Security Policies and Mechanisms for Vehicular Delay Torlant Network

This article revision the literature related to Vehicular Delay Tolerant Network with focus on Cooperation. It starts by examining definitions of some of the fields of research in VDTN on security policies. An overview of VDTN on security policies cooperative networks is presented. A security policy is a high-level specification of the security properties that a given system should possess. It is a means for designers domain experts and implementers to communicate with each other, and a blueprint that drives a project from design through implementation and validation. We offer a survey of the most significant security policy models in the literature showing security may mean very different things in different contexts and we review some of the mechanisms used to implement a gievn security policy

Security Policies and Mechanisms for Vehicular Delay Torlant Network

This article revision the literature related to Vehicular Delay Tolerant Network with focus on Cooperation. It starts by examining definitions of some of the fields of research in VDTN on security policies. An overview of VDTN on security policies cooperative networks is presented. A security policy is a high-level specification of the security properties that a given system should possess. It is a means for designers domain experts and implementers to communicate with each other, and a blueprint that drives a project from design through implementation and validation. We offer a survey of the most significant security policy models in the literature showing security may mean very different things in different contexts and we review some of the mechanisms used to implement a gievn security policy

Defining timeliness in care for patients with lung cancer : a scoping review

Objectives Early diagnosis and reducing the time taken to achieve each step of lung cancer care is essential. This scoping review aimed to examine time points and intervals used to measure timeliness and to critically assess how they are defined by existing studies of the care seeking pathway for lung cancer. Methods This scoping review was guided by the methodological framework for scoping reviews by Arksey and O'Malley. MEDLINE, EMBASE, CINAHL and PsycINFO electronic databases were searched for articles published between 1999 and 2019. After duplicate removal, all publications went through title and abstract screening followed by full text review and inclusion of articles in the review against the selection criteria. A narrative synthesis describes the time points, intervals and measurement guidelines used by the included articles. Results A total of 2113 articles were identified from the initial search. Finally, 68 articles were included for data charting process. Eight time points and 14 intervals were identified as the most common events researched by the articles. Eighteen different lung cancer care guidelines were used to benchmark intervals in the included articles; all were developed in Western countries. The British Thoracic Society guideline was the most frequently used guideline (20%). Western guidelines were used by the studies in Asian countries despite differences in the health system structure. Conclusion This review identified substantial variations in definitions of some of the intervals used to describe timeliness of care for lung cancer. The differences in healthcare delivery systems of Asian and Western countries, and between high-income countries and low-income-middle-income countries may suggest different sets of time points and intervals need to be developed.

Defining timeliness in care for patients with lung cancer : protocol for a scoping review

Introduction Cancer is the second leading cause of death worldwide, and lung cancer is the single leading cause of cancer mortality worldwide. Early diagnosis of lung cancer is the key to better prognosis and longer survival. While there are substantial literature reporting delays in cancer diagnosis, there is a lack of consensus in the definitions and terms used to describe a € delay' in the treatment pathway. The aim of this scoping review is to identify and critically synthesise the operational definitions and terminologies used to describe the timely initiation of care and consequent treatments over the care pathway for patients with lung cancer. This scoping review will also compare how timeliness was operationalised in Western and Asian countries. Methods and analysis The scoping review will use the methodology described by Arksey and O'Malley and endorsed by the Joanna Briggs Institute. MEDLINE, EMBASE, CINAHL and PsycINFO electronic databases will be searched. Grey literature sources and the reference lists of key studies will be used to identify additional relevant studies. The scoping review will include all studies, irrespective of study methodology and quality. Two reviewers will independently screen all titles and abstracts to identify eligible studies for inclusion. The full texts of identified studies will be further examined and charted using a data extraction form. A narrative synthesis will be performed to assess and categorise available definitions of timeliness. Ethics and dissemination Ethical approval is not needed as this scoping review will be reviewing already published articles. The results produced from this review will be submitted to a scientific peer-reviewed journal for publication and will be presented at scientific meetings.

A Novel Dynamic Appliance Clustering Scheme in a Community Home Energy Management System for Improved Stability and Resiliency of Microgrids

Power scheduling of domestic appliances is a vital preference for bridging the gap between demand and generation of electricity in a microgrid. For a stable microgrid, an acceptable mechanism must reduce the peak to average ratio (PAR) of power demand with supplementary benefits for consumers as reduced electricity charges. Recent studies have focused on PAR and cost reduction for a small consumer population. Furthermore, researchers have mainly considered homogeneous consumer loads. This study focuses on residential power scheduling for electricity cost reduction for consumers and load profile PAR curtailment for a relatively large consumer population with non-homogeneous loads. A sample population of 1000 consumers from various classes of society is considered. The proposed dynamic clustered community home energy management system (DCCHEMS) allows the clustering of appliances based on time overlap criteria. Comparatively flatter power demand is attained by utilizing the clustered appliances in conjunction with particle swarm optimization under the influence of user-defined constraints. Modified inclined block rates with real-time electricity pricing strategies are deployed to minimize the electricity costs. DCCHEMS achieved higher efficiency rates in contrast to the traditional non-clustering and static clustering optimization schemes. An improvement of 21% in peak to average ratio, 4% in cost reduction, and 19% in variance to mean ratio is obtained

Flexible and scalable software defined radio based testbed for large scale body movement

Human activity (HA) sensing is becoming one of the key component in future healthcare system. The prevailing detection techniques for IHA uses ambient sensors, cameras and wearable devices that primarily require strenuous deployment overheads and raise privacy concerns as well. This paper proposes a novel, non-invasive, easily-deployable, flexible and scalable test-bed for identifying large-scale body movements based on Software Defined Radios (SDRs). Two Universal Software Radio Peripheral (USRP) models, working as SDR based transceivers, are used to extract the Channel State Information (CSI) from continuous stream of multiple frequency subcarriers. The variances of amplitude information obtained from CSI data stream are used to infer daily life activities. Different machine learning algorithms namely K-Nearest Neighbour, Decision Tree, Discriminant Analysis and Naïve Bayes are used to evaluate the overall performance of the test-bed. The training, validation and testing processes are performed by considering the time-domain statistical features obtained from CSI data. The K-nearest neighbour outperformed all aforementioned classifiers, providing an accuracy of 89.73%. This preliminary non-invasive work will open a new direction for design of scalable framework for future healthcare systems

Pengetahuan, sikap & amalan pengguna media sosial ke atas gangguan seksual siber di Lembah Klang

Gangguan seksual siber adalah satu jenayah yang perlu diberi perhatian serius oleh semua pihak kerana dengan bantuan teknologi zaman sekarang, semua individu yang berada dalam talian berpontensi untuk menjadi mangsa kepada gangguan seksual siber tanpa mengira demografi seseorang. Lazimnya gangguan seksual siber bermula apabila pelaku memancing mangsa berbual perkara berunsurkan lucah dan kotor. Jenayah ini boleh memberikan impak kepada mangsa dari segi kesihatan mental. Menerima gangguan seksual siber boleh menjejaskan emosi mangsa kerana rasa takut, risau dan trauma yang mungkin mendatangkan gangguan tekanan pasca trauma yang selalunya terjadi selepas individu mengalami peristiwa yang traumatik. Pengetahuan pengguna media sosial yang baik tentang kewujudan gangguan seksual siber ini mampu memberikan pendedahan tentang isu ini kepada masyarakat umum. Selain itu, sikap serta amalan yang baik perlu dipupuk dalam kalangan pengguna media sosial untuk menangani masalah gangguan ini. Justeru kajian ini berobjektifkan untuk membincangkan pengetahuan, sikap dan amalan pengguna media sosial terhadap isu gangguan seksual siber. Kajian ini berjaya menemu bual seramai 18 orang pengguna media sosial secara berkumpulan dengan menggunakan pendekatan kualitatif. Hasil kajian menunjukkan bahawa para informan mempunyai pengetahuan yang baik tentang jenayah ini, malah kaum lelaki juga sering menjadi mangsa gangguan seksual siber ini. Selain itu, dapatan juga menunjukkan masyarakat harus mengelak sikap perbuatan menghukum lebih awal terhadap seseorang terutamanya kepada mangsa gangguan seksual siber. Di samping itu, kajian juga mendapati masyarakat perlu berani ke hadapan untuk membuat laporan kepada agensi yang berkaitan agar pelaku mendapat pengajaran yang cukup dan masyarakat juga akan sedar tentang kewujudan jenayah siber ini

Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6- yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl) acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study

The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presence of 10% aqueous Na2CO3 to yield N-(2,3-dihydrobenzo[1,4]-dioxin-6-yl)-4-methylbenzenesulfonamide (3), which was then reacted with 2-bromo-N-(un/substituted-phenyl)acetamides (6a-l) in DMF and lithium hydride as a base to afford various 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl)sulfonyl] amino}-N-(un/substituted-phenyl)acetamides (7a-l). All the synthesized compounds were characterized by their IR and 1 H-NMR spectral data along with CHN analysis data. The enzyme inhibitory activities of these compounds were tested against -glucosidase and acetylcholinesterase (AChE). Most of the compounds exhibited substantial inhibitory activity against yeast -glucosidase and weak against AChE. The in silico molecular docking results were also consistent with in vitro enzyme inhibition data

Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides

A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and lipoxygenase activity as well. 2,4-Dimethylcarbolic acid (1) was refluxed with ethyl 2-bromoacetate to synthesize ethyl 2-(2,4-dimethylphenoxy)acetate (2). Compound 2 was converted to the corresponding hydrazide 3, again on refluxing with hydrazine. The compound 5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-thiol (4) was synthesized by the reaction of 3 and CS2 in the presence of KOH. Compound 4 was further converted to the corresponding ester 5 and then 2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazide (6). The final molecules N'-substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazide, 8a-m, bearing ether, 1,3,4-oxadiazole, thioether, hydrazone and azomethine functional groups were synthesized by stirring the aryl carboxaldehydes 7a-m with 6 in methanol at room temperature. The depicted structures of all synthesized molecules were corroborated by IR, 1H-NMR and EIMS spectral data analysis. 8m and 8i showed substantial antibacterial activity and lipoxygenase inhibitory activity, respectively

Synthesis, Characterization, Antibacterial, α-Glucosidase Inhibition and Hemolytic Studies on Some New N-(2,3- Dimethylphenyl)benzenesulfonamide Derivatives

Purpose: To synthesize a series of new N-(2,3-dimethylphenyl)benzenesulfonamide derivatives with pharmacological analysis.Methods: N-(2,3-Dimethylphenyl)benzenesulfonamide (3) was synthesized by the reaction between 2,3-dimethylaniline (1) and benzenesulfonyl chloride (2) in aqueous basic medium. Compound 3 was further treated with various alkyl/aralakyl halides (4a-m) to yield new compounds, 5a-m, in a weak basic aprotic polar organic medium. The proposed structures of synthesized compounds were confirmed using proton-nuclear magnetic resonance (1H-NMR), infra red spectroscopy (IR) and electron impact mass spectrometry (EIMS). The synthesized compounds were screened for in vitro antibacterial, antienzymatic and hemolytic activities using standard procedures.Results: All the synthesized compounds showed moderate to high activity against Gram-positive and Gram-negative bacterial strains. The molecules 5g and 5j exhibited good inhibition of α-glucosidase enzyme with half-maximal inhibitory concentration (IC50) of 59.53 ± 0.01 and 55.31 ± 0.01 μmoles/L, respectively, relative to acarbose with IC50 of 38.25 ± 0.12 μmoles/L. All the compounds exhibited cytotoxicity levels ranging from 27.20 ± 0.24 to 5.20 ± 0.41 %, relative to Triton X-100.Conclusion: Compound 5f is the most potent antibacterial while 5j is the best α-glucosidase inhibitor; 5e showed the least cytotoxicity.Keywords: 2,3-Dimethylaniline, Antibacterial activity, Anti-enzymatic activity, α-Glucosidase inhibitor, Hemolytic activity, Sulfonamide