774 research outputs found
Magnetic-Field Dependence of Tunnel Couplings in Carbon Nanotube Quantum Dots
By means of sequential and cotunneling spectroscopy, we study the tunnel
couplings between metallic leads and individual levels in a carbon nanotube
quantum dot. The levels are ordered in shells consisting of two doublets with
strong- and weak-tunnel couplings, leading to gate-dependent level
renormalization. By comparison to a one- and two-shell model, this is shown to
be a consequence of disorder-induced valley mixing in the nanotube. Moreover, a
parallel magnetic field is shown to reduce this mixing and thus suppress the
effects of tunnel renormalization.Comment: 5 pages, 3 figures; revised version as publishe
Interplay between one-dimensional confinement and crystallographic anisotropy in ballistic hole quantum wires
We study the Zeeman splitting in induced ballistic 1D quantum wires aligned
along the [233] and [011] axes of a high mobility (311)A undoped
heterostructure. Our data shows that the g-factor anisotropy for magnetic
fields applied along the high symmetry [011] direction can be explained by the
1D confinement only. However when the magnetic field is along [233] there is an
interplay between the 1D confinement and 2D crystal anisotropy. This is
highlighted for the [233] wire by an unusual non-monotonic behavior of the
g-factor as the wire is made narrower
Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo
TRPA1 is a nonselective cation channel, most famously expressed in nonmyelinated nociceptors. In addition to being an important chemical and mechanical pain sensor, TRPA1 has more recently appeared to have a role also in inflammation. Triterpenoids are natural products with anti-inflammatory and anticancer effects in experimental models. In this paper, 13 novel triterpenoids were created by synthetically modifying betulin, an abundant triterpenoid of the genus Betula L., and their TRPA1-modulating properties were examined. The Fluo 3-AM protocol was used in the initial screening, in which six of the 14 tested triterpenoids inhibited TRPA1 in a statistically significant manner. In subsequent whole-cell patch clamp recordings, the two most effective compounds (pyrazine-fused triterpenoids 8 and 9) displayed a reversible and dose- and voltage-dependent effect to block the TRPA1 ion channel at submicromolar concentrations. Interestingly, the TRPA1 blocking action was also evident in vivo, as compounds 8 and 9 both alleviated TRPA1 agonist-induced acute paw inflammation in mice. The results introduce betulin-derived pyrazine-fused triterpenoids as promising novel antagonists of TRPA1 that are potentially useful in treating diseases with a TRPA1-mediated adverse component
Electrically-Controlled Nuclear Spin Polarization and Relaxation by Quantum-Hall states
We investigate interactions between electrons and nuclear spins by using the
resistance (Rxx) peak which develops near filling factor n = 2/3 as a probe. By
temporarily tuning n to a different value, ntemp, with a gate, the Rxx peak is
shown to relax quickly on both sides of ntemp = 1. This is due to enhanced
nuclear spin relaxation by Skyrmions, and demonstrates the dominant role of
nuclear spin in the transport anomaly near n = 2/3. We also observe an
additional enhancement in the nuclear spin relaxation around n = 1/2 and 3/2,
which suggests a Fermi sea of partially-polarized composite fermions.Comment: 6 pages, 3 figure
Dissociation of vertical semiconductor diatomic artificial molecules
We investigate the dissociation of few-electron circular vertical
semiconductor double quantum dot artificial molecules at 0 T as a function of
interdot distance. Slight mismatch introduced in the fabrication of the
artificial molecules from nominally identical constituent quantum wells induces
localization by offsetting the energy levels in the quantum dots by up to 2
meV, and this plays a crucial role in the appearance of the addition energy
spectra as a function of coupling strength particularly in the weak coupling
limit.Comment: Accepted for publication in Phys. Rev. Let
Magnetization of a two-dimensional electron gas with a second filled subband
We have measured the magnetization of a dual-subband two-dimensional electron
gas, confined in a GaAs/AlGaAs heterojunction. In contrast to two-dimensional
electron gases with a single subband, we observe non-1/B-periodic, triangularly
shaped oscillations of the magnetization with an amplitude significantly less
than per electron. All three effects are explained by a
field dependent self-consistent model, demonstrating the shape of the
magnetization is dominated by oscillations in the confining potential.
Additionally, at 1 K, we observe small oscillations at magnetic fields where
Landau-levels of the two different subbands cross.Comment: 4 pages, 4 figure
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