Long-Term Voyages and Bone Mass Among Seamen

東京水産大学海洋生産学専攻東京水産大学練習船海鷹丸東京水産大学練習船神鷹丸東京水産大学練習船海鷹丸東京水産大学練習船海鷹丸東京水産大学練習船神鷹丸東京水産大学練習船神鷹丸東京水産大学練習船海鷹丸東京水産大学練習船神鷹丸東京水産大学海洋生産学科東京水産大学海洋生産学

A study on health control for cadets in sea training 1. : body composition and blood circulation among cadets in sea training

東京水産大学海洋システム工学講座東京水産大学水産資源経営講座東京水産大学練習船海鷹丸東京水産大学練習船海鷹丸東京水産大学練習船海鷹丸東京水産大学練習船海鷹丸東京水産大学練習船海鷹丸東京水産大学練習船青鷹丸東京水産大学練習船青鷹丸東京水産大学名誉教

Amicrobial pustulosis associated with IgA nephropathy and Sjögren's syndrome

Amicrobial pustulosis is a rare clinical entity characterized by a relapsing pustular eruption, primarily involving the skin folds. We describe a case of amicrobial pustulosis associated with autoimmune diseases (APAD). The patient suffered from IgA nephropathy and Sjögren's syndrome. Skin symptoms were alleviated dramatically after corticosteroid pulse therapy and tonsillectomy

Evaluation of Heat Inactivation of Human Norovirus in Freshwater Clams Using Human Intestinal Enteroids

Foodborne disease attributed to the consumption of shellfish contaminated with human norovirus (HuNoV) is one of many global health concerns. Our study aimed to determine the conditions of the heat-inactivation of HuNoV in freshwater clams (Corbicula japonica) using a recently developed HuNoV cultivation system employing stem-cell derived human intestinal enteroids (HIEs). We first measured the internal temperature of the clam tissue in a water bath during boiling at 90 °C and found that approximately 2 min are required for the tissue to reach 90 °C. Next, GII.4 HuNoV was spiked into the center of the clam tissue, followed by boiling at 90 °C for 1, 2, 3, or 4 min. The infectivity of HuNoV in the clam tissue homogenates was evaluated using HIEs. We demonstrated that HuNoV in unboiled clam tissue homogenates replicated in HIEs, whereas infectivity was lost in all boiled samples, indicating that heat treatment at 90 °C for 1 min inactivates HuNoV in freshwater clams in our current HIE culture system. To our knowledge, this is the first study to determine the thermal tolerability of HuNoV in shellfish using HIEs, and our results could be informative for developing strategies to inactivate HuNoV in shellfish

Geochemical characteristics of hydrothermal fluids at Hatoma Knoll in the southern Okinawa Trough

Chemical and isotopic compositions of hydrothermal fluids from Hatoma Knoll in the southern Okinawa Trough were investigated. The hydrothermal fluids were derived from a single pure hydrothermal fluid source, but they underwent phase separation beneath the seafloor prior to venting. Only vapor-like fluids vent at the Hatoma system, and the most active area is around the center of the crater, based on the location of the maximum temperature and the lowest Cl– concentrations. Compared with other hydrothermal systems in the world, at Hatoma the pH and alkalinity, as well as the B, NH4+, K, Li, CO2, and CH4 concentrations, were higher, and the Fe and Al concentrations were lower, suggesting that the characteristics of the Hatoma hydrothermal fluids are comparable to those of the other Okinawa Trough hydrothermal fluids. Helium isotope ratios were lower than those of sediment-starved hydrothermal systems, suggesting that 4He derived from the sediment is supplied to the hydrothermal fluids in Hatoma Knoll. The carbon isotope ratios of CO2 in the hydrothermal fluids indicate an influence of organic carbon decomposition. The carbon isotope ratios of CH4 in the hydrothermal fluids imply that most of the CH4 originated from microbial methane produced in a recharge zone of the hydrothermal system. Although sediment influences are a typical feature of Okinawan Trough hydrothermal fluids, the Hatoma hydrothermal system has the lowest carbon isotope ratios of CH4 among them, which suggests that Hatoma is the most highly influenced by the sediments in the recharge zone. Thus, the degree of the sediment influences has a variable in each hydrothermal field in the Okinawa Trough

Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization

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