4,461 research outputs found
Effect of Blood Ph and CO2 Tension on the Performance of the Heart-lung Preparation
Blood pH and carbon dioxide tension effect on performance of heart-lung preparatio
Effect of hypoxia on myocardium in heart-lung preparation
Effect of hypoxia on myocardium in starling heart lung preparations ventilated with mixtures of oxygen, nitrogen, and carbon dioxid
Cardiac output and regional blood flow in conscious rats exposed to acute hypoxia
Cardiac output and regional blood flow in conscious rats exposed to acute hypoxi
Comment on ``Method to analyze electromechanical stability of dielectric elastomers" [Appl. Phys. Lett. 91, 061921 (2007)]
The model of Zhao and Suo can be readily generalized to predict the critical
breakdown electric field value of elastomers with arbitrary elastic
strain energy function. An explicit expression for is presented for
elastomeric thin films under biaxial strain and comparisons are made with
experimental data using a two term Ogden rubber elasticity model. Simplified
results for uniaxial and for equi-biaxial stress provide further insight into
the findings of Zhao and Suo.Comment: 2 page
Employing pre-stress to generate finite cloaks for antiplane elastic waves
It is shown that nonlinear elastic pre-stress of neo-Hookean hyperelastic
materials can be used as a mechanism to generate finite cloaks and thus render
objects near-invisible to incoming antiplane elastic waves. This approach
appears to negate the requirement for special cloaking metamaterials with
inhomogeneous and anisotropic material properties in this case. These
properties are induced naturally by virtue of the pre-stress. This appears to
provide a mechanism for broadband cloaking since dispersive effects due to
metamaterial microstructure will not arise.Comment: 4 pages, 2 figure
A test of spray nozzles
Cover title.Also continuously numbered from previous Bulletin (p. 88-115) on upper outside corner.The height of spray -- Shape and density of spray -- Size of drops -- Amount of discharge -- Clogging -- Dribbling -- Durability -- Method of attachment
An experimental investigation of the effects of subsurface drains on beach stabilization, October 1991, 98p
Defining end user requirements for a field-based molecular detection system for wildlife forensic investigations
The increasing use of non-laboratory-based DNA and protein detection methods promise to provide rapid investigative intelligence and support sample prioritisation. Primarily developed for human forensic or medical applications, current systems may also show utility in the field of wildlife forensic science. However, it is currently unknown whether the requirements of the wildlife forensic community can be met by current non-laboratory based tools. Given the diverse array of stakeholders and sample types commonly encountered, it is necessary to first identify the needs of the community and then try and map their needs to current instrumentation. By using a market research style questionnaire, this study identified key requirements for a non-laboratory-based system following feedback from the wildlife forensic community. Data showed that there is strong support for field-based detection methods while highlighting concerns including contamination risks and reduced quality assurance associated with non-laboratory testing. Key species and applications were identified alongside hurdles to implementation and adoption. Broadly, the requirements align with many of the developmental drivers that have led to the rise of in-field portable detection instrumentation, specifically rapid detection within one hour, ease-of-use, and ≥95% accuracy. Several existing platforms exist that met some of the identified requirements but not all. With further collaboration between industry partners and the wildlife forensic community it is possible that new field-based systems can be developed and applied routinely
The Effects of Caffeine on Maximal Anaerobic Exercise
Please view abstract in the attached PDF file
Mutational analysis of residues involved in nucleotide and divalent cation stabilization in the rotavirus RNA-dependent RNA polymerase catalytic pocket
AbstractThe rotavirus RNA-dependent RNA polymerase (RdRp), VP1, contains canonical RdRp motifs and a priming loop that is hypothesized to undergo conformational rearrangements during RNA synthesis. In the absence of viral core shell protein VP2, VP1 fails to interact stably with divalent cations or nucleotides and has a retracted priming loop. To identify residues of potential import to nucleotide and divalent cation stabilization, we aligned VP1 of divergent rotaviruses and the structural homolog reovirus λ3. VP1 mutants were engineered and characterized for RNA synthetic capacity in vitro. Conserved aspartic acids in RdRp motifs A and C and arginines in motif F that likely stabilize divalent cations and nucleotides were required for efficient RNA synthesis. Mutation of individual priming loop residues diminished or enhanced RNA synthesis efficiency without obviating the need for VP2, which suggests that this structure serves as a dynamic regulatory element that links RdRp activity to particle assembly
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