicial defeat of vital measures

    Preface

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    [Excerpt] The six short essays in this modest publication assess the impact upon industrial relations of the accelerating democratization of American life

    Preface

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    [Excerpt] The six short essays in this modest publication assess the impact upon industrial relations of the accelerating democratization of American life

    Lyman alpha radiation in external galaxies

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    The Ly alpha line of atomic hydrogen is often a luminous component of the radiation emitted by distant galaxies. Except for those galaxies which have a substantial central source of non-stellar ionizing radiation, most of the Ly alpha radiation emitted by galaxies is generated within regions of the interstellar medium which are photoionized by starlight. Conversely, much of the energy radiated by photoionized regions is carried by the Ly alpha line. Only hot, massive stars are capable of ionizing hydrogen in the interstellar medium which surrounds them, and because such stars are necessarily short-lived, Ly alpha emission traces regions of active star formation. Researchers argue that the strength of the Ly alpha emission observed from external galaxies may be used to estimate quantitatively the dust content of the emitting region, while the Ly alpha line profile is sensitive to the presence of shock waves. Interstellar dust particles and shock waves are intimately associated with the process of star formation in two senses. First, both dust particles and shock waves owe their existence to stellar activity; second, they may both serve as agents which facilitate the formation of stars, shocks by triggering gravitational instabilities in the interstellar gas that they compress, and dust by shielding star-forming molecular clouds from the ionizing and dissociative effects of external UV radiation. By using Ly alpha observations as a probe of the dust content in diffuse gas at high redshift, we might hope to learn about the earliest epochs of star formation

    Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B.

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    Sanfilippo syndrome type B (MPS IIIB) is characterized by profound mental retardation in childhood, dementia and death in late adolescence; it is caused by deficiency of α-N-acetylglucosaminidase and resulting lysosomal storage of heparan sulfate. A mouse model, generated by homologous recombination of the Naglu gene, was used to study pathological changes in the brain. We found earlier that neurons in the medial entorhinal cortex (MEC) and the dentate gyrus showed a number of secondary defects, including the presence of hyperphosphorylated tau (Ptau) detected with antibodies raised against Ptau in Alzheimer disease brain. By further use of immunohistochemistry, we now show staining in neurons of the same area for beta amyloid, extending the resemblance to Alzheimer disease. Ptau inclusions in the dentate gyrus of MPS IIIB mice were reduced in number when the mice were administered LiCl, a specific inhibitor of Gsk3β. Additional proteins found elevated in MEC include proteins involved in autophagy and the heparan sulfate proteoglycans, glypicans 1 and 5, the latter closely related to the primary defect. The level of secondary accumulations was associated with elevation of glypican, as seen by comparing brains of mice at different ages or with different mucopolysaccharide storage diseases. The MEC of an MPS IIIA mouse had the same intense immunostaining for glypican 1 and other markers as MPS IIIB, while MEC of MPS I and MPS II mice had weak staining, and MEC of an MPS VI mouse had no staining at all for the same proteins. A considerable amount of glypican was found in MEC of MPS IIIB mice outside of lysosomes. We propose that it is the extralysosomal glypican that would be harmful to neurons, because its heparan sulfate branches could potentiate the formation of Ptau and beta amyloid aggregates, which would be toxic as well as difficult to degrade

    Interstellar water chemistry: from laboratory to observations

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    Water is observed throughout the universe, from diffuse interstellar clouds to protoplanetary disks around young stars, and from comets in our own solar system and exoplanetary atmospheres to galaxies at high redshifts. This review summarizes the spectroscopy and excitation of water in interstellar space as well as the basic chemical processes that form and destroy water under interstellar conditions. Three major routes to water formation are identified: low temperature ion-molecule chemistry, high-temperature neutral-neutral chemistry and gas-ice chemistry. The rate coefficients of several important processes entering the networks are discussed in detail; several of them have been determined only in the last decade through laboratory experiments and theoretical calculations. Astronomical examples of each of the different chemical routes are presented using data from powerful new telescopes, in particular the Herschel Space Observatory. Basic chemical physics studies remain critically important to analyze astronomical data.Comment: Authors' manuscript 138 pages, 34 figures, 4 tables, published in a Thematic Issue "Astrochemistry" in Chemical Reviews (December 2013), volume 113, 9043-9085 following peer review by the American Chemical Society. The published paper is available as open access at http://pubs.acs.org/doi/abs/10.1021/cr400317

    Introduction to \u3ci\u3eIndustrial Relations at the Dawn of the New Millenium\u3c/i\u3e

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    [Excerpt] The essays assembled in the volume focus upn the state of the art of industrial relations at the dawn of the new millennium. The authors of these essays are members of the faculty of the School of Industrial and Labor Relations at Cornell University, or were formerly closely associated with the school. They have found, to their delight, that in creating the essays presented here, they released an enchantment of scholarly memory that illuminates the past and present states of the scholarly disciplines they cultivate and encourages speculation about the future of these disciplines

    Excitable media in open and closed chaotic flows

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    We investigate the response of an excitable medium to a localized perturbation in the presence of a two-dimensional smooth chaotic flow. Two distinct types of flows are numerically considered: open and closed. For both of them three distinct regimes are found, depending on the relative strengths of the stirring and the rate of the excitable reaction. In order to clarify and understand the role of the many competing mechanisms present, simplified models of the process are introduced. They are one-dimensional baker-map models for the flow and a one-dimensional approximation for the transverse profile of the filaments.Comment: 14 pages, 16 figure

    ISO observations of far-infrared rotational emission lines of water vapor toward the supergiant star VY Canis Majoris

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    We report the detection of numerous far-infrared emission lines of water vapor toward the supergiant star VY Canis Majoris. A 29.5 - 45 micron grating scan of VY CMa, obtained using the Short Wavelength Spectrometer (SWS) of the Infrared Space Observatory (ISO) at a spectral resolving power of approximately 2000, reveals at least 41 spectral features due to water vapor that together radiate a total luminosity ~ 25 solar luminosities. In addition to pure rotational transitions within the ground vibrational state, these features include rotational transitions within the (010) excited vibrational state. The spectrum also shows the doublet Pi 1/2 (J=5/2) <-- doublet Pi 3/2 (J=3/2) OH feature near 34.6 micron in absorption. Additional SWS observations of VY CMa were carried out in the instrument's Fabry-Perot mode for three water transitions: the 7(25)-6(16) line at 29.8367 micron, the 4(41)-3(12) line 31.7721 micron, and the 4(32)-3(03) line at 40.6909 micron. The higher spectral resolving power of approximately 30,000 thereby obtained permits the line profiles to be resolved spectrally for the first time and reveals the "P Cygni" profiles that are characteristic of emission from an outflowing envelope.Comment: 11 pages (inc. 2 figures), LaTeX, uses aaspp4.sty, accepted for publication in ApJ Letter
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