Effects of potassium and humic acid on emergence, growth and nutrient contents of okra (Abelmoschus esculentus L.) seedling under saline soil conditions

The effects of potassium and humic acid (HA) on emergence, growth and nutrient contents of okra (Abelmoschus esculentus L cv. Sultani) seedlings in saline soil conditions were evaluated. Different levels of humic acid (0, 500, 1000 and 1500 mg kg-1-1) were applied on growing media treated with 50 mg NaCl kg-1 before seed sowing. The experiment was designed as randomized completely factorial block and each parcel had ten pots without drainage. Two okra seeds were sown in each pot having 300 cc volumes of growth media. The seedlings were thinned to one after emergence. The seedlings were irrigated with distilled water. Seed emergence, root and shoot size, leaf number, shoot and root dry weights of the plant seedlings were determined. Macro and micro nutrient (N, P, K, Ca, Mg, S, Cu, Fe, Mn and Zn) contents of seedlings were also determined. All data were subjected to a one-way analysis of variance and separated by Duncan’s multiple range test which was performed using the Costat statistical software. There were statistical differences in terms of effects of potassium and HA on the okra seedling performances. The effects of K, Ca, Na, Cu, Fe, Mn, Zn and HA applications on plant mineral (N, P, K, Ca, Cu, Fe, and Mn) contents were significant at p < 0.005.Keywords: Okra (Abelmoschus esculentus L.), potassium, humic acid, nutrient content, seedling growthAfrican Journal of Biotechnology Vol. 9(33), pp. 5343-5346, 16 August, 201

Učinci 4-vinilcikloheksen diepoksida na testise pasa

This study was aimed at investigating the effects of 4-vinylcyclohexene diepoxide (VCD) on testicular tissue in dogs. For this purpose, 30 mongrel male dogs were used and allocated to 5 groups randomly. The first group (n = 6), used as the control, was administered sesame oil by the intraperitoneal route (i/p). The VCD was administered i/p at doses of 80, 160, 240, 320 mg/kg to the second, third, fourth and the fifth groups (n = 6), respectively, once a day for 8 days. The dogs were surgically castrated on the day after the last VCD injection. The testes were removed immediately and fixed in 10% bouine solution. The testes were subjected to routine tissue processing and examined to determine the testicular damage in each testis. When compared to the control group, it was seen that the seminiferous tubule damage increased significantly in the treatment groups. Malondialdehyde levels reached the highest level in the fifth group, while superoxide dismutase, catalase, glutathione peroxidase activity and glutathione levels were higher in the control group (P0.05). Our results showed that VCD may contribute to the sterilization of male dogs.Cilj ovoga istraživanja bio je ispitati učinak 4-vinilcikloheksen diepoksida (VCD) na tkivo testisa u pasa. U tu je svrhu 30 mužjaka, križanaca, slučajnim odabirom podijeljeno u pet skupina. Prvoj, kontrolnoj skupini (n = 6) dan je VCD sa sezamovim uljem intraperitonealno. Druga skupina primila je VCD intraperitonealno u dozi od 80 mg/kg, treća 160 mg/kg, četvrta 240 mg/kg i peta skupina 320 mg/kg (n = 6), jedanput dnevno tijekom 8 dana. Psi su kastrirani dan nakon posljednje injekcije VCD-a. Testisi su odmah uklonjeni i stavljeni u 10 %-tni Bouineov fiksativ. Podvrgnuti su rutinskoj obradi tkiva te ispitani da se utvrde oštećenja na svakom testisu. U usporedbi s kontrolnom skupinom uočeno je da je u pokusnoj skupini oštećenje sjemenovoda značajno veće. Razine malondialdehida najveće su vrijednosti dosegnule u petoj skupini, dok je aktivnost superoksidne dismutaze, katalaze i glutation-peroksidaze bila veća u kontrolnoj skupini (P0,05). Rezultati pokazuju da VCD može pridonijeti sterilitetu kod muških pasa

Sosyal Sermayenin Yenilikçi Davranışa Etkisinde Girişimcilik Eğiliminin Aracılık Rolü: Gaziantep’teki Suriyeli Girişimciler Üzerine Bir Araştırma

Günümüzde bilim ve teknolojinin hızlı gelişimi ve küreselleşmeye yönelik eğilimlerle birlikte, neredeyse tüm örgütler muazzam riskler ve rekabet baskıları getiren dinamik bir iş ortamıyla karşı karşıya kalmaktadır. Yenilikçi davranış, örgütlerin uzun vadede hayatta kalması ve sürdürülebilir bir rekabet avantajı elde etmesi için benzersiz bir varlık olarak kabul edilmektedir. Öte yandan, çok sayıda bilim adamı sosyal sermaye ve girişimciliğin yenilikçi davranış üzerindeki etkisine dikkat çekmektedir. Bu perspektiften Gaziantep’teki 404 Suriyeli girişimcinin katıldığı çalışmanın temel amacı sosyal sermayenin yenilikçi davranış üzerindeki etkisini ve bu etki düzeyinde girişimcilik eğiliminin aracılık rolü olup olmadığını incelemektir. Kavramsal ve ampirik araştırma sonucu elde edilen bulgular sosyal sermayenin hem doğrudan hem de girişimcilik eğilimi aracılığıyla dolaylı olarak yenilikçi davranışı olumlu bir şekilde etkilediğini ve ayrıca sosyal sermayenin yenilikçi davranış üzerindeki etkisinde girişimcilik eğiliminin kısmi aracılık rolü de doğrulanmıştır. Bu sonuçlar sosyal sermayenin girişimcilik eğilimi aracılığıyla girişimcilerin işlevselliğini daha da artırarak daha fazla yeni yaratıcı fikirler ürettikleri ve uyguladıkları argümanına güçlü bir destek sağlamaktadır

Comparison of apparent diffusion coefficient values among different MRI platforms: a multicenter phantom study

PURPOSE:We aimed to compare apparent diffusion coefficient (ADC) values among magnetic resonance imaging (MRI) scanners from different vendors.MATERIALS AND METHODS:We used a custom-made phantom solution consisting of distilled water, 0.9% NaCl, 25% NaCl, and shampoo for diffusion-weighted MRI (DW-MRI) examinations. DW-MRI was performed with similar sequence parameters using six different 1.5 Tesla MR scanners (scanners A–F). ADC maps were automatically constructed for all DW-MR images (b factors of 0 and 1000 s/mm2). ADC measurements were performed using regions of interest and seven different software programs, including four different postprocessing workstations, two different picture archiving and communication systems, and operator console software for each MR scanner.RESULTS:The ADC values generated by scanners A and F were higher and those of scanner B were lower than those generated by the other scanners (P = 0.002). The intravendor difference in the ADC values averaged from scanners D, E, and F was statistically significant (P < 0.001). The difference between the ADC values obtained by scanners C and E was not statistically different (P = 0.15).CONCLUSION:ADC values may differ among different MRI systems used for DW-MRI. Thus, the MRI vendor should be considered when using DW-MRI in a clinical setting

EFFECTS OF DIFFERENT RESUSCITATION FLUIDS ON NO-REFLOW PHENOMENON AFTER THE HEMORRHAGIC SHOCK

Amaç: Hemorajik şok, dolaşımdaki kan volümünün azalması ile meydana gelir.Vücuttaki tüm organlarda doku hipoperfüzyonuna ve hipoksisine sebep olur. Uzamışiskemi sonrası organların kan dolaşımında en önemli fonksiyon bozukluğu,reperfüzyon başladığında kapiller kan akımındaki azalmadır ve kapiller no-reflow olarakadlandırılır.Hemorajik şokta amaç sadece zamanında hacmi yerine koymak değil, organlardakiiskemi reperfüzyon (İ/R) sonrası no-reflow fenomenini engellemeye yönelik olmalıdır.Reperfüzyon amacıyla kullanılan sıvıların organlarda no-reflow fenomenini engellemeyeyönelik etkinliklerini belirlemek amacıyla çalışma planlanmıştır.Yöntem: Bu çalışmada hemorajik şok oluşturulan ratlara (ortalama arteriyel basıncı40 mmHg\'ye azalıncaya kadar kontrollü kanatılarak) 60 dk sonra grup 2 (n=5) de %0,9 NaCl sıvısı, grup 3 (n=5) de jelatin sıvısı, grup 4 (n=5) de hidroksi etil nişasta(hydroxyethyl starch, 130 kD) sıvısı ve grup 5 (n=5) de dekstran 40 sıvısı ileresüsitasyon yapıldı. Grup 1 (n=3) kontrol grubu olarak kullanıldı ve tüm gruplarınçeşitli organlarında (karaciğer, akciğer, böbrek, beyin, bağırsak ve kalp) resüsitasyondan60 dakika sonra çini mürekkebi ile perfüze olan kapiller sayıları histopatolojikinceleme ile belirlendi.Bulgular: Kalp, akciğer, karaciğer, bağırsak ve beyin dokularında HES 130 kD vedekstran 40 resüsitasyonunda perfüze olan kapiller sayısının, %0,9 NaCl ve jelatinresüsitasyonuna göre istatiksel olarak anlamlı fazla olduğu saptandı.Sonuç: Çini mürekkebi perfüzyon yöntemi kullanarak hemorajik şokta İ/R sonrasıno-reflow fenomenini, kalp, akciğer, karaciğer, bağırsak ve beyin dokularında jelatin ve%0,9 NaCl sıvısının engellemediği, HES 130 kD\'nin ve dekstran 40 sıvılarının ise noreflowfenomenini engellediği saptandı.Objective: Hemorrhagic shock is caused by a decrease in the circulating bloodvolume. It causes hypoperfusion and hypoxia of the tissues in all organs of the body.The principal functional impairment in circulation of these organs is reduction ofcapillary blood flow at establishment of reperfusion and it is called the "no-reflowphenomenon".The objective of treatment in hemorrhagic shock should not solely be institution ofvolume on time but to prevent no-reflow phenomenon after ischemia-reperfusion(I/R) of the organs. This study was planned to investigate the efficiency of several Method: In this study, rats were resuscitated with saline in group 2 (n=5), gelatinesolution in group 3 (n=5), hydroxyethyl starch, 130 kD (HES 130 kD) in group 4(n=5) and dextran 40 in group 5 (n=5) after formation of hemorrhagic shock(controlled bleeding till a mean arterial pressure of 40 mm Hg is reached). Group 1(n=3) constituted the control group. The number of ink perfused capillaries werecounted hystopathologically in the organs (liver, lungs, kidney, brain, colon andheart) in all groups 60 minutes following resuscitationin. Indian drawing ink wasused for this purpose.Results: In comparison with the saline and gelatine groups, capillary perfusion in theheart, lung, liver, colon and brain tissues were found to be significantly improved inHES 130 kD and dextran 40 groups.Conclusions: It was concluded that using the ink perfusion method, the no-reflowphenomenon was not prevented with saline and gelatine resuscitation in the heart,lung, liver, colon and brain tissues following IR in hemorrhagic shock, while noreflowphenomenon was prevented with HES 130 kD and dextran 40 resuscitation

Crizotinib efficacy and safety in patients with advanced NSCLC harboring MET alterations: A real-life data of Turkish Oncology Group

Crizotinib is a multikinase inhibitor, effective in non-small cell lung cancer (NSCLC) harboring mesenchymal-epidermal transition (MET) alterations. Although small prospective studies showed efficacy and safety of crizotinib in NSCLC with MET alterations, there is limited real-life data. Aim of this study is to investigate real-life efficacy and safety of crizotinib in patients with advanced NSCLC harboring MET alterations. This was a retrospective, multicenter (17 centers) study of Turkish Oncology Group. Patients' demographic, histological data, treatment, response rates, survival outcomes, and toxicity data were collected. Outcomes were presented for the study population and compared between MET alteration types. Total of 62 patients were included with a median age of 58.5 (range, 26-78). Major histological type was adenocarcinoma, and 3 patients (4.8%) had sarcomatoid component. The most common MET analyzing method was next generation sequencing (90.3%). MET amplification and mutation frequencies were 53.2% (n = 33) and 46.8% (n = 29), respectively. Overall response rate and disease control rate were 56.5% and 74.2% in whole study population, respectively. Median progression free survival (PFS) was 7.2 months (95% confidence interval [CI]: 3.8-10.5), and median overall survival (OS) was 18.7 months (95% CI: 13.7-23.7), regardless of treatment line. Median PFS was 6.1 months (95% CI: 5.6-6.4) for patients with MET amplification, whereas 14.3 months (95% CI: 6.7-21.7) for patients with MET mutation (P = .217). Median PFS was significantly longer in patients who have never smoked (P = .040), have good performance score (P < .001), and responded to the treatment (P < .001). OS was significantly longer in patients with MET mutation (25.6 months, 95% CI: 15.9-35.3) compared to the patients with MET amplification (11.0 months; 95% CI: 5.2-16.8) (P = .049). In never-smokers, median OS was longer than smoker patients (25.6 months [95% CI: 11.8-39.3] vs 16.5 months [95% CI: 9.3-23.6]; P = .049). The most common adverse effects were fatigue (50%), peripheral edema (21%), nausea (29%) and diarrhea (19.4%). Grade 3 or 4 adverse effects were observed in 6.5% of the patients. This real-life data confirms efficacy and safety of crizotinib in the treatment of advanced NSCLC harboring MET alteration

Türkiye'nin Avrupa Birliği ile bütünleşme sürecinde Türk işletmelerinin karşılaştıkları yönetim sorunları ve çözümleri

TEZ3111Tez (Doktora) -- Çukurova Üniversitesi, Adana, 1998.Kaynakça (s. 189-200) var.xx, 225 s. ; 30 cm.

Domateste topraksız yetiştiricilikte değişik substrat karşımlarının ve bitki kök bölgesi ısıtmasının bitki gelişimi, verim, erkencilik ve ürün kalitesine etkileri

TEZ2016Tez (Doktora) -- Çukurova Üniversitesi, Adana, 1995.Kaynakça (s. 209-221) var.xxiii, 223 s. ; 30 cm.