Eritrocytic Parameters of the Blood of Calves with Different Birth Weights

In the conditions of a dairy farm with the help of the standard clinical, instrumental and laboratory methods the research on particularities of Eritrocytic parameters of the blood of calves (n=299) with different birth weights was carried out. It is shown that Holstein calves with normal intrauterine growth, born with body weight from 36.5 to 29 kg, have no reliable differences in red blood cell count. With a 1 kg reduction in body weight, there is a trend towards hyperchromia, but an increase in weight deficiency promotes of hypovolemia, hypochromia, and polycythaemia. In newborns with a body weight of 27.9–26.9 kg, polycythaemia is derived from hypovolemia, but, with a more pronounced weight deficiency, the role of erythrogenesis disorder in the pathogenesis of the syndrome increases. Hypochromia is a consequence of hematopoietic organs dysfunction and transmembrane loss of hemoglobin. Herein membrane destruction is caused by the increase in the content of toxical metabolites in the blood (sorptivity of red blood cells by 10–12 percent), and by a higher level of adrenaline (modification coefficient of membranes by adrenaline by 20–30 %). This indicates that the response of the fetus to the factors that inhibit its development is similar to a metabolic response against stress. At strong underweight body (b.w. less than 25 kg) exhausting of adaptive capability is observed with the increase in the blood level of toxical metabolites (sorptivity of red blood cells by 15 %), level of membrane destruction (level of ectoglobular hemoglobin in 2,8 times), and heterogeneity of red blood cells. Thus, in newborns with a body weight of less than 29 kg, the significant disturbances in the structure and functions of red blood cells were revealed, which gave grounds for stating that they had antenatal hypotrophy. Herewith, the severity of hematological changes depends on the degree of weight deficiency. Initially, it is hypovolemia and the resulting polycythemia, but, erythropoiesis disorders, and destruction of their membranes with increased polycythemia, and the development of hypochromia occur with the increasing severity of hypotrophy

Bipolaron Binding in Quantum Wires

A theory of bipolaron states in quantum wires with a parabolic potential well is developed applying the Feynman variational principle. The basic parameters of the bipolaron ground state (the binding energy, the number of phonons in the bipolaron cloud, the effective mass, and the bipolaron radius) are studied as a function of sizes of the potential well. Two cases are considered in detail: a cylindrical quantum wire and a planar quantum wire. Analytical expressions for the bipolaron parameters are obtained at large and small sizes of the quantum well. It is shown that at $R\gg 1$ [where $R$ means the radius (halfwidth) of a cylindrical (planar) quantum wire, expressed in Feynman units], the influence of confinement on the bipolaron binding energy is described by the function $\sim 1/R^{2}$ for both cases, while at small sizes this influence is different in each case. In quantum wires, the bipolaron binding energy $W(R)$ increases logarithmically with decreasing radius. The shapes and the sizes of a nanostructure, which are favorable for observation of stable bipolaron states, are determined.Comment: 17 pages, 6 figures, E-mail addresses: [email protected]; [email protected]

Трудности диагностики детского мультисистемного воспалительного синдрома, ассоциированного с COVID-19, в сочетании с ранней стадией первичной инфекции, вызванной вирусом Эпштейна-Барр

Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 is a rare life-threatening immunopathological complication of COVID-19 that develops 1-6 weeks after the acute coronavirus infection. MIS-C is characterized by fever and multiorgan inflammation.We present a clinical case of a 10-year-old boy with skin lesions at the onset of MIS-C (erythematous malar rash, lacelike rash on the trunk and extremities and petechiae) with macrophage activation syndrome development and the early stage of primary Epstein-Barr virus infection (EBV infection) which required the exclusion of X-linked lymphoproliferative disease.This clinical case demonstrates the complexity of diagnosis in MIS-C with skin manifestations at the onset of the disease, especially with concurrent activation of other infections, particularly EBV infection.Детский мультисистемный воспалительный синдром (ДМВС), ассоциированный с COVID-19 — это редкое жизнеугрожающее иммунопатологическое осложнение, развивающееся через 1-6 недель после перенесенной новой коронавирусной инфекции, протекающее с лихорадкой и мультиорганным воспалением.В статье представлено клиническое наблюдение мальчика в возрасте 10 лет с поражением кожи в дебюте ДМВС в виде полиморфной сыпи (эритема на щеках, сыпь в виде кружевного рисунка на туловище и конечностях, петехии), с одновременным обнаружением маркеров ранней стадии первичной инфекции, вызванной вирусом Эпштейна-Барр (ЭБВ), а также развитием гемофагоцитарного синдрома, что потребовало исключения Х-сцепленного лимфопролиферативного синдрома.Данное клиническое наблюдение демонстрирует сложность диагностического поиска при кожных проявлениях в дебюте ДМВС, а также возможность сочетания ДМВС с другими инфекциями, в частности с ЭБВ-инфекцией

Актуальні містобудівні моделі екологізації мегаполісів

Human had already understood all the disadvantages of consumer way of life. Nowadays there are a lot of countries where the realization of the principles of the sustainable development had begun. But planning of levels of the development has huge difficulties. It’s important to mix the forecasts of the scientists of different knowledge to get the one reasonable model of the human development. This tendentious give us the main courses of the planning ecological transformation of living space. Человечество, осознав безвыходность нынешнего потребительского способа. В настоящее время во многих странах началась реализация принципов устойчивого развития Но поэтапное планирование с учетом принципов устойчивого развития представляет собой большие трудности. Важно соединить прогнозы специалистов разных областей науки, чтобы получить единую обоснованную модель развития общества. Эти тенденции дают основные направления градостроительно -экологической трансформации среды. Людство зрозуміло безвихідність сучасного споживчого способу життя та взяло курс на триєдиний напрямок сталого розвитку. Але поетапне планування з урахуванням принципів сталого розвитку являє собою великі труднощі. Важливо з’єднати прогнози спеціалістів різних галузей знань, щоб отримати єдину обгунтовану модель розвитку суспільства. Ці тенденції дають основні напрямки містобудівної екологічної трансформації середовища