277 research outputs found
Generation of Three-Qubit Entangled States using Superconducting Phase Qubits
Entanglement is one of the key resources required for quantum computation, so
experimentally creating and measuring entangled states is of crucial importance
in the various physical implementations of a quantum computer. In
superconducting qubits, two-qubit entangled states have been demonstrated and
used to show violations of Bell's Inequality and to implement simple quantum
algorithms. Unlike the two-qubit case, however, where all maximally-entangled
two-qubit states are equivalent up to local changes of basis, three qubits can
be entangled in two fundamentally different ways, typified by the states
and . Here we demonstrate the operation of three coupled
superconducting phase qubits and use them to create and measure
and states. The states are fully characterized
using quantum state tomography and are shown to satisfy entanglement witnesses,
confirming that they are indeed examples of three-qubit entanglement and are
not separable into mixtures of two-qubit entanglement.Comment: 9 pages, 5 figures. Version 2: added supplementary information and
fixed image distortion in Figure 2
Revising upper-ocean sulfur dynamics near Bermuda : new lessons from 3 years of concentration and rate measurements
© The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Environmental Chemistry 13 (2016): 302-313, doi:10.1071/EN15045.Oceanic biogeochemical cycling of dimethylsulfide (DMS), and its precursor dimethylsulfoniopropionate (DMSP), has gained considerable attention over the past three decades because of the potential role of DMS in climate mediation. Here we report 3 years of monthly vertical profiles of organic sulfur cycle concentrations (DMS, particulate DMSP (DMSPp) and dissolved DMSP (DMSPd)) and rates (DMSPd consumption, biological DMS consumption and DMS photolysis) from the Bermuda Atlantic Time-series Study (BATS) site taken between 2005 and 2008. Concentrations confirm the summer paradox with mixed layer DMS peaking ~90 days after peak DMSPp and ~50 days after peak DMSPp : Chl. A small decline in mixed layer DMS was observed relative to those measured during a previous study at BATS (1992–1994), potentially driven by long-term climate shifts at the site. On average, DMS cycling occurred on longer timescales than DMSPd (0.43 ± 0.35 v. 1.39 ± 0.76 day–1) with DMSPd consumption rates remaining elevated throughout the year despite significant seasonal variability in the bacterial DMSP degrader community. DMSPp was estimated to account for 4–5 % of mixed layer primary production and turned over at a significantly slower rate (~0.2 day–1). Photolysis drove DMS loss in the mixed layer during the summer, whereas biological consumption of DMS was the dominant loss process in the winter and at depth. These findings offer new insight into the underlying mechanisms driving DMS(P) cycling in the oligotrophic ocean, provide an extended dataset for future model evaluation and hypothesis testing and highlight the need for a reexamination of past modelling results and conclusions drawn from data collected with old methodologies.The authors acknowledge funding from the National Science Foundation
(NSF) (OCE-0425166) and the Center for Microbial Oceanography
Research and Education (CMORE) a NSF Science and Technology Center
(EF-0424599)
Systemic NK cell ablation attenuates intra‐abdominal adipose tissue macrophage infiltration in murine obesity
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108606/1/oby20823.pd
Rescaling multipartite entanglement measures for mixed states
A relevant problem regarding entanglement measures is the following: Given an
arbitrary mixed state, how does a measure for multipartite entanglement change
if general local operations are applied to the state? This question is
nontrivial as the normalization of the states has to be taken into account.
Here we answer it for pure-state entanglement measures which are invariant
under determinant 1 local operations and homogeneous in the state coefficients,
and their convex-roof extension which quantifies mixed-state entanglement. Our
analysis allows to enlarge the set of mixed states for which these important
measures can be calculated exactly. In particular, our results hint at a
distinguished role of entanglement measures which have homogeneous degree 2 in
the state coefficients.Comment: Published version plus one important reference (Ref. [39]
Distribution of calcifying and silicifying phytoplankton in relation to environmental and biogeochemical parameters during the late stages of the 2005 North East Atlantic Spring Bloom
The late stage of the North East Atlantic (NEA) spring bloom was investigated during June 2005 along a transect section from 45 to 66&deg; N between 15 and 20&deg; W in order to characterize the contribution of siliceous and calcareous phytoplankton groups and describe their distribution in relation to environmental factors. We measured several biogeochemical parameters such as nutrients, surface trace metals, algal pigments, biogenic silica (BSi), particulate inorganic carbon (PIC) or calcium carbonate, particulate organic carbon, nitrogen and phosphorus (POC, PON and POP, respectively), as well as transparent exopolymer particles (TEP). Results were compared with other studies undertaken in this area since the JGOFS NABE program. Characteristics of the spring bloom generally agreed well with the accepted scenario for the development of the autotrophic community. The NEA seasonal diatom bloom was in the late stages when we sampled the area and diatoms were constrained to the northern part of our transect, over the Icelandic Basin (IB) and Icelandic Shelf (IS). Coccolithophores dominated the phytoplankton community, with a large distribution over the Rockall-Hatton Plateau (RHP) and IB. The Porcupine Abyssal Plain (PAP) region at the southern end of our transect was the region with the lowest biomass, as demonstrated by very low Chl<i>a</i> concentrations and a community dominated by picophytoplankton. Early depletion of dissolved silicic acid (DSi) and increased stratification of the surface layer most likely triggered the end of the diatom bloom, leading to coccolithophore dominance. The chronic Si deficiency observed in the NEA could be linked to moderate Fe limitation, which increases the efficiency of the Si pump. TEP closely mirrored the distribution of both biogenic silica at depth and prymnesiophytes in the surface layer suggesting the sedimentation of the diatom bloom in the form of aggregates, but the relative contribution of diatoms and coccolithophores to carbon export in this area still needs to be resolved
Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer
AbstractAdipocytes promote progression of multiple cancers, but their role in pancreatic intraepithelial neoplasia (PanIN) and ductal adenocarcinoma (PDAC) is poorly defined. Nutrient transfer is a mechanism underlying stromal cell-cancer crosstalk. We studied the role of adipocytes in regulating in vitro PanIN and PDAC cell proliferation with a focus on glutamine metabolism. Murine 3T3L1 adipocytes were used to model adipocytes. Cell lines derived from PKCY mice were used to model PanIN and PDAC. Co-culture was used to study the effect of adipocytes on PanIN and PDAC cell proliferation in response to manipulation of glutamine metabolism. Glutamine secretion was measured with a bioanalyzer. Western blotting was used to study the effect of PanIN and PDAC cells on expression of glutamine-related enzymes in adipocytes. Adipocytes promote proliferation of PanIN and PDAC cells, an effect that was amplified in nutrient-poor conditions. Adipocytes secrete glutamine and rescue PanIN and PDAC cell proliferation in the absence of glutamine, an effect that was glutamine synthetase-dependent and involved PDAC cell-induced down-regulation of glutaminase expression in adipocytes. These findings suggest glutamine transfer as a potential mechanism underlying adipocyte-induced PanIN and PDAC cell proliferation
Effects of increased pCO2 and temperature on the North Atlantic spring bloom. III. Dimethylsulfoniopropionate
The CLAW hypothesis argues that a negative feedback mechanism involving phytoplankton- derived dimethylsulfoniopropionate (DMSP) could mitigate increasing sea surface temperatures that result from global warming. DMSP is converted to the climatically active dimethylsulfide (DMS), which is transferred to the atmosphere and photochemically oxidized to sulfate aerosols, leading to increases in planetary albedo and cooling of the Earth’s atmosphere. A shipboard incubation experiment was conducted to investigate the effects of increased temperature and pCO2 on the algal community structure of the North Atlantic spring bloom and their subsequent impact on particulate and dissolved DMSP concentrations (DMSPp and DMSPd). Under ‘greenhouse’ conditions (elevated pCO2; 690 ppm) and elevated temperature (ambient + 4°C), coccolithophorid and pelagophyte abundances were significantly higher than under control conditions (390 ppm CO2 and ambient temperature). This shift in phytoplankton community structure also resulted in an increase in DMSPp concentrations and DMSPp:chl a ratios. There were also increases in DMSP-lyase activity and biomass-normalized DMSP-lyase activity under ‘greenhouse’ conditions. Concentrations of DMSPd decreased in the ‘greenhouse’ treatment relative to the control. This decline is thought to be partly due to changes in the microzooplankton community structure and decreased grazing pressure under ‘greenhouse’ conditions. The increases in DMSPp in the high temperature and greenhouse treatments support the CLAW hypothesis; the declines in DMSPd do not
Trapped electron coupled to superconducting devices
We propose to couple a trapped single electron to superconducting structures
located at a variable distance from the electron. The electron is captured in a
cryogenic Penning trap using electric fields and a static magnetic field in the
Tesla range. Measurements on the electron will allow investigating the
properties of the superconductor such as vortex structure, damping and
decoherence. We propose to couple a superconducting microwave resonator to the
electron in order to realize a circuit QED-like experiment, as well as to
couple superconducting Josephson junctions or superconducting quantum
interferometers (SQUIDs) to the electron. The electron may also be coupled to a
vortex which is situated in a double well potential, realized by nearby pinning
centers in the superconductor, acting as a quantum mechanical two level system
that can be controlled by a transport current tilting the double well
potential. When the vortex is trapped in the interferometer arms of a SQUID,
this would allow its detection both by the SQUID and by the electron.Comment: 13 pages, 5 figure
An Open-System Quantum Simulator with Trapped Ions
The control of quantum systems is of fundamental scientific interest and
promises powerful applications and technologies. Impressive progress has been
achieved in isolating the systems from the environment and coherently
controlling their dynamics, as demonstrated by the creation and manipulation of
entanglement in various physical systems. However, for open quantum systems,
engineering the dynamics of many particles by a controlled coupling to an
environment remains largely unexplored. Here we report the first realization of
a toolbox for simulating an open quantum system with up to five qubits. Using a
quantum computing architecture with trapped ions, we combine multi-qubit gates
with optical pumping to implement coherent operations and dissipative
processes. We illustrate this engineering by the dissipative preparation of
entangled states, the simulation of coherent many-body spin interactions and
the quantum non-demolition measurement of multi-qubit observables. By adding
controlled dissipation to coherent operations, this work offers novel prospects
for open-system quantum simulation and computation.Comment: Pre-review submission to Nature. For an updated and final version see
publication. Manuscript + Supplementary Informatio
On the distance of the globular cluster M4 (NGC 6121) using RR Lyrae stars: I. optical and near-infrared Period-Luminosity and Period-Wesenheit relations
We present new distance determinations to the nearby globular M4 (NGC~6121)
based on accurate optical and Near Infrared (NIR) mean magnitudes for
fundamental (FU) and first overtone (FO) RR Lyrae variables (RRLs), and new
empirical optical and NIR Period-Luminosity (PL) and Period-Wesenheit (PW)
relations. We have found that optical-NIR and NIR PL and PW relations are
affected by smaller standard deviations than optical relations. The difference
is the consequence of a steady decrease in the intrinsic spread of cluster RRL
apparent magnitudes at fixed period as longer wavelengths are considered. The
weighted mean visual apparent magnitude of 44 cluster RRLs is
\left=13.329\pm0.001 (standard error of the mean) 0.177
(weighted standard deviation) mag. Distances were estimated using RR Lyr itself
to fix the zero-point of the empirical PL and PW relations. Using the entire
sample (FUFO) we found weighted mean true distance moduli of
11.350.030.05 mag and 11.320.020.07 mag. Distances were
also evaluated using predicted metallicity dependent PLZ and PWZ relations. We
found weighted mean true distance moduli of 11.2830.0100.018 mag (NIR
PLZ) and 11.2720.0050.019 mag (optical--NIR and NIR PWZ). The above
weighted mean true distance moduli agree within 1. The same result is
found from distances based on PWZ relations in which the color index is
independent of the adopted magnitude (11.2720.0040.013 mag). These
distances agree quite well with the geometric distance provided by
\citep{kaluzny2013} based on three eclipsing binaries. The available evidence
indicates that this approach can provide distances to globulars hosting RRLs
with a precision better than 2--3\%.Comment: Accepted for publication on Ap
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