Relationships between Body Composition and Game Day Training Load in Ice Hockey Players

Body composition can impact physical activities and exercise performance. However, relationships between body composition and workload during ice hockey games remain unknown. PURPOSE: To examine relationships between body composition and game day training load in ice hockey players. METHODS: Eleven highly-trained ice hockey players (10 males, 1 female; mean ± standard deviation; age, 21.73 ± 1.34 yrs.; height, 179.93 ± 8.49 cm; body mass, 76.87 ± 14.38 kg, body fat percentage [BFP]: 18.0 ± 7.9% [mean ± SD]; fat-free mass index [FFMI]: 19.8 ± 2.2 kg/m2) participated in the study. First, participants visited the laboratory to assess their body composition by dual-energy X-ray absorptiometry and 3-dimensional optical imaging. Then, participants wore a player tracking device to monitor training load during an entire ice hockey game. Pearson correlations were utilized to assess relationships between selected body composition (body fat percentage [BFP], fat-free mass index [FFMI]) and training load metrics (average heart rate [HR], training impulse [TRIMP]). RESULTS: No statistically significant correlations between the selected body composition and training load variables were observed. Correlation coefficients were negative for the relationship between BFP and TRIMP (r = -0.46, p = 0.15) and between BFP and HR (r = -0.49, p = 0.12). In contrast, correlation coefficients were positive for the relationship between FFMI and TRIMP (r = 0.57, p = 0.07) and between FFMI and HR (r = 0.49, p = 0.12). CONCLUSION: With no statistically significant associations between training load and body composition, BFP and FFM might not impact workload in the ice hockey players during the game. However, further investigation will be necessary to establish this finding more definitively, due to the utilization of a single game’s training load and a modest sample of players

Characterization of Physical and Cognitive Performance and Hydration in Older Adults

In younger adults, dehydration has been shown to impair physical and cognitive performance. Older adults are habitually hypohydrated alongside experiencing physical and cognitive performance deficits. Despite these deficits, the link between these factors remains unexplored. Purpose: To examine the effect of hydration status on physical and cognitive performance in older adults. Methods: Sixteen (5 men and 11 women) community-dwelling adults (74±7yr; 78.2±15.0kg; 161±11cm) completed measurements of hydration status (urine specific gravity [USG], urine color), bioelectrical impedance analysis (lean mass, fat mass, total body fluid, intracellular to extracellular fluid ratio [ICF: ECF]), blood pressure, physical performance (handgrip strength test, sit-to-stand test, and a timed-up-and-go test), and reaction time (Flanker task). Hierarchical cluster analysis was performed on the distance matrix of USG and urine color to group participants. One-way ANOVAs were performed to determine differences among groups. Results: Hierarchical cluster analysis assigned participants to 4 groups (group1, n=3; group2, n=4; group3, n=5; group4,n=4). Consistent with the cluster analysis, each group had significantly (p1: 1.0±0.0, group2: 2.3±0.3, group3: 4.2±0.4, group4, 6.0±0.0). In addition, the reaction time was significantly different among groups. For group1, compatible and incompatible tasks (compatible: 1116±71.7s, p=0.049; incompatible: 1205±13.4ms, p=0.042) had a longer response time compared to group2(compatible: 640±67.5ms; incompatible: 688±74.0ms), group3 (compatible: 725±67.4ms; incompatible: 796±174.2ms), and group4 (compatible: 731±139.8ms; incompatible: 782±122.7ms). No significant differences were observed for lean mass, fat mass, total body fluid, ICF:ECF, blood pressure, handgrip strength, sit-to-stand test, and time-up-and-go test. Conclusion: Despite grouping by USG and urine color, no relationship was observed between body composition and physical performance. Surprisingly, hydrated individuals performed poorly cognitively compared to less hydrated individuals. We suggest these differences may reflect varying individual cognitive functions, not hydration status, among free-living older adults

Nested inversion polymorphisms predispose chromosome 22q11.2 to meiotic rearrangements [RETRACTED]

Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no such inversions have been uncovered as of yet. Using fiber-FISH, we demonstrate that parents transmitting the de novo 3 Mb LCR22A–D 22q11.2 deletion, the reciprocal duplication, and the smaller 1.5 Mb LCR22A–B 22q11.2 deletion carry inversions of LCR22B–D or LCR22C–D. Hence, the inversions predispose chromosome 22q11.2 to meiotic rearrangements and increase the individual risk for transmitting rearrangements. Interestingly, the inversions are nested or flanking rather than coinciding with the deletion or duplication sizes. This finding raises the possibility that inversions are a prerequisite not only for 22q11.2 rearrangements but also for all NAHR-mediated genomic disorders

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase&nbsp;1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation&nbsp;disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age&nbsp; 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score&nbsp; 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc&nbsp;= 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N&nbsp;= 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in&nbsp;Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in&nbsp;Asia&nbsp;and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

XVI International Congress of Control Electronics and Telecommunications: "Techno-scientific considerations for a post-pandemic world intensive in knowledge, innovation and sustainable local development"

Este título, sugestivo por los impactos durante la situación de la Covid 19 en el mundo, y que en Colombia lastimosamente han sido muy críticos, permiten asumir la obligada superación de tensiones sociales, políticas, y económicas; pero sobre todo científicas y tecnológicas. Inicialmente, esto supone la existencia de una capacidad de la sociedad colombiana por recuperar su estado inicial después de que haya cesado la perturbación a la que fue sometida por la catastrófica pandemia, y superar ese anterior estado de cosas ya que se encontraban -y aún se encuentran- muchos problemas locales mal resueltos, medianamente resueltos, y muchos sin resolver: es decir, habrá que rediseñar y fortalecer una probada resiliencia social existente - producto del prolongado conflicto social colombiano superado parcialmente por un proceso de paz exitoso - desde la tecnociencia local; como lo indicaba Markus Brunnermeier - economista alemán y catedrático de economía de la Universidad de Princeton- en su libro The Resilient Society…La cuestión no es preveerlo todo sino poder reaccionar…aprender a recuperarse rápido.This title, suggestive of the impacts during the Covid 19 situation in the world, and which have unfortunately been very critical in Colombia, allows us to assume the obligatory overcoming of social, political, and economic tensions; but above all scientific and technological. Initially, this supposes the existence of a capacity of Colombian society to recover its initial state after the disturbance to which it was subjected by the catastrophic pandemic has ceased, and to overcome that previous state of affairs since it was found -and still is find - many local problems poorly resolved, moderately resolved, and many unresolved: that is, an existing social resilience test will have to be redesigned and strengthened - product of the prolonged Colombian social conflict partially overcome by a successful peace process - from local technoscience; As Markus Brunnermeier - German economist and professor of economics at Princeton University - indicates in his book The Resilient Society...The question is not to foresee everything but to be able to react...learn to recover quickly.Bogot

MAGIC and H.E.S.S. detect VHE gamma rays from the blazar OT081 for the first time: a deep multiwavelength study

https://pos.sissa.it/395/815/pdfPublished versio

Research data supporting 'Structural insights into hybrid immiscible blends of metal-organic framework and sodium ultraphosphate glasses'

Data set contains information for Main text/manuscript data for most figures (fig 1-11) Fig 3: data obtained from B3 diffractometer, raw data converted to xy files using PowDLL. xy files for fig 3 can be directly opened in excel. xy files contain the PXRD patterns of the samples. OriginPro used to plot the figure. fig 6: excel spreadsheet data exported from Netzsch DSC software containing 2nd DSC upscans. Originpro used to plot the resulting figures. fig 7 and 8: D(r) files (final pair distribution functions) generating from GudrunX processing (information on processing in supplementary information and main text). These can be directly opened in excel. Originpro used to plot the resulting figures. Fig 9: excel spreadsheet containing all 31P and coupled 31P(1H) experiments. Directly plotted in OriginPro for final figure. Fig 10-11: data contained in excel spreadsheets, containing the depth profiles and young's moduli of the samples discussed in the manuscript. Originpro used to plot the resulting figures.Recently, increased attention has been focused on amorphous metal-organic frameworks (MOFs) and, more specifically, MOF glasses, the first new glass category discovered since the 1970s. In this work, we explore...</jats:p