1,500 research outputs found
Quantum computing with spatially delocalized qubits
We analyze the operation of quantum gates for neutral atoms with qubits that
are delocalized in space, i.e., the computational basis states are defined by
the presence of a neutral atom in the ground state of one out of two trapping
potentials. The implementation of single qubit gates as well as a controlled
phase gate between two qubits is discussed and explicit calculations are
presented for rubidium atoms in optical microtraps. Furthermore, we show how
multi-qubit highly entangled states can be created in this scheme.Comment: 4 pages, 4 figure
Quantum Logic Gates in Optical Lattices
We propose a new system for implementing quantum logic gates: neutral atoms
trapped in a very far-off-resonance optical lattice. Pairs of atoms are made to
occupy the same well by varying the polarization of the trapping lasers, and
then a near-resonant electric dipole is induced by an auxiliary laser. A
controlled-NOT can be implemented by conditioning the target atomic resonance
on a resolvable level shift induced by the control atom. Atoms interact only
during logical operations, thereby suppressing decoherence.Comment: Revised version, To appear in Phys. Rev. Lett. Three separate
postscript figure
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation
A recently discovered protein post-translational modification, lysine polyphosphorylation (K-PPn), consists of the covalent attachment of inorganic polyphosphate (polyP) to lysine residues. The non-enzymatic nature of K-PPn means that the degree of this modification depends on both polyP abundance and the amino acids surrounding the modified lysine. K-PPn was originally discovered in budding yeast (Saccharomyces cerevisiae), in which polyP anabolism and catabolism are well characterized. However, yeast vacuoles accumulate large amounts of polyP, and upon cell lysis, the release of the vacuolar polyP could non-physiologically cause K-PPn of nuclear and cytosolic targets. Moreover, yeast vacuoles possess two very active endopolyphosphatases, Ppn1 and Ppn2, that could have opposing effects on the extent of K-PPn. Here, we characterized the contribution of vacuolar polyP metabolism to K-PPn of two yeast proteins, Top1 (DNA topoisomerase 1) and Nsr1 (nuclear signal recognition 1). We discovered that whereas Top1-targeting K-PPn is only marginally affected by vacuolar polyP metabolism, Nsr1-targeting K-PPn is highly sensitive to the release of polyP and of endopolyphosphatases from the vacuole. Therefore, to better study K-PPn of cytosolic and nuclear targets, we constructed a yeast strain devoid of vacuolar polyP by targeting the exopolyphosphatase Ppx1 to the vacuole and concomitantly depleting the two endopolyphosphatases (ppn1Δppn2Δ, vt-Ppx1). This strain enabled us to study K-PPn of cytosolic and nuclear targets without the interfering effects of cell lysis on vacuole polyP and of endopolyphosphatases. Furthermore, we also define the fundamental nature of the acidic amino acid residues to the K-PPn target domain
What asteroseismology can do for exoplanets
We describe three useful applications of asteroseismology in the context of
exoplanet science: (1) the detailed characterisation of exoplanet host stars;
(2) the measurement of stellar inclinations; and (3) the determination of
orbital eccentricity from transit duration making use of asteroseismic stellar
densities. We do so using the example system Kepler-410 (Van Eylen et al.
2014). This is one of the brightest (V = 9.4) Kepler exoplanet host stars,
containing a small (2.8 Rearth) transiting planet in a long orbit (17.8 days),
and one or more additional non-transiting planets as indicated by transit
timing variations. The validation of Kepler-410 (KOI-42) was complicated due to
the presence of a companion star, and the planetary nature of the system was
confirmed after analyzing a Spitzer transit observation as well as ground-based
follow-up observations.Comment: 4 pages, Proceedings of the CoRoT Symposium 3 / Kepler KASC-7 joint
meeting, Toulouse, 7-11 July 2014. To be published by EPJ Web of Conference
Coherent manipulation of atomic qubits in optical micropotentials
We experimentally demonstrate the coherent manipulation of atomic states in
far-detuned dipole traps and registers of dipole traps based on two-dimensional
arrays of microlenses. By applying Rabi, Ramsey, and spin-echo techniques, we
systematically investigate the dephasing mechanisms and determine the coherence
time. Simultaneous Ramsey measurements in up to 16 dipole traps are performed
and proves the scalability of our approach. This represents an important step
in the application of scalable registers of atomic qubits for quantum
information processing. In addition, this system can serve as the basis for
novel atomic clocks making use of the parallel operation of a large number of
individual clocks each remaining separately addressable.Comment: to be published in Appl. Phys.
Detection of solar-like oscillations in relics of the Milky Way: asteroseismology of K giants in M4 using data from the NASA K2 mission
Asteroseismic constraints on K giants make it possible to infer radii, masses
and ages of tens of thousands of field stars. Tests against independent
estimates of these properties are however scarce, especially in the metal-poor
regime. Here, we report the detection of solar-like oscillations in 8 stars
belonging to the red-giant branch and red-horizontal branch of the globular
cluster M4. The detections were made in photometric observations from the K2
Mission during its Campaign 2. Making use of independent constraints on the
distance, we estimate masses of the 8 stars by utilising different combinations
of seismic and non-seismic inputs. When introducing a correction to the Delta
nu scaling relation as suggested by stellar models, for RGB stars we find
excellent agreement with the expected masses from isochrone fitting, and with a
distance modulus derived using independent methods. The offset with respect to
independent masses is lower, or comparable with, the uncertainties on the
average RGB mass (4-10%, depending on the combination of constraints used). Our
results lend confidence to asteroseismic masses in the metal poor regime. We
note that a larger sample will be needed to allow more stringent tests to be
made of systematic uncertainties in all the observables (both seismic and
non-seismic), and to explore the properties of RHB stars, and of different
populations in the cluster.Comment: 6 pages, 3 figures, accepted for publication in MNRA
Insulin and GH Signaling in Human Skeletal Muscle In Vivo following Exogenous GH Exposure: Impact of an Oral Glucose Load
GH induces acute insulin resistance in skeletal muscle in vivo, which in rodent models has been attributed to crosstalk between GH and insulin signaling pathways. Our objective was to characterize time course changes in signaling pathways for GH and insulin in human skeletal muscle in vivo following GH exposure in the presence and absence of an oral glucose load.Eight young men were studied in a single-blinded randomized crossover design on 3 occasions: 1) after an intravenous GH bolus 2) after an intravenous GH bolus plus an oral glucose load (OGTT), and 3) after intravenous saline plus OGTT. Muscle biopsies were taken at t = 0, 30, 60, and 120. Blood was sampled at frequent intervals for assessment of GH, insulin, glucose, and free fatty acids (FFA).GH increased AUC(glucose) after an OGTT (p<0.05) without significant changes in serum insulin levels. GH induced phosphorylation of STAT5 independently of the OGTT. Conversely, the OGTT induced acute phosphorylation of the insulin signaling proteins Akt (ser(473) and thr(308)), and AS160.The combination of OGTT and GH suppressed Akt activation, whereas the downstream expression of AS160 was amplified by GH. WE CONCLUDED THE FOLLOWING: 1) A physiological GH bolus activates STAT5 signaling pathways in skeletal muscle irrespective of ambient glucose and insulin levels 2) Insulin resistance induced by GH occurs without a distinct suppression of insulin signaling proteins 3) The accentuation of the glucose-stimulated activation of AS 160 by GH does however indicate a potential crosstalk between insulin and GH.ClinicalTrials.gov NCT00477997
Dynamical constants for electromagnetic fields with elliptic-cylindrical symmetry
Taking into account the characteristics of a free scalar field in elliptic
coordinates, a new dynamical variable is found for the free electromagnetic
field. The conservation law associated to this variable cannot be obtained by
direct application of standard Noether theorem since the symmetry generator is
of second order. Consequences on the expected mechanical behavior of an atomic
system interacting with electromagnetic waves exhibiting such a symmetry are
also discussed.Comment: 17 pages, 5 figures, revised version, animated graphs provided at
http://www.fisica.unam.mx/research/movie
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