70 research outputs found

    Quadrupole collectivity in neutron-rich Cd isotopes

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    4 pags., 2 figs. -- INPC 2013 – International Nuclear Physics ConferenceThe investigation of the excitation energies of the 21+ –states in the neutron-rich Cd isotopes shows an irregular behaviour when approaching the neutron shell-closure at N = 82. The energy of the 21+–state in 128Cd is lower than the one in 126Cd. The transition strength B(E2, 0gs+ → 21+) in the even isotopes 122−128Cd was measured in Coulomb excitation experiments with the high-purity germanium detector array MINIBALL at REXISOLDE (CERN). The values for 122,124Cd coincide with beyond-mean-field calculations with a resultant prolate deformation, whereas 126,128Cd are better described by shell-model calculations.This project is supported by BMBF (No. 06 DA 9036I, No. 05 P12 RDCIA, No. 05 P12 RDCIB and No. 05 P12 PKFNE), HIC for FAIR, EU through EURONS (No. 506065) and ENSAR (No. 262010) and the MINIBALL and REX-ISOLDE collaborations

    First EXL experiment with radioactive beam: Proton scattering on 56^{56}Ni

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    EXL (EXotic nuclei studied in Light-ion induced reactions at the NESR storage ring) is a project within NUSTAR at FAIR. It aims at investigations of light-ion induced direct reactions in inverse kinematics with radioactive ions cooled and stored in the future NESR (New Experimental Storage Ring). The existing ESR (Experimental Storage Ring) at GSI, together with its internal gas-jet target, provides a unique opportunity to perform such kind of experiments on a smaller scale at the present time. We have developed a UHV-compatible (Ultra High Vacuum) detector setup mainly based on DSSDs (Double-sided Silicon-Strip Detector) for the target-like recoils [4]. With this setup we were able to successfully investigate reactions with a stored radioactive beam for the first time ever. As a part of the first EXL campaign we investigated the reaction 56Ni(p,p)56Ni in inverse kinematics in order to measure the differential cross section for elastic proton scattering and deduce the nuclear-matter distribution and radius of 56Ni. In the following, the experimental setup is introduced in more detail, and the current status of the ongoing analysis is discussed

    Nuclear reactions in the storage ring ESR with EXL

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    The EXL project aims to study nuclear structure by direct reactions in inverse kinematics at the storage rings of the future FAIR facility. In this contribution, we present the status of the project: the technical implementation at the ESR at GSI and preliminary results of the EXL campaign in 2012, the first using also a radioactive beam

    Quadrupole collectivity in neutron-rich Cd isotopes

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    The investigation of the excitation energies of the 2(1)(+)-states in the neutron-rich Cd isotopes shows an irregular behaviour when approaching the neutron shell-closure at N = 82. The energy of the 2(1)(+)-state in Cd-128 is lower than the one in Cd-126. The transition strength B(E2, 0(gs)(+) -> 2(1)(+)) in the even isotopes Cd122-128 was measured in Coulomb excitation experiments with the high-purity germanium detector array MINIBALL at REX-ISOLDE (CERN). The values for Cd-122,Cd-124 coincide with beyond-mean-field calculations with a resultant prolate deformation, whereas Cd-126,Cd-128 are better described by shell-model calculations

    Profound increase in epinephrine concentration in plasma and cardiovascular stimulation after mu-opioid receptor blockade in opioid-addicted patients during barbiturate-induced anesthesia for acute detoxification

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    BACKGROUND: Acute displacement of opioids from their receptors by administration of large doses of opioid antagonists during general anesthesia is a new approach for detoxification of patients addicted to opioids. The authors tested the hypothesis that mu-opioid receptor blockade by naloxone induces cardiovascular stimulation mediated by the sympathoadrenal system. METHODS: Heart rate, cardiac index, and intravascular pressures were measured in 10 patients addicted to opioids (drug history; mean +/- SD, 71 +/- 51 months) during a program of methadone substitution (96 +/- 57 mg/day). Cardiovascular variables and concentrations of catecholamine in plasma were measured in the awake state, during methohexital-induced anesthesia (dose, 74 +/- 44 microg x kg(-1) x min(-1)) before administration of naloxone, and repeatedly during the first 3 h of mu-opioid receptor blockade. Naloxone was administered initially in an intravenous dose of 0.4 mg, followed by incremental bolus doses (0.8, 1.6, 3.2, and 6.4 mg) at 15-min intervals until a total dose of 12.4 mg had been administered within 60 min; administration was then continued by infusion (0.8 mg/h). RESULTS: Concentration of epinephrine in plasma increased 30-fold (15 +/- 9 to 458 +/- 304 pg/ml), whereas concentration of norepinephrine in plasma only increased to a minor extent (76 +/- 44 to 226 +/- 58 pg/ml, P <0.05). Cardiac index increased by 74% (2.7 +/- 0.41 to 4.7 +/- 1.7 min(-1) x m(-2)), because of increases in heart rate (89 +/- 16 to 108 +/- 17 beats/min) and stroke volume (+44%), reaching maximum 45 min after the initial injection of naloxone. In parallel, systemic vascular resistance index decreased (-40%). Systolic arterial pressure significantly increased (113 +/- 16 to 138 +/- 16 mmHg), whereas diastolic arterial pressure did not change. CONCLUSIONS: Despite barbiturate-induced anesthesia, acute mu-opioid receptor blockade in patients addicted to opioids induces profound epinephrine release and cardiovascular stimulation. These data suggest that long-term opioid receptor stimulation changes sympathoadrenal and cardiovascular function, which is acutely unmasked by mu-opioid receptor blockade. Because of the attendant cardiovascular stimulation, acute detoxification using naloxone should be performed by trained anesthesiologists or intensivist
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