GalPak3D: A Bayesian parametric tool for extracting morpho-kinematics of galaxies from 3D data

We present a method to constrain galaxy parameters directly from three-dimensional data cubes. The algorithm compares directly the data with a parametric model mapped in $x,y,\lambda$ coordinates. It uses the spectral lines-spread function (LSF) and the spatial point-spread function (PSF) to generate a three-dimensional kernel whose characteristics are instrument specific or user generated. The algorithm returns the intrinsic modeled properties along with both an `intrinsic' model data cube and the modeled galaxy convolved with the 3D-kernel. The algorithm uses a Markov Chain Monte Carlo (MCMC) approach with a nontraditional proposal distribution in order to efficiently probe the parameter space. We demonstrate the robustness of the algorithm using 1728 mock galaxies and galaxies generated from hydrodynamical simulations in various seeing conditions from 0.6" to 1.2". We find that the algorithm can recover the morphological parameters (inclination, position angle) to within 10% and the kinematic parameters (maximum rotation velocity) to within 20%, irrespectively of the PSF in seeing (up to 1.2") provided that the maximum signal-to-noise ratio (SNR) is greater than $\sim3$ pixel$^{-1}$ and that the ratio of the galaxy half-light radius to seeing radius is greater than about 1.5. One can use such an algorithm to constrain simultaneously the kinematics and morphological parameters of (nonmerging) galaxies observed in nonoptimal seeing conditions. The algorithm can also be used on adaptive-optics (AO) data or on high-quality, high-SNR data to look for nonaxisymmetric structures in the residuals.Comment: 16 pages, 10 figures, accepted to publication in AJ, revised version after proofs corrections. Algorithm available at http://galpak.irap.omp.e

Signatures of Cool Gas Fueling a Star-Forming Galaxy at Redshift 2.3

Galaxies are thought to be fed by the continuous accretion of intergalactic gas, but direct observational evidence has been elusive. The accreted gas is expected to orbit about the galaxy's halo, delivering not just fuel for star-formation but also angular momentum to the galaxy, leading to distinct kinematic signatures. Here we report observations showing these distinct signatures near a typical distant star-forming galaxy where the gas is detected using a background quasar passing 26 kpc from the host. Our observations indicate that gas accretion plays a major role in galaxy growth since the estimated accretion rate is comparable to the star-formation rate.Comment: 33 pages, 8 figures, version matching the proofed tex

Nanoparticle–membrane interactions

Engineered nanomaterials have a wide range of applications and as a result, are increasingly present in the environment. While they offer new technological opportunities, there is also the potential for adverse impact, in particular through possible toxicity. In this review, we discuss the current state of the art in the experimental characterisation of nanoparticle-membrane interactions relevant to the prediction of toxicity arising from disruption of biological systems. One key point of discussion is the urgent need for more quantitative studies of nano-bio interactions in experimental models of lipid system that mimic in vivo membranes

A study on the multicolour evolution of Red Sequence galaxy populations: insights from hydrodynamical simulations and semi-analytical models

By means of our own cosmological-hydrodynamical simulation and semi-analytical model we studied galaxy population properties in clusters and groups, spanning over 10 different bands from UV to NIR, and their evolution since redshift z=2. We compare our results in terms of galaxy red/blue fractions and luminous-to-faint ratio (LFR) on the Red Sequence (RS) with recent observational data reaching beyond z=1.5. Different selection criteria were tested in order to retrieve galaxies belonging to the RS: either by their quiescence degree measured from their specific SFR ("Dead Sequence"), or by their position in a colour-colour plane which is also a function of sSFR. In both cases, the colour cut and the limiting magnitude threshold were let evolving with redshift, in order to follow the natural shift of the characteristic luminosity in the LF. We find that the Butcher-Oemler effect is wavelength-dependent, with the fraction of blue galaxies increasing steeper in optical colours than in NIR. Besides, only when applying a lower limit in terms of fixed absolute magnitude, a steep BO effect can be reproduced, while the blue fraction results less evolving when selecting samples by stellar mass or an evolving magnitude limit. We then find that also the RS-LFR behaviour, highly debated in the literature, is strongly dependent on the galaxy selection function: in particular its very mild evolution recovered when measured in terms of stellar mass, is in agreement with values reported for some of the highest redshift confirmed (proto)clusters. As to differences through environments, we find that normal groups and (to a lesser extent) cluster outskirts present the highest values of both star forming fraction and LFR at low z, while fossil groups and cluster cores the lowest: this separation among groups begins after z~0.5, while earlier all group star forming properties are undistinguishable.Comment: revised version, A&A accepted (11 pages, 6 figures

The Relation Between Activity and Environment in Compact Groups of Galaxies

We present the results of the classification of spectral activity types for 193 galaxies from a new sample of 49 compact groups of galaxies in the southern hemisphere (SCGs). This sample was selected in automated fashion from a digitized galaxy catalogue, covering an area of ~5200 sq deg, around the South Galactic Pole. It is complete up to m ~14.5 in b_j for the brightest galaxy of the group. The spectral analysis of the SCG galaxies confirms the results previously obtained for a smaller sample of Hickson's compact groups (HCG). We confirm the luminosity-activity and morphology-activity relations, as well as the predominance of AGNs (41% of SCGs galaxies). We verified also that the number of early-type non-emission-line galaxies increases with the number of members in the group. The SCGs contain more star-forming galaxies (SFGs) and less non-emission-line galaxies than HCGs, which suggests that they probe a wider range of physical properties. The SFGs are composed in majority of HII Nucleus Galaxies, which have less intense star formation than starburst galaxies. The star formation activity in SCGs is, consequently, remarkably low. The SFGs show also evidence for nuclear activity. If these results are further confirmed, 70% of the galaxies in SCGs would then have an active nucleus, making these systems remarkably rich in AGNs. Curiously, however, this characteristic of CGs generally excludes Seyfert 1 galaxies.(Abridged)Comment: 53 pages, Latex, 9 encapsulated postscript figures, Accepted for publication in The Astronomical Journa

Identification of the first enantiopure Rac1–Tiam1 protein–protein interaction inhibitor and its optimized synthesis via phosphine free remote group directed hydroarylation

A phospine free hydroarylation reaction applied to norbornene derivatives is described for the first time and was exploited for the regioselective gram scale synthesis of AR-148, a known Rac1\u2013Tiam1 PPI inhibitor. Umpolung conversion of the nitro group into free amine allowed the regiocontrol of the key arylation step via a long range effect. The effect of AR-148 in comparison with its enantiomers on Rac1 activation of has been evaluated and ( 12)AR-148 has been identified as the first enantiomerically pure inhibitor of Rac1\u2013Tiam1 PPI

Time-gated transillumination and reflection by biological tissues and tissuelike phantoms: simulation versus experiment

A numerical method is presented to solve exactly the time-dependent diffusion equation that describes light transport in turbid media. The simulation takes into account spatial variations of the scattering and absorption factors of the medium and the objects as well as random fluctuations of these quantities. The technique is employed to explore the possibility of locating millimeter-sized objects immersed in turbid media from time-gated measurements of the transmitted or reflected (near-infrared) light. The simulation results for tissue-like phantoms are compared with experimental transillumination data, and excellent agreement is found. Simulations of time-gated reflection experiments indicate that it may be possible to detect objects of 1-mm radius.

The Midwifery Traditional Methods

\u201cMidwifery traditional method\u201d is the only one which supports clinical certainty and that can introduce to a hands on care. Kind Editor, we think it is fundamental help obstetricians and midwives to develop competencies for birth and encourage to make use of the precious cultural baggage which is the obstetric semeiotic