4,147 research outputs found
Stability of complex hyperbolic space under curvature-normalized Ricci flow
Using the maximal regularity theory for quasilinear parabolic systems, we
prove two stability results of complex hyperbolic space under the
curvature-normalized Ricci flow in complex dimensions two and higher. The first
result is on a closed manifold. The second result is on a complete noncompact
manifold. To prove both results, we fully analyze the structure of the
Lichnerowicz Laplacian on complex hyperbolic space. To prove the second result,
we also define suitably weighted little H\"{o}lder spaces on a complete
noncompact manifold and establish their interpolation properties.Comment: Some typos in version 2 are correcte
Proton decay from the isoscalar giant dipole resonance in Ni
Proton decay from the 3 isoscalar giant dipole resonance (ISGDR)
in Ni has been measured using the () reaction at a
bombarding energy of 386 MeV to investigate its decay properties. We have
extracted the ISGDR strength under the coincidence condition between
inelastically scattered particles at forward angles and decay protons
emitted at backward angles. Branching ratios for proton decay to low-lying
states of Co have been determined, and the results compared to
predictions of recent continuum-RPA calculations. The final-state spectra of
protons decaying to the low-lying states in Co were analyzed for a more
detailed understanding of the structure of the ISGDR. It is found that there
are differences in the structure of the ISGDR as a function of excitation
energy.Comment: Minor changes after review. Accepted for publication in Phys. Rev. C.
19 pages; 7 figure
Isotopic dependence of the giant monopole resonance in the even-A ^{112-124}Sn isotopes and the asymmetry term in nuclear incompressibility
The strength distributions of the giant monopole resonance (GMR) have been
measured in the even-A Sn isotopes (A=112--124) with inelastic scattering of
400-MeV particles in the angular range
--. We find that the experimentally-observed GMR energies
of the Sn isotopes are lower than the values predicted by theoretical
calculations that reproduce the GMR energies in Pb and Zr very
well. From the GMR data, a value of MeV is obtained
for the asymmetry-term in the nuclear incompressibility.Comment: Submitted to Physical Review Letters. 10 pages; 4 figure
Uncomputably noisy ergodic limits
V'yugin has shown that there are a computable shift-invariant measure on
Cantor space and a simple function f such that there is no computable bound on
the rate of convergence of the ergodic averages A_n f. Here it is shown that in
fact one can construct an example with the property that there is no computable
bound on the complexity of the limit; that is, there is no computable bound on
how complex a simple function needs to be to approximate the limit to within a
given epsilon
Methylation of the KEAP1 gene promoter region in human colorectal cancer
<p>Abstract</p> <p>Background</p> <p>The Keap1-Nrf2 pathway has been reported to be impaired in several cancers. However, the status of Keap1-Nrf2 system in human colorectal cancer (CRC) has not been elucidated.</p> <p>Methods</p> <p>We used colorectal cancer (CRC) cell lines and surgical specimens to investigate the methylation status of the <it>KEAP1 </it>promoter region as well as expression of Nrf2 and its downstream antioxidative stress genes, <it>NQO-1 </it>and <it>AKR1C1</it>.</p> <p>Results</p> <p>DNA sequencing analysis indicated that all mutations detected were synonymous, with no amino acid substitutions. We showed by bisulfite genomic sequencing and methylation-specific PCR that eight of 10 CRC cell lines had hypermethylated CpG islands in the <it>KEAP1 </it>promoter region. HT29 cells with a hypermethylated <it>KEAP1 </it>promoter resulted in decreased mRNA and protein expression but unmethylated Colo320DM cells showed higher expression levels. In addition, treatment with the DNA methyltransferase inhibitor 5-Aza-dC combined with the histone deacetylase inhibitor trichostatin A (TSA) increased <it>KEAP1 </it>mRNA expression. These result suggested that methylation of the <it>KEAP1 </it>promoter regulates its mRNA level. Time course analysis with the Nrf2-antioxidant response element (ARE) pathway activator t-BHQ treatment showed a rapid response within 24 h. HT29 cells had higher basal expression levels of <it>NQO-1 </it>and <it>AKR1C1 </it>mRNA than Colo320DM cells. Aberrant promoter methylation of <it>KEAP1 </it>was detected in 53% of tumor tissues and 25% of normal mucosae from 40 surgical CRC specimens, indicating that cancerous tissue showed increased methylation of the <it>KEAP1 </it>promoter region, conferring a protective effect against cytotoxic anticancer drugs.</p> <p>Conclusion</p> <p>Hypermethylation of the <it>KEAP1 </it>promoter region suppressed its mRNA expression and increased nuclear Nrf2 and downstream ARE gene expression in CRC cells and tissues.</p
Recent Advances in Modeling Stellar Interiors
Advances in stellar interior modeling are being driven by new data from
large-scale surveys and high-precision photometric and spectroscopic
observations. Here we focus on single stars in normal evolutionary phases; we
will not discuss the many advances in modeling star formation, interacting
binaries, supernovae, or neutron stars. We review briefly: 1) updates to input
physics of stellar models; 2) progress in two and three-dimensional evolution
and hydrodynamic models; 3) insights from oscillation data used to infer
stellar interior structure and validate model predictions (asteroseismology).
We close by highlighting a few outstanding problems, e.g., the driving
mechanisms for hybrid gamma Dor/delta Sct star pulsations, the cause of giant
eruptions seen in luminous blue variables such as eta Car and P Cyg, and the
solar abundance problem.Comment: Proceedings for invited talk at conference High Energy Density
Laboratory Astrophysics 2010, Caltech, March 2010, submitted for special
issue of Astrophysics and Space Science; 7 pages; 5 figure
Palladium nanoparticles by electrospinning from poly(acrylonitrile-co-acrylic acid)-PdCl2 solutions. Relations between preparation conditions, particle size, and catalytic activity
Catalytic palladium (Pd) nanoparticles on electrospun copolymers of acrylonitrile and acrylic acid (PAN-AA) mats were produced via reduction of PdCl2 with hydrazine. Fiber mats were electrospun from homogeneous solutions of PAN-AA and PdCl2 in dimethylformamide (DMF). Pd cations were reduced to Pd metals when fiber mats were treated in an aqueous hydrazine solution at room temperature. Pd atoms nucleate and form small crystallites whose sizes were estimated from the peak broadening of X-ray diffraction peaks. Two to four crystallites adhere together and form agglomerates. Agglomerate sizes and fiber diameters were determined by scanning and transmission electron microscopy. Spherical Pd nanoparticles were dispersed homogeneously on the electrospun nanofibers. The effects of copolymer composition and amount of PdCl2 on particle size were investigated. Pd particle size mainly depends on the amount of acrylic acid functional groups and PdCl2 concentration in the spinning solution. Increasing acrylic acid concentration on polymer chains leads to larger Pd nanoparticles. In addition, Pd particle size becomes larger with increasing PdCl2 concentration in the spinning solution. Hence, it is possible to tune the number density and the size of metal nanoparticles. The catalytic activity of the Pd nanoparticles in electrospun mats was determined by selective hydrogenation of dehydrolinalool (3,7-dimethyloct-6- ene-1-yne-3-ol, DHL) in toluene at 90 °C. Electrospun fibers with Pd particles have 4.5 times higher catalytic activity than the current Pd/Al2O3 catalyst
Spectroscopy of 32Ne and the Island of Inversion
We report on the first spectroscopic study of the N=22 nucleus 32Ne at the
newly completed RIKEN Radioactive Ion Beam Factory. A single gamma-ray line
with an energy of 722(9) keV was observed in both inelastic scattering of a 226
MeV/u 32Ne beam on a Carbon target and proton removal from 33Na at 245 MeV/u.
This transition is assigned to the de-excitation of the first J^pi = 2+ state
in 32Ne to the 0+ ground state. Interpreted through comparison with
state-of-the-art shell model calculations, the low excitation energy
demonstrates that the Island of Inversion extends to at least N=22 for the Ne
isotopes.Comment: Accepted for publication in Phys. Rev. Lett. 11 pages, 3 figure
Early phase observations of extremely luminous Type Ia Supernova 2009dc
We present early phase observations in optical and near-infrared wavelengths
for the extremely luminous Type Ia supernova (SN Ia) 2009dc. The decline rate
of the light curve is , which is one of the
slowest among SNe Ia. The peak -band absolute magnitude is mag even if the host extinction is mag. It reaches
mag for the host extinction of mag as
inferred from the observed Na {\sc i} D line absorption in the host. Our
-band photometry shows that the SN is one of the most luminous SNe Ia
also in near-infrared wavelengths. These results indicate that SN 2009dc
belongs to the most luminous class of SNe Ia, like SN 2003fg and SN 2006gz. We
estimate the ejected Ni mass of \Msun for no host
extinction case (or 1.6 0.4 M for the host extinction of
mag). The C {\sc ii} 6580 absorption line keeps visible
until a week after maximum, which diminished in SN 2006gz before its maximum
brightness. The line velocity of Si {\sc ii} 6355 is about 8000 km
s around the maximum, being considerably slower than that of SN 2006gz,
while comparable to that of SN 2003fg. The velocity of the C {\sc ii} line is
almost comparable to that of the Si {\sc ii}. The presence of the carbon line
suggests that thick unburned C+O layers remain after the explosion. SN 2009dc
is a plausible candidate of the super-Chandrasekhar mass SNe Ia
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