A large fibroma polyp of labia majora

Fibroepithelial stromal polyps are benign proliferations which are usually polypoid or pedunculated, and less than 5cm in size. They are generally single lesions but can be multiple during pregnancy. They can be polypoid or pedunculated and are usually solitary. Symptoms usually include bleeding, discharge and general discomfort with sensation of a mass. They typically have a central fibrovascular core and contain stellate and multinucleated stromal cells which are best seen beneath the surface epithelium. True myxoid stroma is absent. Although vulvovaginal fibroepithelial stromal polyps are well documented, a giant variant such as the one authors report here is rather rare. To the knowledge, present case is the largest fibroepithelial stromal polyp compared to others reported in the literature

Impact Resistance and Strength Reliability of Fiber-reinforced Concrete in Bending under Drop Weight Impact Load

This paper presents an experimental investigation on the Impact failure energy and strength reliability of fiber reinforced concrete (FRC) by using a simple drop weight test which was based on the testing procedure recommended by ACI committee 544. Two different steel fibers were used as the reinforcing material in various volume fractions such as 0%, 0.5%, 1.0% and 1.5% with a water cement ratio of 0.42. Furthermore, the two-parameter weibull distribution was used to analyze the experimental data in order to sort out a variation of test results. Using the weibull distribution, the impact failure strength reliability, in other words, the probability distribution according to which the concrete will fail, was obtained. The results indicated that the concrete containing a 1.5% volume fraction of fiber gave the best performance followed by 1.0% and 0.5% under impact loading. It was proven that the probabilistic distributions of the impact failure energy of seven types of samples approximately follow two-parameter Weibull distribution

Tensile testing of cellulose based natural fibers for structural composite applications

A series of tensile tests were conducted on a Lloyd LRX tensile testing machine for numerous natural fibers deemed potential candidates for development in composite applications. The tensile tests were conducted on the fibers jute, kenaf, flax, abaca, sisal, hemp, and coir for samples exposed to moisture conditions of (1) room temperature and humidity, (2) 65% moisture content, (3) 90% moisture content, and (4) soaked fiber. These seven fibers were then tested for the four conditions and the mechanical properties of tensile strength, tensile strain to failure, and Young's modulus were calculated for the results. These results were then compared and verified with those from the literature, with some of the fibers showing distinctly promising potential. Additionally, a study on the effect of alkalization using 3% NaOH solution was carried out on flax, kenaf, abaca, and sisal to observe impact that this common fiber pre-treatment process has on fiber mechanical properties. The result of the investigation indicated that over treatment of natural fibers using NaOH could have a negative effect on the base fiber properties. It is consequently apparent that a treatment time of less than 10 min is sufficient to remove hemicelluloses and to give the optimum effect

Modern Privacy Threats and Privacy Preservation Techniques in Data Analytics

Today we are living in a digital rich and technology driven world where extremely large amounts of data get generated every hour in the public domain, which also includes personal data. Applications like social media, e-commerce, smartphone apps, etc. collect a lot of personal data which can harm individual privacy if leaked, and hence ethical code of conduct is required to ensure data privacy. Some of the privacy threats include Digital profiling, cyberstalking, recommendation systems, etc. leading to the disclosure of sensitive data and sharing of data without the consent of the data owner. Data Privacy has gained significant importance in the recent times and it is evident from the privacy legislation passed in more than 100 countries. Firms dealing with data-sensitive applications need to abide by the privacy legislation of respective territorial regions. To overcome these privacy challenges by incorporating privacy regulations, we have designed guidelines for application development, incorporating key features of privacy regulations along with the implementation strategies which will help in developing data-sensitive applications which can offer strong and coherent privacy protection of personal data

Green Synthesis of 2-amino-3-cyano-4H-chromen-4-ylphosphonates

A facile and highly efficient and green synthetic protocol is developed for the bioactive 2-amino-3-cyano-4H-chromen-4-ylphosphonates by the one-pot reaction of various salicylaldehydes, malononitrile, and diethyl phosphite using sulfamic acid as an efficient, reusable and heterogeneous solid acid catalyst. All the synthesized compounds were characterized by their 1H-NMR, 13C-NMR, 31P-NMR, and Mass spectral studies. © 2020 Author(s).The authors are thankful to Prof. C. Devendranath Reddy, Department of Chemistry, S.V. University, Tirupati for his helpful discussions and acknowledge DST-PURSE 2nd Phase Programme in S.V. University, Tirupati funded by DST-New Delhi, India for providing instrumentation facility and funding to Mr. Gundluru Mohan through SRF (File No: 17118-UGC-III(3)/ DST-PURSE 2nd Phase/2017, Dt: 23-08-2018)

Ultrasound-Assisted PSA Catalyzed One-Pot Green Synthesis of Pyrazolyl Pyrrole Derivatives

A fast, efficient and environmentally benign synthesis of pyrazolyl pyrrole derivatives has been developed by the one-pot multicomponent reaction of an aldehyde, nitroalkane, amine, and enolizable reactant with active C-H group, using Phosphosulfonic acid (PSA) as reusable solid acid catalyst under mild, solvent-free, ultra-sonication conditions. In comparison to the existing conventional methods, this green and efficient protocol provides remarkable advantages such as good to excellent yields, lower reaction time, less cost, easy work-up and solvent-free. © 2020 Author(s).The authors are thankful to Prof. C. Devendranath Reddy, Department of Chemistry, S.V. University, Tirupati for his helpful discussions and acknowledge DST-PURSE 2nd Phase Programme in S.V. University, Tirupati funded by DST-New Delhi, India for providing instrumentation facility and funding to Mr. Gundluru Mohan through SRF (File No: 17118-UGC-III (3)/ DST-PURSE 2nd Phase/2017, Dt: 23-08-2018)

Physico-chemical and microbial analysis of water samples in Anakapalli Municipal Corporation

An investigation of microbiological and physico-chemical properties of drinking water samples from five different locations in Anakapalli municipal corporation. The water samples are subject to physico-chemical analysis by standard methods. The microbial isolation was done by a streak plate method on nutrient agar and on selective media for their identification. The final identification was done according to the Bergey’s Manual. The physico-chemical characters of all the five drinking water samples were within the recommended permissible level of WHO. The total plate count was above the WHO guideline values (<10CFU’s/ml) in the five water samples. The highest count was noticed in S5 sample (54 CFU’s/ml). The highest coliform count was observed in S3 samples (11/100 ml). Six isolates of bacteria namely: E.coli, Enterobacter aerogenes, Klebsiella pneumonia, Salmonella, Shigella, and Staphylococcus were isolated, which are highly pathogenic, the result of the study indicates that the water in Andhra University pump houses is highly contaminated and not safe for drinking and utility purposes. The study therefore, stresses on the need to control the fecal pollution of water bodies

Seasonal juvenile fishery of oilsardine (Sardinella longiceps) at Jalaripeta, Visakhapatnam

The Indian oilsardine Sardinella longiceps, locally called as ‘burra kovallu’ or ‘Kerala kovallu’ forms a juvenile fishery during October - November along the Visakhapatnam coast. This seasonal juvenile fishery is the major source of income generation for the fishermen of Jalaripeta, Visakhapatnam

Convective thundercloud development over the western ghats mountain slope in Kerala

Studies were carried out on the data from Braemore mountain observatory (lat. 8°45'N, long. 77°5'E) using a single-lens ceilometer (LIDAR), an electric field mill and a portable automatic weather station throughout the year 2010. The simultaneous data collected using the above instruments indicate the existence of strong updrafts followed by the formation of thunderclouds, a characteristic of the mountain slopes, during the thunderstorm months. Changes in atmosphere related to condensation and formation of water droplets during updraft events on the mountain slope could be detected from the ceilometer scattering data. Results of the study point to the cause of relatively more thunderstorm activity in that zone. This seems to be due to excessive updraft, which is strongly related to lightning activity in the region

Molecular Sequence of Events and Signaling Pathways in Cerebral Metastases

Brain metastases are the leading cause of morbidity and mortality among cancer patients, and are reported to occur in about 40% of cancer patients with metastatic disease in the United States of America. Primary tumor cells appear to detach from the parent tumor site, migrate, survive and pass through the blood brain barrier in order to establish cerebral metastases. This complex process involves distinct molecular and genetic mechanisms that mediate metastasis from these primary organs to the brain. Furthermore, an interaction between the invading cells and cerebral milieu is shown to promote this process as well. Here, we review the mechanisms by which primary cancer cells metastasize to the brain via a mechanism called epithelial-to-mesenchymal transition, as well as the involvement of certain microRNA and genetic aberrations implicated in cerebral metastases from the lung, breast, skin, kidney and colon. While the mechanisms governing the development of brain metastases remain a major hindrance in treatment, understanding and identification of the aforementioned molecular pathways may allow for improved management and discovery of novel therapeutic targets