486 research outputs found
Ondes hydrothermales non-linéaires dans un disque et un anneau
URL: http://www-spht.cea.fr/articles/S98/109Nous nous intéressons à la convection thermocapillaire, produite par l'imposition d'un gradient {\it horizontal} de température sur une mince couche de fluide avec surface libre. En géométrie bidimensionnelle nous observons deux modes différents en compétition, tandis qu'en géométrie bidimensionnelle avec conditions limites périodiques, nous étudions la transition à la turbulence d'une onde propagative homogène
On the decay of turbulence in plane Couette flow
The decay of turbulent and laminar oblique bands in the lower transitional
range of plane Couette flow is studied by means of direct numerical simulations
of the Navier--Stokes equations. We consider systems that are extended enough
for several bands to exist, thanks to mild wall-normal under-resolution
considered as a consistent and well-validated modelling strategy. We point out
a two-stage process involving the rupture of a band followed by a slow
regression of the fragments left. Previous approaches to turbulence decay in
wall-bounded flows making use of the chaotic transient paradigm are
reinterpreted within a spatiotemporal perspective in terms of large deviations
of an underlying stochastic process.Comment: ETC13 Conference Proceedings, 6 pages, 5 figure
Transient growth in Taylor-Couette flow
Transient growth due to non-normality is investigated for the Taylor-Couette
problem with counter-rotating cylinders as a function of aspect ratio eta and
Reynolds number Re. For all Re < 500, transient growth is enhanced by
curvature, i.e. is greater for eta < 1 than for eta = 1, the plane Couette
limit. For fixed Re < 130 it is found that the greatest transient growth is
achieved for eta between the Taylor-Couette linear stability boundary, if it
exists, and one, while for Re > 130 the greatest transient growth is achieved
for eta on the linear stability boundary. Transient growth is shown to be
approximately 20% higher near the linear stability boundary at Re = 310, eta =
0.986 than at Re = 310, eta = 1, near the threshold observed for transition in
plane Couette flow. The energy in the optimal inputs is primarily meridional;
that in the optimal outputs is primarily azimuthal. Pseudospectra are
calculated for two contrasting cases. For large curvature, eta = 0.5, the
pseudospectra adhere more closely to the spectrum than in a narrow gap case,
eta = 0.99
Electronic temperatures, densities and plasma X-ray emission of a 14.5 GHz Electron-Cyclotron Resonance Ion Source
We have performed a systematic study of the Bremsstrahlung emission from the
electrons in the plasma of a commercial 14.5 GHz Electron-Cyclotron Resonance
Ion Source. The electronic spectral temperature and the product of ionic and
electronic densities of the plasma are measured by analyzing the Bremsstrahlung
spectra recorded for several rare gases (Ar, Kr, Xe) as a function of the
injected power. Within our uncertainty, we find an average temperature of ? 48
keV above 100W, with a weak dependency on the injected power and gas
composition. Charge state distributions of extracted ion beams have been
determined as well, providing a way to disentangle the ionic density from the
electronic density. Moreover X-ray emission from highly charged argon ions in
the plasma has been observed with a high-resolution mosaic crystal
spectrometer, demonstrating the feasibility for high-precision measurements of
transition energies of highly charged ions, in particular of the magnetic
dipole (M1) transition of He-like of argon ions
Rapid assembly of a polar network architecture drives efficient actomyosin contractility
Actin network architecture and dynamics play a central role in cell contractility and tissue morphogenesis. RhoA-driven pulsed contractions are a generic mode of actomyosin contractility, but the mechanisms under- lying how their specific architecture emerges and how this architecture supports the contractile function of the network remain unclear. Here we show that, during pulsed contractions, the actin network is assembled by two subpopulations of formins: a functionally inactive population (recruited) and formins actively partici- pating in actin filament elongation (elongating). We then show that elongating formins assemble a polar actin network, with barbed ends pointing out of the pulse. Numerical simulations demonstrate that this geometry favors rapid network contraction. Our results show that formins convert a local RhoA activity gradient into a polar network architecture, causing efficient network contractility, underlying the key function of kinetic con- trols in the assembly and mechanics of cortical network architectures
II Congrés Internacional sobre Traducció : abril 1994 : actes
Machine learning-based approach unravels distinct pathological signatures induced by patient-derived α-synuclein seeds in monkeys. Dopaminergic neuronal cell death, associated with intracellular α-synuclein (α-syn)-rich protein aggregates [termed "Lewy bodies" (LBs)], is a well-established characteristic of Parkinson's disease (PD). Much evidence, accumulated from multiple experimental models, has suggested that α-syn plays a role in PD pathogenesis, not only as a trigger of pathology but also as a mediator of disease progression through pathological spreading. Here, we have used a machine learning-based approach to identify unique signatures of neurodegeneration in monkeys induced by distinct α-syn pathogenic structures derived from patients with PD. Unexpectedly, our results show that, in nonhuman primates, a small amount of singular α-syn aggregates is as toxic as larger amyloid fibrils present in the LBs, thus reinforcing the need for preclinical research in this species. Furthermore, our results provide evidence supporting the true multifactorial nature of PD, as multiple causes can induce a similar outcome regarding dopaminergic neurodegeneratio
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