Effect of Blood Ph and CO2 Tension on the Performance of the Heart-lung Preparation

Blood pH and carbon dioxide tension effect on performance of heart-lung preparatio

Effect of hypoxia on myocardium in heart-lung preparation

Effect of hypoxia on myocardium in starling heart lung preparations ventilated with mixtures of oxygen, nitrogen, and carbon dioxid

Cardiac output and regional blood flow in conscious rats exposed to acute hypoxia

Cardiac output and regional blood flow in conscious rats exposed to acute hypoxi

Comment on ``Method to analyze electromechanical stability of dielectric elastomers" [Appl. Phys. Lett. 91, 061921 (2007)]

The model of Zhao and Suo can be readily generalized to predict the critical breakdown electric field $E_c$ value of elastomers with arbitrary elastic strain energy function. An explicit expression for $E_c$ is presented for elastomeric thin films under biaxial strain and comparisons are made with experimental data using a two term Ogden rubber elasticity model. Simplified results for uniaxial and for equi-biaxial stress provide further insight into the findings of Zhao and Suo.Comment: 2 page

Employing pre-stress to generate finite cloaks for antiplane elastic waves

It is shown that nonlinear elastic pre-stress of neo-Hookean hyperelastic materials can be used as a mechanism to generate finite cloaks and thus render objects near-invisible to incoming antiplane elastic waves. This approach appears to negate the requirement for special cloaking metamaterials with inhomogeneous and anisotropic material properties in this case. These properties are induced naturally by virtue of the pre-stress. This appears to provide a mechanism for broadband cloaking since dispersive effects due to metamaterial microstructure will not arise.Comment: 4 pages, 2 figure

A test of spray nozzles

Cover title.Also continuously numbered from previous Bulletin (p. 88-115) on upper outside corner.The height of spray -- Shape and density of spray -- Size of drops -- Amount of discharge -- Clogging -- Dribbling -- Durability -- Method of attachment

Defining end user requirements for a field-based molecular detection system for wildlife forensic investigations

The increasing use of non-laboratory-based DNA and protein detection methods promise to provide rapid investigative intelligence and support sample prioritisation. Primarily developed for human forensic or medical applications, current systems may also show utility in the field of wildlife forensic science. However, it is currently unknown whether the requirements of the wildlife forensic community can be met by current non-laboratory based tools. Given the diverse array of stakeholders and sample types commonly encountered, it is necessary to first identify the needs of the community and then try and map their needs to current instrumentation. By using a market research style questionnaire, this study identified key requirements for a non-laboratory-based system following feedback from the wildlife forensic community. Data showed that there is strong support for field-based detection methods while highlighting concerns including contamination risks and reduced quality assurance associated with non-laboratory testing. Key species and applications were identified alongside hurdles to implementation and adoption. Broadly, the requirements align with many of the developmental drivers that have led to the rise of in-field portable detection instrumentation, specifically rapid detection within one hour, ease-of-use, and ≥95% accuracy. Several existing platforms exist that met some of the identified requirements but not all. With further collaboration between industry partners and the wildlife forensic community it is possible that new field-based systems can be developed and applied routinely

The Effects of Caffeine on Maximal Anaerobic Exercise

Please view abstract in the attached PDF file

Mutational analysis of residues involved in nucleotide and divalent cation stabilization in the rotavirus RNA-dependent RNA polymerase catalytic pocket

AbstractThe rotavirus RNA-dependent RNA polymerase (RdRp), VP1, contains canonical RdRp motifs and a priming loop that is hypothesized to undergo conformational rearrangements during RNA synthesis. In the absence of viral core shell protein VP2, VP1 fails to interact stably with divalent cations or nucleotides and has a retracted priming loop. To identify residues of potential import to nucleotide and divalent cation stabilization, we aligned VP1 of divergent rotaviruses and the structural homolog reovirus λ3. VP1 mutants were engineered and characterized for RNA synthetic capacity in vitro. Conserved aspartic acids in RdRp motifs A and C and arginines in motif F that likely stabilize divalent cations and nucleotides were required for efficient RNA synthesis. Mutation of individual priming loop residues diminished or enhanced RNA synthesis efficiency without obviating the need for VP2, which suggests that this structure serves as a dynamic regulatory element that links RdRp activity to particle assembly