127 research outputs found
Utility of Sea Surface Height anomaly (SSHa)in determination of Potential Fishing Zones
Physical processes in the oceans can be monitored by altimeters well before a radiometer can in terms of temperature or chlorophyll concentration. Herein we show the importance of Sea Surface Height anomaly (SSHa, retrieved with altimeter) in demarcating potential fishing
zones. We also show how SSHa can help predict tuna movements, horizontally as well as vertically in the water column. Moreover, we prove these prediction with positively
correlating SSHa to tuna hooking rates. In the end, we list out present and potential future sources from where SSHa can be retrieved in order to provide improved fishery advisories
A prospective study of efficacy of ultrasound guided transversus abdominis plane block for postcesarean analgesia
Background: The ultrasound guided transversus abdominis plane (TAP) block which provides effective analgesia after lower abdominal surgeries including caesarean section. It is a simple and reliable technique. In this prospective, randomized double-blind study, we determined the efficacy of TAP block using 0.25% Bupivacaine and 0.9N Saline with respect to VAS for pain, postoperative Tramadol consumption and post-operative ondansetron usage.Methods: This study was conducted on 100 adult patients of ASA physical status I and II in the age group of 18 to 40 years undergoing elective lower segment cesarean section under spinal anaesthesia. Study group received TAP block with 0.25% Bupivacaine and control group received 10 ml of 0.9N saline on each side. Patients were analyzed for postoperative pain by pain score (at rest, on movement, on cough) using VAS was recorded at 0, ½, 1, 2, 4, 6, 12 and 24 hours postoperatively. Need for rescue analgesia was assessed by time to first dose of Tramadol requirement and total dose of Tramadol over 24 hours of postoperative period. Ondansetron (4 mg i.v.) was administered whenever nausea score was more than 2 or the patient vomited. All the data was noted using uniform performs.Results: Patients received TAP block with 0.25% Bupivacaine had better pain scores at first hour of postoperative period during rest, cough and movement which was statistically significant (p0.001).Conclusions: TAP block using ultrasound provides substantial reduction in Tramadol consumption, time to first dose of rescue tramadol when compared with control group. This study reinforces the recommendation for TAP as a part of multimodal post-operative analgesic regimen
Laxative Property of Safoof-E-Sana, a Unani Formulation
An investigation was carried out to study the laxative property of aqueous extract Safoof-ESana in the unani formulation. Aqueous extract of Safoof-E-Sana was evaluated for laxative property and was measured by weighing the fecal out at 8th and 16th hour of drug administration. Safoof-E-Sana at 50, and 100 mg/kg showed dose dependent laxative effect. The results are compared with standard Senna. Safoof-E-Sana was showed significant laxative activity
Automated Identification of Oceanic Fronts for Operational Generation of Potential Fishing Zone (PFZ) Advisories
PFZs, are essentially the frontal structures as identified from the satellite images of Sea Surface Temperature (SST) and chlorophyll concentration. These regions are known for fish aggregation and provide cost-effectiveness in offshore fishing operations. Subjective
identification of fronts may lead to human-errors, non-negotiable beyond a limit. To overcome this, we propose utilization of tools that help automated identification of the frontal structures. This approach not only removes the errors, but also helps shorten the time period of the operational process-chai
Formulation and evaluation of herbal face cream with green tea extract
Face cream is a semi-solid preparation for improving skin colour. The purposes of the present research work was to formulate and evaluate herbal face cream with green tea extract, turmeric, aloe vera gel as a skin toner. Herbal creams offer several advantages over synthetic creams. The majority of existing creams which has prepared from drugs of synthetic origin and gives extras fairness to face, but it has several side effects such as itching or several allergic reactions. Herbal creams do not have any of these side effects, without side effects it gives the nourishment to skin. Method carried out to prepare herbal cream was vanishing cream formulation. Firstly, oil phase was prepared, Secondly aqueous phase was prepared. Then aqueous phase was added into the oil phase at 700 c with continuous stirring. Now, once the transfer was completed it was allowed to come at room temperature all the while being stirred. Perfume was added at last just before the finished product was transferred to suitable container. The above prepared herbal cream was evaluated with parameters such as pH, homogeneity by visual and by touch, appearance (colour), rub out (spread ability, wetness), washability, consistency and emolliency. The study suggests that the composition of extract and the base of the cream F1 are more stable and safe
Stability and Effective Process Control for Secure Email Filtering
A fantastic tool for both commercial and personal communication is electronic mail. It has increasingly become a necessary component of our working life since it is straightforward, available, and simple to use. Spam emails have started to tarnish internet experiences and threaten the integrity of email. Due to the exponential growth of spam, both people and organisations are under a great deal of financial and other strain. In order to prevent the future of email itself from being in jeopardy, a solution to the spam problem must be discovered. There is an urgent need to solve the Email spam issue since spam volume has been rising over the last several decades. As part of this effort, many effects of spam emails on businesses and people were noted and thoroughly examined. In order to properly assess current technologies, solutions, and methods, a comprehensive literature review was conducted throughout the procedures. The goals of this work is to develop new methodologies for the implementation of new strategies for the efficient management of email spam and to construct a proof-of-concept software system for the Process controlled assessment of such strategies
Following tagged Yellowfin tuna along the east coast of India explains its feeding behavior: a case study in the Bay of Bengal
Horizontal movement of pelagic fish predator, Yellowfin (Thunnus albacares) tuna, in the oceanic waters of Bay of Bengal has been decoded. Pop-up Satellite Archival Tags (PSATs) were attached to adult tunas to study their distribution and migration. For this, environmental satellite data were matched with the tag locations to understand and characterize habitats of this species. A sub-set of the tag data was selected corresponding to the maximum resident time of tuna indicated by a high density data points. The tagged tuna spent 60 to 70% of its time in the waters having surface temperature within 28o to 29.5oC and sea surface height anomaly within+5 to +12 cm. The tag positions were located on the satellite images; chlorophyll, sea surface temperature, zooplankton and sea surface height anomaly. The two conditions, specific range of temperature and prey abundance, were found necessary for aggregation of tuna
Biochemical & Hematological parameters to predict severity and mortality in COVID 19 patients – a retrospective study
Introduction: Coronavirus diseases (COVID-19), the global pandemic has posed a serious threat to the health of individuals across the world and is associated with increased morbidity and mortality. Several biochemical and hematological parameters are found to be altered in these patients and there is a need to identify a suitable biomarker that can help in better risk stratification of these patients. Hence in this study, we intend to evaluate the clinical utility of these parameters to predict severity and mortality in COVID-19 patients.
Material & Methods: A retrospective, observational study was conducted in a tertiary care hospital involving Reverse Transcription Polymerase Chain Reaction (RT-PCR) positive COVID-19 patients (n-322). Data about patient\u27s age, gender, co-morbidities, duration of hospital and intensive care unit (ICU) stay, need for mechanical ventilation and laboratory investigations were obtained from the Hospital Information System (HIS).
Results: The average duration of hospital stay was 10 days, and the ICU stay of these patients was 6.5 days.[M1] [DSS2] There was a statistically significant increase in C-reactive protein (CRP), ferritin, lactate dehydrogenase (LDH), aspartate aminotransferase (AST), neutrophils, and neutrophil/lymphocyte ratio (NLR), and lower mean lymphocytic count (p=0.05), in patients who required ICU admission when compared to those who didn’t and[M3] [DSS4] also among non-survivors compared to survivors.
Conclusion: Among the various biochemical & hematological markers, CRP, ferritin, LDH AST, and NLR were found to be better predictors of severity and mortality in COVID 19 patients. Timely monitoring of these markers would therefore help in better management and improved outcome for these patients
Simultaneous expression of regulatory genes associated with specific drought‐adaptive traits improves drought adaptation in peanut
Adaptation of crops to drought-prone rain-fed conditions can be achieved by improving plant traits such as efficient water mining (by superior root characters) and cellular-level tolerance mechanisms. Pyramiding these drought-adaptive traits by simultaneous expression of genes regulating drought-adaptive mechanisms has phenomenal relevance in improving stress tolerance. In this study, we provide evidence that peanut transgenic plants expressing Alfalfa zinc finger 1 (Alfin1), a root growth-associated transcription factor gene, Pennisetum glaucum heat-shock factor (PgHSF4) and Pea DNA helicase (PDH45) involved in protein turnover and protection showed improved tolerance, higher growth and productivity under drought stress conditions. Stable integration of all the transgenes was noticed in transgenic lines. The transgenic lines showed higher root growth, cooler crop canopy air temperature difference (less CCATD) and higher relative water content (RWC) under drought stress. Low proline levels in transgenic lines substantiate the maintenance of higher water status. The survival and recovery of transgenic lines was significantly higher under gradual moisture stress conditions with higher biomass. Transgenic lines also showed significant tolerance to ethrel-induced senescence and methyl viologen-induced oxidative stress. Several stress-responsive genes such as heat-shock proteins (HSPs), RING box protein-1 (RBX1), Aldose reductase, late embryogenesis abundant-5 (LEA5) and proline-rich protein-2 (PRP2), a gene involved in root growth, showed enhanced expression under stress in transgenic lines. Thus, the simultaneous expression of regulatory genes contributing for drought-adaptive traits can improve crop adaptation and productivity under water-limited conditions
Utjecaj superdezintegratora na oslobađanje efavirenca iz tableta
Efavirenz (EFV) tablets of different doses were prepared by a wet granulation process using different superdisintegrants such as crosscarmellose sodium (CCS), sodium starch glycollate (SSG) and crosspovidone (CP) to evaluate the role of different disintegrants on the in vitro release of EFV. Further, the mode of addition of disintegrants on EFV dissolution from tablets containing 600 mg of the drug was evaluated by incorporating the disintegrant extragranularly (EG), intragranularly (IG) or distributing them equally (IG and EG). In vitro dissolution of the prepared tablets was conducted using the recommended medium and a dissolution medium developed in-house, which had the propensity to discriminate between the formulations.
The t50 and t80 values were indicative of the fact that drug release was faster from tablet formulations containing CP. CP was able to release the drug faster than the other two disintegrants in both dissolution media and the drug release was unaffected by the mode of CP addition.U radu je opisana priprava tableta s različitim dozama efavirenca (EFV) metodom vlažne granulacije. Za tabletiranje korišteni su različiti superdezintegratori, poput natrijeve kroskarameloze (CCS), natrijeva škrobnog glikolata (SSG) i krospovidona (CP), kako bi se procijenio utjecaj vrste i načina dodavanja dezintegratora na oslobađanje EFV in vitro. U tu svrhu pripravljene su tablete sa 600 mg EFV, a dezintegrator je dodavan ekstragranularno (EG), intragranularno (IG) ili je bio podjednako raspršen (IG i EG). In vitro oslobađanje praćeno je u preporučenom mediju i mediju izrađenom u našem laboratoriju kako bi se uočila razlika između formulacija. Vrijednosti t50 i t80 ukazuju na to da je oslobađanje lijeka brže iz formulacija koje sadrže CP u oba medija. Način dodavanja CP nema utjecaj na oslobađanje lijeka, osim za CCS, gdje se ekstragranularno dodavanje pokazalo povoljnijim
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