47 research outputs found

    Surface-enhanced Raman spectroscopy study of 4-ATP on gold nanoparticles for basal cell carcinoma fingerprint detection

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    The surface-enhanced Raman signals of 4-aminothiophenol (4-ATP) attached to the surface of colloidal gold nanoparticles with size distribution of 2 to 5 nm were used as a labeling agent to detect basal cell carcinoma (BCC) of the skin. The enhanced Raman band at 1075 cm-1 corresponding to the C-S stretching vibration in 4-ATP was observed during attachment to the surface of the gold nanoparticles. The frequency and intensity of this band did not change when the colloids were conjugated with BerEP4 antibody, which speciïŹcally binds to BCC. We show the feasibility of imaging BCC by surface-enhanced Raman spectroscopy, scanning the 1075 cm-1 band to detect the distribution of 4ATP-coated gold nanoparticles attached to skin tissue ex vivo

    Use of Mangroves by Lemurs

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    Despite an increasing recognition of the ecosystem services provided by mangroves, we know little about their role in maintaining terrestrial biodiversity, including primates. Madagascar’s lemurs are a top global conservation priority with 94 % of species threatened with extinction, but records of their occurrence in mangroves are scarce. I used a mixed-methods approach to collect published and unpublished observations of lemurs in mangroves: I carried out a systematic literature search, and supplemented this with a targeted information request to 1243 researchers, conservation and tourism professionals and others who may have visited mangroves in Madagascar. I found references to, or observations of, at least 23 species in five families using mangroves, representing more than 20 % of lemur species and over 50 % of species whose distributions include mangrove areas. Lemurs used mangroves for foraging, sleeping and travelling between terrestrial forest patches, and some were observed as much as 3 km from the nearest permanently dry land. However most records were anecdotal and thus tell us little about lemur ecology in this habitat. Mangroves are more widely used by lemurs than has previously been recognised, and merit greater attention from primate researchers and conservationists in Madagascar

    ICAR: endoscopic skull‐base surgery

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    The dynamics of expanding mangroves in New Zealand

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    In contrast to the global trend of mangrove decline, New Zealand mangroves are rapidly expanding, facilitated by elevated sediment inputs in coastal waters as a consequence of large-scale land use changes following European settlement. New Zealand mangroves are at the southern limit of the global mangrove extent, which limits the tree height of Avicennia marina var. australasica, the only mangrove species present. Mangroves in New Zealand thrive in the sheltered environments of infilling drowned river valleys with abundant supply of fine terrigenous sediments, showing various stages of mangrove succession and expansion dynamics. Bio-physical interactions and carbon dynamics in these expanding temperate mangrove systems show similarities to, but also differ from those in tropical mangrove forests, for instance due to the limited height and complexity of the mangrove communities. Likewise, ecosystem services provided by New Zealand mangroves deviate from those offered by tropical mangroves. In particular, the association of mangrove expansion with the accumulation of (the increased supply of) fine sediments and the consequent change of estuarine ecosystems, has provoked a negative perception of mangrove expansion and subsequently led to mangrove clearance. Over recent decades, a body of knowledge has been developed regarding the planning and decision making relating to mangrove removal, yet there are still effects that are unknown, for example with respect to the post-clearance recovery of the original sandflat ecosystems. In this chapter we discuss the dynamics of New Zealand’s expanding mangroves from a range of viewpoints, with the aim of elucidating the possible contributions of expanding mangroves to coastal ecosystem services, now and in the future. This chapter also reviews current policies and practice regarding mangrove removal in New Zealand and addresses the (un)known effects of mangrove clearance. These combined insights may contribute to the development of integrated coastal management strategies that recognise the full potential of expanding mangrove ecosystems

    International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

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    Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

    Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies

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    IRDRC: An Intelligent Real-Time Dual-Functional Radar-Communication System for Automotive Vehicles

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    © 2012 IEEE. This letter introduces an intelligent Real-time Dual-functional Radar-Communication (iRDRC) system for autonomous vehicles (AVs). This system enables an AV to perform both radar and data communications functions to maximize bandwidth utilization as well as significantly enhance safety. In particular, the data communications function allows the AV to transmit data, e.g., of current traffic, to edge computing systems and the radar function is used to enhance the reliability and reduce the collision risks of the AV, e.g., under bad weather conditions. The problem of the iRDRC is to decide when to use the communication mode or the radar mode to maximize the data throughput while minimizing the miss detection probability of unexpected events given the uncertainty of surrounding environment. To solve the problem, we develop a deep reinforcement learning algorithm that allows the AV to quickly obtain the optimal policy without requiring any prior information about the environment. Simulation results show that the proposed scheme outperforms baseline schemes in terms of data throughput, miss detection probability, and convergence rate

    Radio Resource Management in Joint Radar and Communication: A Comprehensive Survey

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    Joint radar and communication (JRC) has recently attracted substantial attention. The first reason is that JRC allows individual radar and communication systems to share spectrum bands and thus improves the spectrum utilization. The second reason is that JRC enables a single hardware platform, e.g., an autonomous vehicle or a UAV, to simultaneously perform the communication function and the radar function. As a result, JRC is able to improve the efficiency of resources, i.e., spectrum and energy, reduce the system size, and minimize the system cost. However, there are several challenges to be solved for the JRC design. In particular, sharing the spectrum imposes the interference caused by the systems, and sharing the hardware platform and energy resource complicates the design of the JRC transmitter and compromises the performance of each function. To address the challenges, several resource management approaches have been recently proposed, and this paper presents a comprehensive literature review on resource management for JRC. First, we give fundamental concepts of JRC, important performance metrics used in JRC systems, and applications of the JRC systems. Then, we review and analyze resource management approaches, i.e., spectrum sharing, power allocation, and interference management, for JRC. In addition, we present security issues to JRC and provide a discussion of countermeasures to the security issues. Finally, we highlight important challenges in the JRC design and discuss future research directions related to JRC

    A Hierarchical Game Model for OFDM Integrated Radar and Communication Systems

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    This paper studies the spectrum allocation problem between spectrum service providers (SSPs) and terminals equipped with orthogonal frequency division multiplexing (OFDM) integrated radar and communication (IRC) systems. In particular, IRC-equipped terminals such as autonomous vehicles need to buy spectrum for their radar functions, e.g., sensing and detecting distant vehicles, and communication functions, e.g., transmitting sensing data to road-side units. The terminals determine their spectrum demands from the SSPs subject to their IRC performance requirements, while the SSPs compete with each other on the service prices to attract terminals. Taking into account the complicated interactions, a hierarchical Stackelberg game is proposed to reconcile the spectrum demand and service price, where the SSPs are the leaders and the terminals are the followers. Due to the spectrum constraints of the SSPs, we model the lower-layer subgame among the terminals as a generalized Nash equilibrium problem. An iterative searching algorithm is then developed that guarantees the convergence to the Stackelberg equilibrium. Numerical results demonstrate the effectiveness of our proposed scheme in terms of social welfare compared to baseline schemes

    Applications of Economic and Pricing Models for Wireless Network Security: A Survey

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    © 1998-2012 IEEE. This paper provides a comprehensive literature review on applications of economic and pricing theory to security issues in wireless networks. Unlike wireline networks, the broadcast nature and the highly dynamic change of network environments pose a number of nontrivial challenges to security design in wireless networks. While the security issues have not been completely solved by traditional or system-based solutions, economic and pricing models recently were employed as one efficient solution to discourage attackers and prevent attacks to be performed. In this paper, we review economic and pricing approaches proposed to address major security issues in wireless networks including eavesdropping attack, denial-of-service (DoS) attack such as jamming and distributed DoS, and illegitimate behaviors of malicious users. Additionally, we discuss integrating economic and pricing models with cryptography methods to reduce information privacy leakage as well as to guarantee the confidentiality and integrity of information in wireless networks. Finally, we highlight important challenges, open issues and future research directions of applying economic and pricing models to wireless security issues
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