204 research outputs found

    Dietary Intake, Nutritional Adequacy, and Food Sources of Protein and Relationships with Personal and Family Factors in Spanish Children Aged One to <10 Years: Findings of the EsNuPI Study

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    This research was funded by Instituto Puleva de Nutricion (IPN), which is a non-profit entity that promotes scientific research, mainly in the field of nutrition and health: child nutrition, cardiovascular, bone and digestive health, etc., as well as the dissemination of quality scientific content. While the IPN is funded by the dairy company Lactalis, its actions are based on the decisions of an independent scientific board formed by renowned international scientists. A. G. is co-financed by the Research Plan of the Vice-Rectorate of Research and Transfer of the University of Granada, Spain.The authors would like to thank IPN for its support and technical advice. The results presented in this article constitute part of Casandra Madrigal Arellano’s doctoral thesis, performed in the Nutrition and Food Sciences Doctorate Program of the University of Granada and financed by the Consejo Nacional de Ciencia y Tecnología (CONACYT).Diet in the first years of life is an important factor in growth and development. Dietary protein is a critical macronutrient that provides both essential and nonessential amino acids required for sustaining all body functions and procedures, providing the structural basis to maintain life and healthy development and growth in children. In this study, our aim was to describe the total protein intake, type and food sources of protein, the adequacy to the Population Reference Intake (PRI) for protein by the European Food Safety Authority (EFSA), and the Recommended Dietary Allowance (RDA) by the Institute of Medicine (IoM). Furthermore, we analyzed whether the consumption of dairy products (including regular milk, dairy products, or adapted milk formulas) is associated with nutrient adequacy and the contribution of protein to diet and whole dietary profile in the two cohorts of the EsNuPI (in English, Nutritional Study in the Spanish Pediatric Population) study; one cohort was representative of the Spanish population from one to <10 years old (n = 707) (Spanish reference cohort, SRS) who reported consuming all kinds of milk and one was a cohort of the same age who reported consuming adapted milk over the last year (including follow-on formula, growing up milk, toddler's milk, and enriched and fortified milks) (n = 741) (adapted milk consumers cohort, AMS). The children of both cohorts had a high contribution from protein to total energy intake (16.79% SRS and 15.63% AMS) and a high total protein intake (60.89 g/day SRS and 53.43 g/day AMS). We observed that protein intake in Spanish children aged one to <10 years old was above the European and international recommendations, as well as the recommended percentages for energy intakes. The main protein sources were milk and dairy products (28% SRS and 29% AMS) and meat and meat products (27% SRS and 26% AMS), followed by cereals (16% SRS and 15% AMS), fish and shellfish (8% in both cohorts), eggs (5% SRS and 6% AMS), and legumes (4% in both cohorts). In our study population, protein intake was mainly from an animal origin (meat and meat products, milk and dairy products, fish and shellfish, and eggs) rather than from a plant origin (cereals and legumes). Future studies should investigate the long-term effect of dietary protein in early childhood on growth and body composition, and whether high protein intake affects health later in life.Instituto Puleva de Nutricion (IPN)dairy company LactalisResearch Plan of the Vice-Rectorate of Research and Transfer of the University of Granada, Spai

    Obesidad y sedentarismo en el siglo XXI: ¿qué se puede y se debe hacer?

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    En la actualidad, seis de los siete principales factores de riesgo de mortalidad prematura en Europa (presión sanguínea, colesterol, Índice de Masa Corporal, ingesta insuficiente de fruta y verdura, inactividad física y abuso del alcohol) están relacionados con los estilos de vida, especialmente con los hábitos alimentarios, el consumo de alcohol y la inactividad física y/o sedentarismo. En el ámbito de la salud pública es especialmente preocupante el aumento del sobrepeso y la obesidad en toda Europa. Para abordar este problema, tanto la Organización Mundial de la Salud (OMS) como la Comisión Europea abogan por un enfoque integrado, con la implicación de las partes interesadas a nivel europeo, nacional, regional y local. Sirva como magnífico ejemplo la muy reciente Declaración de Viena sobre Nutrición y Enfermedades No Transmisibles que la OMS promulgó tras la Conferencia Ministerial celebrada en Viena los pasados 4 y 5 de julio del 2013, en el contexto del programa “Health 2020”, en la que se reafirma el imprescindible abordaje multidisciplinar

    Usual Dietary Intake, Nutritional Adequacy and Food Sources of Calcium, Phosphorus, Magnesium and Vitamin D of Spanish Children Aged One to <10 Years. Findings from the EsNuPI Study †

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    The authors would like to thank IPN for its support and technical advice.Bone problems in the population begin to be establish in childhood. The present study aims to assess the usual calcium, phosphorus, magnesium, and vitamin D intakes, along with the food sources of these nutrients, in Spanish children participating in the EsNuPI (Estudio Nutricional en Población Infantil Española) study. Two 24 h dietary recalls were applied to 1448 children (1 to <10 years) divided into two sub-samples: one reference sample (RS) of the general population [n = 707] and another sample which exclusively included children consuming enriched or fortified milks, here called “adapted milks” (AMS) [n = 741]. Estimation of the usual intake shows that nutrient intake increased with age for all nutrients except vitamin D. Using as reference the Dietary Reference Values from the European Food Safety Authority (EFSA), calcium and magnesium intakes were found to be below the average requirement (AR) and adequate intake (AI), respectively, in a considerable percentage of children. Furthermore, phosphorus exceeded the AI in 100% of individuals and vitamin D was lower than the AI in almost all children studied. The results were very similar when considering only plausible reporters. When analyzing the food sources of the nutrients studied, milk and dairy products contributed the most to calcium, phosphorus, magnesium, and vitamin D. Other sources of calcium were cereals and vegetables; for phosphorus: meat, meat products, and cereals; for magnesium: cereals and fruits; and, for vitamin D: fish and eggs. These results highlight the desirability of improving the intake concerning these nutrients, which are involved in bone and metabolic health in children. The AMS group appeared to contribute better to the adequacy of those nutrients than the RS group, but both still need further improvement. Of special interest are the results of vitamin D intakes, which were significantly higher in the AMS group (although still below the AI), independent of age.Instituto Puleva de Nutricion (IPN

    Dietary Intake of Individual (Intrinsic and Added) Sugars and Food Sources from Spanish Children Aged One to <10 Years—Results from the EsNuPI Study

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    This research was funded by Instituto Puleva de Nutricion (IPN), which is a non-profit entity that promotes scientific research, mainly in the field of nutrition and health: child nutrition, cardiovascular, bone and digestive health, etc., as well as the dissemination of quality scientific content. While the IPN is funded by the dairy company Lactalis, its actions are based on the decisions of an independent scientific board formed by renowned international scientists. a. G. is co-financed by the Research Plan of the Vice-Rectorate of Research and Transfer of the University of Granada, Spain.Currently, in Spain there are no studies assessing the intakes and sources of intrinsic and added sugars by both children consuming standard milks and children regularly consuming adapted milk formulas. Our goal was to evaluate current sugar intake levels (intrinsic and added) and their major dietary sources within the EsNuPI study participants by applying two 24-h dietary recalls that were completed by 1448 children (1 to <10 years) divided into two subsamples: One “Spanish Reference Sample” (SRS) of the general population (n = 707) and another sample which included children consuming adapted milks including follow-on milk, toddler’s or growing up milk and fortified and enriched milks, here called “Adapted Milk Consumers Sample” (AMS) (n = 741). Estimates of intrinsic and added sugar intakes from the Spanish EsNuPI population as well as the adherence to recommendations varied notably according to age segment, but no major differences between subsamples were found. Younger children (1 to <3 years) showed the highest added sugar contribution to total energy intake (TEI) (SRS: 12.5% for boys and 11.7% for girls; AMS: 12.2% for boys and 11.3% for girls) and the lowest adherence to recommendations set at <10% TEI (SRS: 27.4% for boys and 37.2% for girls; AMS: 31.3% for boys and 34.7% for girls). Adherence increased with age but remains inadequate, with approximately one in two children from the older age segment (6 to <10 years) exceeding the recommendations. Main food sources of intrinsic sugars for both subsamples were milk and dairy products, fruits, vegetables and cereals, while for added sugars, these were milk and dairy products (mainly yogurts), sugars and sweets (mainly sugary cocoa and nougat), bakery products (mainly cookies) and cereals (mainly bread and wheat flour). However, for the AMS, the groups milk and dairy products and cereals showed a significantly lower contribution to intrinsic sugar intake but a significantly higher contribution to that of added sugars. These results demonstrate that sugar intake and the adherence to recommendations in the studied population varied notably according to age but not to the type of milk consumed. In addition, our results highlight the need to monitor the consumption of added sugars by the infant population, as well as the need to make efforts to facilitate this task, such as harmonizing the recommendations regarding free/added sugars and the inclusion of information on their content on the nutritional labeling of products in order to incorporate them into food composition databases.Instituto Puleva de Nutrición (IPN)dairy company LactalisResearch Plan of the Vice-Rectorate of Research and Transfer of the University of Granada, Spai

    Global monitoring of soil multifunctionality in drylands using satellite imagery and field data

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    Models derived from satellite image data are needed to monitor the status of terrestrial ecosystems across large spatial scales. However, a remote sensing-based approach to quantify soil multifunctionality at the global scale is missing despite significant research efforts on this topic. A major constraint for doing so is the availability of suitable global-scale field data to calibrate remote sensing indicators (RSI) and, to a lesser extent, the sensitivity of spectral data of available satellite sensors to soil background and atmospheric conditions. Here, we aimed to develop a soil multifunctionality model to monitor global drylands coupling ground data on 14 soil functions of 222 dryland areas from six continents to 18 RSI derived from a time series (2006–2013) Landsat dataset. Among the RSI evaluated, the chlorophyll absorption ratio index was the best predictor of soil multifunctionality in single-variable-based models (r = 0.66, P < 0.01, NMRSE = 0.17). However, a multi-variable RSI model combining the chlorophyll absorption ratio index, the global environment monitoring index and the canopy-air temperature difference improved the accuracy of quantifying soil multifunctionality (r = 0.73, P < 0.01, NMRSE = 0.15). Furthermore, the correlation between RSI and soil variables shows a wide range of accuracy with upper and lower values obtained for AMI (r = 0.889, NMRSE = 0.05) and BGL (r = 0.685, NMRSE = 0.18) respectively. Our results provide new insights on assessing soil multifunctionality using RSI that may help to monitor temporal changes in the functioning of global drylands effectively.Field data were obtained with the support of the European Research Council (ERC) grant agreement 242658 (BIOCOM). Hernández-Clemente R was supported by the Ramón y Cajal program (RYC2020-029187-I) and the State Plan for Scientific and Subprogram for Knowledge Generation (PID2021-124058OA-I00) from the Spanish Ministry of Science and Innovation (RYC2020-029187-I). Maestre FT acknowledges support from Generalitat Valenciana (CIDEGENT/2018/041) and the Spanish Ministry of Science and Innovation (EUR2022-134048)

    An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents beta-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans

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    The authors gratefully acknowledge the funding support of FEDER/Junta de AndaluciaConsejeria de Economia y Conocimiento, Grant B-AGR-193-UGR18. Also grant PID2019-106778RBI00, funded by MCIN/AEI/10.13039/501100011033 FEDER "Una manera de hacer Europa".Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extract 20% rich in hydroxytyrosol on the molecular mechanisms associated with Alzheimer disease features like A beta- and tau- induced toxicity, as well as on oxidative stress in Caenorhabditis elegans. Moreover, characterization of the extracts, regarding the profile and content of phenolics, as well as total antioxidant ability, was investigated. The study of lethality, growth, pharyngeal pumping, and longevity in vivo demonstrated the lack of toxicity of the extract. One hundred mu g/mL of extract treatment revealed prevention of oxidative stress and a delay in A beta-induced paralysis related with a lower presence of A beta aggregates. Indeed, the extract showed the ability to avoid a certain degree of proteotoxicity associated with aggregation of the tau protein. According to RNAi tests, SKN-1/NRF2 transcription factor and the overexpression of HSP-16.2 were mechanistically associated in the observed effects.FEDER/Junta de AndaluciaConsejeria de Economia y Conocimiento B-AGR-193-UGR18 PID2019-106778RBI00 MCIN/AEI/10.13039/50110001103

    Gastronomic, food and nutritional aspects of oriental Andalusia

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    Andalucía oriental se denomina Alta Andalucía por la elevada orografía de las cordilleras Béticas con las cumbres peninsulares más altas. Surge con la segmentación de España en provincias, e incluye Almería, Granada, Jaén y Málaga. Solo hay que detenerse en el fondo de nuestras ollas para encontrarnos el sincretismo de las tres grandes religiones monoteístas (árabe, judía y cristiana) que mezcló las fiestas de una con las comidas de otra y permitió la universalización de sus gastronomías; un sincretismo que ha llegado hasta hoy y hace difícil conocer el origen de una u otra receta. La cocina busca hoy la fusión entre el sabor y los ingredientes de la cocina tradicional con el saber y la técnica de la cocina moderna. La diversidad geográfica y climática de Andalucía oriental es proporcional a su despensa, y esta es la que surte su recetario. La población de Andalucía oriental se aparta del patrón mediterráneo y se acerca a la dieta global de los países desarrollados de Occidente. Esta tendencia a disminuir el consumo de alimentos propios de patrón mediterráneo parece mantenerse, aunque se observa una disminución en la caída de alguno de ellos. Además, el consumo elevado de grupos como el de carnes y derivados, bollería, dulces y azúcar tiende a moderarse. El patrón actual es compatible –como pone de manifiesto el estudio ANIBES– con unas ingestas elevadas de grasa saturada y total y de azúcares y una baja ingesta de fibra en un porcentaje importante de la población en España y, por tanto, en Andalucía.Eastern Andalusia, is also named Highland Andalusia, because the elevated orography of the Betics mountain range, with the highest Iberian Peninsula summits. This region arose with the division of the Spanish territory by provinces and currently includes Almeria, Granada, Jaen. You should only stop and look into the bottom of our cooking pots to find the syncretism of the three monotheistic religions, Christianity, Jewish and Muslin, which mixed parties of each one with meals of the others, thus allowing the globalization of their gastronomies that remained until nowadays and makes difficult to find the actual origin of a particular meal recipe. Modern cooking tries to find the fusion between tastes and ingredients of traditional cooking with current knowledge and technology. The geographic and climate diversities in Eastern Andalusia are proportional to its pantry, which in turn is the source of its meal recipes. The population of Eastern Andalusia is moving away of the Mediterranean pattern and getting closer to the developed Western countries diet. This trend to decrease the consumption of proprietary Mediterranean foods seems to be maintained in the last years although some of them start to recover. In addition, some food groups e.g. meat and meat derivatives, pastries and sweets, with actual elevated consumption, tend to be moderated. The current food pattern for the whole Spanish population, as well as for Eastern Andalusia, is compatible with high intakes of saturated fat, and total and free sugars, and low intakes of fiber in a high percentage of the Spanish population as reported by the ANIBES study

    Non-Excitatory Amino Acids, Melatonin, and Free Radicals: Examining the Role in Stroke and Aging

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    The aim of this review is to explore the relationship between melatonin, free radicals, and non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered significant attention in recent years due to its diverse physiological functions and potential therapeutic benefits by reducing oxidative stress, inflammation, and apoptosis. Melatonin has been found to mitigate ischemic brain damage caused by stroke. By scavenging free radicals and reducing oxidative damage, melatonin may help slow down the aging process and protect against age-related cognitive decline. Additionally, non-excitatory amino acids have been shown to possess neuroprotective properties, including antioxidant and anti-inflammatory in stroke and aging-related conditions. They can attenuate oxidative stress, modulate calcium homeostasis, and inhibit apoptosis, thereby safeguarding neurons against damage induced by stroke and aging processes. The intracellular accumulation of certain non-excitatory amino acids could promote harmful effects during hypoxia-ischemia episodes and thus, the blockade of the amino acid transporters involved in the process could be an alternative therapeutic strategy to reduce ischemic damage. On the other hand, the accumulation of free radicals, specifically mitochondrial reactive oxygen and nitrogen species, accelerates cellular senescence and contributes to age-related decline. Recent research suggests a complex interplay between melatonin, free radicals, and non-excitatory amino acids in stroke and aging. The neuroprotective actions of melatonin and non-excitatory amino acids converge on multiple pathways, including the regulation of calcium homeostasis, modulation of apoptosis, and reduction of inflammation. These mechanisms collectively contribute to the preservation of neuronal integrity and functions, making them promising targets for therapeutic interventions in stroke and age-related disorders.This work was supported by MICIU (grant number PID2021-128133NB-I00/AEI/FEDER10.13039/501100011033) to J.M.H.-G. and V.J.C. enjoys a contract from the CAM “Investigo” program (PIP/2022-09971). A.R. thanks UCJC (INFLAMAMEL 2022-07 project) for its continued support

    Guia de estilos de vida saudáveis da FINUT: além da pirâmide alimentar

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    La Organización Mundial de la Salud (World Health Organization: OMS) ha propuesto que la salud debe ser promovida y protegida a través del desarrollo de un medio ambiente que permita acciones sostenibles a nivel individual, comunitario, nacional y global. De hecho, se han desarrollado en numerosos países guías alimentarias (por ejemplo, las pirámides de alimentos) para divulgar información nutricional a la población general. Sin embargo, se necesitan recomendaciones más amplias sobre estilos activos de vida saludable, no restringidos únicamente a los alimentos. El objetivo de este trabajo es la propuesta de una pirámide tridimensional como una nueva estrategia para promover una nutrición adecuada y estilos activos de vida saludable de manera sostenible. En efecto, se ha diseñado la pirámide FINUT (Fundación Iberoamericana de Nutrición) sobre estilos de vida saludable como un tetraedro cuyas tres caras laterales se corresponden a los binomios alimentación y nutrición, actividad física y descanso, y educación e higiene. Cada cara lateral está dividida en dos triángulos. Estas caras muestran lo siguiente: 1. guías alimentarias y hábitos de alimentación saludable en relación a un medio ambiente sostenible; 2. recomendaciones sobre descanso y actividad física y temas de educación, sociales y culturales relacionados; 3. guías seleccionadas sobre higiene y educación que, en conjunto con las otras dos caras, puedan contribuir a una mejor salud para la población en un planeta sostenible. La nueva pirámide FINUT se dirige a la población general de todas las edades y debería servir como una guía para un estilo de vida saludable en un contexto social y cultural definido. La pirámide incluye una dimensión ambiental y sostenible que proporciona medidas para contribuir a la prevención de las enfermedades crónicas no transmisibles.The World Health Organization has proposed that health be promoted and protected through the development of an environment that enables sustainable actions at individual, community, national and global levels. Indeed, food-based dietary guidelines, i.e., food pyramids, have been developed in numerous countries to disseminate nutritional information to the general population. However, wider recommendations are needed, with information on an active, healthy lifestyle, not just healthy eating. The objective of the present work is to propose a three-dimensional pyramid as a new strategy for promoting adequate nutrition and active healthy lifestyles in a sustainable way. Indeed, the Iberomerican Nutrition Foundation (FINUT) pyramid of healthy lifestyles has been designed as a tetrahedron, its three lateral faces corresponding to the binomials food and nutrition, physical activity and rest, and education and hygiene. Each lateral face is divided into two triangles. These faces show the following: 1. food-based guidelines and healthy eating habits as related to a sustainable environment; 2. recommendations for rest and physical activity and educational, social and cultural issues; 3. selected hygiene and educational guidelines that, in conjunction with the other two faces, would contribute to better health and provide measures to promote environmental sustainability. The new FINUT pyramid is addressed to the general population of all ages and should serve as a guide for living a healthy lifestyle within a defined social and cultural context. It includes an environmental and sustainability dimension providing measures that should contribute to the prevention of non-communicable chronic diseases.A Organização Mundial da Saúde propôs a promoção e a proteção da saúde através do desenvolvimento de um ambiente que permita ações sustentáveis nos aspectos individuais, comunitários, nacionais e globais. De fato, diversos países desenvolveram diretrizes nutricionais baseadas em pirâmides alimentares, para a disseminação de informações nutricionais para a população em geral. No entanto, há também a necessidade de recomendações mais amplas, com informações sobre estilos de vida ativos e saudáveis, não apenas sobre a alimentação saudável. E objetivo do presente trabalho é propor uma pirâmide tridimensional como nova estratégia para a promoção da alimentação adequada e estilos de vida ativos e saudáveis de uma forma sustentável. Na verdade, a pirâmide de estilos de vida saudáveis da Fundação Ibero-Americana de Nutrição (FINUT) foi concebida como um tetraedro, com suas três faces laterais correspondendo aos aspectos de alimentação e nutrição, atividade física e repouso, e educação e higiene. Cada face lateral apresenta dois triângulos. Essas faces apresentam as seguintes informações: 1) diretrizes baseadas em alimentos e hábitos alimentares saudáveis relacionados a um meio-ambiente sustentável; 2) recomendações para repouso e atividade física e questões educacionais, sociais e culturais; e 3) diretrizes específicas sobre higiene e educação que, em conjunto com as outras duas faces, contribuiriam para a melhoria da saúde das pessoas em um planeta sustentável. A nova pirâmide FINUT é voltada para a população geral de todas as idades e deve servir como guia para um estilo de vida saudável, em um contexto social e cultural definido. Ela inclui uma dimensão ambiental e sustentável, fornecendo medidas que devem contribuir para a prevenção de doenças crônicas não transmissíveis

    Impacto psicológico de la emigración en América y Europa

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    [ES] Al emigrar las personas se ven expuestas a experiencias difíciles que repercuten en la salud psicológica pudiendo manifestar: ansiedad, depresión, baja autoestima, e incluso desarrollar el síndrome de Ulises. Objetivo: Identificar el impacto psicológico de los emigrantes en América y Europa. Metodología: Se llevó a cabo un estudio sobre datos migratorios de diversos países, proporcionados por el Departamento de Asuntos Económicos y Sociales de las Naciones Unidas. Resultados: La población de países latinoamericanos no siempre migra a los lugares más cercanos. Los mexicanos emigraron más a Norteamérica mientras que los venezolanos suelen viajar a países latinoamericanos. Conclusiones: Los emigrantes tienden a buscar mejores condiciones de vida, sin considerar el riesgo de perder sus derechos como personas
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