Synthesis of Fused Polycyclic Indoles by Brønsted Acid-Catalyzed Intramolecular Alkylation of Indoles with Alcohols

An efficient methodology for the synthesis of a series of new fused polyclyclic indoles has been developed by Brønsted acidcatalyzed intramolecular Friedel−Crafts reactions of properly designed indolyl alcohols.Ministerio de Economiá y Competitividad (MINECO) and FEDER (CTQ2013-48937- C2-1-P) and Junta de Castilla y León (BU237U13

Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions

Iodine catalyzes the pseudo four-component reaction of an aldehyde, a urea or thiourea, and cyclic 1,3- dicarbonyl compounds under microwave irradiation in a solvent-free condition to yield various <3 symmetric spiro heterobicyclic rings in excellent yields

5-(3,4-Dimeth­oxy­benzyl­idene)-1,3-dimethyl-1,3-diazinane-2,4,6-trione

In the title compound, C15H16N2O5, the dihedral angle between 1,3-diazinane and benzene rings is only 4.27 (1)°. The essentially planar mol­ecular structure is characterized by a short intra­molecular C—H⋯O separation and by an exceptionally large bond angle of 138.25 (14)° at the bridging methine C atom. The meth­oxy groups deviate somewhat from the plane of the benzene ring, with C—C—O—C torsion angles of −15.6 (1) and 9.17 (6)°. In the crystal, mol­ecules form centrosymmetric dimers via donor–acceptor π–π inter­actions, with a centroid–centroid distance of 3.401 (1) Å

Dimethyl 2,6-dimethyl-4-phenyl­pyridine-3,5-dicarboxyl­ate

In the title compound, C17H17NO4, the dihedral angle between the benzene and pyridine rings is 75.51 (4)°. The benzene and pyridine rings are both approximately planar (r.m.s. deviations of 0.0040 and 0.0083 Å, respectively), indicating that the pyridine N atom is not protonated. The crystal structure is stabilized by weak inter­molecular C—H⋯O and C—H⋯N inter­actions

Racemic tricarbon­yl[7-meth­oxy-2-(η6-phen­yl)chromane]­chromium(0)

In the title compound, [Cr(C16H16O2)(CO)3], the Cr0 atom of the Cr(CO)3 unit is coordinated to the phenyl ring of the flavan ligand in an η6 mode, with a normal arene-to-metal distance. The Cr(CO)3 unit exhibits a three-legged piano-stool conformation, while the dihydro­pyran ring displays a distorted envelope configuration. The phenyl ring is twisted away from the fused ring system by 25.5 (2)°. The meth­oxy group is almost coplanar with the phenyl ring [CMe—O—Car—Car torsion angle = 8.46 (2)°]. The crystal packing is stabilized by inter­molecular C—H⋯O inter­actions

Indium trifluoromethanesulfonate (In(OTf)₃)-A new catalyst for Beckmann rearrangement of ketoximes and facile dehydration of aldoximes

154-156Indium trifluoromethanesulfonate is found to be an effective catalyst for the facile dehydration of aldoximes to nitriles and Beckmann rearrangement of ketoximes to anilides in excellent yields

4-(2-Bromophenyl)-2-phenylpyrano[3,2-c]chromen-5(4H)-one

In the title compound, C24H15BrO3, the pyranochromenone ring is essentially planar, while the 2-bromophenyl group is almost perpendicular to it [85.58&amp;#8197;(6)&amp;#176;]. In the crystal, inversion dimers linked by pairs of weak C&amp;#8212;H...&amp;#960; bonds occur; there is also a short interatomic contact found between the Br and carbonyl O atoms [3.016&amp;#8197;(1)&amp;#8197;&amp;#197;]

2,5-Dihexylthiophene 1,1-dioxide

In the title molecule, C16H28O2S, the two n-hexyl groups are in all-trans conformations. Their C atoms are situated close to the plane of the thiophene ring with a maximum deviation of 0.718&amp;#8197;(6)&amp;#8197;&amp;#197; for one of the terminal methyl groups. In the crystal, a short C&amp;#8212;H...O contact is observed between thiophene 1,1-dioxide groups