Properties of the a1 Meson from Lattice QCD

We determine the mass and decay constant of the $a_1$ meson using Monte Carlo simulation of lattice QCD. We find $M_{a_1} = 1250 \pm 80$ MeV and $f_{a_1} = 0.30 \pm 0.03 ~({\rm GeV})^2$, in good agreement with experiment.Comment: 9 page uu-encoded compressed postscript file. version appearing in Phys. Rev. Lett. 74 (1995) 459

Manifestation of Sea Quark Effects in the Strong Coupling Constant in Lattice QCD

We demonstrate that sea quark effects of a magnitude expected from renormalization group considerations are clearly visible in the strong coupling constant measured in current full QCD simulations. Building on this result an estimate of $\alpha_{\overline{MS}}^{(5)}(M_Z)$ is made employing the charmonium $1S-1P$ mass splitting calculated on full QCD configurations generated with two flavors of dynamical Kogut-Susskind quarks to fix the scale.Comment: 10 pages + 2 figures(postscript files), Latex files, compressed, uuencode tar file, UTHEP-28

Sea quark effects in B Spectroscopy and Decay Constants

We present comprehensive results for the spectrum and decay constants of hadrons containing a single b quark. The heavy quark is simulated using an $O(1/M)$ NRQCD action and the light quark using the $O(a)$ tadpole-improved clover action on gauge configurations containing two degenerate flavours of sea quarks at $\beta^{n_f=2}=5.6$ provided by the HEMCGC collaboration. We present detailed results for the lower lying $S$ and $P$ wave $B$ meson states and the $\Lambda_b$ baryon. We find broad agreement with experiment. In addition, we present results for the pseudoscalar and, for the first time, the vector decay constants fully consistent to $O(\alpha/M): f_B = 186(5)(stat)(19)(pert)(9)(disc)(13)(NRQCD)(+50)(a^{-1})MeV, f_B^* = 181(6) (stat)(18)(pert)(9)(disc)(13)(NRQCD)(+55)(a^{-1})MeV$ and $f_{B_s}/f_B = 1.14(2)(stat)(-2)(\kappa_s)$. We present an investigation of sea quark effects in the $B$ spectrum and decay constants. We compare our results with those from similar quenched simulations at $\beta^{n_f=0}=6.0$. For the spectrum, the quenched results reproduce the experimental spectrum well and there is no significant difference between the quenched and $n_f=2$ results. For the decay constants, our results suggest that sea quark effects may be large. We find that $f_B$ increases by approximately 25% between $n_f=0$ and $n_f=2$.Comment: 49 pages, 16 figures, revtex, the discussion of systematic errors and the comparison of the pseudoscalar decay constant at nf=0 and nf=2 has been expande

Lattice Calculation of Heavy-Light Decay Constants with Two Flavors of Dynamical Quarks

We present results for $f_B$, $f_{B_s}$, $f_D$, $f_{D_s}$ and their ratios in the presence of two flavors of light sea quarks ($N_f=2$). We use Wilson light valence quarks and Wilson and static heavy valence quarks; the sea quarks are simulated with staggered fermions. Additional quenched simulations with nonperturbatively improved clover fermions allow us to improve our control of the continuum extrapolation. For our central values the masses of the sea quarks are not extrapolated to the physical $u$, $d$ masses; that is, the central values are "partially quenched." A calculation using "fat-link clover" valence fermions is also discussed but is not included in our final results. We find, for example, $f_B = 190 (7) (^{+24}_{-17}) (^{+11}_{-2}) (^{+8}_{-0})$ MeV, $f_{B_s}/f_B = 1.16 (1) (2) (2) (^{+4}_{-0})$, $f_{D_s} = 241 (5) (^{+27}_{-26}) (^{+9}_{-4}) (^{+5}_{-0})$ MeV, and $f_{B}/f_{D_s} = 0.79 (2) (^{+5}_{-4}) (3) (^{+5}_{-0})$, where in each case the first error is statistical and the remaining three are systematic: the error within the partially quenched $N_f=2$ approximation, the error due to the missing strange sea quark and to partial quenching, and an estimate of the effects of chiral logarithms at small quark mass. The last error, though quite significant in decay constant ratios, appears to be smaller than has been recently suggested by Kronfeld and Ryan, and Yamada. We emphasize, however, that as in other lattice computations to date, the lattice $u,d$ quark masses are not very light and chiral log effects may not be fully under control.Comment: Revised version includes an attempt to estimate the effects of chiral logarithms at small quark mass; central values are unchanged but one more systematic error has been added. Sections III E and V D are completely new; some changes for clarity have also been made elsewhere. 82 pages; 32 figure

Lattice Determination of Heavy-Light Decay Constants

We report on the MILC collaboration's calculation of $f_B$, $f_{B_s}$, $f_D$, $f_{D_s}$, and their ratios. Our central values come from the quenched approximation, but the quenching error is estimated from $N_F=2$ dynamical staggered lattices. We use Wilson light valence quarks and Wilson and static heavy quarks. We find, for example, f_B=157 \pm 11 {}^{+25}_{-9} {}^{+23}_{-0} \MeV, $f_{B_s}/f_B = 1.11 \pm 0.02 {}^{+0.04}_{-0.03} \pm 0.03$, f_{D_s} = 210 \pm 9 {}^{+25}_{-9} {}^{+17}_{-1} \MeV and $f_{B}/f_{D_s} = 0.75 \pm 0.03 {}^{+0.04}_{-0.02} {}^{+0.08}_{-0.00}$, where the errors are statistical, systematic (within the quenched approximation), and systematic (of quenching), respectively.Comment: 4 pages, 2 included figures. We adjust the perturbative correction calculated by Kuramashi to take into account the fact that we match to the continuum at the kinetic mass of the heavy meson, not the pole mass. This produces a 2 to 4 MeV change in final results for decay constants, and has negligible effect on decay constant ratios. We also include further explanation of various features of the analysi

Comparative Study of full QCD Hadron Spectrum and Static Quark Potential with Improved Actions

We investigate effects of action improvement on the light hadron spectrum and the static quark potential in two-flavor QCD for $a^{-1} \approx 1$ GeV and $m_{PS}/m_V = 0.7-0.9$. We compare a renormalization group improved action with the plaquette action for gluons, and the SW-clover action with the Wilson action for quarks. We find a significant improvement in the hadron spectrum by improving the quark action, while the gluon improvement is crucial for a rotationally invariant static potential. We also explore the region of light quark masses corresponding to $m_{PS}/m_V \geq 0.4$ on a 2.7 fm lattice using the improved gauge and quark action. A flattening of the potential is not observed up to 2 fm.Comment: LaTeX, 35 pages, 22 eps figures, uses revtex and eps

Aging of the mammalian gastrointestinal tract: a complex organ system

Gastrointestinal disorders are a major cause of morbidity in the elderly population. The gastrointestinal tract is the most complex organ system; its diverse cells perform a range of functions essential to life, not only secretion, digestion, absorption and excretion, but also, very importantly, defence. The gastrointestinal tract acts not only as a barrier to harmful materials and pathogens but also contains the vast number of beneficial bacterial populations that make up the microbiota. Communication between the cells of the gastrointestinal tract and the central nervous and endocrine systems modifies behaviour; the organisms of the microbiota also contribute to this brain–gut–enteric microbiota axis. Age-related physiological changes in the gut are not only common, but also variable, and likely to be influenced by external factors as well as intrinsic aging of the cells involved. The cellular and molecular changes exhibited by the aging gut cells also vary. Aging intestinal smooth muscle cells exhibit a number of changes in the signalling pathways that regulate contraction. There is some evidence for age-associated degeneration of neurons and glia of the enteric nervous system, although enteric neuronal losses are likely not to be nearly as extensive as previously believed. Aging enteric neurons have been shown to exhibit a senescence-associated phenotype. Epithelial stem cells exhibit increased mitochondrial mutation in aging that affects their progeny in the mucosal epithelium. Changes to the microbiota and intestinal immune system during aging are likely to contribute to wider aging of the organism and are increasingly important areas of analysis. How changes of the different cell types of the gut during aging affect the numerous cellular interactions that are essential for normal gut functions will be important areas for future aging research

Relationship between the population incidence of febrile convulsions in young children in Sydney, Australia and seasonal epidemics of influenza and respiratory syncytial virus, 2003-2010: a time series analysis

<p>Abstract</p> <p>Background</p> <p>In 2010, intense focus was brought to bear on febrile convulsions in Australian children particularly in relation to influenza vaccination. Febrile convulsions are relatively common in infants and can lead to hospital admission and severe outcomes. We aimed to examine the relationships between the population incidence of febrile convulsions and influenza and respiratory syncytial virus (RSV) seasonal epidemics in children less than six years of age in Sydney Australia using routinely collected syndromic surveillance data and to assess the feasibility of using this data to predict increases in population rates of febrile convulsions.</p> <p>Methods</p> <p>Using two readily available sources of routinely collected administrative data; the NSW Emergency Department (ED) patient management database (1 January 2003 - 30 April 2010) and the Ambulance NSW dispatch database (1 July 2006 - 30 April 2010), we used semi-parametric generalized additive models (GAM) to determine the association between the population incidence rate of ED presentations and urgent ambulance dispatches for 'convulsions', and the population incidence rate of ED presentations for 'influenza-like illness' (ILI) and 'bronchiolitis' - proxy measures of influenza and RSV circulation, respectively.</p> <p>Results</p> <p>During the study period, when the weekly all-age population incidence of ED presentations for ILI increased by 1/100,000, the 0 to 6 year-old population incidence of ED presentations for convulsions increased by 6.7/100,000 (P < 0.0001) and that of ambulance calls for convulsions increased by 3.2/100,000 (P < 0.0001). The increase in convulsions occurred one week earlier relative to the ED increase in ILI. The relationship was weaker during the epidemic of pandemic (H1N1) 2009 influenza virus.</p> <p>When the 0 to 3 year-old population incidence of ED presentations for bronchiolitis increased by 1/100,000, the 0 to 6 year-old population incidence of ED presentations for convulsions increased by 0.01/100,000 (P < 0.01). We did not find a meaningful and statistically significant association between bronchiolitis and ambulance calls for convulsions.</p> <p>Conclusions</p> <p>Influenza seasonal epidemics are associated with a substantial and statistically significant increase in the population incidence of hospital attendances and ambulance dispatches for reported febrile convulsions in young children. Monitoring syndromic ED and ambulance data facilitates rapid surveillance of reported febrile convulsions at a population level.</p

European Red List of Habitats Part 1. Marine habitats

The European Red List of Habitats provides an overview of the risk of collapse (degree of endangerment) of marine, terrestrial and freshwater habitats in the European Union (EU28) and adjacent regions (EU28+), based on a consistent set of categories and criteria, and detailed data and expert knowledge from involved countries1. A total of 257 benthic marine habitat types were assessed. In total, 19% (EU28) and 18% (EU28+) of the evaluated habitats were assessed as threatened in categories Critically Endangered, Endangered and Vulnerable. An additional 12% were Near Threatened in the EU28 and 11% in the EU28+. These figures are approximately doubled if Data Deficient habitats are excluded. The percentage of threatened habitat types differs across the regional seas. The highest proportion of threatened habitats in the EU28 was found in the Mediterranean Sea (32%), followed by the North-East Atlantic (23%), the Black Sea (13%) and then the Baltic Sea (8%). There was a similar pattern in the EU28+. The most frequently cited pressures and threats were similar across the four regional seas: pollution (eutrophication), biological resource use other than agriculture or forestry (mainly fishing but also aquaculture), natural system modifications (e.g. dredging and sea defence works), urbanisation and climate change. Even for habitats where the assessment outcome was Data Deficient, the Red List assessment process has resulted in the compilation of a substantial body of useful information to support the conservation of marine habitats