Microbiota: the missing link in the etiology of inflammatory bowel disease

Within its twisted and tight walls, where a hostile and arid environment prevails, the lumen of the digestive tract nests a true microuniverse called the microbiota. The existing relationship between humans and these microorganisms is one in which both benefit, creating a condition called Eubiosis. The dynamic relationship existing between the microbiota and the human body can be affected at various times, leading to an imbalance that may have important implications on health and generating a condition called Disbiosis. Recent studies have highlighted possible links between several diseases with incompletely elucidated etiology and disturbances of the microbiota. In this review we aim to analyze the existing relationship between the imbalances of the gastrointestinal flora and the etiopathogeny inflammatory bowel diseases, a group of diseases whose incidence has increased considerably in recent years

Microbiota: the missing link in the etiology of inflammatory bowel disease

Within its twisted and tight walls, where a hostile and arid environment prevails, the lumen of the digestive tract nests a true microuniverse called the microbiota. The existing relationship between humans and these microorganisms is one in which both benefit, creating a condition called Eubiosis. The dynamic relationship existing between the microbiota and the human body can be affected at various times, leading to an imbalance that may have important implications on health and generating a condition called Disbiosis. Recent studies have highlighted possible links between several diseases with incompletely elucidated etiology and disturbances of the microbiota. In this review we aim to analyze the existing relationship between the imbalances of the gastrointestinal flora and the etiopathogeny inflammatory bowel diseases, a group of diseases whose incidence has increased considerably in recent years

Thermal Decomposition of Hafnium Ethoxide-Mollecular Precursor for Hafnia Dielectric Thin Films

The HfO2 thin-film is a very promising gate dielectric material for last generation transistors. The paper presents the thermal decomposition of hafnium ethoxide used as molecular precursor for obtaining hafnia thin films. The investigated molecular precursor is a mixture of Hf3O(OC2H5)10 and Hf4O(OC2H5)14 moisture sensitive amorphous powder. The thermal decomposition of hafnium ethoxide precursor was investigated by TG-DTG-DSC analysis from room temperature to 600 oC in nitrogen atmosphere at 5 K/min. The composition of gas products resulted during pyrolytic decomposition has been studied by Fourier Transformation Infrared Spectroscopy (FTIR) and Mass Spectroscopy (MS). In the gas products, hydrogen, methyl, ethyl, vinyl, hydroxyl groups, acetic aldehyde and acetylene were identified. From mass spectroscopy and FTIR data results that the loss of ethoxy groups from the molecular precursor occurs in the decomposition steps between 200 and 375 oC. That suggests that in different steps, ligands from different coordination spheres are lost

Study of molybdenum stable oxide film in simulated body fluid

This study's main goal is to thoroughly compare the mechanical attributes and biocompatibility of the recently created titanium alloy Ti15Mo7Zr15Ta1Si (62% Ti, 15% Mo, 7% Zr, 15% Ta, 1% Si) to that of the pure metal Mo. The samples underwent a series of meticulous preparation procedures, including chip preparation, polishing, grinding, and cutting, to enable a thorough evaluation. These preparation steps were essential for ensuring the samples' consistency and uniformity, which allowed for accurate and reliable analyses of their mechanical and corrosionrelated properties. The samples' microstructure and surface morphology were also investigated using metallographic techniques, allowing a thorough examination of any potential flaws, grain boundaries, or phase compositions. Additionally, electrochemical tests were used to investigate the materials' corrosion resistance and electrochemical characteristics in environments that mimicked physiological conditions. The samples were subjected to a variety of electrochemical analyses, such as polarization curves and impedance spectroscopy, in order for the researchers to fully comprehend the corrosion behavior of the materials and their suitability for biomedical applications

High-K Dielectric Inorganic-Organic Hybrid Thin Films for Field Effect Transistors (FETFT)

The paper discusses the challenges to develop thin films transistors for flexible transparent electronics, displays etc. The sol-gel preparation of hybrid thin films based on dielectric oxides nanoparticles (SiO2 NPs, ZrO2 NPs) and polymethy methacrylate (PMMA) is presented. The high-k hybrid thin films, evaluated as gate dielectric in a MIM structures, were deposed by spin-coating teqhnique. The multilayers (thin films) configuration of MIM structures were investigated by scanning electron microscopy (SEM) and electrical properties. The I-V and C-V curves showed a better dielectric behavior of hybrid films with respect to the simple PMMA films. Dielectric constant values of 2.1, 3.4 and 5.4 have been obtained for PMMA, ZrO2-PMMA and SiO2-PMMA films, respectively

Regenerative medicine options in treating premature ovarian failure

Infertility is generally defined as the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. premature ovarian failure (POF) is a cause of female infertility, being estimated to affect 1% of the general population. This condition represents a loss of hormonal and germinative activity of the ovaries due to a lack in the number of active follicles in women under 40 years old. Regenerative medicine represents a complex therapeutic option and it consists of technologies such as the use of stem cells, tissue engineering, and gene therapy alone or in different combinations. Although the boundaries of regenerative medicine are not clearly outlined at present, this paper is aiming to review its possibility of treatment in the future in what concerns POF, focusing more on the use of stem cell therapy. Stem cell therapy could be a feasible therapeutic approach for POF as the cells can be easily obtained. However, additional clinical studies are needed because until now the majority of the literature focuses on animal models for the evaluation of the role of stem cells on treating POF. Additionally, the platelet-rich plasma (PRP) approach for POF should be kept in mind as it was shown to be useful in the regeneration of multiple types of tissue

Significant benefits of AIP testing and clinical screening in familial isolated and young-onset pituitary tumors

Context Germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are responsible for a subset of familial isolated pituitary adenoma (FIPA) cases and sporadic pituitary neuroendocrine tumors (PitNETs). Objective To compare prospectively diagnosed AIP mutation-positive (AIPmut) PitNET patients with clinically presenting patients and to compare the clinical characteristics of AIPmut and AIPneg PitNET patients. Design 12-year prospective, observational study. Participants & Setting We studied probands and family members of FIPA kindreds and sporadic patients with disease onset ≤18 years or macroadenomas with onset ≤30 years (n = 1477). This was a collaborative study conducted at referral centers for pituitary diseases. Interventions & Outcome AIP testing and clinical screening for pituitary disease. Comparison of characteristics of prospectively diagnosed (n = 22) vs clinically presenting AIPmut PitNET patients (n = 145), and AIPmut (n = 167) vs AIPneg PitNET patients (n = 1310). Results Prospectively diagnosed AIPmut PitNET patients had smaller lesions with less suprasellar extension or cavernous sinus invasion and required fewer treatments with fewer operations and no radiotherapy compared with clinically presenting cases; there were fewer cases with active disease and hypopituitarism at last follow-up. When comparing AIPmut and AIPneg cases, AIPmut patients were more often males, younger, more often had GH excess, pituitary apoplexy, suprasellar extension, and more patients required multimodal therapy, including radiotherapy. AIPmut patients (n = 136) with GH excess were taller than AIPneg counterparts (n = 650). Conclusions Prospectively diagnosed AIPmut patients show better outcomes than clinically presenting cases, demonstrating the benefits of genetic and clinical screening. AIP-related pituitary disease has a wide spectrum ranging from aggressively growing lesions to stable or indolent disease course

Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216

The Agreement in Accuracy between Tomograms, Resistograms, and the Actual Condition of the Wood from Lime Trees Harvested from Cities

The internal quality of the wood is one of the main factors affecting the stability of trees, and it has always been of great interest to science and practice. For this reason, the present study aims to compare the results obtained by wood tomograms with those of resistance to drilling and the visual appearance after cutting a slice with a chain-saw, both to evaluate the presence and dimensions of the inside defects, and also to evaluate the irregularities of the wood structure. Round pieces of lime wood harvested from public areas were used for comparison by taking sound tomograms, followed by taking resistograms on two perpendicular directions at the same level. The results showed that internal wood defects are not always the ones that lead to reduced speeds of sound propagation through the wood. In addition, there were instances in which changes in the internal structure of the wood led to improperly colored tomograms, namely the sections characterizing the point of insertion of a thick branch in the trunk, where the tomograms indicated low speeds of sound transfer through the wood in the stem and high speeds in the wood of the branch

On the Operator Space UMD Property and Non-Commutative Martingale Inequalities

119 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002.We prove that for 1 &le; p < q < infinity the analogue of the classical result BMO,Lp pq = Lq holds in the setting of a finite von Neumann algebra M , equipped with an increasing filtration ( M n)n&ge;1 of von Neumann subalgebras. We also obtain the corresponding results for the real method of interpolation. We discuss the appropriate operator space matrix norms and show that these interpolation results hold in the category of operator spaces. We apply further interpolation techniques to the study of the operator space UMD property, introduced by Pisier in the context of non-commutative vector-valued Lp-spaces, associated to a hyperfinite (and finite) von Neumann algebra. We discuss basic stability properties of UMDp operator spaces. It is unknown whether the property is independent of p in this setting. We show that for 1 < p, q < infinity, the Schatten q-classes Sq are UMDp. We provide further examples of UMDp (independent of p) operator spaces, including the non-commutative Lorentz spaces associated to a hyperfinite (and finite) von Neumann algebra.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD