372 research outputs found

    With No Deliberate Speed: The Segregation of Roma Children in Europe

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    In this study, by taking the advantage of both inorganic ZnO nanoparticles and the organic material chitosan as a composite seed layer, we have fabricated well-aligned ZnO nanorods on a gold-coated glass substrate using the hydrothermal growth method. The ZnO nanoparticles were characterized by the Raman spectroscopic techniques, which showed the nanocrystalline phase of the ZnO nanoparticles. Different composites of ZnO nanoparticles and chitosan were prepared and used as a seed layer for the fabrication of well-aligned ZnO nanorods. Field emission scanning electron microscopy, energy dispersive X-ray, high-resolution transmission electron microscopy, X-ray diffraction, and infrared reflection absorption spectroscopic techniques were utilized for the structural characterization of the ZnO nanoparticles/chitosan seed layer-coated ZnO nanorods on a gold-coated glass substrate. This study has shown that the ZnO nanorods are well-aligned, uniform, and dense, exhibit the wurtzite hexagonal structure, and are perpendicularly oriented to the substrate. Moreover, the ZnO nanorods are only composed of Zn and O atoms. An optical study was also carried out for the ZnO nanoparticles/chitosan seed layer-coated ZnO nanorods, and the obtained results have shown that the fabricated ZnO nanorods exhibit good crystal quality. This study has provided a cheap fabrication method for the controlled morphology and good alignment of ZnO nanorods, which is of high demand for enhancing the working performance of optoelectronic devices

    Orbital aspergillus infection mimicking a tumour: a case report

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    A 14-year-old male presented to the neurosurgical clinic with swelling just above the right eye which had been growing slowly for the last eight years. The swelling first appeared following a non-penetrating trauma eight years ago. On examination it was a non-tender, non-erythematous, firm, round swelling causing marked proptosis and diplopia on downward gaze only. The visual acuity was intact. MRI showed an intraorbital, extraconal mass isointense on T1 and hypointense on T2 imaging. A diagnosis of orbital tumor was made. A white, friable mass consistent with meningioma was resected. However histopathology report later showed it to be an Aspergilloma. The patient was successfully treated with anti-fungal medicine and was disease-free at one year follow-up

    Correlation of Atrial Fibrillation with Left Atrial Volume in Patients with Mitral Stenosis. a Single Centre Study From Pakistan

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    Background: Rheumatic heart disease has a strong association with mitral valve stenosis. Atrial fibrillation is one of the most common complications of this condition and is a poor prognostic factor. Early detection and prompt management of atrial fibrillation can help to improve the quality of life and increase the life expectancy of the patients. We carried out this study to investigate the significance of left atrial volumetric changes in mitral stenosis and its correlation with atrial fibrillation. Methodology: We audited the data of 60 patients of rheumatic heart disease who had mitral valve stenosis. The patients were randomized into atrial fibrillation (Group A) and normal sinus rhythm (Group B). We conducted this cross-sectional analytical study at Cardiology Department, Mayo Hospital, Lahore, from 1st February 2017 to 31st January 2018. We only included those patients who consented to be a part of this study and fulfilled our predefined inclusion criteria. Left atrial volume was measured by prolate ellipse method and biplane methods on echocardiography. The Data was analyzed on SPSS v20. Results: Sixty patients were included in the study. Among the subjects, thirty-six (60%) were males, and twenty-four (40%) were females. Atrial fibrillation was noted in 43.33% of the patients of mitral valve stenosis. There was a marked difference in the mean volume of the left atrium among the two groups. We observed that the mean area of the mitral valve for Group A patients was larger than that of patients in Group B. Our study showed an inverse correlation between left atrial volume and mitral valve area among Group A patients. Conclusion: Patients of mitral stenosis are at an increased risk of developing atrial fibrillation if the left atrial volume is increasing. All patients with mitral stenosis should have routine echocardiography & measurement of left atrial volumes, so that proper treatment can be started if the left atrial volume is increasing, to prevent atrial fibrillation

    Inhibition of Hepatitis C Virus 3a genotype entry through Glanthus Nivalis Agglutinin

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    <p>Abstract</p> <p>Background</p> <p>Hepatitis C Virus (HCV) has two envelop proteins E1 and E2 which is highly glycosylated and play an important role in cell entry. Inhibition of virus at entry step is an important target to find antiviral drugs against HCV. Glanthus Nivalis Agglutinin (GNA) is a mannose binding lectin which has tendency for specific recognition and reversible binding to the sugar moieties of a wide variety of glycoproteins of enveloped viruses.</p> <p>Results</p> <p>In the present study, HCV pseudoparticles (HCVpp) for genotype 3a were produced to investigate the ability of GNA to block the HCV entry. The results demonstrated that GNA inhibit the infectivity of HCVpp and HCV infected serum in a dose-dependent manner and resulted in 50% reduction of virus at 1 ± 2 μg concentration. Molecular docking of GNA and HCV glycoproteins (E1 and E2) showed that GNA inhibit HCV entry by binding N-linked glycans.</p> <p>Conclusion</p> <p>These results demonstrated that targeting the HCV glycans is a new approach to develop antiviral drugs against HCV.</p

    Traumatic carotid-cavernous fistula: Clinical presentation and outcome

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    Objective:To evaluate the presentation, clinical course and outcome of traumatic carotid-cavernous fistula (CCF) withendovascular treatment at our institution during the last five years. Design: Retrospective descriptive study. Setting: The study included patients seen at Aga Khan University Hospital from January 2000 to December 2005. Methods: Retrospective analysis based on data retrieval from medical records using ICD coding system. Only those cases who had traumatic CCF and underwent endovascular treatment were included in the study. Results: A total of 8 patients were diagnosed with post-traumatic CCF and 11 procedures were done. Mean age at presentation was 35.6 years; mean duration of symptoms was 23 weeks after trauma; 6 patients were male and 2 female. Patients presented from 1 week to 2 years after the trauma; 7 had high-flow fistulas and 1 had low-flow fistula. Proptosis was the most common symptom (6 patients); decreased vision was present in 3 patients; 4 patients had an accompanying skull base fracture; and 1 patient had bilateral CCF. All patients were treated by endovascular procedures; 2 patients had recurrences, seen within 1 month of initial treatment and subsequently successfully treated. In 1 patient, the procedure failed due to the small size of the fistula. Conclusion: High success rate with minimal complications as seen in our series supports endovascular treatment as the leading option for CCF managemen

    Optimal Distribution of Renewable Energy Systems Considering Aging and Long-Term Weather Effect in Net-Zero Energy Building Design

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    Generation system interruptions in net-zero energy buildings (NZEBs) may result in missing the net-zero targets by a great margin. Consequently, it is significant to incorporate a realistic reliability model for renewable energy systems (RESs) that considers aging and long-term weather conditions. This study proposed a robust design optimization method that deals with the selection of RES to achieve NZEB. Different case studies were evaluated: 1. Deterministic approach; 2. Markov chain-based reliability without the aging effect; 3. Markov chain-based reliability with the aging effect. The results showed that the optimal sizes of RES, considering the aging effect, were much larger than the other two cases based on the annual energy balance. Moreover, the consideration of the aging effect on the reliability assessment of the generation system for NZEB opens a pathway for a more robust and economic design of RES

    A Critical Review of Sustainable Energy Policies for the Promotion of Renewable Energy Sources

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    Meeting the rising energy demand and limiting its environmental impact are the two intertwined issues faced in the 21st century. Governments in different countries have been engaged in developing regulations and related policies to encourage environment friendly renewable energy generation along with conservation strategies and technological innovations. It is important to develop sustainable energy policies and provide relevant and suitable policy recommendations for end-users. This study presents a review on sustainable energy policy for promotion of renewable energy by introducing the development history of energy policy in five countries, i.e., the United States, Germany, the United Kingdom, Denmark and China. A survey of the articles aimed at promoting the development of sustainable energy policies and their modelling is carried out. It is observed that energy-efficiency standard is one of the most popular strategy for building energy saving, which is dynamic and renewed based on the current available technologies. Feed-in-tariff has been widely applied to encourage the application of renewable energy, which is demonstrated successfully in different countries. Building energy performance certification schemes should be enhanced in terms of reliable database system and information transparency to pave the way for future net-zero energy building and smart cities

    Human object annotation for surveillance video forensics

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    A system that can automatically annotate surveillance video in a manner useful for locating a person with a given description of clothing is presented. Each human is annotated based on two appearance features: primary colors of clothes and the presence of text/logos on clothes. The annotation occurs after a robust foreground extraction stage employing a modified Gaussian mixture model-based approach. The proposed pipeline consists of a preprocessing stage where color appearance of an image is improved using a color constancy algorithm. In order to annotate color information for human clothes, we use the color histogram feature in HSV space and find local maxima to extract dominant colors for different parts of a segmented human object. To detect text/logos on clothes, we begin with the extraction of connected components of enhanced horizontal, vertical, and diagonal edges in the frames. These candidate regions are classified as text or nontext on the basis of their local energy-based shape histogram features. Further, to detect humans, a novel technique has been proposed that uses contourlet transform-based local binary pattern (CLBP) features. In the proposed method, we extract the uniform direction invariant LBP feature descriptor for contourlet transformed high-pass subimages from vertical and diagonal directional bands. In the final stage, extracted CLBP descriptors are classified by a trained support vector machine. Experimental results illustrate the superiority of our method on large-scale surveillance video data
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