69 research outputs found

    1980 sonrası Türkiye'de sermaye birikiminin gelişimi

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    TEZ3167Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 1998.Kaynakça (s. 64-67) var.vi, 67 s. ; 30 cm.

    Hastane personeli ile sağlıklı bireylerde burun kültürlerinden ve subklaviyen kateterlerden elde edilen stafilokokların beta-laktamaz, slime yapma özellikleri ve antibiyotik duyarlılıklarının araştırılması

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    Yakın zamanlara kadar vücutta kommensal olduğu sanılan KNS'ların son zamanlarda yapılan çalışmalarda extrasellüler bir slime maddesi meydana getirerek, vücuda implante edilen yabancı yüzeylere (intravenöz kateterler, vcntrikUlopcriloncal santiar, pcys-meykır vb.) yapışarak infeksiyona yol açtıkları belirlendi. Çalışmamızda hastane personelinin burun kültürlerinden ve i.v. kaleterlerden izole etliğimiz slafilokoklarda slime maddesini araştırdık. Hastane personelinden izole ettiğimiz suşlarla, kontrol grubunun özelliklerini karşılaştırdık. Toplam 186 kişi ile yaptığımız bu çalışmada, elde ettiğimiz 160 stafilokok susunda slime maddesi ile birlikte, beta-laktamaz yapma oranlarını ve 14 adet antibiyotiğe duyarlılıklarını belirledik. Beta-laktamaz yapma oranını S. aurcus'larda % 47, KNS'larda % 43, slimc pozitifliğini de S. aurcus'larda % 23, KNS'larda % 62 olarak bulduk. 14 antibiyotik içinde vanko- misin, siprofloksasin ve sefoperazon/sul baklam en duyarlı ilk Uç antibiyotikti. Sonuçlar Chi-square testi ile değerlendirildi. Hastane personeli ve i.v. kaleterlerden elde edilen KNS'lar ile kontrol grubun dan izole edilenler arasında slime yapma oranları açısından islalistiki olarak fark anlam lı idi (p0,05). Çalışmada elde ettiğimiz sonuçlar literatür bilgileri ışığı altında tartışıldı. Sonuçların uyumluluk gösterdiği görüldü.İl has been understood thai coagulasc-ncgativc staphylococci (CNS) which have been known as commensal organisms until recently can cause infections by producing slime substance which enables them to attach to the surfaces of foreign materials (such as intravenous cateters, ventriculo-periloncal shunts, pace-makers etc). In this study, wc investigated the slime substance in staphylococcus obtained from both nasal cultures of hospital staff and intravenous cateters. In addition, we compared the species from both hospital staff and controls. Of totally 186 subjects, 160 samples were investigated in terms of slime substance, the ratio of beta-lactamase posilivincss and the sensitivity to 14 different antibiotics. Wc found the ratio of P-laclamasc production to be 47 % in S. aureus and 48 % in CNS, and the slime posilivcncss to be 25 % in S. aureus and 62 % CNS. Of 14 antibiotics, Vancomicin, Ciprofloxacin and Ccfopcrason/sulbaclam were the most sensitive ones. The result were evaluated with Chi -square test. The difference in the amount of slime produced between control and study group samples was beta-lactamase production (p0,05). Our results were discussed in the light of literature. It was found that the results were in agreement with those of literature

    Association of male pattern baldness with angiographic coronary artery disease severity and collateral development

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    Objective We aimed to investigate whether there is an association between male pattern baldness and angiographic coronary artery disease (CAD) severity and collateral development, which has not been reported previously. Methods Coronary arteriograms, CAD risk factors, lipid parameters and presence and severity of baldness in 511 male patients were prospectively evaluated. Baldness was classified into five groups. Severity of CAD was evaluated with the Gensini scoring system and collateral development with Rentrop scores. Results Although subjects with a higher Gensini score had more frequent and severe baldness, they were older than the group with lower Gensini scores. Bald patients had a higher Gensini score when compared with their non-bald counterparts. In univariate analysis, age more than 60, body mass index more than 30, smoking and baldness were predictors of high Gensini scores. In multivariate analysis, only age more than 60, body mass index more than 30 and smoking were independent predictors of a high Gensini score. There were no differences in terms of presence and severity of baldness in subjects with and without adequate collateral development. Conclusions There was no relation between presence, severity and age of occurrence of male pattern baldness and Gensini and Rentrop scores, which are important measures of presence and severity of CAD

    Evaluation of right atrial volumes and functions by real-time three-dimensional echocardiography in patients after acute inferior myocardial infarction

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    Background Methods Right ventricle (RV) involvement causes acute systolic and diastolic functional alterations in the RV in patients after inferior myocardial infarction (IMI), which may result in an increase in left ventricle (LV) end-diastolic and right atrial (RA) pressure. In our study, we sought to evaluate RA volumes and mechanical functions using real-time three-dimensional echocardiography (RT3DE) in IMI patients with or without RV involvement. Ninety-six consecutive patients with IMI (mean age: 59.7 +/- 10.2 years, 60 female) were included. RV myocardial involvement (RVMI) was defined as the presence of a culprit lesion at the proximal portion of the first RV marginal branch in coronary angiography. The study population was divided into two groups: IMI (58.3%) and IMI + RVMI (41.7%). Patients were evaluated using conventional two-dimensional echocardiography (2DE) and RT3DE. Results Conclusions In RT3DE measurements, IMI + RVMI patients had significantly higher RA phasic volumes and worse conduit mechanical function. A receiver operating characteristic (ROC) curve analysis revealed that an RT3DE RA maximum volume (Vmax) index > 27.9 mL/m(2) was an independent predictor of RV involvement in patients after acute IMI, with a sensitivity of 80.0% and a specificity of 89.3%. Right ventricle involvement may cause an increase in RA phasic volumes and deterioration of conduit function in patients with acute IMI

    Early Detection of Bi-ventricular and Atrial Mechanical Dysfunction Using Two-Dimensional Speckle Tracking Echocardiography in Patients with Sarcoidosis

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    Purpose Sarcoidosis is a systemic inflammatory disease with unknown etiology involving several organs. Myocardial involvement, pericarditis, severe rhythm abnormalities, and heart valve disease due to papillary muscle dysfunction are some of the cardiac manifestations. Conventional echocardiographic methods remain insufficient for the determination of subclinical myocardial dysfunction in patients with sarcoidosis. In our study, we investigated the impact of sarcoidosis on bi-ventricular and atrial functions using two-dimensional (2D) speckle tracking echocardiography (STE). Methods Forty patients with sarcoidosis and 20 age and sex-matched controls were recruited into study. All subjects underwent a transthoracic echocardiography for the evaluation of ventricular and atrial functions with 2D STE. Results Left ventricular (LV) dimensions, LV ejection fraction, and right ventricular (RV) systolic velocity were similar between the two groups. Left atrial (LA) diameter was significantly higher in sarcoidosis patients than controls. Eighteen (45 %) patients in the sarcoidosis group and 1 (5 %) patient in the control group had LV diastolic dysfunction. LV global longitudinal, radial, circumferential strain, twist, untwists, and RV global longitudinal strain values were significantly lower in sarcoidosis patients compared to controls. LA and RA reservoir functions were also significantly lower in sarcoidosis patients than controls. Conclusion Although impaired LV diastolic function was detected using conventional parameters, only novel advanced echocardiographic modalities demonstrated impaired bi-ventricular and atrial mechanical functions in patients with sarcoidosis

    A Patient with the Diagnosis of Ulcerative Colitis Presenting with Entamoeba histolytica and Strongyloides stercoralis Infection

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    Parasitic infections may be seen in ulcerative colitis patients. Strongyloides stercoralis is a nematode which causes opportunistic infection involving the small bowel. The stool of a patient diagnosed and treated as ulcerative colitis for the last four years was examined and trophozoite forms of E. histolytica were determined. Metronidazole and diloxanide furoate were prescribed and four months after he had been discharged from the hospital, ulcerative colitis relapsed. Stool examination was repeated and E. histolytica cyst and trophozoite forms were seen. This time secnidazole and tetracycline were given. During this therapy, cyst forms of E. histolytica and rabditiform larvae of S. stercoralis were seen in control fecal examination. Albendazole was added to the treatment for three days. In the microscopic examination of the stool which was repeated two months later, no parasite forms were detected. In literature, there were no articles reporting ulcerative colitis associated with amebiosis and strongyloidosis. These results suggest that parasitologic examination of stool is very important for the diagnosis and treatment of ulcerative colitis cases resistant to therapy
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